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Biotech Law Weekly

Susan Hasty, Publisher

Table of Contents . . . April 30th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Law Weekly | Other Publications

BTG - Fulcrum Pharma named preferred provider of drug development services

Barr Laboratories, Inc. - Kos files suit for infringement of new Niaspan patent

BioGentech Corp. - Australian patent issued covering use of Cyanocobalamin for allergies

Cutting Edge Information - Blending of branded and generic pharmaceutical industries expected to continue

DrugAbuse Sciences SAS - New European patent granted for naltrexone

Gift Awards - Eli Lilly gives $6 million to group that sued a year ago

Healthcare Coverage - AmeriHealth New Jersey approved to offer Medicare drug-discount cards

Healthcare Coverage - Health Net offers Medicare-endorsed drug discount programs for seniors

Healthcare Coverage - LTCPA wins Medicare endorsement for prescription drug card

Healthcare Coverage - PharmaCare to offer Medicare-approved drug discount card program

Healthcare Coverage - UCare Minnesota to offer Medicare-approved drug discount card

Innogenetics, NV - Genencor sells its therapeutic vaccine program in multimillion dollar deal

Kibow Biotech, Inc. - Company secures patents for gut-based uremia therapy products

Medicaid - Loophole lets drug companies avoid Medicaid program's restriction list

Medicare - CMS adds to list of outpatient services eligible for additional payments

Aastrom Biosciences, Inc. - Clinical trial initiated in Spain for bone grafting

Aegera Therapeutics, Inc. - Phase I trial of XIAP initiated

Applied Medical Resources Corp. - Australian medical/surgical products distributor acquired

Array BioPharma, Inc. - Data: Investigational MEK inhibitor AZD6244 combats cancer growth

Arrow International, Inc. - NanoHorizons to partner on nanobiomedical device development

Aventis - FDA approval granted for Ketek (telithromycin) tablets

Axcan Pharma, Inc. - European approval granted for Photobarr

BodyMedia Inc. - Diabetes and obesity body monitoring technologies to extend to remote areas

Boston Biomedica, Inc. - Biotech firm reports 2.3% increase in revenue

Boston University - Missed opportunities for addressing HIV testing remain unacceptably high

Business & Finance - North Carolina officials deny drug company donations affect policy

Cardiac Arrhythmias - Mouse study shows plugging calcium leak may prevent deadly irregular heartbeat

CardioTech International, Inc. - Update provided on coronary artery bypass graft clinical trials

Case Western Reserve University - Researchers make major gain in understanding how prions jump species

Cell Signaling Technology, Inc. - Marketing, distribution deal signed to expand line of kinase assays, enzymes

Center for the Advancement of Genomics - HP enters partnership to further genomic discovery in life science

Center of Oncology, Poland - Ku86 levels correlate with magnitude of radiation-induced lymphocyte DNA breaks

Cerus Corp. - Data demonstrate vaccine technology's potential to treat/prevent cancer

Children's Hospital Seattle - TV linked to kids' attention problems

Chindex International, Inc. - Healthcare products distributor reports $13.5M private placement

Cincinnati Children's Hospital - Role of CD40L dysregulation in HIV-induced APC dysfunction reviewed

Claude Bernard University - MEK-1/ERK signals have differential effects on erythroid progenitor self-renewal

Commonwealth Fund - Over 40% of Midwestern U.S. adults report problems paying medical bills

Connecticut Children's Medical Center - Endoscopic third ventriculostomy is feasible for aqueductal stenosis

Corus Pharma - Pharmaceutical firm appoints Richard B. Brewer to board of directors

Cubist Pharmaceuticals, Inc. - Safety review of endocarditis/bacteremia data for Cubicin complete

DMI BioSciences, Inc. - License agreement signed with BiOracle diagnostic test

DNAPrint genomics - Joint research program signed with H. Lee Moffitt Cancer Center

Dana Farber Cancer Institute - p185/Cu17-binding-defective Tag mutants unable to transform fibroblasts

Dharmacon, Inc. - Fisher Scientific completes acquisition of RNAi technology company

Disease Outbreaks - Nebraska Medical Center experts warn of new, old disease threats

Drexel University - Merozoite surface proteins differ in ability to protect against malaria

Duke University - Novel MRI technique provides clear images of blood flow

Dynavax Technologies Corporation - Allergy drug maker reports loss of $18M

EMD Biosciences, Inc. - Proteoplex 16-Well Human Cytokine Array Kit launched

Eisai Co., Ltd. - Anti-epileptic drug Zonegran acquired from Elan

Erasmus Medical Center - Vaccinia virus expressing RSV genes does not predispose for immunopathology

Express Scripts, Inc. - Antidepressant use in children and adolescents continues to grow, study shows

Food Technology Service, Inc. - Irradiation company reports 56% increase in 2003 revenues

Fred Hutchinson Cancer Research Center - Cytotoxic T cells inactivated by HSV-infected cells

Genta, Inc. - Cancer-therapeutics company files shelf registration statement

German Cancer Research Center - Study offers new insights into the mechanisms of rapamycin

Guidant Corp. - Carotid stenting to prevent stroke safe and effective

Guilford Pharmaceuticals Inc. - Pfizer terminates NAALADase license agreement

HIV/AIDS - Grant benefits Nevada AIDS program

Harvard University - Intracellular transport of HIV integrase elucidated

Harvard University - Surgery for gallbladder cancer generally has a poor prognosis

Himeji Institute Technology - Field-enhanced sample injection method developed for protein analysis

Hoffmann-La Roche Inc. - Pharmaceutical company announces vice president, research, metabolic diseases

Hospital Clinic, Barcelona - Stress fractures misdiagnosed as tumoral or infectious processes

Huddinge Hospital - Gene profiles in mucosa identified during H. pylori infection

Human Genome Sciences, Inc. - Agreement inked for development of pharmacogenomic diagnostic assays

IMM BioSciences Asia, Ltd. - ImmuneRegen establishes research entity in Singapore

ImaRx Therapeutics, Inc. - Company completes private placement to advance NanoInvasive surgery

Impax Laboratories - Branded drug-makers prepare for the inevitable

Ingenium Pharmaceuticals, AG - Company to provide Merck with genetic rat models

Institut Curie, Paris - Histological margin assessment for breast cancer reviewed

Isis Innovation - Deep organ image MR scan developed

Johns Hopkins University - One in 12 diabetics over age 40 has vision-threatening eye disease

Johns Hopkins University - Spikes in blood pressure during exercise occur when cells can't "relax"

Kyoto University - Munc13-4 regulates dense core granule secretion in platelets

Linkoping University - Waterborne norovirus outbreak in Sweden described

Ludwig-Maximilians-University Munich - Activation of toll-like receptor-9 induces progression of renal disease

Luther Needlesafe Products, Inc. - Med-Design acquires Low Profile Safety Huber Needle

M.D. Anderson Cancer Center - INO-1001, novel inhibitor of PARP, enhances radiation sensitivity

MDS Nordion - Company announces first North American sales of Raycell blood irradiator

MIV Therapeutics, Inc. - Hemolysis test produces successful results for Hap technology

Marshall Edwards, Inc. - Studies: Phenoxodiol produces response and restores chemosensitivity

Maxim Pharmaceuticals - Preclinical results presented for vascular targeting agent MX116407

Mayo Clinic - Researchers develop a murine model for polyethylene-induced osteolysis

Medical College of Wisconsin - Rat model of diabetic nephropathy characterized

Medical University of South Carolina -  C. perfringens alphaNAG converts type A2 blood cells to type O

Memorial Sloan-Kettering Cancer Center - ADAM10 and ADAM17 crucial in ectodomain shedding of six EGFR ligands

Memorial Sloan-Kettering Cancer Center - LPAM integrin is important in graft-versus-host disease development

Merck Research Laboratories - Expression of potassium channels in pancreatic islets described

Millenium Biologix, Inc. - Skelite orthopedic products win CE mark

NPS Pharmaceuticals, Inc. - Positive phase III data reported for PREOS

National Taiwan University Hospital - HBV genomic variability not seen to exacerbate chronic hepatitis B

Natl. Inst. of Public Health & the Environment, Bi - Beijing genotype linked with high TB relapse risk in Vietnam

NeoPharm, Inc. - "Tandem technology" delivers two drugs simultaneously into cancer cells

New York University - PTSD increases in children with extended ICU stays after cardiac surgery

Northwestern University - E-cadherin is important in prostate cancer cell invasion

Northwestern University - Tobacco use fingered as culprit in lung cancer increase in women

Novoste Corporation - Novoste announces staff reduction, resignation of chief operating officer

Obesity - Californians show concern over childhood obesity, study shows

Odense University Hospital - Reduced lipid oxidation in type 2 diabetes may be of genetic origin

Orphan Medical, Inc. - Xyrem marketing authorization application accepted for review in Europe

Partners AIDS Research Center - Children may have enhanced responses to anti-HIV immunotherapy

Patents - Appeals court upholds Genentech patent victory

PediaMed Pharmaceuticals, Inc. - Pediatric-focused pharma company promotes Martin P. Manco

Peking University - Novel real-time PCR assay enhances detection of SARS coronovirus

Personnel - Hythiam names Monica Alfaro Welling as VP of marketing

Pfizer Inc - Pharmaceutical company to be included in Dow Jones Industrial Average

Portland VA Hospital - Screening can essentially prevent colorectal cancer

Prescription Drug Importation - Wisconsin city studies getting prescription drugs from Canada

Queen Elizabeth Hospital, Birmingham - Risk factors and recurrence of primary biliary cirrhosis

Quorex Pharmaceutical - Indazole-derived SAH/MTA nucleosidase inhibitors have antimicrobial activity

RITA Medical Systems, Inc. - RFA for breast cancer shows promise as minimally invasive treatment

Rand Corp. - Improving treatment creates long-lasting improvements for minority patients

Raven Biotechnologies, Inc. - Biotechnology company announces monoclonal antibody candidate

Rensselaer Polytechnic Institute - New software predicts promising ingredients for new drugs

Roche - Partnership plans to target cancer cells through the E2F pathway

Rush-Presbyterian St. Luke's Med. Center, Chicago - Ceramic-metal coupled hip components do not increase fretting corrosion

Santa Maria Croci Hospital - Early, high-dose chemotherapy with HPCS effective for poor prognosis GCT

Second University of Naples - Embryonal rhabdomyosarcoma of the tongue reported in elderly man

Serono, Inc. - Serostim improves lean body mass in HIV-associated wasting, study shows

St. Jude Children's Hospital - PET-CT for pediatric oncology is implemented in a tertiary care center

St. Jude Children's Hospital, Memphis - Crystal structure of M. tuberculosis PPAT determined

Substance Abuse - Depressed young women at highest risk of alcohol abuse

Telik, Inc. - Telcyta phase III registration trial initiated in NSCLC

Teva Pharmaceutical Industries Ltd. - Initial commercialization of Oxycodone 80 mg announced

The Medical Letter - Adverse drug interactions program launched

Thomas Jefferson University - Molecular profiling reveals novel genes linked to glomerular disease

ThromboGenics Ltd. - FDA grants orphan drug designation for microplasmin in pediatric eye surgery

Transoma Medical - $375,000 grant awarded to train employees for medical device market

Trubion Pharmaceuticals, Inc. - Biopharmaceutical company names new senior VP of clinical development

Tulane University - Genetic markers for obesity confirmed

U.S. Centers for Disease Control & Prevention -  Mycobacterium tuberculosis cultures may represent cross contamination

U.S. National Cancer Institute - Pheophorbide is specific probe for measuring ABCG2 function and inhibition

U.S. National Institutes of Health - Acute immune response to filarial parasites characterized by Th1 cytokines

Univ. of California, Davis - Trypanosome microtubule-associated protein p15 is vaccine candidate

Univ. of California, Los Angeles - Doctors likely to delay prescribing antiretrovirals for women, minorities

Univ. of Innsbruck Hospital - New anastomosis technique is reliable for vascular anastomosis

Univ. of Rochester Medical Center - Comprehensive study: We know little about environment's effects on kids

Univ. of Rochester Medical Center - Newer drugs more effective at curing strep throat than penicillin

Univ. of Texas, Dallas - Lack of specific brain protein causes marked deficits in learning, memory

University Hospital of Grenoble - New clues for glioma treatment found

University of Aberdeen - Requirements for leukocyte passage across blood-retina barrier described

University of Alabama Hospital - Epidemiology of Aspergillus terreus at university hospital described

University of Alberta - Further studies comparing rehydration therapies would waste resources

University of Barcelona - Trefoil peptide reduces VCAM-1 expression in intestinal inflammation

University of Copenhagen - Dissociation found between insulin resistance and insulin signaling

University of Ferrara - Post-HSCT dendritic cell recovery kinetics determined

University of Florida - Researchers use gel to deliver gene therapy to diaphragm muscle

University of Genoa - CD59 acts as co-receptor in natural killer cell activation

University of Glasgow - Exercise and postprandial lipid metabolism reviewed

University of Homburg - Oral medications are preferred for treating most cases of erectile dysfunction

University of Iowa - Diet rich in lean beef improves serum ferritin levels in adolescents

University of Klinikums Munster - Retrograde ureteropyelography demonstrates fibroepithelioma of left ureter

University of Leipzig - Blood test useful for monitoring immunosuppressant interactions

University of London - Low B12 linked with poor memory in people with high-risk genotype

University of Massachusetts -  Haemophilus influenzae protein complex induces cytokine production

University of Michigan - Susceptibility loci for type 2 diabetes found on chromosomes 6, 11, 14A

University of Montpellier - Interaction between mannose receptors and C. albicans clarified

University of North Carolina - BMI superior obesity measure, but pediatricians not using it enough

University of Ottawa - Prevention and genetic testing for breast cancer vary geographically

University of Oviedo - Role of endothelin in inflammatory hyperalgesia in mice described

University of Oxford - Type 2 diabetes onset maps to chromosome 12p and locus on 12q24

University of Pennsylvania - Idiopathic thrombocytopenic purpura therapy reviewed

University of Rome "La Sapienza" - Plant-derived liminoids exhibit potent antiretroviral activity

University of Salerno - NF-kappaB/Rel-mediated apoptosis regulation reviewed

University of Southern California - USC awarded $3.5 million to study DNA enzyme

University of Toronto - New genes linked to gut problems

Valentis, Inc. - Patient enrollment completed for Deltavasc phase II trial

Varian Medical Systems, Inc. - Assets of OpTx Corporation acquired

Vela Pharmaceuticals Inc. - Late-stage molecule licensed for the treatment of depression

Vital Living Corporation - Nutraceuticals company announces increased operating revenue for 2003

Waife & Associates, Inc. - Management consulting company announces new clinical operations associate

Washington University - Combining scans improves radiologists' targeting of lung tumors

Wonkwang University - Liquid chromatography-mass spec used to study antiangiogenic drug in rat model

Wyeth Pharmaceuticals - Four neuroscience compounds to be co-developed and co-commercialized

Xanthus Life Sciences - C-1311 shows preclinical anticancer activity for colon cancer treatment

YM BioSciences Inc. - Drug development company selects chair for breast cancer trial

Yale University - Study suggests managed-care approach may reduce treatment effectiveness

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