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Vitae Pharmaceuticals, Inc.

Vitae Initiates Phase 1 Trial of Novel Renin Inhibitor

Published in Biotech Business Week, October 5th, 2009

Vitae Pharmaceuticals, Inc., an integrated discovery and development company, announced that it has initiated a Phase 1 clinical trial of its novel cardiovascular agent, VTP-27999.

VTP-27999 is a novel, proprietary renin inhibitor discovered and advanced by Vitae. "Renin inhibition offers a powerful approach to blood pressure control because renin is the first and rate limiting enzyme in the primary biochemical pathway for regulating the body's blood pressure", said Richard Gregg, MD, chief scientific officer at Vitae. "Also, renin is found in critical organs throughout the body such as the heart, brain and kidney. By inhibiting renin directly, VTP-27999 should provide...

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