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Aarhus University
Lambda IFNs expressed in response to most viruses and are active against select viruses
June 23rd, 2006
Lambda interferons are expressed in response to most viruses and are active against select viruses. According to recent research from Denmark, "Type III interferons (IFNs) (interleukin-28/29 or lambda interferon [IFN-lambda]) are cytokines with IFN-like activities. Here we show that several classes of viruses induce expression of IFN-lambda 1 and -lambda2/3 in similar patterns." "The IFN-lambdas were-unlike alpha/beta interferon (IFN-alpha/beta)-induced directly by stimulation with IFN-alpha or -lambda, thus identifying type III IFNs as IFN-stimulated genes. "In vitro assays revealed that IFN-lambdas have appreciable antiviral...
Source: Biotech Law Weekly (2006-06-23)
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