Biotech Law Weekly

Massachusetts General Hospital - Link between common deletion polymorphisms can be evaluated in whole-genome association studies

Massachusetts General Hospital - NT-proBNP testing is valuable for diagnosis, short-term prognosis in dyspneic patients

Massachusetts General Hospital - Research reports a validated clinical, biochemical score for diagnosis of acute heart failure

Massachusetts General Hospital - Women with major depression at risk of relapse during pregnancy without medication

Max-Planck Institute of Immunobiology, Freiburg - p53 deficiency rescues apoptosis and differentiation of multiple cell types

Max-Planck Institute of Psychiatry, Munich - Shh down-regulation implicated in pathogenesis of pituitary adenomas

Mayo Clinic - High levels of HtrA1 protein may be biomarker of preeclampsia

Mayo Clinic - Population-based study finds no link between prior myocardial infarction and dementia

McMaster Clinic Hamilton Health Science - Report announces the MICHELANGELO OASIS-5 trial evaluating fondaparinux

Medical Research Council, London - Dextrin sulphate 4% appears to be well tolerated in low-risk HIV-negative women

Memorial Sloan-Kettering Cancer Center, New York - Research add new data to melanoma vaccines body of knowledge

Mercy Medical Center, Springfield - Tenofovir drug interactions increase risk for acute renal failure

Mexico National Institute of Public Health - Feasible to effectively treat same number of patients at same or lower cost per patient

Miyazaki University - TNF-alpha contributes to induction of an effective immune response against HIV-1

Monash University, Clayton - Vascular or mixed hemodynamic profile measured during lab stress may be CVD risk marker

Musculoskeletal Clinical Regulatory Advisors, LLC - Pharma consulting company names Glenn A. Stiegman, III as vice president

National Cancer Center, Goyang - Dihydroartemisinin enhanced radiosensitivity of human glioma cells

National Cheng Kung University, Tainan - Modified PLGA scaffolds increase osteoblast adhesion and proliferation

National University of Singapore - Hybrid scaffold/cell construct repairs high-load-bearing osteochondral defects

Neurobiological Technologies, Inc. - Neurobiological Technologies receives $1.4 million quarterly royalty payment related to Memantine

New York Eye & Ear Infirmary - Computerized motion analysis superior to subjective assessment of facial synkinesis

NewLink Genetics Corporation - Researchers' work adds to melanoma vaccines body of knowledge

Nippon Dental University of Tokyo - SIP1 expression could be used to prognosticate oral squamous cell carcinomas

Ohio State University - Alemtuzumab induces caspase-independent cell death in lymphocytic leukemia cells

Olgahospital, Stuttgart - Role of adjuvant therapies to treat grossly-resected synovial sarcoma discussed

Oregon Health & Science University - Ototoxicity in children receiving platinum chemotherapy may impact academic and social development

Oswaldo Cruz Institute, Rio de Janeiro - DNA vaccine protects mice against Dengue type 2 virus

Ovarian Cancer - Influence of surgeon experience and hospital volume on ovarian cancer outcome studied

PainCare Holdings, Inc. - Rehab and pain management company acquires controlling stake in Amphora, LLC

Pediatrics - Children's asthma care improves on state health insurance program

Pennsylvania Cancer Alliance - Tobacco settlement aids research, returns substantial dividends to Pennsylvania's economy

PhytoMedical Technologies, Inc. - Independent 3 year study shows cinnamon can relieve diabetes by lowering blood sugar levels

Postgraduate School of Gastroenterology, Milan - A model accurately predicts severe fibrosis or cirrhosis in chronic hepatitis C

Primagen Holding B.V.Conta - Molecular tests company licenses newly discovered coronavirus CoV-NL63 to bioMerieux

Primary Children's Medical Center, Salt Lake City - Use of frozen sections in pediatric and adolescent surgical pathology examined

Progen Industries - Phosphosulfomannan angiogenesis inhibitor analogues act variably

Protedyne Corporation - Laboratory automation provider appoints Fran Tuttle as president and CEO

Protemix Corporation - Biopharma company elects Jean-Pierre Millon as chairman of the board

Proteome Systems Limited - Medical technology company signs agreement to develop tuberculosis biomarkers

Provectus Pharmaceuticals, Inc. - Provectus receives fourth pharmaceutical patent for anticancer agents

RWTH Aachen University - Cytokine integration enhances the angiogenic potential of collagen matrices during wound repair

Regina Apostolorum Hospital - Percutaneous laser ablation used to treat hepatocellular cancer

Research & Markets - Market report says personalized medicine and molecular diagnostics to show robust growth

Research & Markets - Report finds every 1% increase in generic dispensing cuts pharmaceutical expenditures by 0.6%

Research & Markets - U.S. has the largest over-the-counter drug market in the world, according to new report

Rockefeller University, New York - Leptin secretion a strong predictor of long-term body fat accrual on a high-fat diet

Roskamp Institute, Sarasota - Genomic regulation in microglia perturbs genes relevant to Alzheimer disease

Royal Free and University College Medical School, London - Researchers report details of new studies and findings in the area of diagnostics

Royal Melbourne Hospital, Parkville - Functional mammary gland generated from a single stem cell

Royal Victoria Hospital - Spermatogonia stem cells and somatic environment in the testis are involved in the aging process

STERIS Corporation - Healthcare, life sciences company reports Q3 2006 revenue increase of 5% to $287.5 million

Schering, AG - U.S. FDA clarifies status of YAZ PMDD application

Schering-Plough - U.S. FDA grants fast track designation to investigational oral HCV protease inhibitor

Schering-Plough Corp. - European Medicines Agency CHMP recommends approval of Remicade for ulcerative colitis

Seoul National University - Caveolin-1 expression in pleomorphic carcinoma correlated with poor prognosis

Socket Communications, Inc. - Crosslink Orthopaedics selects vendors to deliver real-time inventory visibility

St. Bartholomew's Hospital, London - TransDermal Delivery System beta suitable for local anesthesia in venipuncture

St. George's Vaccine Institute, London - Reports describe recent advances in meningitis vaccines research

Standard Management Corporation - Pharma company announces intention to raise $40 million in new capital

Stanford University - Systole is significantly prolonged, diastole correspondingly shortened in children with HF

Starkey Laboratories - High-powered behind-the-ear and open-fit hybrid hearing device introduced

Stoke Mandeville Hospital, Ayelsbury - Cataracts can cause false positives on frequency doubling perimetry screening for glaucoma

Swedish Institute for Infectious Disease Control - Researchers provide details of new studies and findings in the area of HIV/AIDS vaccines

Synova Healthcare, Inc. - New look at HRT highlights the value of starting soon after menopause

Technical University of Dresden - Bone chips are suitable for culturing high numbers of differentiated osteoblast-like cells

Temple University School of Medicine, Philadelphia - Electrocardiographic manifestations of noncoronary heart disease are focus of review

Teratology Society - Obese women suffer more pregnancy complications, babies at higher birth defect risk

Teva Pharmaceutical Industries Ltd. - Israel-based generic drug company sets pricing of $1.25 billion of convertible debentures

Tottori University - New findings in the area of neurology detailed

Translational Genomics Research Institute - Partners form joint Center for Systems and Computational Biology

TriPath Imaging, Inc. - Oncology diagnostics-focused company reports 2005 revenues increased 26% to $68.5 million

Tufts University, Boston - Polyelectrolyte multilayer film coating suitable for oral devices

Tufts University, Boston - Subcutaneous microsphere injection effective for sustained clonazepam release

Tyco International Ltd. - Healthcare products company reports Q1 2006 earnings of 39 cents per share

U.S. Centers for Disease Control & Prevention - Depictions of substance use in reality television send mixed messages

U.S. Food & Drug Administration - Agency approves new treatment for gastrointestinal and kidney cancer

U.S. Food & Drug Administration - Microbiologic surrogate end points in otitis media trials are evaluated

U.S. National Academies - Global effort needed to foresee, prevent potential misuse of advances in life sciences

U.S. National Cancer Institute - Interferon gamma-inducible protein 10 inhibits tumor angiogenesis

U.S. National Cancer Institute - Large population-based study examines risk for AML following Hodgkin lymphoma

U.S. National Institute of Diabetes & Digestive & Kidney Diseases - Study identifies candidate genes for obesity susceptibility

U.S. National Institute of Neurological Disorders & Stroke - Monocytes foster vascular repair following brain injury

U.S. National Institute on Deafness & Other Communication Disorders - STAT3 activation is differentially regulated in squamous cell carcinomas

U.S. National Institutes of Health - Adverse CV influence of low testosterone may be mediated via vascular structure, function

U.S. VA Medical Center, Cincinnati - Acetazolamide improves central sleep apnea in heart failure

Uganda Virus Research Institute - Prevention counseling reduces HIV transmission among uninfected partners

Uniformed Services University of the Health Sciences, Bethesda - Antipolysaccharide Ig responses to S. pneumoniae depend on B-cell receptor signaling

Unilens Vision Inc. - Contact lens developer launches aspheric, single-vision, 2-week disposable soft lens

University Hospital Basel - I-MIBG scanning improves pheochromocytoma test accuracy

University Hospital Grosshadern, Munich - Nucleophosmin gene mutations predicted favorable prognosis in leukemia

University Hospital of Freiburg - Contrast ultrasound perfusion imaging is a novel diagnostic method in peripheral arterial disease

University Hospital of Ulm - Mutant nucleophosmin predicted favorable prognosis in acute myeloid leukemia

University Hospital, Lausanne - Increased NT-proBNP plasma levels were found in diabetics with vascular complications

University Hospitals of the Ruprecht-Karl-University of Heidelberg - Intramedullary nailing effective for unstable forearm fractures in children

University Medical Center, Utrecht - Routine auscultation is valuable for pre-op detection of valvular heart disease

University of Aachen - Open colon surgery for colon carcinomas deemed not problematic

University of Amsterdam - Lewis X component in human milk inhibits HIV-1 transfer to CD4+ T lymphocytes

University of Antwerp - Gene mutation discovered that causes rare form of inherited nerve disorder

University of Barcelona - Noninvasive ventilation improves outcome of acute cardiogenic pulmonary edema

University of Belgrade - Effect of acute crowding stress on rat brown adipose tissue metabolic function was examined

University of Bergen - Pregnancy hormones may influence rate of women with postbirth breast cancer

University of British Columbia - Nitric oxide scavenger AMD6221 augments cardiac response to noradrenaline in rat model

University of Buenos Aires - Researchers report details of new studies and findings in the area of Brucellosis vaccines

University of California, Berkeley - Dendritic cells were targeted using pH-responsive microparticle vaccine carriers

University of California, Los Angeles - Imiquimod enhances dendritic cell survival and promotes T-cell priming

University of California, San Diego - Mouse model identifies method to reduce migration of white blood cells in autoimmune disease

University of California, San Diego - Neutralizing antibody responses drive HIV-1 Env evolution during recent infection

University of California, San Francisco - Extended-release clarithromycin well tolerated and bioequivalent to IR formulation

University of California, San Francisco - New drug inhibited in vitro bladder cancer migration and invasion

University of Cape Town - Three independent mechanisms for exercise-associated hyponatremia were identified

University of Erlangen-Nurnberg - Studies add new findings to cardiology body of knowledge

University of Frankfurt - COX mechanisms play a role in maintaining pain hypersensitivity

University of Frankfurt - Low molecular weight heparin may improve prognosis of cancer patients

University of Geneva - In vitro tests support feasibility of transdermal iontophoretic triptorelin delivery

University of Georgia - Infectious bronchitis variant viruses circulate in commercial poultry

University of Hong Kong - Avian influenza virus infections in humans are focus of review

University of Houston - AII-induced Na⁺, K⁺-ATPase activation in proximal tubules may lead to hypertension

University of Illinois - Hypertension-associated nucleotide polymorphism did not diminish treatment efficacy with irbesartan

University of Illinois - Retinal thickness mapping monitors choroidal neovascularization in treated eyes

University of Khartoum - Filter-paper blood samples are useful for sero-epidemiology in developing countries

University of Kitakyushu - Hepatocyte culture system developed

University of Leicester - Treatment with budesonide does not affect pregnancy outcome

University of Lodz - Data advance knowledge in breast cancer research

University of Michigan - Adenovirus expressing B. anthracis antigen protects against anthrax

University of Michigan - Docking studies shed light on folate binding in cancer therapy

University of Michigan Medical Center - Study compared mapping criteria for postinfarction ventricular tachycardia

University of Milan - HIV-1 K103N mutation after HAART withdrawal has little impact on viral fitness

University of Milan - Researchers' findings advance breast cancer research

University of Missouri - The role of insulin resistance in the cardiometabolic syndrome is reviewed

University of Natural Resources & Applied Life Sciences, Vienna - Method is developed for generation of monoclonal antibody against SNEV protein

University of Nottingham - Barrett esophagus and gastroesophageal reflux disease linked to higher mortality rates

University of Ottawa - TSH stimulates IL-6 release from 3T3-L1 adipocytes through cAMP-protein kinase A pathway

University of Patras - Expression of licensing factors, Cdt1 and Geminin in human colon cancer examined

University of Pennsylvania - Review examines complications of biological therapy for inflammatory bowel diseases

University of Perugia - Effects of increased plasma ghrelin levels on metabolism and endocrine system are studied

University of Queensland - Cervical cancer vaccine being altered to treat genital warts

University of Queensland - Recent studies add new data to diagnostics research

University of Queensland - Researchers provide details of new studies and findings in the area of neuroscience

University of Rochester - Valcyte did not protect against CMV infection in liver transplant recipients

University of Sao Paulo - Estrogen replacement therapy was not found to enhance cardiopulmonary response to exercise

University of Sheffield - HRQOL concerns over use of dexamethasone in pediatric leukemia addressed

University of Southern California - Novel device enables ab interno approach to trabeculectomy

University of Texas SW Medical Center, Dallas - Findings advance knowledge in genetics & genomics research

University of Texas SW Medical Center, Dallas - Gut protein protects against infection, intestinal breakdown

University of Texas SW Medical Center, Dallas - Unique patient profile characterizes HF with preserved systolic function

University of Tubingen - Findings describe new data in transplant medicine research

University of Utah - Silicon contamination may promote calcification of hydrophilic acrylic IOLs

University of Utrecht Medical Centre - Direct targeting of modified tumor cells to Fc gamma RI triggers cytotoxicity

University of Virginia - Mindfulness-based stress reduction better for mood improvement, massage better for pain

University of Western Ontario - MT-II brain gene expression is primary candidate for ethanol preference control in mice

Vanderbilt University Medical Center, Nashville - Media coverage on flu effective in influencing parents to vaccinate their children

Vical Incorporated - Enrollment opened in phase 2 trial of DNA vaccine against cytomegalovirus

Vion Pharmaceuticals, Inc. - Plans for phase 2 trial of anticancer agent in elderly poor-risk AML patients announced

Wake Forest University Baptist Medical Center, Winston-Salem - Some masks used in children's asthma treatment not effective

Washington University, St. Louis - Studies describe new findings in prostate cancer research

Wayne State University, Detroit - New findings in the area of drug resistance described

XenoPort, Inc. - Pharmaceutical company reports Q4 05 revenues of $437,000, down from $2.6 million in Q4 04

Xi'an Jiaotong University - CD58 expression is related to HBV infection severity and degree of liver damage

Xradia, Inc. - Biotech company receives $1.4 million NIH grant to develop nano-scale X-ray microscope

Yale University - Protein related to vaccinia virus methyltransferase is involved in Trypanosoma cap 4 modification

Zimmer Holdings, Inc. - Orthopedic surgical products company reports Q4 2005 net sales up 6% to $848 million

eFoodSafety.com, Inc. - EPA registration for germicidal product received by food safety products company

eGene Inc. - Maker of genetic analyzer systems seeking North American distribution partners

sanofi-aventis - Campaign launched raise awareness of childhood cancer in emerging countries