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Escherichia coli
Study results from S.W. Linwu and colleagues update understanding of Escherichia coli
August 3rd, 2009
According to recent research published in the journal Biochemical Pharmacology, "Nitrobenzodiazepine (NBDZ) is a sedative-hypnotic drug used in the treatment of anxiety and sleep problems. Overdose of NBDZ may cause severe neurological effects, especially for people in drug abuse or addiction." "In the present study, we investigated NBDZ nitroreduction in rat enteric contents and characterized the role of enterobacterial nitroreductase in the reductive pathway. Nitroreduction of flunitrazepam (FZ) was studied in the microsomal membrane fractions of rat liver. jejunum and jejunal microflora using HPLC analysis. In the jejunal microflora, FZ was demonstrated to be...
Source: Biotech Business Week (2009-08-03)
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