Susan Hasty, Publisher
Table of Contents . . . April 30th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Biotech Law Weekly | Other Publications
BTG - Fulcrum Pharma named preferred provider of drug development services
Barr Laboratories, Inc. - Kos files suit for infringement of new Niaspan patent
BioGentech Corp. - Australian patent issued covering use of Cyanocobalamin for allergies
Cutting Edge Information - Blending of branded and generic pharmaceutical industries expected to continue
DrugAbuse Sciences SAS - New European patent granted for naltrexone
Gift Awards - Eli Lilly gives $6 million to group that sued a year ago
Healthcare Coverage - AmeriHealth New Jersey approved to offer Medicare drug-discount cards
Healthcare Coverage - Health Net offers Medicare-endorsed drug discount programs for seniors
Healthcare Coverage - LTCPA wins Medicare endorsement for prescription drug card
Healthcare Coverage - PharmaCare to offer Medicare-approved drug discount card program
Healthcare Coverage - UCare Minnesota to offer Medicare-approved drug discount card
Innogenetics, NV - Genencor sells its therapeutic vaccine program in multimillion dollar deal
Kibow Biotech, Inc. - Company secures patents for gut-based uremia therapy products
Medicaid - Loophole lets drug companies avoid Medicaid program's restriction list
Medicare - CMS adds to list of outpatient services eligible for additional payments
Aastrom Biosciences, Inc. - Clinical trial initiated in Spain for bone grafting
Aegera Therapeutics, Inc. - Phase I trial of XIAP initiated
Applied Medical Resources Corp. - Australian medical/surgical products distributor acquired
Array BioPharma, Inc. - Data: Investigational MEK inhibitor AZD6244 combats cancer growth
Arrow International, Inc. - NanoHorizons to partner on nanobiomedical device development
Aventis - FDA approval granted for Ketek (telithromycin) tablets
Axcan Pharma, Inc. - European approval granted for Photobarr
BodyMedia Inc. - Diabetes and obesity body monitoring technologies to extend to remote areas
Boston Biomedica, Inc. - Biotech firm reports 2.3% increase in revenue
Boston University - Missed opportunities for addressing HIV testing remain unacceptably high
Business & Finance - North Carolina officials deny drug company donations affect policy
Cardiac Arrhythmias - Mouse study shows plugging calcium leak may prevent deadly irregular heartbeat
CardioTech International, Inc. - Update provided on coronary artery bypass graft clinical trials
Case Western Reserve University - Researchers make major gain in understanding how prions jump species
Cell Signaling Technology, Inc. - Marketing, distribution deal signed to expand line of kinase assays, enzymes
Center for the Advancement of Genomics - HP enters partnership to further genomic discovery in life science
Center of Oncology, Poland - Ku86 levels correlate with magnitude of radiation-induced lymphocyte DNA breaks
Cerus Corp. - Data demonstrate vaccine technology's potential to treat/prevent cancer
Children's Hospital Seattle - TV linked to kids' attention problems
Chindex International, Inc. - Healthcare products distributor reports $13.5M private placement
Cincinnati Children's Hospital - Role of CD40L dysregulation in HIV-induced APC dysfunction reviewed
Claude Bernard University - MEK-1/ERK signals have differential effects on erythroid progenitor self-renewal
Commonwealth Fund - Over 40% of Midwestern U.S. adults report problems paying medical bills
Connecticut Children's Medical Center - Endoscopic third ventriculostomy is feasible for aqueductal stenosis
Corus Pharma - Pharmaceutical firm appoints Richard B. Brewer to board of directors
Cubist Pharmaceuticals, Inc. - Safety review of endocarditis/bacteremia data for Cubicin complete
DMI BioSciences, Inc. - License agreement signed with BiOracle diagnostic test
DNAPrint genomics - Joint research program signed with H. Lee Moffitt Cancer Center
Dana Farber Cancer Institute - p185/Cu17-binding-defective Tag mutants unable to transform fibroblasts
Dharmacon, Inc. - Fisher Scientific completes acquisition of RNAi technology company
Disease Outbreaks - Nebraska Medical Center experts warn of new, old disease threats
Drexel University - Merozoite surface proteins differ in ability to protect against malaria
Duke University - Novel MRI technique provides clear images of blood flow
Dynavax Technologies Corporation - Allergy drug maker reports loss of $18M
EMD Biosciences, Inc. - Proteoplex 16-Well Human Cytokine Array Kit launched
Eisai Co., Ltd. - Anti-epileptic drug Zonegran acquired from Elan
Erasmus Medical Center - Vaccinia virus expressing RSV genes does not predispose for immunopathology
Express Scripts, Inc. - Antidepressant use in children and adolescents continues to grow, study shows
Food Technology Service, Inc. - Irradiation company reports 56% increase in 2003 revenues
Fred Hutchinson Cancer Research Center - Cytotoxic T cells inactivated by HSV-infected cells
Genta, Inc. - Cancer-therapeutics company files shelf registration statement
German Cancer Research Center - Study offers new insights into the mechanisms of rapamycin
Guidant Corp. - Carotid stenting to prevent stroke safe and effective
Guilford Pharmaceuticals Inc. - Pfizer terminates NAALADase license agreement
HIV/AIDS - Grant benefits Nevada AIDS program
Harvard University - Intracellular transport of HIV integrase elucidated
Harvard University - Surgery for gallbladder cancer generally has a poor prognosis
Himeji Institute Technology - Field-enhanced sample injection method developed for protein analysis
Hoffmann-La Roche Inc. - Pharmaceutical company announces vice president, research, metabolic diseases
Hospital Clinic, Barcelona - Stress fractures misdiagnosed as tumoral or infectious processes
Huddinge Hospital - Gene profiles in mucosa identified during H. pylori infection
Human Genome Sciences, Inc. - Agreement inked for development of pharmacogenomic diagnostic assays
IMM BioSciences Asia, Ltd. - ImmuneRegen establishes research entity in Singapore
ImaRx Therapeutics, Inc. - Company completes private placement to advance NanoInvasive surgery
Impax Laboratories - Branded drug-makers prepare for the inevitable
Ingenium Pharmaceuticals, AG - Company to provide Merck with genetic rat models
Institut Curie, Paris - Histological margin assessment for breast cancer reviewed
Isis Innovation - Deep organ image MR scan developed
Johns Hopkins University - One in 12 diabetics over age 40 has vision-threatening eye disease
Johns Hopkins University - Spikes in blood pressure during exercise occur when cells can't "relax"
Kyoto University - Munc13-4 regulates dense core granule secretion in platelets
Linkoping University - Waterborne norovirus outbreak in Sweden described
Ludwig-Maximilians-University Munich - Activation of toll-like receptor-9 induces progression of renal disease
Luther Needlesafe Products, Inc. - Med-Design acquires Low Profile Safety Huber Needle
M.D. Anderson Cancer Center - INO-1001, novel inhibitor of PARP, enhances radiation sensitivity
MDS Nordion - Company announces first North American sales of Raycell blood irradiator
MIV Therapeutics, Inc. - Hemolysis test produces successful results for Hap technology
Marshall Edwards, Inc. - Studies: Phenoxodiol produces response and restores chemosensitivity
Maxim Pharmaceuticals - Preclinical results presented for vascular targeting agent MX116407
Mayo Clinic - Researchers develop a murine model for polyethylene-induced osteolysis
Medical College of Wisconsin - Rat model of diabetic nephropathy characterized
Medical University of South Carolina - C. perfringens alphaNAG converts type A2 blood cells to type O
Memorial Sloan-Kettering Cancer Center - ADAM10 and ADAM17 crucial in ectodomain shedding of six EGFR ligands
Memorial Sloan-Kettering Cancer Center - LPAM integrin is important in graft-versus-host disease development
Merck Research Laboratories - Expression of potassium channels in pancreatic islets described
Millenium Biologix, Inc. - Skelite orthopedic products win CE mark
NPS Pharmaceuticals, Inc. - Positive phase III data reported for PREOS
National Taiwan University Hospital - HBV genomic variability not seen to exacerbate chronic hepatitis B
Natl. Inst. of Public Health & the Environment, Bi - Beijing genotype linked with high TB relapse risk in Vietnam
NeoPharm, Inc. - "Tandem technology" delivers two drugs simultaneously into cancer cells
New York University - PTSD increases in children with extended ICU stays after cardiac surgery
Northwestern University - E-cadherin is important in prostate cancer cell invasion
Northwestern University - Tobacco use fingered as culprit in lung cancer increase in women
Novoste Corporation - Novoste announces staff reduction, resignation of chief operating officer
Obesity - Californians show concern over childhood obesity, study shows
Odense University Hospital - Reduced lipid oxidation in type 2 diabetes may be of genetic origin
Orphan Medical, Inc. - Xyrem marketing authorization application accepted for review in Europe
Partners AIDS Research Center - Children may have enhanced responses to anti-HIV immunotherapy
Patents - Appeals court upholds Genentech patent victory
PediaMed Pharmaceuticals, Inc. - Pediatric-focused pharma company promotes Martin P. Manco
Peking University - Novel real-time PCR assay enhances detection of SARS coronovirus
Personnel - Hythiam names Monica Alfaro Welling as VP of marketing
Pfizer Inc - Pharmaceutical company to be included in Dow Jones Industrial Average
Portland VA Hospital - Screening can essentially prevent colorectal cancer
Prescription Drug Importation - Wisconsin city studies getting prescription drugs from Canada
Queen Elizabeth Hospital, Birmingham - Risk factors and recurrence of primary biliary cirrhosis
Quorex Pharmaceutical - Indazole-derived SAH/MTA nucleosidase inhibitors have antimicrobial activity
RITA Medical Systems, Inc. - RFA for breast cancer shows promise as minimally invasive treatment
Rand Corp. - Improving treatment creates long-lasting improvements for minority patients
Raven Biotechnologies, Inc. - Biotechnology company announces monoclonal antibody candidate
Rensselaer Polytechnic Institute - New software predicts promising ingredients for new drugs
Roche - Partnership plans to target cancer cells through the E2F pathway
Rush-Presbyterian St. Luke's Med. Center, Chicago - Ceramic-metal coupled hip components do not increase fretting corrosion
Santa Maria Croci Hospital - Early, high-dose chemotherapy with HPCS effective for poor prognosis GCT
Second University of Naples - Embryonal rhabdomyosarcoma of the tongue reported in elderly man
Serono, Inc. - Serostim improves lean body mass in HIV-associated wasting, study shows
St. Jude Children's Hospital - PET-CT for pediatric oncology is implemented in a tertiary care center
St. Jude Children's Hospital, Memphis - Crystal structure of M. tuberculosis PPAT determined
Substance Abuse - Depressed young women at highest risk of alcohol abuse
Telik, Inc. - Telcyta phase III registration trial initiated in NSCLC
Teva Pharmaceutical Industries Ltd. - Initial commercialization of Oxycodone 80 mg announced
The Medical Letter - Adverse drug interactions program launched
Thomas Jefferson University - Molecular profiling reveals novel genes linked to glomerular disease
ThromboGenics Ltd. - FDA grants orphan drug designation for microplasmin in pediatric eye surgery
Transoma Medical - $375,000 grant awarded to train employees for medical device market
Trubion Pharmaceuticals, Inc. - Biopharmaceutical company names new senior VP of clinical development
Tulane University - Genetic markers for obesity confirmed
U.S. Centers for Disease Control & Prevention - Mycobacterium tuberculosis cultures may represent cross contamination
U.S. National Cancer Institute - Pheophorbide is specific probe for measuring ABCG2 function and inhibition
U.S. National Institutes of Health - Acute immune response to filarial parasites characterized by Th1 cytokines
Univ. of California, Davis - Trypanosome microtubule-associated protein p15 is vaccine candidate
Univ. of California, Los Angeles - Doctors likely to delay prescribing antiretrovirals for women, minorities
Univ. of Innsbruck Hospital - New anastomosis technique is reliable for vascular anastomosis
Univ. of Rochester Medical Center - Comprehensive study: We know little about environment's effects on kids
Univ. of Rochester Medical Center - Newer drugs more effective at curing strep throat than penicillin
Univ. of Texas, Dallas - Lack of specific brain protein causes marked deficits in learning, memory
University Hospital of Grenoble - New clues for glioma treatment found
University of Aberdeen - Requirements for leukocyte passage across blood-retina barrier described
University of Alabama Hospital - Epidemiology of Aspergillus terreus at university hospital described
University of Alberta - Further studies comparing rehydration therapies would waste resources
University of Barcelona - Trefoil peptide reduces VCAM-1 expression in intestinal inflammation
University of Copenhagen - Dissociation found between insulin resistance and insulin signaling
University of Ferrara - Post-HSCT dendritic cell recovery kinetics determined
University of Florida - Researchers use gel to deliver gene therapy to diaphragm muscle
University of Genoa - CD59 acts as co-receptor in natural killer cell activation
University of Glasgow - Exercise and postprandial lipid metabolism reviewed
University of Homburg - Oral medications are preferred for treating most cases of erectile dysfunction
University of Iowa - Diet rich in lean beef improves serum ferritin levels in adolescents
University of Klinikums Munster - Retrograde ureteropyelography demonstrates fibroepithelioma of left ureter
University of Leipzig - Blood test useful for monitoring immunosuppressant interactions
University of London - Low B12 linked with poor memory in people with high-risk genotype
University of Massachusetts - Haemophilus influenzae protein complex induces cytokine production
University of Michigan - Susceptibility loci for type 2 diabetes found on chromosomes 6, 11, 14A
University of Montpellier - Interaction between mannose receptors and C. albicans clarified
University of North Carolina - BMI superior obesity measure, but pediatricians not using it enough
University of Ottawa - Prevention and genetic testing for breast cancer vary geographically
University of Oviedo - Role of endothelin in inflammatory hyperalgesia in mice described
University of Oxford - Type 2 diabetes onset maps to chromosome 12p and locus on 12q24
University of Pennsylvania - Idiopathic thrombocytopenic purpura therapy reviewed
University of Rome "La Sapienza" - Plant-derived liminoids exhibit potent antiretroviral activity
University of Salerno - NF-kappaB/Rel-mediated apoptosis regulation reviewed
University of Southern California - USC awarded $3.5 million to study DNA enzyme
University of Toronto - New genes linked to gut problems
Valentis, Inc. - Patient enrollment completed for Deltavasc phase II trial
Varian Medical Systems, Inc. - Assets of OpTx Corporation acquired
Vela Pharmaceuticals Inc. - Late-stage molecule licensed for the treatment of depression
Vital Living Corporation - Nutraceuticals company announces increased operating revenue for 2003
Waife & Associates, Inc. - Management consulting company announces new clinical operations associate
Washington University - Combining scans improves radiologists' targeting of lung tumors
Wonkwang University - Liquid chromatography-mass spec used to study antiangiogenic drug in rat model
Wyeth Pharmaceuticals - Four neuroscience compounds to be co-developed and co-commercialized
Xanthus Life Sciences - C-1311 shows preclinical anticancer activity for colon cancer treatment
YM BioSciences Inc. - Drug development company selects chair for breast cancer trial
Yale University - Study suggests managed-care approach may reduce treatment effectiveness
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