Susan Hasty, Publisher
Table of Contents . . . July 23rd, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Biotech Law Weekly | Other Publications
Alaris Medical Systems - ICU Medical announces court order in patent infringement lawsuit
Biosystemix - Data mining, predictive modeling provided for personalized medicine models
CDEX - Alpha test of ValiMed impaired clinician solution initiated
CyDex, Inc. - Hovione enters drug-development alliance for potential new products
Ethicon Endo-Surgery, Inc. - Inamed Corp. reaches settlement of patent litigation over gastric banding
Genetronics Biomedical Corp. - Two patents awarded for applications of electroporation therapy
Georgia Reproductive Specialists - Human oocyte cryopreservation is an alternative to embryo cryopreservation
Healthcare Coverage - Plenaxis assigned Medicare permanent billing code for hospital use
Legal Issues - Three in Rite Aid scandal begin prison terms
Medicare/Medicaid - Mississippi governor extends Medicaid/Medicare switch deadline
National Geriatric Psychiatry Association - Group lauds law that would address geriatric mental health
Pain Medicine - Hospitals seek to spare children's pain
Prescription Fraud - Nebraska state senator arrested, accused of prescription fraud
Shandong University - Vein grafts remain patent following adenovirus-mediated gene delivery
U.S. Centers for Medicare & Medicaid Svcs. - Medicare boosts payments for ambulance transportation
Ludwig-Maximilians University, Munich - Trastuzumab combined with epirubicin and cyclophosphamide is safe for the heart
Aarhus University - TARTAR dimer therapeutic target for treatment of HIV-1 infection
Academia Sinica - Activity of analogs of influenza hemagglutinin fusion peptide described
Accumetrics, Inc. - Diagnostics company announces $13.5M financing
Affymetrix, Inc. - Immusol initiates collaboration to advance oncology drug-discovery efforts
Ajou University - Genistein may be an alternative to estrogen for treatment of AD
Alzheimer Disease - Alzheimer Association seeks annual $1B federal investment for research
American Health Care Association - Group claims billions in Medicaid funding lost from phase-out of fiscal relief
American Pharmaceutical Partners, Inc. - FDA grants approval for dimenhydrinate injection
Amgen Inc. - Neulasta lowers infection rate in myelosuppresive chemotherapy study patients
Amgen, Inc. - Biologics License Application submitted for FDA approval of Palifermin
Amrad - Australian anti-infectives business to be demerged
Analogic Corp. - Halifax Medical Center selects VERICIS from Camtronics
Arthritis - PA Health Department presents "State of Arthritis in Pennsylvania" report
ArthroCare Corp. - Coblation tonsillectomy offers more benefits than electrocautery, study shows
Association of the British Pharmaceutical Industry - New body will boost clinical trials in U.K., says industry group
Auxeris Therapeutics Inc. - Biopharmaceutical company names new chief scientific officer
Awards - PacifiCare receives National Exemplary Practice Award for diabetes program
Baystate Medical Center - Benefits of oral contraceptives far outweigh potential risks
Bentley Pharmaceuticals, Inc. - Approval granted to market generic versions of lansoprazole in Spain
BioSante Pharmaceuticals, Inc. - Phase II trial for LibiGel completed
Bridge Fertility Center, London - Chromosomal chaos in early development linked to abnormalities in cytokinesis
Cancer - Former cancer patient debuts cancer-fighting video game
Cancer Mortality - CDC: More people with cancer surviving
Cancer Therapy - NCI selects SRI to qualify cancer drug candidates for clinical studies
Cancer Treatment - Ocala Oncology inks agreement with Shands HealthCare, UF Health Science Center
Case Western Reserve University - Insulin under amyloidogenic conditions indicates protein-folding
Cedars Sinai Medical Center - Glioma tropic neural stem cells consist of astrocytic precursors
CellExSys, Inc. - Merger agreement with Chromos announced
Children's Hospital, Boston - Cutaneous immune sensitization is enhanced by antigen-independent IgE effects
Chiron Corporation - Nonexclusive HCV license granted to Prosetta
City Hospital Triemli, Zurich - Proton radiography can monitor patients who undergo proton radiotherapy
Cold Spring Harbor Laboratory - Microarray detection of transcription factor-binding motifs enhanced
College of New Jersey - Women with family history of breast/ovarian cancer find support in friends
Colorado Center for Reproductive Medicine - High protein diet may be bad for women trying to conceive
Corixa Corporation - Bacterial flagellin is dominant antigen in Crohn disease
CuraGen Corporation - Preclinical data presented on CG53135
CytRx Corporation - Alexander Cappello retires from board of directors at biotech company
DOBI Medical International, Inc. - Sales distribution agreement signed for the ComfortScan in India
DayMoon Scitech, Inc. - HemoGenix launches HALO hemotoxicity test platform in Korea
DePuy Mitek, Inc. - Bio-Intrafix launched for ACL repair
Durect Corporation - Agreement signed to develop treatments for inner ear disorders
EORTC Data Center - Quality-of-life data predict the survival of metastatic breast cancer patients
Emphasys Medical, Inc. - Device firm closes oversubscribed $27.5M round of private financing
Eyetech Pharmaceuticals, Inc. - Ophthalmology company names Michael J. Regan to the board of directors
Finance - Vantage Oncology, Inc., raises $15 million in Series B financing
Fundacion Valenciana de Investigaciones Biomedicas - Transcription factor essential in promoting Tomm70 gene expression
GPC Biotech, AG - New patent issued for cell-cycle inhibitor "composition of matter"
Gentiae Clinical Research, Inc. - LifeSignals platform to include Enterprise ECG data warehousing solution
Health Canada - Researchers identify occupational exposures that increase NHL risk
Healthnostics, Inc. - H-Quotient announces major software sale and listing change
Heart Research Institute, Sydney - Raising HDL levels may increase longevity
INRA - Phage protein confers resistance to lactococcal abortive mechanism
Icagen, Inc. - Ion-channel-target focused company taps Mark J. Suto, PhD
Iconix Pharmaceuticals, Inc. - ICOS enters chemogenomics collaboration
Imperial College, London - HIV-1 immune response differs in exposed seronegative and seropositive partners
Influenza - 100 million doses of flu shots to be available
Information Technology - Thomson PDR and ZixCorp to enhance ePrescribing solution
InnaPhase Corporation - Newton LIMS selected for quality control manufacturing facility in Spain
Innsbruck University - Interleukin-6 stimulates VEGF autocrine loops in prostate cancer cells
Institute Butantan - Kininogen inhibits metalloproteinases of Bothrops jararaca venom
Institute Jean Godinoi, Reims - Chlamydia pneumoniae infection is unrelated to squamous cell carcinoma
International Agency for Research on Cancer - Plasma tests for Ser-249 TP53 mutations disclose liver cancer status
International Diabetes Federation - Diabetes and obesity epidemic in children spurs international call to action
Intradigm Corp. - SARS Coronavirus siRNA inhibitors achieve prophylactic and therapeutic effects
Johns Hopkins University - The HMG-I oncogene is overexpressed in human leukemia
Karolinska Hospital - MMP-13 is androgen-regulated in prostate cancer
King Faisal Specialist Hospital & Research Centre - Mixture modeling can improve quality of DNA microarray data
Kitasato University - Novel allogeneic cultured dermal substitute system shows promise
Kongsvinger Hospital - Floride and bisphosphonates make a nice cocktail for the bones
Kyoto University - Differentially expressed molecules in adult T-cell leukemia cells identified
Kyung Hee University - Exercise suppresses NPY in hypothalamus of food-deprived rats
Life Force International - Survey: Consumers confused about the right combination of supplements
Liquent, Inc. - Company unveils product registration, submission lifecycle-management solutions
Mayo Clinic - Cardiac xenotransplantation may be feasible in the future
Medical College of Wisconsin - EBMT Risk Score for CML patients receiving stem cell transplants is validated
Medidata Solutions - Company launches unified platform for eCDM: RAVE 5.0
Merix Bioscience, Inc. - Companies to develop personalized dendritic-cell vaccines
MicroIslet, Inc. - Islet-cell transplantation studies in primates to be conducted at UC Davis
Misys Healthcare Systems - Laboratory-Collection Manager launched to enhance specimen-collection accuracy
National Cancer Center, Japan - Eating patterns in Japan predict risks for women, men
National Inst. for Medical Research, London - Role of ICOS signaling elucidated
Natl. Defense Medical College, Tokorozawa - FISH analysis of p53 and chromosome 17 has limited prognostic value
Nerima Hikarigaoka Nihon Univ. Hospital - GRAP gene may be involved in Sjogren syndrome pathogenesis
New York University - Controversies in laparoscopic adjustable gastric banding outlined
Nippon Medical College, Tokyo - Severe head injury can cause cardiopulmonary disturbance
North Shore Univ.-Long Island Jewish Hlth. System - Improved pediatric cranioplasty technique developed
NuVasive, Inc. - Spine-focused company underwriters exercise over-allotment option
Nutrition - Some healthy eaters say they are hefty
Ohio State University - Tyrosine phosphorylated disabled 1 recruits Crk family adapter proteins
Okayama University - Stimulated CD40 ligand stops mantle cell lymphoma proliferation
Oregon Health & Science University - Tuberculosis immunology in children reviewed
Osaka University - ABCG2 positive limbal epithelial cells putative corneal epithelial stem cells
Osaka University - Electrogastrography helps determine pathophysiology of eating disorders
Oxford University - Genetic basis for metabolic diseases detected
Partners AIDS Research Center, Cambridge - Antigen-specific T cells migrate away from CXCR4-binding HIV-1 gp120
Paterson Institute of Cancer Research - Adoptive transfer of anti-idiotypic T cells cure B cell lymphoma
Pennsylvania State University - Childhood sports involvement predicts participation in sports as adult
Personnel - Martha Schram named president of Aegis Therapies, SVP of Beverly Enterprises
Planar Systems, Inc. - FDA approves marketing of flat-panel DomeC5i system for mammograms
Pontificia University of Catolica Chile - Large pathogenicity island in Salmonella enterica excised
Pro-Pharmaceuticals, Inc. - Davanat with 5-FU well tolerated in study patients with advanced solid tumors
Purdue University - Artificial sweetener may disrupt body's ability to count calories
Queensland Institute of Medical Research - CLAG 9 is located in rhoptries of Plasmodium falciparum
Quintiles Transnational Corp. - John Ratliff appointed CFO of pharmaceutical services organization
Rinat Neuroscience - Clinical testing begins on RI 624 for acute and chronic pain
Rockefeller University - Proopiomelanocortin neuron inhibition is desensitization in ob/ob mice
Saitama Medical School - Sox-2 regulatory regions display activity in two types of multipotent stem cells
Saitama Prefectural University - Pomegranates shown to be effective for menopausal symptoms
Salk Institute for Biological Studies - Accelerated MDM2 auto-degradation is required for p53 activation
Sandoz Inc. - Pharmaceutical company begins shipping generic Levothyroxine sodium tablets
Sanquin Research CLB - IgG4-switched B cells may undergo secondary switch to IgE in allergen exposure
Schering-Plough Corporation - Millennium Pharmaceuticals reacquires European marketing rights for Integrilin
Scripps Research Institute - ARC protects against cell death through interaction with Bax
Scripps Research Institute - Ly6Chi helper T cells regulate plasma cell production
Scripps Research Institute - Method to assign chemical shifts of aromatic side chains developed
Secondhand Smoke - Reports highlights children's health consequences from secondhand smoke
Seoul National University - Therapeutic cloning no longer a dream, says scientist
Sexual & Reproductive Health - Test chemical increases sexual appetite in female rats
Shanghai Jiao Tong University - External heat treatment controls gene activation in muscle cells
Siemens Medical Solutions - 64-Slice CT scanner introduced for cardiac, thoracic, and vascular imaging
Sinisa Stankovic Inst. for Biological Research - Taxol induces nitric oxide production in astrocytes
Swiss Federal Inst. of Technology - Local neurotrophic factor expression rescues motoneurons in study animals
The Endocrine Society - Studies reveal high levels of anabolic steroid use by teenagers
The Medicines Company - European scientific panel recommends approval of Angiox
Thermogenesis Corp. - Fifth BioArchive order placed by cord blood bank company in Taiwan
Third Military Medical University - Epitope-specific cells don't lead hepatic injury in hepatitis B patients
Tianjin Zhongjin Biology Development Co. - KS E-Media Holdings acquires Chinese biomedical company
Tokyo Medical University - Novel human gene homologue found associated with cervical cancer
Tokyo Metropolitan University - Polyimide hollow-fiber oxygenator developed
Trudeau Institute - Regulatory CD38 activity clarified
U.S. Centers for Disease Control & Prevention - LC-MSMS multiresidue method to quantify pesticides in urine developed
U.S. National Cancer Institute - Mechanism for T cell association with tumor regression elucidated
U.S. National Institutes of Health - CD4+ regulatory T cells contribute to viral persistence
U.S. National Institutes of Health - Probabilistic regulation of IL-4 production in Th2 cells characterized
U.S. Smithsonian Environmental Research Center - West Nile virus control dependent on animal monitoring and disease research
Univ. Piemonte Orientale Amedeo Avogadro - Leptin is an important marker in gynecologic and breast cancers
Univ. of California, Los Angeles - Role of the calcium-sensing receptor in parathyroid gland physiology
Univ. of California, San Francisco - Mutation delineates role of melanocortin-4 receptor in humans
Univ. of California, Santa Cruz - Ultraconserved elements in the human genome reviewed
Univ. of Texas SW Medical Center - Cellular small ubiquitin-related modifier substrate proteins identified
University Clinic, Hamburg - SIOP trials and studies evaluate the prognosis of Wilms tumor patients
University College, London - The role of diet on the endothelium and atherosclerosis is not understood
University Hospital Aintree - Hyperglycemic crises and lactic acidosis in diabetes reviewed
University Hospital Basel - Infusion of two peptides acts to accelerate appetite satisfaction
University Hospital Eppendorf - Malignant peripheral nerve sheath tumor cells will advance drug research
University Joseph Fourier - Single cells keep good time
University at Buffalo - "Packaging" proteins makes them more stable for shipping as drug products
University at Buffalo - Study to consider college sports, gender and substance use
University of Bari - RNA extraction via oligo cellulose simplifies hepatitis A virus detection
University of Buenos Aires - Hormones, age, and fat distribution independently impair lipoprotein
University of California Irvine - Inflammatory and reactive arthropathies more prevalent in HIV infection
University of Cambridge - Herpesvirus protein degrades MHC-I peptide loading complex
University of Colorado - Telomerase limited as diagnostic adjunct in cervical cytopathology
University of Florida - Branched polymer guides plasmids into brain-derived cells
University of Florida - Doctors find clue to a mysterious kidney disease
University of Freiburg - Soluble EphB4 staunches tumor growth and angiogenesis in murine models
University of Georgia - Physical activity cuts risk of depression in children
University of Helsinki - Metalloproteinases exert differential expression in colon cancer tissue
University of Illinois - Angiotensin receptor inhibits ERK-2 activity via signaling pathway
University of Indonesia, Jarkarta - Brugia Rapid test detects filaria-specific IgG4 antibodies in endemic areas
University of Marburg - Olfactory neuroblastomas are genetically distinct entities
University of Miami - Depression in pregnancy impacts newborn, assessment scores indicate
University of Michigan - Wnt protein prevents obesity by inhibiting fat cell development
University of Missouri - IL-4 uses IL-13Ralpha1 to induce Th1 cell apoptosis in neonates
University of Navarra - Candidate genes for obesity reviewed
University of Navarra - Gene expression in adipose tissue determined by differential display
University of North Carolina - Scientists discover molecular pathway leading to nerve growth and regeneration
University of Paris - Organosulfur compounds from alliaceae may protect against cardiovascular disease
University of Pennsylvania - Dysbindin-1 reduced in hippocampus of schizophrenia patients
University of Pittsburgh - DC maturation by AdV transduction enhances tumor Ag-specific T cell response
University of Pittsburgh - Self-renewing divisions of hematopoietic SC increased in absence of P18(INK4C)
University of Pittsburgh - Sulfonylurea treatment of type 2 diabetes reviewed
University of Qingdao - Multiple vitamin deficiencies associated with anemia in last trimester
University of Sao Paulo - Novel mutation in PMP22 gene associated with variable phenotype
University of South Florida - Real-time PCR detection of Vibrio from mussels developed
University of Tokyo - Endostatin inhibition would aid collateral vessel growth after heart attacks
University of Toronto - p38 MAPK pathway critical for CD40L-mediated up-regulation of CD83
University of Tubingen - Utility of radiofrequency ablation of liver metastases reviewed
University of Verona - RhoA and zeta PKC control different modes of chemokine-induced LFA-1 activation
University of Virginia - Preventing HLA-A2-restricted peptide modification enhances antigenicity
University of Washington - Postoperative urinary and sexual function are concerns after prostatectomy
University of Wurzburg - Dendritic cell vaccine needs IL-2 for melanoma metastasis efficacy
Varian, Inc. - Narrow Bore Triple Resonance MAS probes introduced
Vasogen Inc. - VP015 reduces markers of inflammation in the brain, published data shows
Veridien Corporation - Healthcare company announces new board member
Veterans Administration - Yale researchers receive $4.5 million grant to study spinal cord repair
Viral Genetics, Inc. - Drug discovery company names new member to scientific and medical advisory board
Virginia Polytechnic Institute - Mycobacterium avium cell fractions used for vaccine development
ViroLogic, Inc. - Biotechnology company names vice president of clinical research
ViroLogic, Inc. - Grant to fund assessment of HIV replication capacity
Vital Images, Inc. - Vitrea 2, Version 3.5 advanced visualization software announced
Washington University - CpG DNA redirects class-switching towards Th1-like Ig isotype production
Wright Medical Group, Inc. - Medical device manufacturer names new chief executive officer
Yale University - Patients may be willing to exchange less effective drugs for fewer side effects
Yong Dong Severance Hospital, Seoul - B-type natriuretic peptide level can assess extent of myocardial ischemia
Yonsei University - JNK activation may play role in pathogenesis
aaiPharma Inc. - Pharmaceutical company reports net revenue increase in first quarter 2004
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