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U.S. Centers for Disease Control & Prevention

MIF expression in P. falciparum-infected placentas characterized

Published in Biotech Law Weekly, August 5th, 2005

Scientists have characterized macrophage migration inhibitory factor (MIF) expression in Plasmodium falciparum-infected placentas.

According to recent research from the United States, Kenya, Thailand, and Switzerland, "Previously, we have shown that macrophage migration inhibitory factor (MIF) was highly elevated in the placental intervillous blood (IVB) of Plasmodium falciparum-infected women. Here, we compared the expression of MIF in placental tissues obtained from P. falciparum-infected and -uninfected women. Immunoperoxidase staining showed a consistent pattern of MIF expression in syncytiotrophoblasts, extravillous trophoblasts, IVB...

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