U.S. National Institutes of Health

Researchers uncover how HIV causes abnormalities in antibody-producing cells

Published in Biotech Law Weekly, October 1st, 2004

HIV wreaks much of its damage by targeting the "orchestra conductor" of the immune system, a key class of T cells - CD4+ T cells - whose destructive relationship with HIV has been well-studied by AIDS researchers. More poorly understood has been the effect of HIV on another key class of immune cells, antibody-producing B cells.

The malfunction of B cells in HIV-infected patients was first described more than 20 years ago by H. Clifford Lane, MD, Anthony S. Fauci, MD, and colleagues at the National Institute of Allergy and Infectious Diseases (NIAID) of the U.S. National Institutes of Health (NIH).

Now, writing in the September 7, 2004, online edition...

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Source: Biotech Law Weekly (2004-10-01)

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