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Biotech Law Weekly

Susan Hasty, Publisher

Table of Contents . . . August 20th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Law Weekly | Other Publications

Ablynx - Nanobody drug discovery and development partnership signed

CardioGenesis Corp. - Medicare panel's review of myocardial revascularization complete

Collaborations - Gold Standard, ACP to integrate and market Clinical Pharmacology, PIER Products

Cutting Edge Information - Generic drug sales to exceed $60 billion by 2007

Exeter Life Sciences - ViaGen parent establishes biotech IP, licensing, and investment division

Genetronics Biomedical Corp. - Tumor-focused biomedical company wins another electroporation patent

Kaiser Family Foundation - Study examines Medicare drug cards

Legal Issues - "Cancerphobia" lawsuits out of proportion to actual breast cancer risk

Legal Issues - Invacare Corporation files patent infringement lawsuit for SureStep technology

Legal Issues - Wyeth wins one diet drug lawsuit, settles another

Mental Health - New Hampshire state prisoners sue for better mental health care

Pennsylvania Attorney General - State attorney general says consumers will receive $1.6 million drug settlement

Phoenix Biosciences, Inc. - Patent issued for immunological method to reduce HIV activity

Prescription Drugs - GlaxoSmithKline criticizes decision to hear pricing complaint on AIDS drug

Prescription Drugs - Louisiana state organizations working to publicize Medicare drug cards

AGY Therapeutics, Inc. - Stroke recovery product candidate licensed for phase II development

ATS Medical, Inc. - Heart valve maker reports 78% second quarter revenue growth

AVVAA World Health Care Products - Product distribution agreement signed by biotech firm for the Philippines

Abbott Laboratories - Feeling full not the only key to obesity

Accuray Incorporated - New respiratory tracking system launched

Acurian, Inc. - Pharmaceutical companies use Recruitment Manager software

Advanced Magnetics, Inc. - Pharmaceutical company reports quarterly loss of $0.10 per share

Adventrx Pharmaceuticals, Inc. - Biopharmaceutical company completes move to new facility

Affymetrix, Inc. - GeneChip maker reports income of $0.12 per share

Agensys, Inc. - Cancer biotech firm signs deal with Genentech

Alamo Pharmaceuticals - New FazaClo orally disintegrating tablets launched for schizophrenia patients

Alcohol Abuse - Study looks at alcohol-related victimization of women in college

Allergy Medicine - FALCPA awaits Bush's signature; advocacy group praises legislation

American Heart Association - Experts make recommendations about air pollution and cardiovascular disease

American Pharmaceutical Partners, Inc. - Tentative approval granted for Esmolol Hydrochloride injection

Ascend Therapeutics - Andrin trial launched in Australia

Assn. Advancement of Medical Instrumentation - Should medical equipment management take place inside or outside the hospital?

AstraZeneca - Data supports SEROQUEL use to reduce agitation associated with Alzheimer disease

AstraZeneca - Medication helps quell the agitation of dementia

Baylor College of Medicine - Protein key to trafficking in nerve terminals

Baylor Institute Immunology Research - Dendritic cell vaccine causes expansion of melanoma-specific T cells

Bichat-Claude Bernard University Hospital - Infective endocarditis characterized in pacemaker recipients

Bio-One Corporation - Supplement maker to acquire majority interest in $17M Chinese firm

Biolase Technology, Inc. - Device firm anticipates 48-50% increase in revenue

Biomira, Inc. - Phase II ovarian cancer trial commences

Biosite Incorporated - Diagnostics firm reports earnings grew in excess of 30%

Boston Scientific Corporation - Device firm reports 71% increase in net sales

Brain Tumor - Nutritional rehabilitation may help growth in pediatric brain cancer patients

Breast Cancer - Poorer Scottish women in dark over breast cancer

Bristol Myers Squibb Co. - Atazanavir suppresses HIV with extended use and in nelfinavir-switched patients

Bristol-Myers Squibb Company - Pharmaceutical firm reports earnings of $0.27 per share

Business Update - Mylan to buy King Pharmaceuticals for about $4 billion in stock

CHU Laval, Quebec City - Insertion of CD80 (B7.1) and CD86 (B7.2) into HIV-1 affects virus life cycle

CHU Treichville 18, Abidjan - Acceptance of HAART intervention independent of maternal immune status

CSIC - First neurodegenerative event in Alzheimer disease evaluated

Cambrex Corporation - Biotech company reports income of $0.23 per share

Cancer Genetics - Alcohol, but not dietary antioxidants, linked to increased p53 mutation risk

Canisius Wilhelmina Hospital, Nijmegen - Response surface approach able to interpret antifungal interactions

Carnegie Mellon University - Researchers discover biological basis for autism

Cedars-Sinai Medical Center - New minimally invasive approach to upper lumbar fusion reduces complication risk

Cell Genesys, Inc. - Company demands delisting of its common stock from Berlin-Bremen Stock Exchange

Chembio Diagnostics, Inc. - Clinical trial commences for HIV rapid test

ChromaVision Medical Systems, Inc. - Diagnostics company names Ronald A. Andrews, Jr. CEO

Cleveland Clinic - Intracerebral hemorrhage leads to systemic upregulation of angiotensin II type 1

Clinical Data Interchange Standards Consortium - Agency announces standard format to submit human drug clinical trial data

Clinique Font Redonde, Figeac - Great saphenous vein leiomyosarcoma characterized

Curis, Inc. - Childhood brain cancer linked to deletion of a Hedgehog pathway suppressor

CytRx Corp. - RNAi company names Jack R. Barber, PhD, senior VP, drug development

DENTSPLY International, Inc. - Dental-prosthetics company declares quarterly cash dividend

Dartmouth College - Real-time RT-PCR measures spinal glial response marker following nerve injury

Dartmouth Medical School - MRI shows ability to distinguish possible early AD and effects of treatment

Depomed, Inc. - NDA submitted for Proquin XR - Ciprofloxacin GR

Disease Management - Oregon's largest insurers see benefits of programs that focus on preventive care

EiRx Therapeutic Ltd. - Mithramycin A sensitizes tumor cells to apoptosis induced by TNF

Emory University - Nanoparticle quantum dots simultaneously target and image tumors in mice

Endocrinology - hCG molecule has high thyrotropic activity in women with trophoblastic disease

Eppendorf Array Technologies - DNA microarrays used as a tool in toxicogenomics

Evotec OAI AG - Morphochem selects partner for chemical, pharmaceutical development of Oxaquin

Food Allergy Initiative - Food allergen labeling act approved by Congress applauded

Free University of Brussels - Bone marrow endothelial cells studied in ongoing angiogenesis

Fudan University, Shanghai - Novel S-DABO derivatives inhibit HIV-1 and HIV-2

Garvan Institute of Medical Research - Transcriptional profile of T follicular helper cells determined

Guidant Corporation - Voyager rapid-exchange Coronary Dilatation Catheter launches

Hannover Medical School - Monoclonal antibodies as markers of lymphatic vessels studied in horse model

Health Canada - Potential mutational hot spot found in meningococci serotype antigens

Health Protection Agency, London - Horse erythrocytes aid detection of anti-influenza responses in sera

Healthcare Focus - American Indian physicians focus on adolescents, students

Hormone Replacement Therapy - Vaginal progesterone gel has high local endometrial effect, no systemic effects

Hospital de Weezenlanden - Ticlopidine, clopidogrel comparably effective during coronary stenting

Hungarian Academy of Science - Gamma-aminobutyric acid has role in early neuronal development

IMPAC Medical Systems, Inc. - DTMI under development for radiation oncology at M. D. Anderson Cancer Center

IRIDEX Corporation - Laser systems provider reports improved second quarter operating performance

Inflazyme Pharmaceuticals Ltd. - Pharmaceutical company to refocus research and development efforts

Inspire Pharmaceuticals, Inc. - Biopharmaceutical company prices public offering of common stock

Institute of Health Carlos III - Antigenic variation of PorA protein in Neisseria investigated

Intuitive Surgical, Inc. - Operative surgical robotics manufacturer announces record second quarter sales

Inveresk Research Group, Inc. - Drug development services company reports second quarter financial results

Johns Hopkins Medical Institute - Culture matrix influences RPE cell gene expression

Johns Hopkins University - Scientists suggest framework for studying common diseases

Kantonsspital, Basel - HSCT toxic but effective in refractory autoimmune cytopenia patient subset

Kensey Nash Corporation - 510(k) application submitted to FDA for TriActiv System for stent procedures

Kyunghee University - Electro-acupuncture modulates Th1/Th2 cell response

Laserscope - Medical laser systems manufacturer reports record revenues in second quarter

Leiden University - Study finds liver is hyper-responsive to GH action in abdominally obese women

Lerner Research Institute - A role for Nogo in neurodegenerative disease?

Lipid Studies - Effects of HRT, tibolone, raloxifene on lipid levels compared in Greek women

Loma Linda University - Treatment decisions might not be consistent with advance directives

Lonza - Biopharmaceutical manufacturer to offer Niamax to U.S. nutrition industry

Lumenis Ltd. - IPL Quantum SR to be used in photorejuvenation clinical study

Lund University -  H. pylori vacA and cagA genotypes seen more in chronic active gastritis

Mario Negri Inst. for Pharmacological Research - C1-inhibitor has powerful C1q-independent effects after brain ischemia

Mary Ann Liebert Inc. - Stem cell journal papers available free online through November 2, 2004

Massachusetts General Hospital - SIV-induced metabolic brain abnormalities reversed with virus control

Max-Planck-Institute for Dyn. of Comp. Tech. Sys. - Metabolism of MDCK cells during influenza virus production described

Medical University of Gdansk - Dehydroepiandrosterone up-regulates resistin gene expression

Medical University of Silesia - H3 mRNA level new proliferative marker in astrocytomas

Merck Research Laboratories - Novel fungal polyketide inhibits HIV-1 integrase activity

Mount Sinai School of Medicine - Combining radiation modalities increases success

NIBSC, Potters Bar - In vitro test systems compared

NOVAVAX, INC. - ESTRASORB rights to be reacquired from King Pharmaceuticals

National Jewish Medical & Research Center, Denver - IL-1 receptor antagonist attenuates airway hyperresponsiveness to ozone

New York Medical College - Live flavivirus vaccines require caution

Northwestern Hospital, Chicago - Research shows progress toward early identification of anthrax inhalation

Nursefinders Inc. - VHA enters agreement for nurse staffing and vendor management services

OfficeWorksRx - Healthcare recruitment and staffing company boasts growth, opens new offices

Ondokuz Mayis University - Hepatitis B genotype D distinguished from non-D using polymerase chain reaction

Orphan Medical, Inc. - Pharma company announces second quarter results

Ospedale San Martino, Genoa -  B. clausii can lower cytokine output in children

Owens &, Minor, Inc. - Medical and surgical supply company releases second quarter results

Pan American Health Organization - AIDS in Latin America: A controllable epidemic?

PerkinElmer, Inc. - Assay kits now available in Europe detect down syndrome in first trimester

Pharmos Corporation - Pharmaceutical company appoints chief financial officer

Picis - Calgary Health Region adds operating room management to anesthesia software

Polytechnical University of Marche - Ultrasound reveals pregnancy-induced reduction in maternal bone mass

Prescription Drugs - Florida fails to renew drug programs sponsored by Pfizer, others

Private Healthcare Systems - Health care cost management company acquires two PPO networks

QualityMetric Incorporated - Royalty-free access to health assessment software for research announced

Quick-Med Technologies, Inc. - Life sciences company signs agreement with Morgan Keegan & Company

Quigley Corporation - Health products developer dismisses accountants, enlists new independent firm

R.J. Reynolds Tobacco Company - Tobacco company says Senate tobacco bill would hurt growers, industry

Regeneration Technologies, Inc. - Orthopedic, cardiovascular and allograft processor announces financial results

Roche - Application filed with U.S. FDA to market hepatitis C medication for hepatitis B

Roche - Journal publishes results of PEGASYS trial in HIV-HCV co-infected patients

Royal Melbourne Hospital - Selective site pacing locations should defined

Royal Oak Medical Center - Urgent care center earns accreditation from trade association

Royal Philips Electronics - FDA panel considers over-the-counter home defibrillator

Ruhr University of Bochum - Pathology, classification, and staging of lung tumors studied

SEQUENOM,Inc. - U.S. National Institutes of Health expands relationship with genetics company

Santo Holding, GmbH - Eon Labs announces filing of secondary shelf registration statement

Schering AG - Pharma company releases financial results, names vice president

Schering-Plough Corporation - Drug company reports lower sales and earnings for 2004 second quarter

Slovak Cardiovascular Institute - Further study needed to determine efficacy of right ventricular pacing

SomaLogic, Inc. - Proteomics company acquires rights to DNA modification chemistry patents

Spectranetics Corporation - New vascular catheter sales fuel record 32% quarterly revenue jump

Swiss Institute Allergy & Asthma Research - Immune responses characterized by allergen-specific T cells

Sysmex America, Inc. - Clinical lab developer installs multi-lab software for Esoterix

Tapestry Pharmaceuticals, Inc. - Pharmaceuticals companies collaborate on cancer therapeutics

Target Discovery, Inc. - Company launches pre-coat reagents to address biochemical separation issues

Terumo Cardiovascular Systems - Cardiovascular company expands distribution agreements with Spencer Technologies

Teva Neuroscience - On the horizon: Possible neuroprotective role for glatiramer acetate

The Center for Consumer Freedom - Consumer freedom group says obesity is not a disease

The Perrigo Company - Over-the-counter drug manufacturer acquire certain assets of APG, Inc.

ThermoGenesis Corp - Blood cell container patent for improved cryopreservation issued

Thomas Jefferson University - New generation of SNV-based vectors may be used to block HIV-1 replication

Tissera, Inc. - Biotech company comments on diabetes therapy patent application

Tokyo Women's Medical College - Integrated disease management program decreases mortality in type 1 diabetes

Tottori University - The protein p62 has a role in protecting cells from misfolded proteins

Translational Genomics Research Institute - Researchers identify gene for a primary form of SIDS

U.S. Centers for Disease Control & Prevention - Contributions made by social scientists to malaria control reviewed

U.S. Centers for Disease Control & Prevention - Issues of transnational research on intimate partner violence discussed

U.S. Centers for Disease Control & Prevention - Method for enhanced culture recovery of Francisella tularensis reported

U.S. Centers for Disease Control & Prevention - Performance of rapid HIV antibody detection assays evaluated

U.S. Centers for Disease Control & Prevention - Prevalence of the metabolic syndrome in U.S. populations reported

U.S. Centers for Disease Control & Prevention - Pulmonary delivery of RSV vaccines achieved via albumin particles

U.S. Centers for Disease Control and Prevention - Information-only prevention efforts not enough to encourage HIV testing

U.S. Centers for Disease Control and Prevention - Pediatricians embrace assisting parent-child communication about HIV

U.S. Centers for Disease Control and Prevention - Social anxiety linked to risky sex in HIV-positive men who have sex with men

U.S. Food & Drug Administration - Herpesvirus-specific glycoprotein captured by immunomagnetic method

U.S. Food and Drug Administration - FDA charges Metabolife and its founder with deceptions

U.S. National Institutes of Health - Negative relation exists between ghrelin level and food intake

U.S. Walter Reed Army Medical Center - HHV-6 reactivation caused TMA and stroke in SCT and high-dose melphalan patient

USANA Health Sciences Inc. - Personal care products maker reports record second quarter results

Univ. of California, San Diego - Gender does not affect human pulmonary gas exchange during exercise

Univ. of Illinois, Urbana-Champaign - Scientists build on case connecting inflammatory disease and depression

Universite de la Mediterranee - Risk factors for severe malaria in Bamako, Mali reported

University College London - Sex education taught by pupils a new approach to tackling STDs

University of Aberdeen - Allometric scaling using body mass power laws yields inaccurate results

University of Auckland - Physician perspectives on childhood immunization barriers outlined

University of Autonoma Madrid - Long-term suppression of HIV RNA with HAART occur despite virus evolution

University of Basel -  TRIO upregulated in urinary bladder tumors

University of Bonn - Uterine stimulation with E2 and OT modulates oxytocin receptor expression

University of British Columbia - GnRH-II stimulates p38 MAPK and apoptosis in ovarian cancer cells

University of Calgary - Technique developed for segmentation of the fibro-glandular disc

University of Cambridge - Genomic and metabolic effects of fatty liver disease clarified

University of Cincinnati - Sub-compartmentalization of GI immune system determined with microbeads

University of Connecticut - Zygomatic skeletal anchorage effective in open bite treatment

University of Edinburgh - Getting to the bottom of the burger bug

University of Frankfurt - Dystrophin disruption may contribute to enterovirus-induced myocarditis

University of Hawaii, Manoa - Progesterone and glucocorticoids can differentially regulate relaxin genes

University of Hong Kong - TGF-beta1 polymorphisms linked to bone loss risk in southern Chinese women

University of Iowa Hospitals & Clinics - Marijuana use can cause tolerance to heart rate changes

University of Kentucky - Ribinucleotide reductases attenuate efficacy of abacavir

University of Laval - Nocturnal hot flashes contribute to insomnia in survivors

University of Leicester - Lymphocyte telomere erosion not increased in patients

University of Leipzig - PPAR-gamma coactivator-1 variant not associated with diabetes-related traits

University of Massachusetts - Two models defining nutrition education presented

University of Michigan - Circadian differences in HPA axis hormones found in FMS and CFS patients

University of Milan - Sympathetic overactivity may persist after acute myocardial infarction

University of Minnesota - Capillary electrophoretic test detects alpha-tubulin in nuclear preparations

University of Minnesota - Parents are top influence on soft-drink consumption among kids

University of Munster - Single-nucleotide polymorphism may be associated with panic disorder in women

University of Oklahoma - Polymer encapsulation improves plasminogen activator efficacy

University of Oxford - Enrichment technique to detect hepatitis-specific T cells studied

University of Paris 07 - Disruption of MKK4 signaling reveals its tumor-suppressor role in ESC

University of Passo Fundo - Compared drug doses for hemorrhagic syndrome from venomous caterpillar effective

University of Pennsylvania - WXPN and Musicians on Call will take healing music to hospitalized children

University of Queensland - Estrogenic regulation of brain angiotensinogen studied

University of Regensburg - Steroid sulfatase inhibitors inhibit MCF-7 breast cancer cell gene activation

University of Sao Paulo - Hypercaloric diet-induced UCP3 expression impaired by hypothyroidism

University of Sheffield - Autonomic neuropathy influences QTc interval lengthening during hypoglycemia

University of Southern California - Study suggests antipsychotics do not raise risk of stroke

University of Tokyo - Viral components other than hemagglutinin protective in influenza model

University of Toronto - Microglia-expressed MRPs may restrict permeation of antiretroviral drugs

University of Wales - Reference values for Doppler indices of LV diastolic filling established

University of Washington - High-throughput MS system suitable for neuronal proteome analysis

University of Wisconsin - Novel statistical model devised for ultrasonography errors

University of York - Quality group unrealistic in some recommendations to British healthcare service

Upstate - Cell research company promotes Ian W. Ratcliffe to president and COO

Valence Technology, Inc. - Battery developer and Graham-Field Health Products enter 3-year agreement

Vascular, Solutions, Inc. - Medical device developer announces record second quarter 2004 results

Ventana Medical Systems Inc. - Lab equipment company reports second quarter 2004 revenue growth of 27%

Ventracor Limited - Australian device maker comments on progress

Victorian Infection Diseases Reference Laboratory - Number needed to vaccinate developed for vaccine programs

Washington State Medical, Association - Report on patient safety in Washington state released

Weill Cornell Medical College - "Designer mice" yielding up secrets of deadly brain disease

West Nile Virus - Firms race for dominance of West Nile virus blood testing market

Whatman, Inc. - Agreement reached in patent infringement suit for DNA technology

Wilhelminen Hospital, Vienna - Anticardiolipin antibodies may predict restenosis after coronary angioplasty

Wilson Health Information - Adults, seniors report differences in pharmacy, drug cost satisfaction

ZymoGenetics - Phase 1b clinical trial underway to study potential immunotherapy

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