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Biotech Law Weekly

Susan Hasty, Publisher

Table of Contents . . . June 18th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Law Weekly | Other Publications

Abbott Laboratories - Medicine price hike highlights controversy of government funding drug research

BTG - Novel technique brings prenatal testing from maternal blood closer to reality

CytRx Corporation - Use of breakthrough target demonstrated to regulate obesity licensed

Healthcare Coverage - Retirees fear drug benefit cuts, pushing them into costlier Medicare plans

Illegal Drugs - Lake Charles man pleads guilty to selling unapproved drugs

Legal Issues - Aetna withdrawing lawsuit against Abbott over AIDS drug

Locus Pharmaceuticals - Broad U.S. patent issued for computational drug design technology

Mental Health - Arkansas to end program, send mentally ill acquitted of crimes for private treatment

Nutra Pharma Corp. - ReceptoPharm completes first step in production of RPI-78M.

Pharmaceutical Care Management Association - Law would increase drug costs for consumers, employers, pharmacy group says

Prescription Drugs - Stolen drugs weren't generic OxyContin

Senetek PLC - Healthcare technologies company announces profitable first quarter

Spectrum Pharmaceuticals, Inc. - Pharmaceutical company reports net loss for first quarter

Buck Institute for Age Research - Caspase-2 involved in selective neuronal cell death in HD in striatum and cortex

Univ. of Arkansas for Medical Sciences - Myeloablation and autotransplant reverses renal failure in myeloma patients

University of Rome La Sapienza - Intravesical gemcitabine in superficial bladder cancer is well tolerated

Aarhus University Hospital - AICAR stimulates adiponectin and inhibits cytokines in adipose tissue

Abbott Laboratories - Positive results reported on trials of Humira in Crohn disease

Abiomed, Inc. - AbioCor implant patient removed from life support due to liver, kidney failure

Academy Sinica - In vivo electroporation increases efficacy of encephalitis vaccine

Accelr8 Technology Corp. - New president named at diagnostics firm, divestiture announced

Aichi Cancer Center - Long-term outcomes of radiotherapy for cervical cancer reported

American Medical Association - Group comments on new report rejecting link between vaccines and autism

American Medical Systems - Penile prosthesis infection rates decrease with InhibiZone use, study shows

American Oriental Bioengineering - Chinese biotech firm reports income of $0.04 per share

Angiotech Pharmaceuticals, Inc. - Canadian pharmaceutical firm nominates new member to board

Antares Pharma, Inc. - Pharmaceutical company reports 20% decrease in revenues

Arysta LifeScience Corporation - Japanese life sciences firm names new CEO

Axya Medical, Inc. - Device firm names Ronald L. Greene as VP, sales and marketing

Barrier Therapeutics, Inc. - Marketing authorization granted for Zimycan from Belgian health authority

Bausch & Lomb - FDA approval granted to make, sell generic anti-infective drug

Bayer HealthCare, L.L.C. - Clinical trial investigates treatment of neurological disorder Gamunex

Baylor College of Medicine - NIH awards Baylor, Texas Children's No. 1 spot in research funding

Baylor University Medical Center - Trial data of hepatitis C patients after liver transplantation presented

Benitec, Ltd. - Hepatitis drug maker acquired

BioCurex, Inc. - Results from European study show strong RECAF expression by cancer cells

BioSante Pharmaceuticals - Hormone therapy developer reports loss of $0.17 per share

Biophan Technologies, Inc. - Breakthrough attributes of biothermal battery highlighted

Birmingham Women's Healthcare, NHS Trust - Multidisciplinary team working needs continual evaluation

Boston Biomedica, Inc. - Biotech, diagnostics services company reports 1.6% decrease in revenue

British Society for Pediatric Endocrinology - Type 2 diabetes among U.K. Asian children higher than among white children

C.R. Bard - Mentor licenses patent covering method for treating urinary incontinence

CHUQ, Quebec City - Denatured collagen used as support for FGF-2 delivery system

CNRS, Nogent Sur Marne - Self-renewal capacity is a widespread property of neural crest precursor cells

CSIC, Madrid - Z-DNA is a new in situ marker for transcription

Cardinal Health, Inc. - Medical device firm acquired for $2 billion

CardioMag Imaging - Cardiac diagnostics company announces election of new director

Catholic University of Korea - Amantadine did not affect weight gain induced by olanzapine

Catholic University of Korea - Recombinant adenovirus p53 effects cancer cell apoptosis

Children's Hospital of Michigan - Linezolid effective against VREF in premature infant

Children's Oncology Group, Arcadia - RAS mutation status is not linked to acute lymphoblastic leukemia outcomes

Chinese Academy of Sciences - Electron holography facilitates study of MTJ microstructure

Chiron Corporation - Phase III Trial for Tifacogin initiated

Columbia Univ. Mailman School of Public Health - An aspirin a day may keep breast cancer away

Council for Affordable Quality Healthcare - Less than half of heart attack survivors take beta-blockers after first year

Creighton University - A new anthocyanin-rich berry extract suppresses cancer growth mechanisms

Cryolife - FDA sets new rules on who can donate human tissue

Cynosure, Inc. - Pharmaceutical firms collaborate in trial of dermatology product

Cypress Bioscience, Inc. - Bioscience company added to Nasdaq biotechnology Index

DOV Pharmaceutical, Inc. - Pharmaceutical company added to NASDAQ Biotech Index

Drug Costs - Michigan insurer shows generic drugs reduce expenditures by $97M

Duke University - Insight into transplant rejection might lead to novel prevention therapies

Eastman Kodak Co. - Fischer Imaging to offer PACS and VIParchive technology

Elan Corp., plc - Inex makes milestone payment

Emory University - Combination of drug therapies reduces cocaine use in primates

Emory University - Toll-like receptor 2 ligand stimulates Th2 responses in vivo

Estadual Paulista University, Sao Paulo - DNA damage is found in gastric mucosa of patients with Helicobacter pylori

Federal University of Minas Gerais - Tumors stimulate cytokines that trump distant repair mechanisms

Federal University of Parana - Structure is key to the antitumor properties of 1,3,4-thiadiazolium mesoionics

FoBiG GmbH - Common dye products used in textile can be mutagenic

GOCS, Neuquen - Trimetrexate and leucovorin modulate 5-FU in advanced colon cancer patients

Genetronics Biomedical Corp. - EPT-focused company closes $10.90 million preferred stock financing

Genome Quebec - GenoMed signs genotyping contract with Genome Quebec

Geron Corp. - Data published describing genes linked to growth and differentiation of hESCs

Guidant Corp. - Research evaluates heart failure treatments for landmark study

Haartman Institute, Helsinki - No link between anti-pneumonia antibodies and asthma

Hacettepe University, Ankara - Mitomycin-C-loaded alginate carriers created for bladder cancer chemotherapy

Halsey Drug Co., Inc. - Drug company completes restructuring, reports net income of $680,000

Harvard Medical School - Immune cells may play important role in progression of diabetes

Harvard University - VEGF-A uses macrophages to generate new lymph and blood vessel growth

Helsinki University Central Hospital - Ospemifene effective in reducing bone turnover in postmenopausal women

Hope Hospital, Manchester - Synthetic ligament prosthetic effective for recurrent THA dislocation

Hoshi University - Reduced opioid sensitivity under neuropathic pain-like state elucidated

Hospital Infantil Mexico Federico Gomez SS - MMPs secreted by explants of lesions of uterine cervix

Human Proteome Organisation - HBPP selects ProteinScape software

Immunomedics, Inc. - Company reports first clinical results with epratuzumab in lupus

Integrated Genomics, Inc. - Bioinformatics company adds personnel in business development and marketing

Interpharm Holdings, Inc. - Generics company reports increased revenue

Introgen Therapeutics, Inc. - New data support utility of oncolytic viruses in the treatment of cancer

Joint Implant Surgery Inc. - Cementless total hip arthroplasty feasible for elderly patients

Karolinska Institute - Proteolytic processing is critical to angiogenic suppression

Karolinska Institute - Tamoxifen and peptide collaborators antagonize estrogen receptivity

King's College London - Vitamin E location in membranes suggests functions beyond anti-oxidant

Kuopio University - Training effect on heart rate and blood pressure variability examined

Kyoto Prefectural University - Sodium gluconate protects animal models from large bowel cancer

Kyoto University - Cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells

Kyushu University - Bone marrow mononuclear cells limit myocardial infarct size by VEGF induction

Laboratory Fisiopatol. Renal, Sao Paulo - COX-2 inhibition and AT1 R blockade treatment for chronic nephropathy

Legal Issues - Animal-rights activists charged in actions against testing lab in New Jersey

London School of Hygiene and Tropical Medicine - GPs' beliefs about patients influence treatment

Loyola University - IL-6 provokes a gene linked to systemic lupus erythematosus susceptibility

MRI Devices Corp. - Intermagnetics to acquire maker of RF coils

Massachusetts Inst. of Technology - Chromosome segregation and genomic stability may be related to tumorigenesis

Mayo Clinic - HLA-DQ/DR double transgenic mice are valuable as RA model

Mersin University - Glutathione S-transferase gene polymorphism increases risk of CAD in smokers

Microbia, Inc. - Company presents preclinical data on IBS drug candidate

Middlemore Hospital, Auckland - Suction dressings useful for immobilizing dermal substitute

Motion DNA Corp. - Diagnostics company enters strategic agreement with Physicians On-Call

Nabi Biopharmaceuticals - Thomas H. McLain named chairman of the board of StaphVAX maker

Nanjing University - Interaction of serum albumin with novel antidiabetic agent described

Nat. Inst. of Public Hlth & the Env., Bilthoven - Number of infectious measles viruses in vaccines estimated by PCR

Natl. Inst. Advanced Ind. Science & Tech., Ibaraki - Expressions of inhibitory Smads differentially regulated by TPA

Neurochem, Inc. - Neuroscience drug development firm emphasizes progress in clinical pipeline

New York Presbyterian Hospital - Laparoscopic liver resection is safe and feasible

North Shore LIJ Research Institute - Patients with chronic lymphocytic leukemia host unique antigen receptors

Northwestern University - Researchers target estrogen to kill cancer but not the patient

Norwegian Radium Hospital - UV-induced intermediate stage oxidative stress maintains genomic instability

Nu Skin Enterprises, Inc. - Allen Andersen named to board of supplement/personal care company

Obesity - StayWell Weight Management Solution Center launched

Osaka Chuo Hospital - Hepatoma-derived growth factor encourages lung remodeling after injury

Osaka University - Molecular WT1 assay useful for minimal residual disease monitoring

PediaMed Pharmaceuticals, Inc. - Pharmaceutical company appoints chief medical officer

Pennsylvania State University - Study suggests double punch could more efficiently kill viruses

Peter MacCallum Cancer Institute - PET and conventional images of small-cell lung cancers are often discordant

Presidency College, West Bengal - Arsenic trioxide generates islet cell toxicity in rabbits

Proxima Therapeutics, Inc. - MammoSite boost radiation delivery shows promise in breast cancer study

Regional Cancer Center, Kerala - p53 over-expression correlates with local treatment failure in oral carcinoma

Reproductive Biology - Protein expression studied in monkey endometrium

Research Center Borstel - Various immune modulatory molecules induced in CD34+ hematopoietic cells

Rhein Westfal TH Aachen Clinical Center - Gene induction eliminates fibrogenic stellate cells in the liver

Rush Presbyterian St. Luke's Medical Center - Diabetics benefit from aggressive blood pressure control

Russian Ministry of Health - Anti-GM3 synthase antibody enables immunodetection in human tissue

SARS - New method may detect virus in minutes

San Giovanni Antica Sede Hospital - Concomitant docetaxel, carboplatin, and radiotherapy treat head and neck cancer

Scimagix Inc. - Scientific Image Management System enhanced with new management, reporting tools

Shanghai Jiao Tong University - Uracil-DNA glycosylase of Chlamydia pneumoniae characterized

Shaw Environmental Inc. - Novel assay provides improved measure of haloacetic acids in drinking water

Solvay Pharmaceuticals - IBS-D study patients experience relief of pain, discomfort with cilansetron

Source Medical Corp. - MedMira signs Canadian distributor to market Rapid HIV Test Kits

St. Jude Children's Hospital, Memphis - LAG-3 regulates T-cell expansion after antigen activation

St. Jude Children's Research Hospital - Study looks at marrow stem cells and chemotherapy

Stanford University - Regulatory role of Blimp-1 clarified

Stanford University - Researchers explore gene treatment to obliterate HIV before it does damage

Swiss Federal Inst. of Technology - Exposure of phosphatidylserine is not a primary signal for RBC removal

Technion-Israel Institute of Technology - Clues to acquired renal failure discovered in rare childhood disease

Tel Aviv University - New chemical adaptor unit releases a drug by enzymatic triggering

Tokyo Women's Medical University - Hemofiltration may trap and destroy hepatitis C virus particles

U.S. Centers for Disease Control & Prevention - Aging Americans and diabetes reviewed

U.S. National Cancer Institute - Progesterone receptor deficient in chromatin binding has altered cellular state

U.S. National Institutes of Health - Apoptosis increases efficacy of alphaviral replicase-based DNA vaccines

U.S. National Institutes of Health - More than one-third of U.S. adults use alternative therapies

U.S. Preventive Services Task Force - Check children under 5 early for vision problems

Umea University - Unexpected similarities between raindrops and proteins

United Therapeutics Corporation - Remodulin approved in Australia for treatment of pulmonary arterial hypertension

Univ. of Illinois, Urbana-Champaign - Dietary protein impact on glycemic control during weight loss reviewed

Univ. of Medicine & Dentistry New Jersey - Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death

University 'Roma Tre' - S-palmitoylation modulates human estrogen receptor-alpha functions

University Hospital Hamburg-Eppendorf - Environmental pollution may increase twin birth rates

University at Buffalo - Very-low-fat diet decreases "good cholesterol," does not improve heart health

University of Aberdeen - IL-1 genotype may determine clinical outcome of H. pylori infection

University of Alabama, Birmingham - 15q26.1-26.2 is candidate locus for congenital diaphragmatic hernia

University of Alabama, Birmingham - Higher mortality among African Americans not likely due to healthcare access

University of Birmingham - Parental cigarette smoking increases children's risks of hepatoblastoma

University of California, Davis - New scintigraphy test could aid preoperative assessment of liver function

University of California, Irvine - Harmful fungal exposure not determined by blood test alone

University of California, Riverside - Novel microelectrode array can isolate individual neurons

University of California, San Francisco - "Noisy" genes can have big impact

University of Cincinnati - Women believe physicians should screen patients for intimate partner violence

University of Colorado - Rotating camera puts fresh spin on coronary angiography

University of Edinburgh - Antigen-loaded CD40-deficient dendritic cells mimic antigen delivery

University of Florence - Endogenous VEGF-A controls how MCP-1 affects vascular smooth muscle cells

University of Florence - Full-length dystrophin associated with gastric ICC ultrastructural modifications

University of Glasgow - Squalestatin cures prion-infected neurons

University of Iowa - Adeno-associated virus vectors correct single base pair mutations

University of Iowa - Study said worms may help bowel disorders

University of Louvain, Brussels - Cxcr4 receptor may exert trophic influences on precursor cell proliferation

University of Manchester - Risk derived from use of antibiotic soaps questioned

University of Miami School of Medicine - Once-daily Valcyte prevents CMV after kidney transplant in study

University of Munich - Nerve tissue protein S100 levels identify high-risk patients

University of Nebraska - Lung cells give rise to lymphohematopoietic cells in irradiated animals

University of Paris 06 - Efavirenz induces strong inhibition of SREBP-1c-dependent lipogenic pathway

University of Pennsylvania - CD25+ CD4 cells have a distinct IL-2R signaling pattern

University of Pittsburgh - Simplified method for determining rosiglitazone in plasma developed

University of Poona -  Asparagus racemosus extract shows potential as vaccine adjuvant

University of Rochester - Erased androgen receptor activity could staunch prostate cancer progression

University of Rome - Pathogenesis of keratoconjunctivitis is probably multifactorial

University of Santiago de Compostela - Rapid fluorimetric microplate assay detects seafood toxins

University of Tokyo - Portal vein embolization can increase the safety of hepatic resection

University of Toronto - Cooperative pre-TCR and Notch signaling crucial for thymocyte maturation

University of Turin - Platelet cyclic 3', 5'-guanosine monophosphate inversely correlates with age

University of Valencia - Bcl-6 mutation status marks early-stage B-cell chronic lymphocytic leukemia

University of Virginia - Good news for red wine drinkers: Protein in grape skins can kill cancer cells

University of Washington - Evidence found for fusion between cardiac and skeletal muscle cells

University of Washington - Fluorescent labelling method facilitates 3-D imaging of cochlear tissues

University of Wroclaw - Dimerization of HLA-DR peptide fragment enhances immunosuppression

VA Greater Los Angeles Healthcare System - Prevalence and severity of anemia increases with advancing HIV disease

VIASYS Healthcare Inc. - Inhaled nitric oxide gas and gas delivery devices lawsuit settled

Vajira Hospital, Bankok - The accuracy of frozen section in diagnosis of ovarian masses is generally good

Vasamed - Technology development company acquires Impedance Cardiography technology

Veterans Army Hospital, Athens - Painless suction drain removal technique developed

Vicuron Pharmaceutical, Varese - Dalbavancin effective against methicillin-resistant Staphylococcus aureus

Vital Living Inc. - Nutraceutical/pharmaceutical developer reports 291% increase in revenues

Washington University - Severity of other illnesses can help predict outcomes for cancer patients

Weizmann Institute of Science - Autophagy is a newly recognized tumor suppressor modality

Wonkwang University - Pv30 antigen suitable for serodiagnosis of malaria in Korea

Wyeth Pharmaceuticals - Physician finds promise in study of novel injectable antibiotic

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