Biotech Law Weekly

Oregon State University - Hydrologic conditions are associated with mosquito populations and disease transmission

Organon Pharmaceuticals USA Inc. - Pharma company appoints Terrence Moore as vice president

Ortec International, Inc. - Tissue engineering company announces $3.3 million private placement

POZEN, Inc. - Trexima NDA accepted for review by U.S. Food and Drug Administration

Panjab University, Chandigarh -  E. coli K13 diphtheria toxoid conjugate was immunogenic against pyelonephritis

Pasteur Institute of Iran - Beta-TCP/HDPE is a biocompatible and nontoxic bone biomaterial, study indicates

Personnel - Crowell & Moring, LLP, adds new partner to healthcare group

Pfizer - New survey shows many women take home pregnancy tests too early to be accurate

PharmIdeas Research & Consulting Inc. - Avonex is cost-effective for delaying MS onset after single demyelinating event

Pharsight Corporation - Drug development software services company releases WinNonlin Validation Suite

Post Graduate Institute of Medical Education & Research, Chandigarh - Radiotherapy produces satisfactory results for patients unable to receive chemotherapy

Praecis Pharmacueticals Incorporated - Pharma company to sell corporate headquarters for $51.2 million

Princess Margaret Hospital, Toronto - Glycoconjugation deemed feasible delivery technique for camptothecin

Proteus - Patent granted for gene shuffling technology

Queen's University, Kingston - N-acylation of glucosamine modulates chondrocyte growth, PG synthesis, and gene expression

Regina Elena Institute for Cancer Research, Rome - Epirubicin, cisplatin and docetaxel were combined to treat metastatic gastric cancer

Roche Diagnostics - LightCycler 480 Real-Time PCR System introduced for genomics research

Ruhr-University Bochum - Radiographic progression in infliximab patients show inhibition of structural damage

Sapporo Medical University - Novel scoring system predicts prolonged hypotension after carotid stenting

SciClone Pharmaceuticals - Pharma company names Dr. Israel Rios as chief medical officer

SciGen Ltd - Biopharma company signs distribution agreement for hepatitis B vaccine in China

Shimane University - Hypoxia inducible factor-1 alpha is upregulated in regenerating livers after hepatectomy

Showa General Hospital, Tokyo - Technique reliably measures blood flow volume and artery diameter

Sigma-Aldrich - Diverse collection of drug-like screening compounds for drug discovery now available

Socratic Technologies, Inc. - Survey finds one-third of Americans belong to gyms or health clubs

Solbec - Carter resigns from pharma company; Graeme-Howie appointed executive director

Sontra Medical Corporation - Results from transdermal vaccination safety and feasibility studies reported

SourceOne Healthcare Technologies, Inc. - Medical imaging systems distributor signs agreement with GPO HealthTrust

Southwest Foundation for Biomedical Research - Researchers discover gene on chromosome 15 that regulates inflammation

St. George Hospital, London - HOXA9 expression may increase with age in human hemopoietic cells

St. Vincent's Hospital, Dublin - Study declares new markers of ovarian cancer be judged against CA125

Standard & Poor's - Third-quarter results show positive momentum in U.S. not-for-profit healthcare

Stanford University - Modern imaging modalities used to assess resectability of pancreatic cancer

Starpharma - Development of VivaGel accelerated with US$20M funding from U.S. National Institutes of Health

State University of Ghent - Bovine herpesvirus-1 inhibits sperm-zona binding by interacting with spermatozoa

Substance Abuse & Mental Health Services Administration - Public health agency awards $7.2 million in grants for mental health programs

Surface Logix - Clinical trial finds SLx-2101 safe, well tolerated and effective

Sysmex America, Inc. - Clinical lab systems maker receives 2005 HPIS Best in Class Award for hematology

TREK Diagnostic Systems - Diagnostics company receives U.S. FDA clearance on Tigecycline (Tygacil)

Taipei Medical University - Econazole induces G₀ /G₁ cell cycle arrest and caspase 8-independent apoptotic signaling

Tanzania National Institute of Medical Research - Micronutrient supplementation and zinc do not have significant effects on TB culture conversion

Targeted Genetics Corporation - Next clinical trial of drug injected into inflamed arthritic joints initiated

Technion Israel Institute of Technology, Haifa - Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages

Tel Aviv University - WBC count is marker for stratification of ischemic cerebrovascular disease

Temple University, Philadelphia - p73 interacts with HIV-1 Tat in astrocytic cells and prevents its acetylation on lysine 28

Texas Children's Hospital, Houston - Expression profiles of osteosarcoma predicted response to chemotherapy

The Medicines Company - Maker of products for acute care names Melvin Spigelman, MD, to board of directors

ThermoGenesis Corp. - Company provides master file to U.S. FDA for system to harvest mononuclear cells

Thoraxcenter - Self-contained MRI catheter allows identification of vulnerable coronary plaque

Tm Bioscience - Genetic reagents tests for cystic fibrosis maker signs agreement to supply assay

Tulane National Primate Research Center, Covington - Simian immunodeficiency virus disrupts extended lengths of the blood-brain barrier

U.S. Centers for Disease Control & Prevention - CDCP smoke alarm installation and fire safety program saves lives

U.S. Centers for Disease Control & Prevention - Leptospirosis found in patients presenting with dengue-like illness

U.S. Centers for Disease Control & Prevention - Progressive coal workers' pneumoconiosis indicates gap in preventive measures

U.S. Centers for Disease Control & Prevention - Total and percent free PSA levels among U.S. men reported

U.S. Department of Veterans Affairs - U.S. VA's medication system aims to reduce inaccurate administration

U.S. Food & Drug Administration - Continuous virginiamycin exposure needed for streptogramin-resistant E. faecium in chickens

U.S. Food & Drug Administration - IL-4 receptor is promising target for advanced ovarian cancer therapy

Universata, Inc. - Information exchange option for medical records software announced

Universita Politecnica delle Marche, Ancona - Anemia used as prognostic factor in patients undergoing resection for lung cancers

University College London - Interleukin-10 receptor blockade may augment therapy targeting hepatitis C

University Hospital Gasthuisberg, Louvain - QRS shortening in tetralogy of Fallot is related with better exercise performance

University Hospital of Angers - Value of systematic central neck dissection called into question

University Hospital of Jena - Coping strategies for families of elderly cancer patients described

University Hospital, Maastricht - Adenosine induces vasodilatation in the human hypertensive kidney

University Hospital, Munster - Incor LVAD has comparable results, some advantages over other devices

University Hospital, Strasbourg - Loss of flexibility may be early feature of cardiac metabolic dysregulation

University de Beira Interior, Covilha - Improved recovery of a fusion protein promises reliable and cheap serodiagnostic tests

University of Amsterdam - Biliary drainage procedure proposed for palliative management of hilar cholangiocarcinoma

University of Amsterdam - Endocrine late effects occurred from multi-modality treatment of neuroblastoma

University of Arkansas for Medical Sciences - Review aims to guide preventive approaches to atrial fibrillation

University of Athens - Mediterranean diet is associated with total antioxidant capacity

University of Athens - Thyroxin-induced cardioprotection is a direct effect of thyroid hormone

University of Bologna - New edition of TNM staging system for hepatocellular carcinoma endorsed

University of Bologna - Nutritional status modulates oxidative injury in rat fatty liver exposed to ischemia reperfusion

University of British Columbia - Requiring help injecting predicts HIV infection incident among intravenous drug users

University of Buenos Aires - Nitroxyl is an inhibitor of human platelet function

University of California, Los Angeles - Findings illuminate how antiarrhythmic drugs terminate fibrillation

University of California, Los Angeles - Researchers report gene's role in the human embryo implantation process

University of California, San Diego - Pancreastatin is elevated in diabetes and inhibits glucose uptake

University of California, San Francisco - Accuracy of mammography is similar among white, Chinese, and Filipino women

University of California, San Francisco - Alternative cysteine metabolism and glutathione production pathway proposed in C. albicans

University of California, San Francisco - Cinacalcet reduced risk of parathyroidectomy, fracture, and CV events in ESRD patients

University of California, San Francisco - Non-RD1 gene cluster required for Mycobacterium tuberculosis Snm secretion

University of California, San Francisco - Rituximab added to CHOP does not improve clinical outcome of HIV-associated non-Hodgkin lymphoma

University of Chicago - Infarction in intact organs viewed by high-resolution 3-D optical imaging

University of Chicago Hospitals - TEE examinations are associated with low risk of esophagogastric trauma

University of Chicago Medical Center - High-risk African American women may benefit from genetic testing

University of Colorado - Shank2E binds NaPi cotransporter at the apical membrane of proximal tubule cells

University of Dusseldorf - Hepatitis B vaccine programs in Germany should be extended to include susceptible populations

University of Freiburg - New assay protocol for determining histone deacetylase activity described

University of Gottingen - NT-proBNP or troponin testing: good first step to identify risk with pulmonary embolisms patients

University of Hong Kong - Lamivudine improves renal status in patients with hepatitis B-associated kidney disease

University of Illinois - Fluorescent confocal microscopy facilitates study of prostate pH levels

University of Illinois - Monocarboxylate transporter implicated in fatty acid transport in human intestine

University of Iowa - Transperitoneal approach advised when abundant fatty tissues surrounds kidney

University of Kentucky - Recommendations for cancer caregiving outlined

University of Kentucky - Zinc may be key component in protective PPAR signaling during atherosclerosis

University of Leeds -  Herpesvirus saimiri-based vectors have been used to target liver diseases

University of Liege - Decoy-mediated inhibition of activator protein-1 is effective asthma therapy

University of Liverpool - Bed rest for hypertension during pregnancy is not backed by strong evidence

University of Ljubljana - Nerve growth factor-induced histamine release from mast cells involves a signaling pathway

University of Lodz - Lipopolysaccharide interaction with thiol may be the basis of oxidative stress in blood platelets

University of London - Bacterial substrate coating improves colonic targeting of single-unit tablets

University of Louisville - Heart morphology and function are sensitive to marginal copper deficiency

University of Michigan - Magnetic resonance spectroscopy differentiates high and low grade brain tumors

University of Missouri - GDP-mannose dehydrogenase inactivation in P. aeruginosa reveals critical active site loop

University of Navarra - Researchers identify location of cellular prion protein in a rat brain model

University of Pennsylvania - Amyloid beta proteins promote oxidative lipid membrane damage

University of Perugia - Use of Ga-67-SPECT/CT with a hybrid system aided clinical management of lymphoma

University of Rochester - ImmunoCyt endorsed as sensitive test for detecting bladder cancer

University of Rochester Medical Center - U.S. Department of Defense funds research on how nicotine impairs bone healing

University of Rome La Sapienza - Protein is undetectable in patients with no response to hepatitis C therapy

University of Rouen - Hapten that hydrolyzes nerve agent has been developed

University of Sao Paulo - ESR2 polymorphism is an independent risk marker for premature CAD

University of Southern California - Adjuvant radiotherapy increases survival among women with p53 gene alterations

University of Southern California - Neuroscientist Antonio Damasio receives Prince of Asturias prize

University of Sydney - Pemetrexed and vinorelbine used to treat patients with non-small cell lung cancer

University of Texas SW Medical Center, Dallas - RIM1 alpha PDZ domain forms a complex with an ELKS1 b C-terminal peptide

University of Texas SW Medical Center, Dallas - UVB-induced immunosuppression due to augmented dectin-2 expression in Langerhans cells

University of Toronto - Phospholipase C gamma recruitment to erythropoietin receptor may activate ERK pathway

University of Tsukuba, Ibaraki - Near infrared fluorescence can image cerebrospinal fluid space and movement

University of Turin - Group care improves quality of life and knowledge in type 1 diabetes

University of Utah - Plasma cell neoplasms reviewed

University of Utah - Scientists find molecular structure relevant to cell growth and cancer

University of Utrecht - Drug-resistant HIV-1 variants most commonly seen in patients infected with subtype B virus

University of Virginia - Virginia health system wins renewal of $6.2 million grant for Crohn disease research

University of Virginia Health System - Type 1 collagen stent-grafts biocompatible in rabbit small-diameter vessels

University of Washington - Bariatric surgery-related deaths among Medicare patients higher than previously thought

University of Washington - Low salivary levels of antimicrobial peptides may contribute to dental caries susceptibility

University of Washington - Researcher develops nutrient density score

University of Western Australia - Management of menopausal symptoms in cancer patients requires multidisciplinary approach

VA Palo Alto Health Care System - Latin Americans with chronic hepatitis C are less likely to initiate or continue therapy

VA San Diego Healthcare Systems - Up-regulation of adipocyte differentiation-related protein helps preserve insulin action

Varberg Hospital, Gothenburg - Even moderate BP increase is associated with increased myocardial repolarization lability

Virginia Commonwealth University - Mitochondria have a crucial role in aspirin-induced apoptosis in human gastric epithelial cells

Viventia Biotech Inc. - Biotech company changes name of armed antibody when used for bladder cancer

Wakayama University - Dietary protein, fat and beta-carotene levels affect beta-carotene absorption in rats

Wake Forest University, Winston-Salem - Parathyroidectomy was associated with decreased calcification in dialysis patients

Walter & Eliza Hall Institute, Melbourne - Structure of PfGAPDH from P. falciparum is determined

Wayne State University, Detroit - Prenatal exposure to alcohol may cause visual problems in infants

West Pharmaceutical Services Inc. - Don McMillan named division president by medical devices manufacturing company

Wolfson Wellcome Biomedical Laboratories -  Schistosoma haematobium interacts with S. guineensis in Cameroon

Zonare Medical Systems, Inc. - Sacred Heart Medical Center acquires Zone Sonography technology

eResearchTechnology, Inc. - ECG core laboratory completes XML process under Mortara Certified Partner program