Biotech Law Weekly

Northwestern University, Chicago - Researchers' findings advance Botulinum Toxin research

Norwegian Radium Hospital, Oslo - 67-kd LR used for differential cancer diagnosis

Norwegian Radium Hospital, Oslo - Arrayed primer extension detects breast and ovarian carcinoma mutants

OSI Pharmaceuticals, Inc. - EMEA to issue updated positive opinion and recommendation of Macugen for AMD

OccuLogix, Inc. - Medical therapies company establishes scientific advisory board

Ohio State University - Conjugated linoleic acid may limit VEGF-A expression in breast tumors

Ohio State University - Envelope is major viral determinant of cellular transformation tropism of HTLV-1 and -2

Ohio State University - Mutations in determinants of HTLV-1 Env SU do not prevent viral replication

Okayama University - Gene therapy enhances angiogenesis in brains with cerebral hypoperfusion

Oncolytics Biotech Inc. - Biotech company announces CAN$16.48 million private placement

Oregon Health & Science University - Protein loss contributes to initiation of ovarian follicular assembly

Oregon Health & Science University - Relation between breastfeeding and reduced risk of childhood leukemia needs further study

Osmangazi University, Eskisehir - Findings in angiology provide new insights

Palm Healthcare Foundation (PHF) - Foundation awards $230,000 in scholarships to Palm Beach County, Florida, nursing students

Par Pharmaceutical Companies, Inc. - Pharmaceutical company begins shipment of generic Adoxa

Pediatric Services of America, Inc. - Pediatric home health company announces revenue growth of 6% to $172,200,000

Pfizer Inc - Pharma company increases dividend 26% to 24 cents per share for the first quarter of 2006

PharmaLinkFHI - Duke University Health System awards contract to follow patients impacted by hydraulic fluid

Pharmion Corp. - Encouraging data on Vidaza presented at American Society of Hematology meeting

ProMetic Biosciences Inc. - PBI-1402 phase I trial is complete and shows positive results

ProMetic Life Sciences Inc. - Biopharma company names Christian Frayssignes CEO of animal sciences

Queens University of Belfast - Coronary microvascular endothelial cell growth regulates gene expression

Queensland Institute for Medical Research - G-CSF analogs eradicate NKT cell-dependent leukemia after stem cell mobilization

Queensland Institute of Medical Research - No association found between Alu insertion polymorphism and endometriosis

Quest Diagnostics Incorporated - Diagnostics company presents data on soon-to-be introduced assay for hematologic diseases

Research & Markets, Ltd. - Cell therapy report added to Research & Markets' offerings

Robert Koch Institute, Berlin - Naive resident peritoneal macrophages kill Listeria monocytogenes-infected hepatocytes

Royal Marsden Hospital, Sutton - Use of PET/CT in oncology reviewed

Rush University, Chicago - BoNTA, a serotype of botulinum toxin, has fewer side effects and a longer duration of effect than BoNTB

Rush University, Chicago - Sleep disturbances are more common at beginning and end of menstrual cycle

SAIC Frederick Inc. - HIV virions without the nucleocapsid still contain significant amounts of RNA

SIGA Technologies, Inc. - U.S. FDA accepts investigational new drug application for smallpox drug, grants fast-track status

Saba - Novartis Farmaceutica selects online training program

San Antonio Breast Cancer Symposium - Symposium highlights that genetic differences may determine breast cancer risk

Schering-Plough Corporation - Study shows Noxafil reduces invasive fungal infections in high-risk chemotherapy patients

Schizophrenia - Combination clozapine-ziprasidone reduces the required daily dose of clozapine

Spectrum Pharmaceuticals, Inc. - Rolling NDA submission begins for satraplatin in hormone refractory prostate cancer

St. James University Hospital, Oxford - Mesenchymal stem cells have potential for a wide range of tissue engineering applications

St. John's Mercy Medical Center, Saint Louis - Obesity is associated with a wide variety of ECG abnormalities

Stanford University - High-resolution real-time spiral MRI guidance effective in rabbit model

Stanford University - The osteogenic potential of adipose-derived mesenchymal cells is maintained with aging

Stanford University Medical Center - Research shows brain is an important part of pain control

Stavanger University Hospital - Researchers report details of new studies and findings in the area of prognostics

Sungkyunkwan University, Seoul - Characteristics of synchronous adenocarcinoma and MALT lymphoma analyzed

Sungkyunkwan University, Seoul - Radioiodine tracks the pharmacokinetics of angiostatin

Swedish National Institute of Environmental Medicine - Study finds strong link between diabetes and increased risk of colon and rectal cancer

Tata Memorial Hospital, Maharashtra - Total thyroidectomy and use of radioactive iodine advised for thyroid cancer

Tea Council of the U.S.A. - Research suggests drinking tea may decrease risk of ovarian cancer by 46%

Technical University of Munich - Guidelines for follow-up after polypectomy based on size, location, and number of polyps

Technoflex S.A. - Joint venture formed to make sterile-filled injectable drugs in New York

Tokyo Medical & Dental University - Nucleotide variations in SERPINB genes are associated with prostate cancer

Tottori University - Oral geranylgeranylacetone pretreatment improves rat survival after LPS injection

TriPath Imaging, Inc. - Study demonstrates correlation between biomarker reactivity and breast cancer recurrence risk

Tufts University, Medford - Micro- and nanospheres used for DNA encapsulation are characterized

Tulane University, New Orleans - Review focuses on plaque-imaging techniques in CVD prevention

U.S. Centers for Disease Control & Prevention - Alveolar macrophages and neutrophils play roles in limiting virus replication

U.S. Centers for Disease Control & Prevention - Data advance knowledge in diagnostics research

U.S. Centers for Disease Control & Prevention - Method to detect phthalate metabolites in human saliva is developed

U.S. Department of Health & Human Services - National PSA campaign encourages hurricane survivors to use mental health services

U.S. Food & Drug Administration - Agency advises of risk of birth defects with Paxil

U.S. Food & Drug Administration - Vaccination schedules affect excretion of oral poliovirus vaccine strains

U.S. National Cancer Institute - Malignant effusions provided fibronectin for metastasis

U.S. National Institutes of Health - Abnormal results in combination tests allow for improved prediction of cancer risk

Ullevaal University Hospital, Oslo - New findings in thrombosis described

Uniformed Service University of Health Science, Bethesda - Viral detection described in cell lines and postmortem brain tissue

Universita di Palermo - Prognostic and predictive significance of the p53 mutation assessed

University of Alabama - Risk factors leading to hypercholesterolemia and colorectal cancer studied

University of Alberta - Findings describe new data in Pulmonary Medicine research

University of Amsterdam - Article reviews ezetimibe/simvastatin (INEGY) treatment of hyperlipidemia

University of Athens - Squamous and nonsquamous cancers respond alike to platinum-based combination chemotherapy

University of Auckland - Glycosulfatase activity causes changes in vaginal flora linked to bacterial vaginosis

University of Bari - Researchers provide details of new studies and findings in the area of oncology

University of Bologna - Interleukin-6 gene polymorphism is an age-dependent MI risk factor

University of California, Los Angeles - Quality improvement program targeting provider organizations fails to increase screening rates

University of California, Los Angeles - Retroviral suicide gene therapy achieves long-term survival in glioma

University of California, Los Angeles - Variations in patterns of HAART adherence associated with behavior and age

University of California, San Francisco - Lower levels of apolipoprotein E influence Alzheimer disease

University of Cambridge - MAdCAM-1 is needed for diabetes development mediated by the T cell clone, BDC-2^.5

University of Cardiff Wales - Expression of Com-1 correlated with prognosis of breast cancer patients

University of Delaware - Perlecan knockdown diminishes prostate tumor vascularity and growth

University of Florence - Tissue kallikrein reduction changes angiogenesis patterns in systemic sclerosis

University of Florida - Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity

University of Frankfurt Klinikum - Research in SARS provides new insights

University of Giessen - A severe, undiagnosed disease can be the cause of erectile dysfunction

University of Gottingen - HIV-tat-mediated Bcl-X_L delivery protects retinal cells in optic neuritis

University of Halle Wittenberg - Appearance of necrosis in head and neck cancer patients indicates need for cure

University of Helsinki - Outbreak-associated norovirus identified in drinking water by RT-PCR

University of Hong Kong - Responses to advanced cancer in Chinese-Australians reviewed

University of Iowa Hospital & Clinic - Unrelated cord blood transplant successful in children with Shwachman-Diamond syndrome

University of Kentucky - Ecdysone receptor function is influenced by ultraspiracle/retinoid X receptor

University of Kentucky - Novel group of genes regulates drug susceptibility in breast cancer cells

University of Kiel - Biomechanical factors regulate angiogenesis in the bone and joint system

University of Leicester - Researchers describe findings in Prostate Cancer studies

University of Libre Bruxelles, Brussels - High glucose or diabetic milieu did not induce IL-1 beta synthesis or NF-kappa B activation

University of Liverpool - Introduction of rotavirus vaccines is expected to substantially reduce mortality

University of Lodz - Polymorphisms of the BRCA2 gene associated with breast cancer

University of London Imperial College - Adult bone marrow-derived stem cells may be key to myocardial repair

University of London Royal Veterinary College - Deer antler regeneration may be stem cell based

University of Manchester - Low SHBG is a potential marker for the metabolic syndrome in different ethnic groups

University of Maryland - Recent findings in gynecology provide new insights

University of Massachusetts - Short-term exercise training improved insulin action

University of Minnesota - Pancreas transplants can provide glucose control in type 2 diabetes mellitus recipients

University of Montreal - Studies advance knowledge in statins research

University of New South Wales - Modified auditory brainstem implant effective as extraocular retinal prosthesis in cats

University of North Carolina - Calmodulin binding region exists in ryanodine receptor channel

University of North Carolina - Interplay occurs in IFN-gamma-inducible MHC-II gene expression

University of Paris 07 - Macrophage-produced granulysin contributes to antimycobacterial defense

University of Pecs - Report reviews pharmacotherapy of childhood and adolescent obesity

University of Pittsburgh - DNA vaccine ameliorates type 1 diabetes in NOD mice

University of Pittsburgh - Plasmalemmal vesicle associated protein-1 highlights brain tumor angiogenesis

University of Roma Tor Vergata - Diabetes and atherosclerosis share vascular homeostasis and glucose metabolism

University of Rome Tor Vergata - Percutaneous kyphoplasty effective for treatment of intractable pain due to vertebral collapse

University of South Florida - Incidence of abdominal wall metastasis complicating PEG tube placement evaluated

University of South Florida - Studies add new findings to Diabetes Pathogenesis body of knowledge

University of Southern Denmark - Women and elderly cancer patients were less likely to receive formal terminal diagnosis

University of Texas Health Science Center, San Antonio - NAFLD markers ALT and AST-to-ALT ratio predict metabolic syndrome independently

University of Texas Medical Branch, Galveston -  Staphylococcus aureus in thermal injury is controlled via effector cell induction

University of Tokyo - B-catenin signaling negatively regulates retinal-neurite extension

University of Utrecht Medical Center - Olanzapine reduces physical activity in hyperactive patients

University of Utrecht Medical Center - Precoagulation minimizes blood loss in pig model

University of Vermont - Properties of cardiac muscle contribute to gender-related incidence and mortality of heart failure

University of Virginia - Optimum management of patients with low-grade gliomas investigated

University of Warwick, Coventry - Antigenic drift in weekly flu incidence rate is highly nonuniform

University of Washington - Reports describe recent advances in immunology research

University of Washington - Resistin is not associated with insulin sensitivity or the metabolic syndrome

University of Zurich - Glioma cell growth inhibited by siRNA targeting of growth factor

VU University, Amsterdam - Patient profile, not dialyzer type, is linked to endothelial dysfunction

Vanderbilt University School of Medicine, Nashville - Genetic variants may predict virologic failure and/or emergence of drug-resistant HIV

Walter & Eliza Hall Inst. for Medical Research, Parkville - Study of merozoite surfaces provides insight into erythrocyte invasion, anti-parasite immunity

Weston Park Hospital, Sheffield - Reduced dose capecitabine deemed effective treatment in metastatic breast cancer

Wuhan General Hospital of Guangzhou Command - Recent findings illuminate research in Drug Delivery

Yale University School of Medicine - Differences seen in characteristics of Black women seeking binge eating disorder therapy

Yokohama City University, Kanagawa - Angiotensin II receptor blockers staunch prostate cancer proliferation

Yonsei University - Telomerase activity detected by real-time TRAP assay in body fluids