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Biotech Business Week

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Lung Cancer



New lung cancer study findings have been reported from K. Dimakou et al



July 13th, 2009

"Adenosine deaminase (ADA) has been widely used for the diagnosis of tuberculous pleural effusion. Two isoenzymes have been described, ADA(1) and ADA(2)," researchers in Athens, Greece report.

"To evaluate the diagnostic value of sputum ADA, ADA, and ADA(2) activity in pulmonary tuberculosis (TB). We measured total ADA, ADA(1) and ADA(2) activity in the sputum of 27 patients with pulmonary TB (11 had a negative Ziehl-Neelsen stain for acid-fast bacilli [AFB]). Nineteen patients with lung cancer were used as controls. Sputum total ADA activity was significantly higher in TB than in lung cancer patients (median 18 U/l [range 3-70] vs. 6 U/l [2-16]; P< 0.001). Sputum...


Source: Biotech Business Week (2009-07-13)

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