Susan Hasty, Publisher
Table of Contents . . . October 29th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Biotech Law Weekly | Other Publications
Hollis-Eden Pharmaceuticals, Inc. - Neumune improves survival in non-human primates after radiation exposure
BTG - Agreement signed with the University of Illinois to develop sleep therapy
BioElectronics Corporation - Medicare to reimburse electromagnetic therapy for chronic wounds
BioInvent International AB - Alliance to develop antibody-based therapeutics for vascular indications
Carrington Laboratories, Inc. - Patent issued for drug delivery system
GenoMed, Inc. - Translational medical genomics company creates ethics committee
HEALTHPOINT, Ltd. - Company launches ACCUZYME spray, a new pump method of delivery
HIV/AIDS Treatment - Man claims doctor refused to perform surgery because of HIV
Legal Issues - Doctor pleads guilty to healthcare fraud
Legal Issues - Drug firms, doctors sued over suicide
Legal Issues - Watchdog report suggests background checks for Mississippi pharmacists
Medtronic, Inc. - Proposed ruling will broaden access to defibrillators for Medicare patients
Nastech Pharmaceutical Company Inc. - Pharmaceutical company acquires rights in intranasal delivery of PYY
Novartis AG - Zelnorm effective, well tolerated in irritable bowel syndrome with constipation
Provectus Pharmaceuticals - Pharma company announces new patent for therapeutic medical device
HemoSense, Inc. - Cardinal Health to market, sell, and distribute INRatio product line in U.S.
Human Genome Sciences, Inc. - Trial results demonstrate safety, tolerability of HGS-ETR1 in advanced cancers
A.C. Camargo Cancer Hospital, Buenos Aires - Totally implantable femoral vein catheters safe and effective
Accenture - Industry group announces results of pharma supply chain technology tests
Access Pharmaceuticals, Inc. - FDA approves OraDisc A delivery system NDA for canker sores
Aclara BioSciences - ETAG potential reported in cancer drug development prognosis
Adherex Technologies, Inc. - Oncology company reports yearly loss of $0.10 per share
Alaris Medical Systems, Inc. - Three-year dual source agreement signed for IV Smart Pump, Smart Systems
Albert-Ludwigs-Universitat Freiburg - Isotype-specific degradation of Rac investigated
Alexion Pharmaceuticals, Inc. - Pharmaceuticals firm reports fourth quarter results, $4M milestone payment
Alliance Pharmaceutical Corp. - Pharmaceutical company restructures recently completed financing
American Esoteric Laboratories, Inc. - American Esoteric Laboratories acquires Memphis Pathology Laboratory
Animas Corporation - Insulin pump users notified of software bug
Antigen Express - Generex Biotechnology establishes CRADA
Antisense Therapeutics - Company seeks to begin proof of concept study for ATL1101 in psoriasis
Applied Medical - Universal seal selected as innovations of the year by society
ArQule, Inc. - Preliminary interim phase I data presented for ARQ 501
Arius Research, Inc. - Biotech company completes private placement with Value Fund L.P.
Arkansas Children's Nutrition Center - Increased parasympathetic activity is attenuated by eating breakfast
Attenuon LLC - Histidine-proline-rich glycoprotein targets tropomysin to halt angiogenesis
Avidis SA - Protein expression in mutant strains of E. coli BL21(DE3) compared
Baker Heart Research Inst. - Aromatase-deficient mice have reduced blood pressure, baroreflex sensitivity
Bavarian Nordic - Second U.S. contract awarded for smallpox vaccine
Bayer Pharmaceuticals Corporation - Phase II results of BAY 43-9006 reported
Baylor College of Medicine, Houston - Adverse cardiac remodeling occurs through progressive LV wall thinning
Beijing Institute of Radiation Medicine - Analysis of Na+, K+-ATPase beta 2 subunit reported
Bio-Imaging Technologies, Inc. - Letter of intent signed to acquire Heart Core B.V.
BioMedicines, Inc. - Pharmaceutical company change name to Intarcia Therapeutics, Inc.
BioVeris Corporation - Device company receives $1.4M order from U.S. Air Force for analyzers
Biomira, Inc. - FDA grants fast track status for L-BLP25 liposome cancer vaccine
Bradley Pharmaceuticals, Inc. - Dermatology portfolio expanded to include new strength of Zoderm
Brigham & Women's Hospital - Disruption of histone acetyltransferase, MORF, found in benign uterine tumors
Burrill & Co. - G. Steven Burrill to head Biotechnology Advisory Council
California Institute of Technology - Brain circuit may permit scientists to eavesdrop on memory formation
Cancer Research Technology, Ltd. - Licensing deal signed with Vernalis for anticancer program
CardioDynamics - Device firm reports 25th quarter of revenue growth
CardioTech International, Inc. - Worldwide distribution agreement signed for heart-lung machine
Center for Science and Public Policy - Report finds it is safe for pregnant women and infants to eat fish
Chinese Univ. of Hong Kong - Bone densitometry best predicts spinal lumbar BMD/BMC and tibial integral BMD
Circle Group Holdings - Companies to develop commercial version of Lidar and ThraxVac technologies
Cleveland Clinic Foundation - Functional severity is greater in bicuspid than in degenerative tricuspid AS
Cleveland Clinic Foundation - Integrin-linked kinase may inhibit breast cancer metastasis
Coley Pharmaceutical Group - ProMune maker raises $25 million in private financing
Compton Laboratory - Burkholderia pseudomallei secretion mutant had attenuated virulence
Congestive Heart Failure - Stem cell therapy improves heart function after heart attacks
Connetics Corp. - Company inks exclusive European license agreement for Olux
Corazon Technologies Inc. - Demineralizing technology improves aortic valve function in clinical trial
Cornell University - New food intolerance, complex carbohydrate intolerance, identified
Cornell University - The more you have on your plate, the more you overeat, study finds
Cytogen Corporation - Biotechnology company and C.R. Bard Inc. settle patent infringement suit
Dendrite International, Inc. - First Source Integrated Marketing launched to help pharmas reach docs
Derriford Hospital, Devon - Combined femoral and sciatic nerve blocks safe and effective
DiaSys Corp. - Healthcare products company announces new sales management
Dr. M. Fischer Bosch Inst. of Clinical Pharmacol. - CYP3A5 expression guides the way patients respond to statins
Drug Delivery - Long-term use of hepatitis-B drug effective for advanced liver disease
DuPont - CEO says benefits of biotechnology here today, more on the way
DuPont Crop Protection - Agreement gives CompleGen access to a large compound chemical library
Dynamarketing Group, Inc. - Nutritional supplement may help hangovers, ward off alcoholism
Eastman Kodak Company - Milwaukee Brewers to install computed radiography system at Miller Park
Ecole Normale Superieure de Lyon - A novel universal transgene silencing method outpaces existing techniques
Elbit Medical Imaging, Ltd. - InSightec announces $21 million investment
Eli Lilly & Co. - Teriparatide considered a "breakthrough" in treatment of severe osteoporosis
Energy Multi-Vitamin Enhanced Water - New vitamin enhanced water introduced
Escalon Medical Corp. - VuMAX maker reports record revenues and net income for fiscal 2004
FlowMedica, Inc. - Study: Benephit can help protect kidneys during coronary procedures
Fox Chase Cancer Center, Philadelphia - Correction method improves sensitivity of radioactively labeled DNA arrays
Free Radicals - FRS Plus flavonoid formula beverage launches
Frost & Sullivan - Study finds demand for effective prognosis spurs uptake of molecular diagnostics
GNI, Ltd. - Drug-development company announces scientific advisory board
Gothenburg University - Diagnostic utility of 3-D MR angiography determined
Gottingen University - Findings add to the literature on patients with malignant cardiac arrhythmias
Graz University of Technology - Java program facilitates normalization of microarray data
Greystone Associates - Growth in transmucosal drug delivery driven by demographic, healthcare trends
Grifols - Study results of intravenous mixtures system 'mostly positive,' study shows
Hanson Institute, Adelaide - p73 is an ideal target for drugs designed to control angiogenesis
Harvard University - Suppressor of cytokine signaling regulates adipocyte insulin signaling
Harvard University - TRIM5 alpha mediates postentry block to N-tropic murine leukemia viruses
Hokkaido University - Hormones link male rats to attention deficit disorder/hyperactivity disorder
Hopital Huriez, Lille 2 - Quantitative real-time PCR useful for diagnosis of ocular toxoplasmosis
Hormone Replacement Therapy - Study shows hormone pills linked to blood clots in the legs and lungs
Hospital Clinic Porto Alegre - Empyema can be induced by inoculating S. aureus by means of thoracentesis
INSERM U288, Paris - Cizolirtine exerts antihyperalgesic effect in diabetic rats
INSERM, Grenoble - Adrenocorticotropin uses dual mechanisms to control adrenal cortex trophicity
Imaging Diagnostic Systems, Inc. - China's regulatory body approves mammography system
Immunizations - Defense officials play catch up as virus hits recruits
Immunizations - Health officials say there's no flu vaccine shortage in Ohio
Immunizations - Limited flu vaccines available in Oklahoma
Immunizations - MedImmune evaluating whether it can make more inhalable vaccine
Immunizations - Missoula City-County, Montana, health officials stop giving flu shots
In Vivo Medical Diagnostics - Company changes name to reflect new interest in Hall Effect imaging technology
Institut fur Pathologie Bonn-Duisdorf - Neuroendocrine differentiation evaluation recommended in prostate cancer
Institute of Neurology, London - Early brain changes in MS revealed by new MRI techniques
International University of Bremen - Lymphoma risk does not rise with chronic exposure to 50 Hz magnetic fields
Istituto Nazionale Tumori, Milan - Mastectomy may speed disease recurrence in some young women
James Cook University, Townsville - Solution containing adenosine and lidocaine abolished severe arrhythmias
Jefferson Medical College - Fixing anemia doesn't improve survival for head and neck cancer patients
Johns Hopkins University - Molecular analysis depicts the complexity of the human LMX1B gene
Johns Hopkins University - Real-time PCR detects A. phagocytophilum susceptibility to antimicrobials
Johns Hopkins University - Spinal cord nerve cells receive a boost
Karadeniz Tech University - Active SLE complicates pregnancy
Keio University, Tokyo - Mutated BRAF (V599E) is an attractive molecular target for melanoma treatment
Keryx Biopharmaceuticals - Data from KRX-0401 single-agent soft-tissue sarcoma study presented at meeting
Keryx Biopharmaceuticals, Inc. - Biopharmaceutical company files shelf registration statement
Kuwait University, Safat - Seminested PCR-enzyme immunoassay is favorable method for candidemia diagnosis
Kyoto University - Study provides details about the structure of histamine dehydrogenase
Liverpool John Moores University - A fishy solution to animal infection fears
Lund University - Conventional prognostic markers have similar power as microarray profilers
M.D. Anderson Cancer Center - Novel mechanisms account for the synergy of FHIT and p53 in lung cancer tumors
MacroPore Biosurgery, Inc. - Positive results announced from adipose tissue-derived regenerative cells study
Maisonneuve-Rosemont Hospital, Montreal - Candidate retinal disease genes identified
Market Trends - Health Products Research reports on promotion in prescription allergy market
Mashhad University of Medical Sciences - Nasal clearance of different microspheres compared
Massachusetts Biotechnology Council - Biotechnology council names Massachusetts Speaker of the House as president
Massachusetts General Hospital - Methods of pancreatic pseudocyst drainage reviewed
Max Planck Institute for Developmental Biology - Novel transfection method devised for mature hippocampal neurons
Max-Planck Institute of Psychiatry - Stress response reduced by ethanol in sons of alcohol-dependent fathers
Mayo Clinic - Passive transfer of autoimmune autonomic neuropathy demonstrated
Mayo Clinic & Mayo Foundation - Dopamine may be an important regulator of angiogenesis and tumor growth
McMaster University - Hand grip exercise aids blood pressure, carotid artery, endothelial function
Medical Discoveries, Inc. - Biopharmaceutical research company completes $500,000 private equity financing
Medical University of Gdansk - AMP-deaminase from normal and cirrhotic human liver compared
Medical University of South Carolina - Irofulven not active against relapsed/refractory NSCLC
Medical University of Vienna - Operational outcomes of six automated external defibrillators compared
Medtronic, Inc. - Neurostimulation device implanted in study patient for chronic headache
Memory Pharmaceuticals Corp. - Biopharmaceutical company announces appointment of new board member
Merck & Co - Study compares weekly osteoporosis treatment
Merck &. Co., Inc. - Merck withdraws Vioxx based on 3-year data from APPROVe clinical trial
Mie University - Changes in adiponectin expression affect metabolic status in pregnant mice
Montefiore Medical Center - "Sunken chest" corrected by less traumatic, novel surgery
Mylan Laboratories Inc. - Pharmaceutical company granted FDA approval for bromocriptine mesylate ANDA
National Cancer Center Hospital, Chiba - PEI regimen active/well tolerated for sensitive relapsed small-cell lung cancer
National Institute for Medical Research, London - Antibodies to Plasmodium MSP119 form ring structures with antigen
National University, San Luis - Variable cholinergic agent activity in estrous cycle regulates ovarian steroids
NaviCath Ltd. - Remote-control PCIs may aid cardiologists
NeoPharm, Inc. - Drug company director files definitive consent statement to restructure board
NexMed, Inc. - Transdermal treatment company files IND for nail fungal infection treatment
Northwestern University - Cellular surface mechanics dictate complex cell pattern in retina
Northwestern University - No link found between folate intake and the risk of pancreatic cancer
Northwestern University - Psychological adjustment to twins after infertility needs more study
Norwegian American Hospital - William E. Groeper named interim president/CEO of Norwegian American Hospital
Ohio State University - Survivors may have less ability to learn certain tasks
Orebro University Hospital - Hospital-acquired C. difficile infection 1300-fold higher than in community
Oscient Pharmaceuticals Corporation - Pharmaceutical company accelerates FACTIVE sales force expansion
PDI, Inc. - Outsourced marketing services company offers financial, personnel updates
PROKARIA - Genomics develops novel strand-displacing DNA-Polymerase
Paladin Labs Inc. - Pharma company signs marketing agreement for women's health products
Park City Solutions - Palmetto Health Alliance signs agreement to expand laboratory outreach
Peninsula Medical School - Thiazolidinediones do not directly protect pancreatic beta cells
Peninsular Medical School - Information-seeking behaviors of prostate cancer patients' partners studied
Pennington Biomedical Research Cntr. - Basic fibroblast growth factor has rapid bone anabolic effects in OVX rats
Pennsylvania State University - Leg blood vessels adapt with age to allow exercise without fainting
Pharmaprojects - Database tracking pharmaceutical company highlights changing R&D trends
Pro-Pharmaceuticals, Inc. - Pharma company appoints advisory board, retains Hanify & King
ProteoGenix Inc. - Genomics and proteomics selected Bruker Daltonics Inc. as strategic partner
Proteomics - Researchers find soybean plant that lacks allergy-causing protein
Purdue University - Sex-related differences in oral ciprofloxacin disposition not only weight-based
Repligen Corporation - Pharma company initiates clinical trial for obsessive compulsive disorder
Rockefeller University - Dying cells encourage neighbors to grow
STRATEC Biomedical Systems AG - Blood group typing and antibody device development approved by FDA
Sahlgrenska University Hospital - PARP-1 gene knock-out protects male mice from perinatal brain injury
Scripps Research Institute - Pathogenic molecular clone of FIV clade C characterized
Shape Up America - Koop backs nonprofit to make childhood obesity prevention public health priority
Smith & Nephew, Inc. - Atul Minocha named vice president of global marketing by orthopedics firm
Sprint - Virginia's Riverside physicians now using hand-held secure wireless cell devices
St. Jude Children's Hospital - Hematopoietic cells and osteoblasts derived from common BM progenitor cell
St. Jude Medical, Inc. - Medical device company discontinues symmetry bypass aortic product line
Stanford University - New atherosclerosis therapies improve the function of the NO synthase pathway
Stanford University Medical Center - California immunology researchers identify T cell that relieves asthma in mice
Sunnybrook & Women's College - Antioxidants block prostate cancer in transgenic mice
Synbiotics Corporation - Veterinary products corporation restructures debt
Takeda Pharmaceuticals North America - Research-based pharmaceutical submits NDA for investigational sleep drug
Technology University Compiegne, Compiegne Cedex - Fluidized bed bioreactor has potential for extracorporeal liver supply
Tel Aviv University - Lactobacillus GG bacteria ameliorate arthritis in Lewis rats
The Aristotle Corporation - Education, medical supplier acquires science products firm Ginsberg Scientific
Tohoku University - Technique captures flow dynamics produced solely by ventricular expansion
Tongji Medical College - Adeno-associated virus-mediated kallikrein gene therapy prevents cardiac injury
Toshiba America Medical Systems - Research at Beth Israel Deaconess broadens application of multidetector CT
Trakya University Hospital - Pressure-induced tibial pain could be clinical indicator of low bone density
Trans Genic Inc. - Gene-focused company ranked 24th on Deloitte's Fast 50 List in Japan
Transkaryotic Therapies, Inc. - Enzyme-focused company gets $300,000 orphan development grant for Hunter drug
True Health, Inc. - U.K. service, medical equipment provider to hospitals expands sales area
Tufts University - Oral amoxicillin/parenteral penicillin equal in children with severe pneumonia
U.S. Armed Forces Institute of Pathology - Extracellular matrix changes in stented coronary arteries characterized
U.S. Army Med. Research Inst. of Infec. Diseases - Management of laboratory exposures to bioterrorism agents reported
U.S. Centers for Disease Control and Prevention - CDC awards $2.5 million to Emory, UNC to increase cancer screening
U.S. Food & Drug Administration - U.S. FDA launches information campaign to raise risk, benefits awareness of HRT
U.S. National Institutes of Health - Gene essential for A. fumigatus growth but does not contribute to pathogenicity
U.S. National Institutes of Health - Hepatocyte growth factor promotes the metastasis of c-Met positive carcinomas
U.S. National Institutes of Health - International effort makes data freely available to scientists worldwide
U.S. National Institutes of Health - Vision area of the brain finds new work as language processor in blind people
U.S. Tuna Foundation - Foundation seeks to educate consumers that canned tuna is a healthy option
UFR Physiology of the Nutrition - Fraxinus excelsior is hypoglycemic in normal and diabetic rats
Univ. Mediterranee, Marseille - HIV-1 and MLV Gag sufficient to recruit APOBEC3G into virus-like particles
Univ. of California, Davis - Galectin-7 transfection diminishes tumor growth
Univ. of Illinois, Chicago - Clinical trial will see if botanicals can reduce memory loss in menopause
Univ. of Pittsburgh Medical Cntr. - IMRT reduces radiation dose to healthy breast tissue
Universita Vita Salute San Raffaele - Utility of penile implants in era of oral drug treatment reviewed
Universitat Autonoma de Barcelona - C-terminal domain of tetanus heavy chain rescues neurons from apoptosis
University College London - Nogo signaling is a key pathway in nervous system and muscle development
University of Alberta - NIH funds centers to study islet transplantation
University of Amsterdam - Acidic pHi or absence of Nai + loading limit injury
University of Antwerp - Magnesium supplements improve neuropathy in type 1 diabetic patients
University of Auckland - Lactoferrin is a potential therapeutic target in bone disorders
University of Barcelona - Short tilt test with nitroglycerine has advantages for evaluating syncope
University of Bari - Hypo-osmotic swelling test identifies subfertile men likely to cause pregnancy
University of Birmingham - DHEA not recommended for healthy elderly people
University of Cincinnati - Diazoxide activates Akt through the PI3 kinase signaling pathway
University of Cincinnati - Positive force-frequency relationship is related to PLN phosphorylation
University of Cologne - Evidence based treatment of heart failure lowers morbidity and is cost-effective
University of Connecticut - Schedule for Evaluation of Quality of Life validated in diabetic youth
University of Florence - Bilirubin damages surfactant surface tension properties
University of Freiburg - Antiviral antibodies block hepatitis C virus-like particle binding
University of Heidelberg - Rapid effects of aldosterone may participate in pathogenesis of CV disorders
University of Helsinki - KCNJ2 gene mutations should be considered in genetic subclass of LQTS patients
University of Idaho - Culture-independent methods provide insights into infective bacterial species
University of Manitoba - Physical activity guide for older adults improves functional fitness
University of Massachusetts - Cathepsin S appears to play important role in generating peptides
University of Massachusetts - Immortalized microvascular endothelial cells model angiogenesis in vitro
University of Melbourne - Air rather than oxygen recommended for newborns requiring ventilation
University of Melbourne - Ventilating babies with air, rather than pure oxygen, could reduce mortality
University of Michigan - SH2-B gene disruption causes insulin resistance and glucose intolerance
University of Minnesota - Abnormal motor function persists after recovery from perinatal Cu deficiency
University of Minnesota - Plasma phytoestrogens unaltered by postmenopausal women's probiotic consumption
University of Missouri - High-fat meal attenuates benefits of exercise session
University of Munich - Efficacy of automated external defibrillators determined in rail stations
University of New South Wales - Effect of sPLA2 deposition on bacterial contact lens adhesion determined
University of North Carolina - Expensive new meds increase drug expenditures in the state Medicaid program
University of Pennsylania - Grant will fund initiative to help understand genes' effects on medications
University of Pittsburgh - Autoimmune conditions share overlapping genetically controlled pathways
University of Rochester Medical Center - The anti-VEGFR2 antibody DC101 potentiates the effects of tumor radiotherapy
University of Sao Paulo - Genetics/lifestyle influence protective effect for developing atrophic gastritis
University of Saskatchewan - Streptococcus dysgalactiae proteins protect against bovine mastitis
University of South Florida - Novel alpha7 nAChR subunit isoform identified
University of Southern California - Bladder cancer bank will be effective tool in marker development
University of Southern California - Smoker airflow obstruction severity correlates with Pneumocystis colonization
University of Surrey - Low-fat diet impedes vitamin E absorption
University of Sussex - Putative bZIP domain of Epstein-Barr virus EBNA 3C analyzed
University of Sydney - High glucose upregulates PPAR-gamma and has anti-inflammatory effects
University of Tampere - Atherosclerotic lesions in LAD appear to depend on amount of alcohol consumption
University of Texas Medical Branch - RNA viruses alter vector host range, resulting in potential disease emergence
University of Utah - Genes reveal modern & archaic humans made contact
University of Utah - Good for the ozone - neurotoxic for workers
University of Utrecht - Postoperative health status measures compared
University of Vermont - Estrogen plus progestin associated with increased risk of venous thrombosis
University of Virginia - Local anesthetics inhibit thromboxane A2 signaling in K562 cells
University of Washington - Pegylated interferon may cause vision disorders in chronic hepatitis C patients
University of Wisconsin - Reduced adiposity by desaturase deficiency is PPAR-independent
University of Zurich - Concurrent infections with vector-borne pathogens caused fatal hemolytic anemia
University of the Basque Country - Enkephalin-degrading enzymes in human semen reviewed
Valentis, Inc. - Results in phase 2 clinical trial of claudication arterial drug announced
Varian Medical Systems - Image-guided radiation device installed at radiotherapy clinic in Switzerland
Varian Medical Systems, Inc. - Chris Hanna appointed vice president of newly formed oncology information unit
Wake Forest Univ. Medical Center - Soy could be good for the heart and bones of premenopausal women
Washington Group International, Inc. - Pfizer awards architectural, engineering services contract for Michigan projects
Washington University - UV-A-responsive genes identified in lens epithelial cells
Weizmann Institute of Science - Animal model for PCOS developed
Welch Allyn - Medical products manufacturer launches wireless rapid response software system
World Health Organization - Program focuses on stopping 'invisible epidemic' of maternal deaths in poor areas
Yale University - Nonpathogenic, live, viral vaccine vectors responses characterized
Yamanouchi Pharmaceutical Co. - FibroGen to license erythropoietic small molecule in development for anemia
diaDexus, Inc. - Web site exposes connection between inflammation and coronary heart disease
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