Susan Hasty, Publisher
Table of Contents . . . June 4th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Biotech Law Weekly | Other Publications
4SC AG - Agreement signed to develop compounds for autoimmune disorders
Advanced Biotherapy, Inc. - Agreement signed for humanized antibody to interferon-gamma
Cancer Treatment - Oklahoma Cancer treatment bill signed
Chimerix, Inc. - Patent granted for CMX001, an orally-active smallpox therapeutic
Correctional Health - Florida inmates detained under Jimmy Ryce Act sue over treatment
Diomed Holdings, Inc. - Device firm reports 39% increase in revenues
Drug Addiction - Prosecutor says Atlantic City can't start needle exchange program
Drug Benefits - Aetna introduces Medicare-approved drug discount card
Drug Benefits - CMS endorses discount drug card
Health Care - Pharmacy Care Alliance launches Medicare-approved drug discount card
Health Sciences Group, Inc. - U.S. patent granted for cold, flu treatment
Healthcare Access - Rite Aid to accept Medicare Approved Discount Cards
Healthcare Coverage - Medicare drug card fight obscures benefit
LAB21, Inc. - DNA testing delivers first anti-acne therapy for adults
Legal Issues - Judge grants 2-month delay on fen-phen payments
AVI BioPharma, Inc. - Pharmaceutical company reports loss of $0.21 per share
Aarhus University - Personal interviews aid study of binge drinking during pregnancy
Able Laboratories, Inc. - FDA approval granted for Theophylline tablets
Academy Medical Center, Amsterdam - Systemic treatment of esophageal cancer reviewed
Adolor Corporation - First part of NDA submitted for Entereg
Advanced Medical Optics, Inc. - Licensing agreement signed with Quest Vision
Affymax, Inc. - Biotech company expands management team
Aging - Chronic diseases of elderly women limit their locomotor and social activities
American Oriental Bioengineering, Inc. - Soybean protein peptide may inhibit growth of tumor cells
Ankara Oncology Education and Research Hospital - Radiation improves survival in node-positive breast cancer patients
AstraZeneca - Survey: Lack of public awareness about strokes related to AF
Autism Research Center, Cambridge - Too much testosterone blights social skills
Awards - Rising psychiatry researchers receive career development awards
Basel University Hospital - Intranasal influenza vaccine causes facial paralysis
Bayer Pharmaceuticals Corp. - Data: Avelox remains active against bacterial strains
Beth Israel Deaconess Medical Center, Boston - Mouse cardiac surgery techniques described
Breast Cancer - myDNA.com announces publication of breast cancer channel
CV Therapeutics, Inc. - Second phase III trial of Regadenoson initiated
Cancer Research U.K. - Over a third of parents admit sunburn slip despite warnings
Candela Corporation - Device firm reports 29% growth in revenue
Canniesburn Hospital, Glasgow - Potential for adjuvant radiotherapy doesn't sway women from reconstruction
CardioDynamics - Cardiography company acquires Medis
Cel-Sci Corp. - Agreement signed with U.S. Navy for potential malaria drug
Celgene Corp. - Study suggests investigational ADHD drug d-MPH-ER safe and effective in adults
Celgene Corporation - Focalin LA capsules improve ADHD symptoms in adult study patients
Centers for Disease Control & Prevention - Human metapneumovirus infection similar in severity to RSV in children
Centers for Disease Control & Prevention - Maternal malaria and perinatal HIV transmission interaction complicated
Central University of Venezuela - Saliva IgA levels useful for pediatric giardiasis diagnosis
Cepheid, Athens - Circumsporozoite antigens quantified in Plasmodium-infected mosquitoes
Ceregene, Inc. - Plans to further develop Alzheimer disease gene therapy confirmed
Charles University - Insulin resistance not essential component of polycystic ovary syndrome
Chi Mei Fdn. Medical Center, Tainan - Researchers describe the ultrasound features of paratesticular rhabdomyosarcoma
Chinese Academy of Medical Sciences - Telomerase activity reduced in peripheral blood mononuclear cells
Chinese University of Hong Kong - COX-2 correlates with VEGF and angiogenesis in hepatitis B-linked cancer
Chronimed, Inc. - Pharmaceutical distributor reports record revenues
Cleveland Clinic - Retroperitoneoscopic radical nephrectomy successful in super-obese
Cleveland Clinic Foundation - Geographic differences influence prostate cancer mortality rates
Columbia University - Dopamine neurons release transmitter via flickering fusion pore
Cornell University - Immune responses in patients with hepatitis C and HIV described
Crystalplex - Nanobiotech company receives $100,000 investment
Ctr. de Rech. Biomedicales des Cordeliers, Paris - Mechanism underlying MHC II loss in B-cell lymphoma identified
CuraGen Corporation - Drug developer reports $0.36 per share loss
Curative Health Services, Inc. - Infusion drug company completes acquisition of Critical Care Systems
Cytokinetics, Inc. - Small molecule drug developer prices IPO
Dartmouth College School of Medicine - UEC response to bacteria regulate immune protection in female reproductive tract
Denver Health Medical Center - Laboratory diagnosis of urinary tract infections reviewed
Digene Corporation - IARC Recognizes HPV testing as part of cervical cancer screening
Dublin City University - Tummy bug puzzle unraveled
Duke University - GW112 is a novel antiapoptotic protein
Ege University, Izmir - Porokeratosis of Mibelli can be treated effectively with cryosurgery
Eli Lilly and Co. - Alimta showed advances over Taxotere in second-line lung cancer study
Eli Lilly and Company - ADHD study patients fall asleep faster on Strattera versus methylphenidate
Emergency Contraception - Ob/gyn group issues statement on FDA's non-approval of OTC status for Plan B
EntreMed, Inc. - Phase I trial with reformulated Panzem completed
Estacio De Sa University - Fragile X syndrome premutation positively correlates with POF risk
European Institute of Oncology - Clinician diligence makes the difference in managing lymph node metastasis
Ewha Womans University - Caspase-1 mediates Fas-induced apoptosis in human astrocytoma cells
Food Safety - Two macrolide animal antibiotics pose low risk to human health, research shows
Fundacion Instituto de Inmunologia de Colombia - Displacement in 6725 SERA peptide analogue protects against malaria
Genentech, Inc. - Raman spectroscopy useful for structural analysis during formulation development
Genesis Network - Study examines preimplantation genetic diagnosis to reduce multiple births
German Cancer Research Center - Immunotherapy for cancer: Inflammations open up access to tumors
Guilford Pharmaceuticals, Inc. - Andrew R. Jordan steps down as CFO
H. Lee Moffitt Comprehensive Cancer Center - Current developments of immunotherapy in the clinic reviewed
Haemonetics Corp. - Blood-processing company reports increased revenues
Hamamatsu University - Attenuated Listeria harboring plasmids protect against tuberculosis
Harvard Medical School - Patients report high levels of trust in medical specialists
Hemosol Corp. - Biologics company announces closing of reorganization and cash infusion
Hiroshima University - Environmental estrogens direct response elements via different pathways
Horizon Medical Products, Inc. - Medical-products company reports first quarter net sales up 16%
Hospital La Pitie Salpetriere, Paris - Rosuvastatin can correct many atherogenic lipoprotein profiles
Hospital de Ninos Ricardo Gutierrez, Buenos Aires - High viral loads and diverse viremia characterize pediatric HCV infection
Houston VA Medical Center - Research differentiates fibrolamellar carcinoma from hepatocellular carcinoma
Huddinge University Hospital - Anti-obesity drug effect dependent on social status
INFOGEN, Berlin - Achieving - not merely identifying - lipid level goals is critical
INSERM EMI 0335 - Altered bone microenvironment selects for highly aggressive myeloma cells.
Imaging Diagnostic Systems, Inc. - Imaging company granted Canadian patent
Imperial College London - Simple public health measures work best in controlling outbreaks
Imperial College of London - Human T-lymphotropic virus type 1 can spread directly between lymphocytes
Inamed Corp. - Company advances botulinum toxin type A clinical development program
Indiana University - Liver transplant recipients benefit from rabbit antithymocyte therapy
Infertility - Company sponsors toll-free educational and support service for individuals
Ingelheim Pharmaceutical AG - Vestibular defects in head-tilt mice result from mutations in Nox3
International Obesity TaskForce - More than one in four English children overweight
Interpharm Holdings, Inc. - Generics company receives $21 million credit line
Invitrogen Corp. - Company provides two NIH agencies with open access to cloning technologies
Isis Pharmaceuticals, Inc. - Affinitak maker reports decrease in revenues during first quarter
Japanese National Inst. of Environmental Studies - Mice exposed to formaldehyde exhibit different inflammatory responses
Johns Hopkins University - Lysosomal tetraspanin linked to retinal degeneration in genome-wide screen
Kanagawa Children's Medical Center - New genetic mutations discovered in patients suffering from rare disorder
Keimyung University - Diagnosis of breast cancer more difficult in obese Korean women
Keio University - Interferon and sodium butyrate reduce the invasive potential of liver cancer
King Pharmaceuticals, Inc. - Pharmaceutical company reports Q1 revenue drop of 14%; withdraws 2004 guidance
Kitasato University - Rectal carcinoma cells from colitis patients have unique features
Kobe University - Stomach can be considered an endocrine organ
Kochi Medical School Hospital - Cytological and histological diagnostic markers compared
La Sapienza University - IL-15 may be beneficial for AIDS immunotherapy
Laval University - Kainic acid upregulates uncoupling protein-2 mRNA expression in brain
M.D. Anderson Cancer Center - Nonmyeloablative regimens reduce incidence of GVHD better than myeloblative
M.D. Anderson Cancer Center - PTEN transfection sensitizes prostate cancer cells to radiation therapy
Manchester Royal Infirmary - Assay to quantify antibodies to Neisseria meningitidis developed
Massachusetts Institute of Technology - Studies describe how mutations affect BRCA1 function
Max Planck Institute for Infection Biology - DNA vaccine induces protection against intracellular bacterial pathogen
McGill University, Montreal - Antisense inhibitor of methylated DNA-binding protein 2 blocks new tumors
Medco Health Solutions, Inc. - New Jersey selects Medco Medicare-approved prescription discount card
Medical College of Georgia - Mutant Stat5b defines key defective pathway in diabetic mice
Medical College of Georgia - Prevention of type 2 diabetes reviewed
Medical College of Ohio - Moraxella catarrhalis protein is adhesin for human lung cells
Medical College of Wisconsin - Developmental pharmacology principles applied to environmental toxins
Medical University of Gdansk - Peptide MS/MS spectra evaluated with artificial neural network analysis
Medical University of Vienna - Bone marrow VEGF levels parallel the phases of chronic myeloid leukemia
Memorial Sloan-Kettering Cancer Center - New nomograms can predict survival in patients with castrate prostate cancer
Mylan Laboratories, Inc. - NDA submitted for nebivolol
Nanogen, Inc. - Patent issued for electronic devices for active biological operations
National Cardiovascular Center, Osaka - Novel transcription regulator protein p60TRP characterized
National Yang Ming University - Guillain-Barre coexists with pericarditis after influenza vaccination
Nellcor - Oklahoma Children's Hospital adopts oximetry systems
Neurogen Corp. - Drug-discovery company reports on portfolio, announces lower first quarter net losses
NeurogesX, Inc. - One-hour application of NGX-4010 patch results in sustained pain reduction
New Cross Hospital, Woverhampton - Combined image guidance can be done with reduced biopsy weights
Northwestern University - FGF2 signaling determines beta-catenin effect on neural stem cell proliferation
Novavax, Inc. - Vaccine maker reports 170% increase in total revenues during first quarter
Obihiro Univ. of Agriculture & Veterinary Medicine - Antigens of abnormal isoform of prion protein characterized
Onyx Pharmaceuticals, Inc. - Cancer-focused company reports lower first quarter net losses
Pennsylvania State University - Ambient pollutants may impair cardiac autonomic control
Penwest Pharmaceuticals Co. - Additional data needed to support Oxymorphone ER New Drug Application
Pharmaceutical Resources, Inc. - Par Pharmaceutical begins shipment of generic Glucovance tablets
Pharmessen Scientific, Inc. - Pharmaceutical company completes $300,000 equity placement
Pheromone Sciences Corp. - Healthwatchsystems acquires marketing rights to Fertilite-OV fertility monitor
Presbyterian Univ. Hospital, Pittsburgh - BK virus load correlates with clinical course of infection in renal transplants
Procter & Gamble Pharmaceuticals - Study: Testosterone patch improves desire in surgically menopausal women
Progen Industries Limited - FDA grants Orphan Drug Status to PI-88 for treatment of melanoma
Psychiatry - Majority of surveyed psychiatrists use PDAs more than four times a day
Qiagen N.V. - Netherlands holding company reports increase in first quarter net sales
Quality Assurance - Triosyn T-1000 respirator receives NIOSH certification
Queen's University Belfast - Endocrine profile normal in children with Perthes disease
RadNet Management, Inc. - MIC signs agreement with imaging provider in California
Ricardo Gutierrez Children Hospital - P6 protein intranasal vaccine protects against Haemophilus influenzae
Rigel Pharmaceuticals, Inc. - Pharmaceutical company announces first quarter 2004 financial results
Royal Free & Univ. College Medical School, London - Genetic testing for cardiovascular disease risk may not be helpful
Royal Perth Hospital - HLA-B*5701 and Hsp70-Hom M493T alleles necessary for abacavir hypersensitivity
Russian Academy of Medical Sciences - Laser destroys vascular plaques
SUNY Stony Brook - Mesenchymal stem cells make cardiac connexins and form functional gap junctions
SUNY Stony Brook - Pro-nucleotide inhibitors of adenylyl cyclases potentially therapeutic
Sangamo BioSciences, Inc. - $2M Advanced Technology Program grant awarded for ZFP TF technology research
Scripps Research Institute - Scientists publish novel findings about neovessel formation
Sepracor Inc. - Experimental drug improves sleep in older patients
Serono, Inc. - Zorbtive launched for treatment of short bowel syndrome
Sher Institutes for Reproductive Medicine - New test determines pregnancy potential of embryo before IVF implantation
Sirna Therapeutics, Inc. - Therapeutics developer closes on $18.7M private placement financing
Stanford University - Electro-osmotic flow shows promise for use in neural interfaces
Stanford University - Hematopoietic stem cells adopt mature hematopoietic fates in ischemic myocardium
State University of New York Upstate Medical Unive - Ca2+ and CaM kinase regulate neurofilament expression
State University of New York, Albany - Cyclin-dependent kinase 2 activated by cyclin E in breast cancer cells
State University of New York, Buffalo - Central obesity increases risk for elevated liver enzymes and disease
State University of New York, Buffalo - Glucose and alcohol exert different effects on reactive oxygen species
Syrrx Inc. - Grant to enable study of crystallization processes of membrane-associated proteins
Tanox, Inc. - TNX-355 phase II clinical trial initiated for treatment of HIV
Technion Israel Institute of Technology - Modification of BCR tonic signals activates receptor editing in immature B cells
Technion-Israel Institute of Technology - Protein substrates of N-terminal ubiquitination reported
Tercica, Inc. - Biopharmaceutical company reports first quarter financial results
Teva Pharmaceutical Industries - Copaxone study shows effectiveness in primary progressive MS
Tokai University - Components of acellular pertussis vaccines in Japan verified
TriPath Imaging, Inc. - Diagnostics company announces 39% increase in first quarter revenues
TriVirix Inc. - Manufacturing agreement announced for PC card blood pressure meter
Tufts Health Plan - Home monitoring program offers new support for heart failure patients
U.S. Food & Drug Administration - CpG oligodeoxynucleotides find immunotherapeutic use
U.S. National Institutes of Health - Animal studies show promise treating severe chronic pain
U.S. National Institutes of Health - Presence of certain eye disorders linked with poorer survival rates
U.S. National Institutes of Health - X-ray analysis conducted on protein vaccine candidate for malaria
U.S. Veterans Affairs Department - VA to close three hospitals
UNESP - Bothrops jararaca venom targets tumor cells and their mediators
Univ. of California, San Diego - Questionnaire and potassium sensitivity test enable quick diagnosis
Univ. of California, San Francisco - "Cardiofunk" mutation probable source of valve problems
Univ. of California, San Francisco - The continuum of hepatitis C-related fibrosis grows with alcohol intake
Univ. of Michigan Health System - Breast exams could be 'teachable moment' to prompt colon cancer screening
Univ. of Wisconsin, Madison - Wisconsin chemists find a new chink in TB's armor
Universita Cattolica del Sacro Cuore, Rome - Deep salvage with amprenavir and lopinavir/ritonavir partially effective
Universitat de les Illes Balears - Uncoupling proteins are gender dependent and affect weight control
Universite Victor Segalen Bordeaux 2 - Translational repression mediated by the GM-CSF AU-rich element
University Children's Hospital, Brussels - Neuropeptides VIP and PACAP interact with leukemic myeloid cells
University of Alberta - Rituximab rapidly effective for patients with cold and warm autoantibodies
University of Bari - Early HITT diagnosis crucial for Lepirudin efficacy
University of Bologna - Hamster model for Chlamydia pneumoniae infection developed
University of California - Urban homeless often battle chronic lung disease
University of California, Davis - Isoflavone compound may benefit men
University of Cambridge - Chemokines and cytokines expressed in Salmonella-infected chicken hatchlings
University of Cambridge - Murine herpesvirus-68 ORF73 critical for latency establishment and maintenance
University of Frankfurt - Valproic acid modulates the synthesis of angiogenic proteins in cancer cells
University of Fribourg - In vivo gene delivery with regulatable lentivirus surveys neurogenic function
University of Goteborg - Staphylococcal protease does not affect outcome of infectious arthritis
University of Heidelberg - Gefitinib and trastuzumab show promise for treatment of metastatic breast cancer
University of Helsinki - Effects of imipramine on prefrontal cortex gene expression elucidated
University of Illinois - T. brucei genes encode functional PMCAs essential for Ca2+ homeostasis
University of Illinois - Role of conserved acidic residue in LDL-A determined
University of London - Novel C. rodentium type III secreted proteins reduce colon hyperplasia
University of Manchester - Direct cell contact influences fate of bone marrow mesenchymal stem cells
University of Maryland - Fes regulates myeloid differentiation via transcription factors
University of Massachusetts - Thymic Notch1 activation regulated by p53
University of Miami - Some melanoma cells use the abluminal surface of vessels for migration
University of Michigan - Regulation of luteinizing hormone receptor expression reviewed
University of Naples - Cognitive impairment is common in older patients with congestive heart failure
University of Nebraska - Aromatase inhibitors for postmenopausal breast cancer therapy reviewed
University of North Carolina - Study may help predict premature infants at risk of total blindness
University of Oxford - MRI represents food texture and oral fat in the human brain
University of Oxford - Response to conserved epitope linked to protection from malaria
University of Paris 11 - Hepatocellular carcinomas present newly identified characteristics
University of Pittsburgh - Prostate-specific antigen doubling time is useful in finding recurrent disease
University of S. Florida - A heme oxygenase-1 plasmid system protects the heart from ischemic injury
University of Uppsala - Oral diphtheria vaccine with microparticle adjuvant is immunogenic
University of Warwick - Fat-fighting undermined by over active eating pacemaker
University of York - E-Health is no threat to GPs
University of the West of England - Nociceptin/orphanin FQ modulates T-cell activity
Vicuron Pharmaceutical - Novel inhibitors of bacterial RNA polymerase I characterized
Virginia Polytechnic Institute - Weight loss is critical to effective management of obesity hypertension
ViroLogic, Inc. - Biotechnology company reports 29% increase in first quarter revenue
Wageningen University - Leptin responsiveness not affected by variation in leptin receptor gene
Wake Forest University - Monkey study suggests ET may lower androgens in postmenopausal women
Warsaw School of Medicine - Serum growth factor activity characterized in hemodialysis patients
Yale University - Ethanol post-fixation enhances histological bone analyses
Yale University - Losing a job near retirement age significantly increases risk of stroke
Yale University - Night-time eating in adults with binge eating disorder described
Yamaguchi University School of Medicine - Future savings offset the initial costs of treating chronic hepatitis C
Zambon Group - Newron inks agreement to develop novel treatments for pain conditions
iCAD, Inc. - CAD products manufacturer reports 145% increase in first quarter sales
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