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Abbott Laboratories
Smooth muscle cell genes not known to be regulated by vitamin D analogs are identified
June 23rd, 2006
A recent study identified genes not previously known to be regulated by VDR, providing insight into understanding the role of VDR on regulating smooth muscle cell growth, thrombogenicity, fibrinolysis and endothelial regeneration. Researchers in the United States report, "Vitamin D analogs provide survival benefit for chronic kidney disease patients with cardiovascular complications. Activation of smooth muscle cells plays a role in cardiovascular diseases. It is not known how Vitamin D analogs modulate gene expression in smooth muscle cells." J.R. Wu-Wong and colleagues at Abbott Laboratories explained, "In this study, DNA micro-array technology was...
Source: Biotech Law Weekly (2006-06-23)
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