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University of Rome La Sapienza

Protein is undetectable in patients with no response to hepatitis C therapy

Published in Biotech Law Weekly, November 11th, 2005

Protein is undetectable in patients with no response to hepatitis C therapy.

"Recent studies have suggested that phosphorylated signal transducers and activators of transcription 1 (STAT1) plays an important role in interferon (IFN)-mediated biological functions, including antiviral activity. Moreover, it has been demonstrated that suppressors of the cytokine signal 1 (SOCS1) negatively regulates IFN activities," researchers in Italy report.

A. Aceti and colleagues, University of Rome La Sapienza performed research "to investigate the involvement of phospho-STAT1 in the response to IFN-alpha therapy in patients with chronic hepatitis C and to...

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