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Thrombophilia
Studies from Groningen University have provided new data on thrombophilia
July 13th, 2009
According to recent research published in the journal Blood, "Thrombophilia screening is controversial. In a retrospective family cohort, where probands had thrombosis and a thrombophilic defect, 2479 relatives were tested for thrombophilia." "In antithrombin-, protein C-, and protein S-deficient relatives, annual incidences of venous thrombosis were 1.77% (95% CI, 1.14-2.60), 1.52% (95% CI, 1.06-2.11), and 1.90% (95% CI, 1.32-2.64), respectively, at a median age of 29 years and a positive family history of more than 20% symptomatic relatives. In relatives with factor V (FV) Leiden, prothrombin 20210G >A, or high FVIII levels, these were 0.49% (95% CI,...
Source: Biotech Business Week (2009-07-13)
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