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Biotech Law Weekly

Susan Hasty, Publisher

Table of Contents . . . July 23rd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Law Weekly | Other Publications

Alaris Medical Systems - ICU Medical announces court order in patent infringement lawsuit

Biosystemix - Data mining, predictive modeling provided for personalized medicine models

CDEX - Alpha test of ValiMed impaired clinician solution initiated

CyDex, Inc. - Hovione enters drug-development alliance for potential new products

Ethicon Endo-Surgery, Inc. - Inamed Corp. reaches settlement of patent litigation over gastric banding

Genetronics Biomedical Corp. - Two patents awarded for applications of electroporation therapy

Georgia Reproductive Specialists - Human oocyte cryopreservation is an alternative to embryo cryopreservation

Healthcare Coverage - Plenaxis assigned Medicare permanent billing code for hospital use

Legal Issues - Three in Rite Aid scandal begin prison terms

Medicare/Medicaid - Mississippi governor extends Medicaid/Medicare switch deadline

National Geriatric Psychiatry Association - Group lauds law that would address geriatric mental health

Pain Medicine - Hospitals seek to spare children's pain

Prescription Fraud - Nebraska state senator arrested, accused of prescription fraud

Shandong University - Vein grafts remain patent following adenovirus-mediated gene delivery

U.S. Centers for Medicare & Medicaid Svcs. - Medicare boosts payments for ambulance transportation

Ludwig-Maximilians University, Munich - Trastuzumab combined with epirubicin and cyclophosphamide is safe for the heart

Aarhus University - TARTAR dimer therapeutic target for treatment of HIV-1 infection

Academia Sinica - Activity of analogs of influenza hemagglutinin fusion peptide described

Accumetrics, Inc. - Diagnostics company announces $13.5M financing

Affymetrix, Inc. - Immusol initiates collaboration to advance oncology drug-discovery efforts

Ajou University - Genistein may be an alternative to estrogen for treatment of AD

Alzheimer Disease - Alzheimer Association seeks annual $1B federal investment for research

American Health Care Association - Group claims billions in Medicaid funding lost from phase-out of fiscal relief

American Pharmaceutical Partners, Inc. - FDA grants approval for dimenhydrinate injection

Amgen Inc. - Neulasta lowers infection rate in myelosuppresive chemotherapy study patients

Amgen, Inc. - Biologics License Application submitted for FDA approval of Palifermin

Amrad - Australian anti-infectives business to be demerged

Analogic Corp. - Halifax Medical Center selects VERICIS from Camtronics

Arthritis - PA Health Department presents "State of Arthritis in Pennsylvania" report

ArthroCare Corp. - Coblation tonsillectomy offers more benefits than electrocautery, study shows

Association of the British Pharmaceutical Industry - New body will boost clinical trials in U.K., says industry group

Auxeris Therapeutics Inc. - Biopharmaceutical company names new chief scientific officer

Awards - PacifiCare receives National Exemplary Practice Award for diabetes program

Baystate Medical Center - Benefits of oral contraceptives far outweigh potential risks

Bentley Pharmaceuticals, Inc. - Approval granted to market generic versions of lansoprazole in Spain

BioSante Pharmaceuticals, Inc. - Phase II trial for LibiGel completed

Bridge Fertility Center, London - Chromosomal chaos in early development linked to abnormalities in cytokinesis

Cancer - Former cancer patient debuts cancer-fighting video game

Cancer Mortality - CDC: More people with cancer surviving

Cancer Therapy - NCI selects SRI to qualify cancer drug candidates for clinical studies

Cancer Treatment - Ocala Oncology inks agreement with Shands HealthCare, UF Health Science Center

Case Western Reserve University - Insulin under amyloidogenic conditions indicates protein-folding

Cedars Sinai Medical Center - Glioma tropic neural stem cells consist of astrocytic precursors

CellExSys, Inc. - Merger agreement with Chromos announced

Children's Hospital, Boston - Cutaneous immune sensitization is enhanced by antigen-independent IgE effects

Chiron Corporation - Nonexclusive HCV license granted to Prosetta

City Hospital Triemli, Zurich - Proton radiography can monitor patients who undergo proton radiotherapy

Cold Spring Harbor Laboratory - Microarray detection of transcription factor-binding motifs enhanced

College of New Jersey - Women with family history of breast/ovarian cancer find support in friends

Colorado Center for Reproductive Medicine - High protein diet may be bad for women trying to conceive

Corixa Corporation - Bacterial flagellin is dominant antigen in Crohn disease

CuraGen Corporation - Preclinical data presented on CG53135

CytRx Corporation - Alexander Cappello retires from board of directors at biotech company

DOBI Medical International, Inc. - Sales distribution agreement signed for the ComfortScan in India

DayMoon Scitech, Inc. - HemoGenix launches HALO hemotoxicity test platform in Korea

DePuy Mitek, Inc. - Bio-Intrafix launched for ACL repair

Durect Corporation - Agreement signed to develop treatments for inner ear disorders

EORTC Data Center - Quality-of-life data predict the survival of metastatic breast cancer patients

Emphasys Medical, Inc. - Device firm closes oversubscribed $27.5M round of private financing

Eyetech Pharmaceuticals, Inc. - Ophthalmology company names Michael J. Regan to the board of directors

Finance - Vantage Oncology, Inc., raises $15 million in Series B financing

Fundacion Valenciana de Investigaciones Biomedicas - Transcription factor essential in promoting Tomm70 gene expression

GPC Biotech, AG - New patent issued for cell-cycle inhibitor "composition of matter"

Gentiae Clinical Research, Inc. - LifeSignals platform to include Enterprise ECG data warehousing solution

Health Canada - Researchers identify occupational exposures that increase NHL risk

Healthnostics, Inc. - H-Quotient announces major software sale and listing change

Heart Research Institute, Sydney - Raising HDL levels may increase longevity

INRA - Phage protein confers resistance to lactococcal abortive mechanism

Icagen, Inc. - Ion-channel-target focused company taps Mark J. Suto, PhD

Iconix Pharmaceuticals, Inc. - ICOS enters chemogenomics collaboration

Imperial College, London - HIV-1 immune response differs in exposed seronegative and seropositive partners

Influenza - 100 million doses of flu shots to be available

Information Technology - Thomson PDR and ZixCorp to enhance ePrescribing solution

InnaPhase Corporation - Newton LIMS selected for quality control manufacturing facility in Spain

Innsbruck University - Interleukin-6 stimulates VEGF autocrine loops in prostate cancer cells

Institute Butantan - Kininogen inhibits metalloproteinases of Bothrops jararaca venom

Institute Jean Godinoi, Reims -  Chlamydia pneumoniae infection is unrelated to squamous cell carcinoma

International Agency for Research on Cancer - Plasma tests for Ser-249 TP53 mutations disclose liver cancer status

International Diabetes Federation - Diabetes and obesity epidemic in children spurs international call to action

Intradigm Corp. - SARS Coronavirus siRNA inhibitors achieve prophylactic and therapeutic effects

Johns Hopkins University - The HMG-I oncogene is overexpressed in human leukemia

Karolinska Hospital - MMP-13 is androgen-regulated in prostate cancer

King Faisal Specialist Hospital & Research Centre - Mixture modeling can improve quality of DNA microarray data

Kitasato University - Novel allogeneic cultured dermal substitute system shows promise

Kongsvinger Hospital - Floride and bisphosphonates make a nice cocktail for the bones

Kyoto University - Differentially expressed molecules in adult T-cell leukemia cells identified

Kyung Hee University - Exercise suppresses NPY in hypothalamus of food-deprived rats

Life Force International - Survey: Consumers confused about the right combination of supplements

Liquent, Inc. - Company unveils product registration, submission lifecycle-management solutions

Mayo Clinic - Cardiac xenotransplantation may be feasible in the future

Medical College of Wisconsin - EBMT Risk Score for CML patients receiving stem cell transplants is validated

Medidata Solutions - Company launches unified platform for eCDM: RAVE 5.0

Merix Bioscience, Inc. - Companies to develop personalized dendritic-cell vaccines

MicroIslet, Inc. - Islet-cell transplantation studies in primates to be conducted at UC Davis

Misys Healthcare Systems - Laboratory-Collection Manager launched to enhance specimen-collection accuracy

National Cancer Center, Japan - Eating patterns in Japan predict risks for women, men

National Inst. for Medical Research, London - Role of ICOS signaling elucidated

Natl. Defense Medical College, Tokorozawa - FISH analysis of p53 and chromosome 17 has limited prognostic value

Nerima Hikarigaoka Nihon Univ. Hospital - GRAP gene may be involved in Sjogren syndrome pathogenesis

New York University - Controversies in laparoscopic adjustable gastric banding outlined

Nippon Medical College, Tokyo - Severe head injury can cause cardiopulmonary disturbance

North Shore Univ.-Long Island Jewish Hlth. System - Improved pediatric cranioplasty technique developed

NuVasive, Inc. - Spine-focused company underwriters exercise over-allotment option

Nutrition - Some healthy eaters say they are hefty

Ohio State University - Tyrosine phosphorylated disabled 1 recruits Crk family adapter proteins

Okayama University - Stimulated CD40 ligand stops mantle cell lymphoma proliferation

Oregon Health & Science University - Tuberculosis immunology in children reviewed

Osaka University - ABCG2 positive limbal epithelial cells putative corneal epithelial stem cells

Osaka University - Electrogastrography helps determine pathophysiology of eating disorders

Oxford University - Genetic basis for metabolic diseases detected

Partners AIDS Research Center, Cambridge - Antigen-specific T cells migrate away from CXCR4-binding HIV-1 gp120

Paterson Institute of Cancer Research - Adoptive transfer of anti-idiotypic T cells cure B cell lymphoma

Pennsylvania State University - Childhood sports involvement predicts participation in sports as adult

Personnel - Martha Schram named president of Aegis Therapies, SVP of Beverly Enterprises

Planar Systems, Inc. - FDA approves marketing of flat-panel DomeC5i system for mammograms

Pontificia University of Catolica Chile - Large pathogenicity island in Salmonella enterica excised

Pro-Pharmaceuticals, Inc. - Davanat with 5-FU well tolerated in study patients with advanced solid tumors

Purdue University - Artificial sweetener may disrupt body's ability to count calories

Queensland Institute of Medical Research - CLAG 9 is located in rhoptries of Plasmodium falciparum

Quintiles Transnational Corp. - John Ratliff appointed CFO of pharmaceutical services organization

Rinat Neuroscience - Clinical testing begins on RI 624 for acute and chronic pain

Rockefeller University - Proopiomelanocortin neuron inhibition is desensitization in ob/ob mice

Saitama Medical School - Sox-2 regulatory regions display activity in two types of multipotent stem cells

Saitama Prefectural University - Pomegranates shown to be effective for menopausal symptoms

Salk Institute for Biological Studies - Accelerated MDM2 auto-degradation is required for p53 activation

Sandoz Inc. - Pharmaceutical company begins shipping generic Levothyroxine sodium tablets

Sanquin Research CLB - IgG4-switched B cells may undergo secondary switch to IgE in allergen exposure

Schering-Plough Corporation - Millennium Pharmaceuticals reacquires European marketing rights for Integrilin

Scripps Research Institute - ARC protects against cell death through interaction with Bax

Scripps Research Institute - Ly6Chi helper T cells regulate plasma cell production

Scripps Research Institute - Method to assign chemical shifts of aromatic side chains developed

Secondhand Smoke - Reports highlights children's health consequences from secondhand smoke

Seoul National University - Therapeutic cloning no longer a dream, says scientist

Sexual & Reproductive Health - Test chemical increases sexual appetite in female rats

Shanghai Jiao Tong University - External heat treatment controls gene activation in muscle cells

Siemens Medical Solutions - 64-Slice CT scanner introduced for cardiac, thoracic, and vascular imaging

Sinisa Stankovic Inst. for Biological Research - Taxol induces nitric oxide production in astrocytes

Swiss Federal Inst. of Technology - Local neurotrophic factor expression rescues motoneurons in study animals

The Endocrine Society - Studies reveal high levels of anabolic steroid use by teenagers

The Medicines Company - European scientific panel recommends approval of Angiox

Thermogenesis Corp. - Fifth BioArchive order placed by cord blood bank company in Taiwan

Third Military Medical University - Epitope-specific cells don't lead hepatic injury in hepatitis B patients

Tianjin Zhongjin Biology Development Co. - KS E-Media Holdings acquires Chinese biomedical company

Tokyo Medical University - Novel human gene homologue found associated with cervical cancer

Tokyo Metropolitan University - Polyimide hollow-fiber oxygenator developed

Trudeau Institute - Regulatory CD38 activity clarified

U.S. Centers for Disease Control & Prevention - LC-MSMS multiresidue method to quantify pesticides in urine developed

U.S. National Cancer Institute - Mechanism for T cell association with tumor regression elucidated

U.S. National Institutes of Health - CD4+ regulatory T cells contribute to viral persistence

U.S. National Institutes of Health - Probabilistic regulation of IL-4 production in Th2 cells characterized

U.S. Smithsonian Environmental Research Center - West Nile virus control dependent on animal monitoring and disease research

Univ. Piemonte Orientale Amedeo Avogadro - Leptin is an important marker in gynecologic and breast cancers

Univ. of California, Los Angeles - Role of the calcium-sensing receptor in parathyroid gland physiology

Univ. of California, San Francisco - Mutation delineates role of melanocortin-4 receptor in humans

Univ. of California, Santa Cruz - Ultraconserved elements in the human genome reviewed

Univ. of Texas SW Medical Center - Cellular small ubiquitin-related modifier substrate proteins identified

University Clinic, Hamburg - SIOP trials and studies evaluate the prognosis of Wilms tumor patients

University College, London - The role of diet on the endothelium and atherosclerosis is not understood

University Hospital Aintree - Hyperglycemic crises and lactic acidosis in diabetes reviewed

University Hospital Basel - Infusion of two peptides acts to accelerate appetite satisfaction

University Hospital Eppendorf - Malignant peripheral nerve sheath tumor cells will advance drug research

University Joseph Fourier - Single cells keep good time

University at Buffalo - "Packaging" proteins makes them more stable for shipping as drug products

University at Buffalo - Study to consider college sports, gender and substance use

University of Bari - RNA extraction via oligo cellulose simplifies hepatitis A virus detection

University of Buenos Aires - Hormones, age, and fat distribution independently impair lipoprotein

University of California Irvine - Inflammatory and reactive arthropathies more prevalent in HIV infection

University of Cambridge - Herpesvirus protein degrades MHC-I peptide loading complex

University of Colorado - Telomerase limited as diagnostic adjunct in cervical cytopathology

University of Florida - Branched polymer guides plasmids into brain-derived cells

University of Florida - Doctors find clue to a mysterious kidney disease

University of Freiburg - Soluble EphB4 staunches tumor growth and angiogenesis in murine models

University of Georgia - Physical activity cuts risk of depression in children

University of Helsinki - Metalloproteinases exert differential expression in colon cancer tissue

University of Illinois - Angiotensin receptor inhibits ERK-2 activity via signaling pathway

University of Indonesia, Jarkarta - Brugia Rapid test detects filaria-specific IgG4 antibodies in endemic areas

University of Marburg - Olfactory neuroblastomas are genetically distinct entities

University of Miami - Depression in pregnancy impacts newborn, assessment scores indicate

University of Michigan - Wnt protein prevents obesity by inhibiting fat cell development

University of Missouri - IL-4 uses IL-13Ralpha1 to induce Th1 cell apoptosis in neonates

University of Navarra - Candidate genes for obesity reviewed

University of Navarra - Gene expression in adipose tissue determined by differential display

University of North Carolina - Scientists discover molecular pathway leading to nerve growth and regeneration

University of Paris - Organosulfur compounds from alliaceae may protect against cardiovascular disease

University of Pennsylvania - Dysbindin-1 reduced in hippocampus of schizophrenia patients

University of Pittsburgh - DC maturation by AdV transduction enhances tumor Ag-specific T cell response

University of Pittsburgh - Self-renewing divisions of hematopoietic SC increased in absence of P18(INK4C)

University of Pittsburgh - Sulfonylurea treatment of type 2 diabetes reviewed

University of Qingdao - Multiple vitamin deficiencies associated with anemia in last trimester

University of Sao Paulo - Novel mutation in PMP22 gene associated with variable phenotype

University of South Florida - Real-time PCR detection of Vibrio from mussels developed

University of Tokyo - Endostatin inhibition would aid collateral vessel growth after heart attacks

University of Toronto - p38 MAPK pathway critical for CD40L-mediated up-regulation of CD83

University of Tubingen - Utility of radiofrequency ablation of liver metastases reviewed

University of Verona - RhoA and zeta PKC control different modes of chemokine-induced LFA-1 activation

University of Virginia - Preventing HLA-A2-restricted peptide modification enhances antigenicity

University of Washington - Postoperative urinary and sexual function are concerns after prostatectomy

University of Wurzburg - Dendritic cell vaccine needs IL-2 for melanoma metastasis efficacy

Varian, Inc. - Narrow Bore Triple Resonance MAS probes introduced

Vasogen Inc. - VP015 reduces markers of inflammation in the brain, published data shows

Veridien Corporation - Healthcare company announces new board member

Veterans Administration - Yale researchers receive $4.5 million grant to study spinal cord repair

Viral Genetics, Inc. - Drug discovery company names new member to scientific and medical advisory board

Virginia Polytechnic Institute -  Mycobacterium avium cell fractions used for vaccine development

ViroLogic, Inc. - Biotechnology company names vice president of clinical research

ViroLogic, Inc. - Grant to fund assessment of HIV replication capacity

Vital Images, Inc. - Vitrea 2, Version 3.5 advanced visualization software announced

Washington University - CpG DNA redirects class-switching towards Th1-like Ig isotype production

Wright Medical Group, Inc. - Medical device manufacturer names new chief executive officer

Yale University - Patients may be willing to exchange less effective drugs for fewer side effects

Yong Dong Severance Hospital, Seoul - B-type natriuretic peptide level can assess extent of myocardial ischemia

Yonsei University - JNK activation may play role in pathogenesis

aaiPharma Inc. - Pharmaceutical company reports net revenue increase in first quarter 2004

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