Vall d'Hebron University Hospital, Barcelona, Spain
Phase Ib ventricular arrhythmias are not suppressed by Gd3+ infusion into ischemic region
Published in Biotech Law Weekly, July 28th, 2006
According to researchers in Spain, "Increased mechanical tension in the ischemic region during acute coronary occlusion might favor the occurrence of phase Ib ventricular arrhythmias. We aimed to investigate whether intracoronary administration of Gd3+, a stretch-activated channel blocker, into the ischemic zone reduces the incidence of these arrhythmias."
"In thiopental-anesthetized, open-chest pigs, the left anterior descending coronary artery (LAD) was ligated for 45 or 48 min," wrote J.A....
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Source: Biotech Law Weekly (2006-07-28)
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