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Biotech Business Week

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Addiction Medicine



Studies from University of Cambridge yield new data on addiction medicine



July 13th, 2009

"Relapse is a hallmark feature of cocaine addiction and a main challenge for treatment strategies. Human studies indicate a link between impulsivity and increased susceptibility to relapse," investigators in Cambridge, the United Kingdom report.

"Rats were screened for high (HI) and low impulsivity (LI) on the 5-choice serial reaction time task. The HI and LI rats were trained to self-administer cocaine under a seeking-taking chained schedule: responses on the seeking lever resulted in presentation of the taking lever, responding upon which resulted in cocaine reinforcement. After the establishment of stable responding, an intermittent punishment schedule was...


Source: Biotech Business Week (2009-07-13)

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