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Biotech Law Weekly

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California Birth Defects Monitoring Program, Berkeley



 NPPA appears to be a good candidate gene for conotruncal defects



November 4th, 2005

Researchers have investigated the risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes.

According to investigators in the United States, "Investigating possible genetic polymorphisms and gene-environment interactions in the etiology of human conotruncal defects is a prudent research approach. In [our] study we explore gene-only and gene-environment effects of 32 single nucleotide polymorphisms (SNPs) on conotruncal defect risks."

G.M. Shaw and colleagues of the California Birth Defects Monitoring Program explained, "The genes bearing these SNPs participate in one...


Source: Biotech Law Weekly (2005-11-04)

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