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Biotech Business Week

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Diabetic Nephropathy



Research from Tokyo Women's Medical University in diabetic nephropathy provides new insights



July 13th, 2009

"Nitric oxide (NO) is thought to play an important role in the pathogenesis of diabetic nephropathy. We conducted a prospective, observational cohort study to explore the relationship between plasma levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase, and the development and progression of nephropathy in patients with type 2 diabetes," scientists in Tokyo, Japan report.

"This was a hospital-based observational cohort study in Japanese type 2 diabetic patients with normoalbuminuria [urinary albumin-to-creatinine ratio (ACR) < 30 mg/g creatinine] or microalbuminuria (30 <= ACR < 300 mg/g creatinine). The primary endpoint was the...


Source: Biotech Business Week (2009-07-13)

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