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St. Vincent's Hospital, Darlinghurst

Neurokinin-1 receptor studied, immunopositive arterial cells identified

Published in Biotech Law Weekly, September 2nd, 2005

Recent research from Australia has reported on the identification of a subset of cells immunopositive for neurokinin-1 receptor (NK-1R).

"In the adventitia of large arteries, dendritic cells are located between nerve fibers, some of which contain substance P. The aim of the present study was to examine whether NK-1R was expressed by dendritic cells in the arterial wall," wrote Y.V. Bobryshev and colleagues, St. Vincent's Hospital.

"Parallel sections of aortic and carotid artery segments were immunostained with anti-NK-1R and cell-type-specific antibodies. Dendritic cells in the arterial wall expressed NK-1R, albeit at a low level.

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