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Biotech Law Weekly

Susan Hasty, Publisher

Table of Contents . . . March 26th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Law Weekly | Other Publications

Abbott Laboratories - Acquisition of TheraSense clears review; firm supports FDA's bar code rule

Advanced Viral Research Corp. - Patent granted for AIDS treatment

Astralis, Ltd. - Immunotherapeutics company files two patent applications

Boston Scientific Corp. - Guidant announces settlement of litigation

Chiron Corp. - Feds review complaints that Chiron hinders research

Congressional Pharmaceutical Corp. - Hollis-Eden announces acquisition

Ethics Violations - Income from outside sources to scientists must now be disclosed

Kaiser Family Foundation - Another survey confirms seniors are confused about new prescription drug law

Legislative Issues - New healthcare measures signed into law in New Mexico

London School of Hygiene and Tropical Medicine - Concerns over the value of animal experiments

Medical Marijuana - Lawmakers consider merits of legalizing medical marijuana

Medicare - Cancer patients brace for changes

Medicure, Inc. - Company receives ninth patent approval for treatment of cardiovascular diseases

Mental Health - Investigation into mental health launched in Connecticut

Novartis Pharmaceuticals Corp. - Drug that suppresses lactation blamed in woman's death

Abgenix, Inc. - Biotech company reports loss of $0.60 per share

Acacia Research Corporation - Alliance joins forces to develop diagnostic for Alzheimer disease

Adherex Technologies, Inc. - Cancer therapeutics company reports loss of $0.03 per share

Adolor Corporation - Entereg (alvimopan) receives FDA fast track designation

Agencourt Bioscience Corporation - Genomics company sponsors minority training program

Ajman University of Science and Technology - Time to change diabetic disease nomenclature

Akers Biosciences, Inc. - FDA clearance sought to market rapid heparin/platelet factor 4 test

Albert Einstein Hospital, Sao Paulo - Intergrons can aid epidemiological study of nosocomial infections

American College of Obstetricians & Gynecologists - ACOG issues new practice bulletin on chronic pelvic pain in women

Amersham - Biosciences firm broadens range of cellular analysis solutions

Anton Investments, Inc. - Nyer Medical Group closes subsidiary

Atrix Laboratories, Inc. - NDA submitted for 6-month prostate cancer product

Ben-Gurion University of the Negev - Gastric wall necrosis occurs following prolapse after laparoscopic banding

BioForce Nanosciences, Inc. - Nanotech company reports increased sales for January 2004

BioLase Technology, Inc. - Medical laser manufacturer announces offering of common stock

Bionomics Limited - Drug discovery deal to focus on ion channel targets

Biovail Corporation - Rights acquired to formulations of eprosartan, carvedilol

Boehringer Ingelheim (Canada) Ltd. - Novel nevirapine-like agents have improved activity against NNRTI-resistant HIV

Bradley Pharmaceuticals, Inc. - Pharmaceutical company's sales up 88%, earnings up 120%

Celgene Corporation - Thalomid multiple myeloma treatment sNDA accepted by FDA for review

Cell Genesys Inc. - Angiostatin gene therapy arrests tumor growth in experimental models

Celsion Corp. - Executive VP resigns from device firm

ChainDrugStore.net - Pharmaceutical company joins web-based retail pharmacy network

Chemical Exposure - Ohio study planned to detect levels of exposure to Teflon chemical

Cleveland Clinic Foundation - Mutated VG5Q gene heightens susceptibility to Klippel-Trenaunay syndrome

Clinical Trial Service Unit - Statins could reduce stroke risk by a third

Columbia University - Homeless children have high rates of asthma

CondomDepot.com - Condom retailer first to ban products containing nonoxynol-9

Cordis Corporation - Alliance with Guidant to combat coronary artery disease

Coronary Heart Disease - Studies look at CHD in women

Cutting Edge Information - Biogeneric approval on its way?

Cytopia - Companies hits cardiovascular program milestone

Daiichi Sunt Pharma Co. Ltd - Genetically engineered Escherichia coli produce tetrahydrobiopterin

Danish Cancer Society - Study finds no connection between cell phone use and risk of acoustic neuroma

Drug Use - 159 Milwaukee area drug-abuse deaths reported

Emergency Services - Rural communities struggle with underfunded ambulance services

Erasmus University Medical Center, Rotterdam - FoxO3a regulates erythroid differentiation via BTG1 expression

Ewha Woman's University Hospital - Estrogen production affords female rodents protection from kidney disease

Federal University of Sao Paulo - Restraint-induced stress increases homocysteine levels in rats

FiberGel Technologies - Eastern Illinois University to conduct Z-Trim research

Genentech, Inc. - FDA approves Avastin for first-line metastatic colorectal cancer patients

Genetronics BioMedical Corp. - Patient enrollment begins in phase III recurrent head and neck cancer studies

German Cancer Research Center - Certain brain tumors are clustered with other neoplasms in families

German Cancer Research Center - Familial incidence increases risk of developing urological cancers

German Institute of Nutritional Physiology - Amylin activates organs expressing receptor-activity modifying proteins

Given Imaging, Ltd. - Endoscope maker announces U.S. market clearance of pediatric accessory kit

Gulhane Medical School - Hearing impairment is complication of diabetes

HEE Corp. - Company inks exclusive distribution agreement for diabetes treatment

Hoag Memorial Hospital - Left intracranial tumors impair picture recognition memory

Hopital Necker-Enfants-Malades - Prevention strategies for childhood obesity outlined

Howard Hughes Medical Inst., Los Angeles -  M. tuberculosis DsbE protein characterized

Illegal Drugs - Las Vegas drug-related deaths on the rise

InSet Technologies - InfuMedics forms technology company

Infectious Diseases Society of America - Light-sensitive gloves reduce risk of germ transfer

Institut Curie - Glucocorticoid-induced kinase SGK inhibits mutant huntingtin toxicity

Institute Claudius Regaud, Toulouse - Diagnosing hereditary nonpolyposis colon cancer (HNPCC) is important

Johns Hopkins University - Smoking and diabetes differ in associations with atherosclerosis

KV Pharmaceutical Co. - Company announces agreement to market Gynazole-1 in China

Kanazawa Medical University - IL-6 overproduction linked to cardiac hypertrophy

Karolinska Hospital - Continuous hemodynamic monitoring can aid heart resynchronization

Karolinska Institute - Totally implantable subcutaneous port system can cause extensive bleeding

Kinki University - PAR-1-activating peptide facilitates pepsinogen secretion in rats

Kissei Pharmaceutical Co., Ltd. - MediciNova acquires phase II premature labor compound

Kosan Biosciences, Inc. - Maker of KOS-862 and 17-AAG reports $21.8 million revenue increase in 2003

Kyoto University - The efficacy of vector-based RNA interference is dose- and time-dependent

Kyushu University, Fukuoka - Two-loci or greater HLA mismatch associated with poor SCT outcome

Linkoping University - Stress can contribute to childhood diabetes

M.D. Anderson Cancer Center - New targeted agents in acute myeloid leukemia are more effective and less toxic

M.D. Anderson Cancer Center - Teens and young adults the new frontier in cancer, says U.S. specialist

MFIC Corp. - Microfluidizer company announces commencement of private placement

Mackay Memorial Hospital, Taipei - Three-dimensional ultrasound excludes midgut volvulus diagnoses in fetuses

Massachusetts General Hospital - Herpes simplex virus-based vectors help reporter genes track neurite activity

Massachusetts General Hospital - Newly approved bevacizumab strikes down rectal cancer vessel growth

Mayo Clinic - Lymphocyte dose correlated with survival after auto-SCT in NHL patients

Meiji Pharmaceutical University - Phloroglucinol from brown algae may treat diabetic complications

Memorial Univ. of Newfoundland - Low doses of woodchuck hepatitis virus target the lymphatic system

Minnesota Dept. of Public Health - Cough and cold care kits reduce antibiotic use

Nagoya City University - Extended periods of undetectable HBV DNA bode well for nonrelapse after therapy

National Institute of Health Science, Tokyo - In vitro farnesoid X receptor ligand sensor assay developed

National University of Singapore - Antisense suppression of DENN alters the growth of cancer cells and tumors

NeoRx Corp. - Cancer drug company announces $9.7 million common stock financing

New University of Lisbon - Novel SLC5A2 mutations cause autosomal recessive renal glucosuria

Nippon Medical College, Tokyo - Parasympathetic blockade aids recovery from RAP-induced ERP shortening

North General Hospital, Sheffield - Ferrous sulphate treatment of anemia after joint replacement is of no value

Northwestern University, Evanston - Downregulated p53 and Rb is required for trophoblast giant cell differentiation

Novartis Institute of Medical Science - COX-2 inhibitors may be promising in treating bone cancer pain

Novo Nordisk - Repaglinide plus pioglitazone improves blood glucose control, study shows

Ohio State University - IFN-I not needed for anti-TB responses in aged mice

Oncolytics Biotech Inc. - Biotechnology company receives approval to begin U.K. phase I cancer trial

OraSure Technologies, Inc. - Distribution agreement dispute resolved for OraQuick Rapid HIV-1 Antibody Test

Osaka Medical College - Chymase inhibition prevents adhesion formation after abdominal surgery

Pacific Biometrics, Inc. - Research services company closes on $1.9M private placement

PamGene International B.V. - Questra device management software designed for drug development market

Par Pharmaceutical, Inc. - FDA issues approvable letter for ribavirin capsules

Paratek Pharmaceuticals, Inc. - Collaboration to discover novel antimalarial compounds

Pardubice University - Measurements of temporal bone structures define standard growth characteristics

Pasteur Institute of Bangui, Paris - HIV rates high in both rural and urban Central African Republic

Pennsylvania State University - Study suggests better use of web could improve epidemiological tracking

Personnel - Integrated Healthcare Systems names Robin L. Krueger as CFO

RIKEN Center for Developmental Biology - "Rich" genes travel more

Refocus Group, Inc. - Phase II clinical trials begin for potential presbyopia treatment

Roswell Park Cancer Inst. - Selenium disrupts androgen receptor signaling in prostate cancer

Roswell Park Cancer Institute - Prostate-derived Ets exhibits strong tumor association

Russian Academy of Medical Science - Frequent hypermethylation of TIMP-2 gene may promote cervical cancer development

Russian Academy of Sciences - Tropomyosin-encoding gene expression depends on vasopressin gene

Sabex Inc. - Pharmaceutical company announces new chief executive officer

Schering, AG, Germany - Imaging Diagnostic Systems installs additional CTLM system

Seattle Genetics, Inc. - Manufacturing agreement announced for monoclonal antibody product candidate

Security Biometrics, Inc. - Electronic prescriptions application geared to reduce prescription errors

Showa Pharmaceutical Univ., Tokyo - Basal transcription of rat AT1A receptor gene characterized

Sicel Technologies - Grant to fund development of implantable sensor technology for oncology

Spectral Diagnostics Inc. - Diagnostics company reports third quarter financial results

Spectrum Pharmaceuticals, Inc. - Satraplatin shows in vitro efficacy in taxane-resistant tumor cells

St. Jude Children's Research Hospital - Protein's role in retina development key to understanding devastating eye cancer

St. Jude Medical, Inc. - Medical device manufacturer announces new member of board of directors

St. Luke's Roosevelt Hospital - Folic-acid fortification policy a great success in reducing neural tube defects

Stanford University - Researchers find genetic subtypes of prostate cancer

Stressgen - HspE7 lengthens time between papillomatosis surgeries, data shows

SuperGen Inc. - Nipent European marketing authorizations acquired

Swiss Tropical Institute - Development of artemether resistance slow and reversible in mice

Tampa General Hospital - Special considerations challenge the treatment of epilepsy in women

Tokyo Women's Medical University - Post-SCT eosinophilic pustular folliculitis described

Tottori University - p53 links proteasome system and neuronal death in Parkinson disease

U.S. Centers for Disease Control & Prevention - Short supply of childhood meningitis drug

U.S. Food & Drug Administration - NeuC protein of E. coli K1 is UDP N-acetylglucosamine 2-epimerase

U.S. National Institute on Drug Abuse - Adenosine, dopamine receptors not involved in CGS 21680 cardiovascular effects

U.S. National Institutes of Health - DNA vaccine enhances Th1 immune response against hepatitis C virus

United Surgical Partners Intl., Inc. - Surgical facilities operator announces new chief executive officer

Univ. of Bologna Alma Mater Studiorum - Liver disease is common in patients treated in metabolic departments

Univ. of California, Davis - Macaque SHIV model could aid research on env gene, pediatric infection

Univ. of California, Los Angeles - Gene therapy protects livers from transplant-related injury

Univ. of California, Los Angeles - Women's well-being worse after mastectomy, chemotherapy, than lumpectomy

Univ. of Chicago Medical Center - Widely used antinausea drug may interfere with chemotherapy

Univ. of Texas SW Medical Center - Researchers receive NIH grant to open research center

University of Bristol - Breastfeeding linked with lower childhood blood pressure

University of Chicago - Autologous repair of supravalvar pulmonary stenosis feasible

University of Coimbra - Organochlorine pesticides quantified in human serum from Portugal

University of Cologne - As many as 95% of Hodgkin disease patients can be cured with modern therapy

University of Dusseldorf - Percutaneous gene delivery expands transgene expression in rodent hearts

University of Georgia - Real-time PCR quantifies uncoupling protein expression in fat tissue

University of Gothenburg - Systolic murmurs predict mortality in elderly women

University of Lausanne - Open capsulolabral reconstruction results in stable shoulder joints

University of London - Different resistance mutations seen in blood and lungs of HIV patients

University of Manchester - Plantar tissue thickness predicts plantar pressure in diabetic foot

University of Michigan - New drugs limit deadly effects of graft-vs.-host disease

University of Michigan - Vascular endothelial growth factor supports regenerated nerves after grafting

University of Munich - VEGF levels rise in the serum of patients with HIV-linked neurological disease

University of Munster - Cyclin E overexpression in some cancers means proliferation and poor prognosis

University of North Carolina - KSHV K1 protein activates Akt cell survival pathway

University of North Carolina - New DVD virtual microscope developed at school of medicine

University of Padua - Predictive medicine should include malignant, nonmalignant urological disorders

University of Portsmouth - Insight into lupus antigen protein offered

University of Saarland - Cationic nanospheres are an alternative to negatively charged DNA carriers

University of Sheffield - Study: Women live beyond childbearing years to ensure reproductive fitness

University of Southern Denmark - Arachidonic acid inhibition of adipocyte differentiation requires PKA

University of Toronto - Study evaluates psychosocial functioning in women after prophylactic mastectomy

University of Ulm Clinic - Regional and topical anesthesia are more widely used in ophthalmology

University of Washington - Growth factor may link two paralyzing disorders

University of Washington - PET clarifies regional sympathetic function during heart disease

University of Zurich - Athersclerosis in the radial artery contraindicates its use in bypass grafting

Uppsala University - Children and young adults with myelomeningocele have reaching difficulties

Uppsala University - Understanding of mechanism of systemic amyloidoses offers therapy hope

VA San Diego Healthcare System - Radiation safety guidelines are needed for sentinel lymph node procedures

Vanderbilt Univ. Medical Center - JAK2-STAT5 signaling needed for microglia activation by IL-3

Vanderbilt University - Deletion of selenoprotein P gene results in neurological dysfunction

Varian, Inc. - More sensitive diphenyl column added to laboratory consumable products line

Ventaira Pharmaceuticals - Board appoints Leslie J. Williams chief operating officer at pharmaceutical firm

Ventana Medical Systems Inc. - Clinical systems manufacturer announces outcome of injunction hearing

Veridien Corporation - Health care company invests in anti-infectives/drug development company

Verispan - New product reports measures of prescription activity at plan/payer level

Villingen-Schwenningen Clinical Center - Bladder disorder therapy should aim for social continence in those with dementia

Washington University - First avian genome now available to scientists worldwide

Wayne State University - Palatal augmentation prostheses helps speech and swallowing after glossectomy

Weill Cornell Medical School - Investigators find way to improve the care of depression in the elderly

Windber Research Institute - Multiple biomarkers may be necessary to classify breast cancer

Women's & Children's Hospital, Adelaide - Modified stem cells treat the neurological symptoms of lysosomal storage disease

Wyeth Vaccines - CDC recommends suspension of third and fourth doses of Prevnar

Zengen, Inc. - Study reviews new approach to control inflammation using melanocortin receptors

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