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Biotech Law Weekly

Susan Hasty, Publisher

Table of Contents . . . November 17th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Biotech Law Weekly | Other Publications

Alcohol Use - The media rarely notes when alcohol plays a role in violent crimes and accidents

Anthrax Vaccine - Safety advocates oppose Pentagon's return to mandatory anthrax vaccination of military personnel

Awards - Debiopharm and Ecole Polytechnique Federale honour Dr. Eduward Batlle with life sciences award

Business & Finance - Caraco Pharmaceutical reports net sales rise 43%

Business & Finance - Enzo Biochem reports results for fiscal 2006 and fourth quarter

Business & Finance - Watson certifies substantial compliance with FTC second request

Business Update - Santarus licenses OTC rights to lower dose immediate-release omeprazole products to Schering

Business Update - Willow Laboratories participates in U.S. Department of Labor's drug-free work week

Collaborations - Merck KgaA, Glenmark Pharmaceuticals to collaborate on DPPIV inhibitor for type 2 diabetes

Dental Research - Danish agency makes statement about tooth whitening products

Finance - Cyberkinetics closes $10 million private placement

Finance - MedicalCV, Inc. announces $2.5 million private financing

Gene Therapy Policy - Policymaking process in Japan for gene therapy is appraised

Legal Issues - Align Technology and OrthoClear complete definitive agreement

Legal Issues - Ambry Genetics agrees to pay Roche royalties due for licensing of PCR technology

Legal Issues - Court rules in favor of Guidant over Medtronic

Legal Issues - Enzo Biochem reports favorable Markman ruling in federal court upholding key patent claim terms

Legal Issues - Insmed sues Tercica for false advertising

Legal Issues - MedCom USA subsidiary Card Activation Technologies initiates patent infringement lawsuits

Legal Issues - National Digital Medical Archive and i3 Archive sued for patent infringement by InSite One

Legal Issues - U.S. District Court grants Mylan's motion to dismiss '909 patent

Legal Issues - U.S. District Court upholds Risperdal (risperidone) patent

Mergers & Acquisitions - AnorMED and Genzyme reach agreement on acquisition

Patents - Austrian Patent Office rules in Pfizer's favor

Patents - HemoCue says it will continue to enforce its patented technology

Patents - Purdue Pharma, Teva Pharmaceuticals sign consent judgment ending OxyContin tablets patent lawsuit

Product Safety - Counterfeit test strips discovered in United States

Acute Care - Satisfied patients are also vulnerable patients

Acute Myeloid Leukemia - Presence of FLT3 mutations does not impair stem cell mobilization

Acute Radiation Syndrome - Hollis-Eden: Neumune mitigates ARS and healthcare-associated infections

Addiction Medicine - Beck Depression Inventory predicts drug use severity during opiate agonist maintenance therapy

Adipose Tissue - Angiotensin type 1 receptor antagonists induce adipogenesis through PPAR-gamma activation

Adipose Tissue - Prostacyclin improves transcoronary myocardial delivery of adipose tissue-derived stromal cells

Advanced Squamous Cell Carcinoma - Taxotere receives U.S. FDA approval for treatment for patients with head and neck cancer

Adverse Drug Reaction - Systolic blood pressure shows significant increase with rofecoxib vs. celecoxib therapy

Aesthetic Medicine - Isolagen and U.S. FDA reach agreement on phase III protocol design for wrinkle therapy

Age-Related Macular Degeneration - Age-related macular degeneration-linked hemorrhage shows seasonal variation

Age-Related Macular Degeneration - Choroidal neovascularization is differentiated with autofluorescence patterns

Age-Related Macular Degeneration - Patients with age-related macular degeneration have a prominent polymorphism

Alcohol Use - Moderate alcohol consumption may be associated with a lower risk of heart attack among men

Alcohol Use - Moderate drinking may boost memory

Alcohol Use - Moderate, daily consumption of alcohol beverages can play a role in a healthful lifestyle

Alcohol Use - Naltrexone and disulfiram offer no advantage for treating alcohol abuse and psychotic disorder

Allergies Vaccines - Researchers from University of Western Australia describe findings in allergies vaccines

Allergy & Immunology - Activated NKT cells increase dendritic cell migration and enhance skin CD8+ T cell responses

Allergy & Immunology - Allergens from olive pollen exhibit activity after expression in transgenic Arabidopsis

Allergy & Immunology - Allergic asthma is not modulated by ADAM33

Allergy & Immunology - Allergic disease takes heavy toll on children's health and quality of life

Allergy & Immunology - Exposure to sunlight could reduce asthma

Allergy & Immunology - Gonarthritis synovial predictors of successful treatment are determined

Allergy & Immunology - Gonarthritis treatment of radiation synovectomy has harmful effects on human cartilage

Allergy & Immunology - New lab mice pave way for novel studies of human infection

Allergy & Immunology - Structure and function of the long pentraxin PTX3 glycosidic moiety examined

Allergy & Immunology - U.S. FDA approves Allegra Oral Suspension for seasonal pediatric allergies, idiopathic urticaria

Alzheimer Disease - Computer-based games enhance mental function in patients with Alzheimer

Alzheimer Disease - Lysosome-associated membrane protein 1 is involved in pathogenesis of Alzheimer disease

Alzheimer Disease - Martek's vegetarian-source docosahexaenoic acid selected for U.S. NIH-funded Alzheimer study

Alzheimer Disease - Memory Pharmaceuticals reports U.S. FDA status of trial on MEM 3454 in Alzheimer disease

Alzheimer Disease - Naturally occurring enzyme can break down a key part of Alzheimer plaques

Alzheimer Disease - Regression-stage senile plaques in natural course of Alzheimer disease are described

Alzheimer Disease - U.S. FDA approves Eisai's Aricept to treat severe Alzheimer disease

Alzheimer Disease Vaccine - Fv antibodies against Abeta fragment inhibit Abeta toxicity

Amyotrophic Lateral Sclerosis - Avicena completes patient enrollment for ALS-08 phase II clinical trial

Amyotrophic Lateral Sclerosis - Cyberkinetics' BrainGate System enables thought-driven computer control for ALS patient in trial

Anesthesia - Anesthetic considerations for radical prostatectomy outlined

Anesthesia - High-frequency oscillatory ventilation effects on cerebral circulation are studied

Anesthesia - Propofol concentration is increased with positive end-expiratory pressure

Angiogenesis - Research from Harvard University, Division of Engineering and Applied Sciences provides new data about angiogenesis

Angiology - An overweight population referred for dyspnea evaluation showed high-risk SPECT scans

Angiology - Elective intra-aortic balloon pumping in unprotected left main stenting is studied

Angiology - End-to-end aortic arch reconstruction is feasible without myocardial ischemia

Angiology - Endothelial-specific heat shock protein is essential for angiogenesis and development

Angiology - Internal mammary artery graft patency is assessed using TTDE

Angiology - MRI allows detection of aortic dissection complications in long-term follow-up

Angiology - Pulsatile pump is compared to combined CP and intra-aortic balloon pump

Angiology - Regional arterial stiffness decreased after single-leg resistance exercise

Angiology - TNF-alpha-induced activation of coronary arterial endothelial cells is attenuated by resveratrol

Angiology - Transient myocardial ischemia patients show increased pulse wave velocity

Animal Research - Female animals choose a mate based on substance as well as show

Anthrax - Medarex, PharmAthene report positive phase 1 results in anthrax therapeutic Valortim trial

Anthrax Vaccine - Vical demonstrates novel method of predicting DNA vaccine effectiveness

Antibacterial Agents - Intravascular catheter-related bacteremia is successfully treated with ALT

Antibacterial Agents - Levofloxacin is used as antibiotic prophylaxis before liver surgery

Antibiotics - Data presented on Factive Tablets short-course antibiotic therapy in patients with co-morbidities

Antimicrobial Resistance - Beta-lactam exposure increases risk of metallo-beta-lactamase-producing Pseudomonas infection

Antimicrobial Resistance - Mutations in topoisomerase targets produce fluoroquinolone resistance in Salmonella typhi

Antimicrobial Resistance - Role of hospital stay and antibiotics on Pseudomonas in hospitalized patients is examined

Antioxidants - Cinnamon extract provides antioxidant support for people with impaired fasting blood sugar

Apoptosis - Apoptosis genes regulated by Wnt/beta-catenin pathway identified

Apoptosis - Beta-cell death is regulated by nuclear factor-KB

Apoptosis - Early apoptotic genes targeted in batch and fed-batch CHO cell cultures

Apoptosis - Ewing sarcoma cell apoptosis induced by arsenic trioxide

Apoptosis - Skeletal muscle of spontaneously HTN rats shows DNA fragmentation, altered apoptotic protein levels

Arthritis - Array BioPharma reports ARRY-438162 meets initial clinical objectives

Asthma - Bronchodilator response to salbutamol inhaled via different devices is studied

Asthma - Experts and policymakers demand changes to current approach to asthma management

Asthma - U.S. FDA accepts for review Critical Therapeutics' NDA for controlled-release zileuton

Asthma Vaccines - Study data from Roche update understanding of asthma vaccines

Astrocytoma - Angiogenesis has prognostic significance in adult astrocytomas

Astronomy - Hubble yields direct proof of stellar sorting in globular clusters

Atherosclerosis - Atherosclerotic plaques feature interplay between angiogenesis and inflammation

Atherosclerosis Vaccines - Investigators at Cedars-Sinai Medical Center, Department of Medicine release new data on atherosclerosis vaccines

Atrial Fibrillation - CryoCath enrolls first patient in U.S. atrial fibrillation trial

Autism Research - Imaging technique shows how anatomical differences in brains of people with autism affect brain function

Autoimmune Diseases - Autoimmune hepatitis and human leucocyte antigen are genetically associated

Avian Influenza - Medco study shows Americans stockpiled Tamiflu over fears of bird flu pandemic

Avian Influenza - sanofi pasteur H5N1 pre-pandemic vaccine neutralizes additional H5N1 virus

Avian Influenza - Study identifies North American wild bird species that could transmit bird flu

Awards - Cedars-Sinai Medical Center director receives genetics award

Awards - Cross Country Healthcare's chief nursing officer awarded 2006 R. Louise McManus Medal

Awards - Deloitte names etrials one of the fastest growing companies for the second consecutive year

Awards - MedAvant named one of Georgia's fastest growing technology companies

Awards - Prana cofounding scientist, Colin Masters, receives international prize in biomedical research

Bacillus Calmette-Guerin Vaccination - Favorable BCG vaccination response related to lower child mortality

Bacillus Genetic & Genomics -  Bacillus cereus isolates linked to fatal pneumonias harbor B. anthracis virulence genes

Bacteriology - Cell wall of pneumonia bacteria can cause fatal heart damage; antibiotic therapy may contribute to damage

Benign Prostatic Hyperplasia - Demand for enlarged prostate treatments expected to rise sharply

Biofilms - Data on biofilms published by researchers at University of New South Wales

Biological Chemistry - New findings from University of Erlangen, Center of Molecular Medicine in the area of biological chemistry published

Biomedical Engineering - Findings from University of Washington, Department of Bioengineering advance knowledge in biomedical engineering

Biomedical Engineering - Recent findings in biomedical engineering described by researchers from University of Sao Paulo, Department of Restorative Dentistry

Biomedical Engineering - Report summarizes biomedical engineering study findings from Harvard University, Department of Biostatistics

Biomedical Engineering - Reports from Sree Chitra Tirunal Institute for Medical Sciences and Technology advance knowledge in biomedical engineering

Biomedical Engineering - Research on biomedical engineering reported by scientists at Tel-Aviv University, Department of Periodontology

Biomedical Engineering - Research on biomedical engineering reported by scientists at University of Tokyo, Department of Materials Engineering

Biomedical Engineering - Research reports from University of Technology, Department of Electrical Engineering provide new insights into biomedical engineering

Biomedical Engineering - Research reports on biomedical engineering from Oregon Institute of Technology provide new insights

Biomedical Engineering - Researchers from Flinders University detail new studies and findings in the area of biomedical engineering

Biomedical Engineering - Researchers from Stony Brook University, Department of Biomedical Engineering describe findings in biomedical engineering

Biomedical Engineering - Researchers from University of Cincinnati, Department of Biomedical Engineering detail findings in biomedical engineering

Biomedical Engineering - Scientists at University Hospital publish research in biomedical engineering

Biomedical Engineering - Studies from Chang-Gung University, Department of Neurosurgery reveal new findings on biomedical engineering

Biomedical Engineering - Studies from Sichuan University add new findings in the area of biomedical engineering

Biomedical Engineering - Studies in the area of biomedical engineering reported from University of Michigan, Department of Biomedical Engineering

Biomedical Engineering - Study results from Fraunhofer Institute for Biomedical Engineering update understanding of biomedical engineering

Birth Weight - Health-related quality of life among very low birthweight children requires monitoring

Bladder Cancer - Bladder cancer managed and diagnosed by fluorescence cystoscopy

Bladder Cancer - Bladder cancer possibly prognosticated by lymphovascular invasion

Bladder Cancer - Macrophage cytotoxicity against bladder cancer cells involves cytokines

Bladder Cancer - Recurrent bladder cancer predicted by multi-target fluorescence in situ hybridization

Blood Banking - Platelet preparation methods compared

Blood Glucose - Blood glucose meter focuses on essentials of testing

Blood Glucose - HbA1c provides glycemia information, but does not reflect short-term fluctuations

Blood Glucose - NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism

Blood Products - Poised for rapid expansion, world blood market exceeds $20 billion

Blood Safety - Human herpesvirus 8 can be transmitted by blood transfusion

Blood Safety - U.S. National Institutes of Health awards grant for clinical trial of bacterial test

Blood Transfusion - Safe Blood for Africa conducts west/central African donor recruitment workshop

Bovine Coronavirus Outbreaks - Bovine coronavirus detected in dysentery outbreak in Cuba

Brain Aneurysms - Boston Scientific launches trial to study endovascular treatment of brain aneurysms

Brain Cancer - Brain tumor diagnostics aided by amide proton transfer imaging

Brain Cancer - Glioma-produced extracellular matrix influences brain tumor tropism of neural stem cells

Brain Cancer - Single brain metastases are treated with resection and brachytherapy

Brain Stem Tumors - Brain stem tumor prognostic factors and surgical outcome described

Brain Tumors - Intracranial ependymomas show limited effects of cyclooxygenase-2 expression

Breast Cancer - Breast cancer lesions are detected with small peptide Tc-99m-NC100692

Breast Cancer - Breast cancer linked to metastasis-associated protein 2

Breast Cancer - Breast cancer patients did not benefit from maintenance paclitaxel in first-line chemotherapy

Breast Cancer - Breast cancer risk linked to BRCA1 mutation and osteopontin overexpression

Breast Cancer - Breast cancer surgical candidates selected by combination of USPIO-enhanced MR and FDG-PET

Breast Cancer - Breast cancer treated by butyroyloxymethyl-diethyl phosphate and doxorubicin

Breast Cancer - Breast cancer's inverse association with benign ovarian cysts remains unexplained

Breast Cancer - Distant recurrence of breast cancer predicted by lymph node status

Breast Cancer - Lawrence Berkeley reports tissue geometry plays crucial role in breast cell invasion

Breast Cancer - Mastopathic fibroadenoma of the breast subclassified

Breast Cancer - Orion Genomics announces collaboration to validate clinical utility of breast cancer screening test

Breast Cancer - Study finds race affects African American survival of breast cancer

Breast Cancer - Vector-activated dendritic cell injection and chemotherapy suppresses breast cancer

Breast Fibroadenoma - Breast fibroadenoma diagnosed by fine needle aspiration

Breast Reconstruction - East Cooper Regional Medical Center surgeons perform innovative breast reconstruction

Buruli Ulcer Risk - Buruli ulcer risk higher in Bacillus Calmette-Guerin-vaccinated persons in Benin

Business & Finance - Advancis Pharmaceutical provides update on Keflex launch, finances

Business & Finance - avVaa World Health Care reports loss of $0.02 per share

Business & Finance - Biopure receives notice of Nasdaq listing requirements

Business & Finance - Cangene reports 6.4% increase in revenues

Business & Finance - Cryo-Cell International reports third quarter 2006 results

Business & Finance - Encision reports second fiscal quarter results

Business & Finance - Encore Medical announces preliminary results for third quarter of 2006

Business & Finance - Endo Pharmaceuticals reports third quarter 2006 financial results

Business & Finance - Hercules and Portola announce a $20 million financing agreement

Business Update - Abaxis announces U.S. FDA action on status

Business Update - Acorda Therapeutics expands Zanaflex capsules sales force to 65

Business Update - Adherex regains all rights to ADH-1

Business Update - Advair HFA Inhalation Aerosol launched

Business Update - AdvanDx announces launch of PNA FISH and Evigene products in Canada for in vitro diagnostic use

Business Update - AgION Technologies antimicrobial technology used in keyboard and computer mouse

Business Update - Align Technology launches ClinAdvisor to simplify case assessment

Business Update - Amgen Foundation launches $25 million undergraduate research program

Business Update - Aperio partners with SeongKohn Traders to bring digital pathology to South Korea

Business Update - Aptuit deploys Clinicopia labeling solution at clinical packaging and logistic facilities

Business Update - Aspect Medical Systems launches new products at anesthesiologists' meeting

Business Update - Auxilium Pharmaceuticals to reallocate resources to AA4500 development

Business Update - Bayer appoints independent investigator to review Trasylol study issues

Business Update - BioAdvance launches process for life sciences businesses seeking investment

Business Update - BioMimetic receives U.S. FDA approval, expanding manufacturing capacity

Business Update - Bliss Virtual Slide Workstation allows complete brain slice slides to be scanned

Business Update - Blood Systems Laboratories selects Abbott Prism System for automated blood screening

Business Update - Boston Scientific now has two drug-eluting stents with European approval

Business Update - Bradley responds to reports from proxy advisory firms

Business Update - Breakthrough reported for Sangui oxygen carriers

Business Update - CAD Sciences excels in competition at Stanford University

Business Update - Cambridge Biostability passes first milestone in partnership with DynPort

Business Update - CardioWest temporary Total Artificial Heart adopted by top transplant centers

Business Update - Cargill delivers "Driving Heart Health With Consumers" presentation at Health Ingredients Europe

Business Update - Catholic Healthcare Partners selects Siemens as sole-source provider of NextGen solutions

Business Update - Cejka Search leaders to share expertise on physician retention and healthcare career development

Business Update - CheckUps signs supply agreement with Bioject for needle-free injections in its walk-in clinics

Business Update - Chicago Prostate Cancer Center reaches global milestone using IsoRay's Cesium-131 isotope

Business Update - China Biopharma retains OTC Financial Network for comprehensive investor relations campaign

Business Update - China Health Holding issues shares to chief executive officer in consideration of previous loans

Business Update - Cognis presents holistic product concepts for the wellness market at SEPAWA Congress

Business Update - CogState launches world's first real-time cognitive data monitoring system

Business Update - Compugen discloses status of in silico-discovered therapeutic candidates

Business Update - CompuMed announces new contract to provide remote ECG screening to Mississippi correctional sites

Business Update - CordLife Indonesia officially launched

Business Update - CoreValve's third-generation ReValving System for aortic valve replacement reaches milestone

Business Update - Corindus unveils CorPath remote controlled angioplasty system at cardiovascular symposium

Business Update - Coronado Industries edges closer toward marketing their PNT glaucoma treatment in China

Business Update - Covalent signs $8.2 million in contracts for multinational studies to treat influenza

Business Update - Critical Care enters First Nation's health care market

Business Update - CryoCor PMA amendment delayed

Business Update - Crystal Research Associates issues Executive Informational Overview on Medgenics

Business Update - CSMG Technologies completes duct and vessel sealer prototype

Business Update - D-Pharm to join NeuroNE Network of Excellence

Business Update - Delta Health Technologies announces strategic partnership with CellTrak Technologies

Business Update - Derma Sciences announces renewal of sales agreement with largest customer in Canada

Business Update - Detroit Receiving offers Michigan's first hospital-based hyperbaric wound care program

Business Update - DJO renews supply contract with Premier Purchasing Partners for additional three-year term

Business Update - DNAPrint Pharmaceuticals completes the development of a third assay for PT-401

Business Update - Dow Neurobiology Laboratories extends their MetaCore licenses from GeneGo

Business Update - Duke University Health System joins with Draeger Medical to implement Innovian Anesthesia solution

Business Update - DuPont introduces Biosecurity Kits for businesses seeking assistance with disease preparedness

Business Update - Eaton Laboratories issues corrected record date for spinoff of subsidiary

Business Update - Elekta to install the first Leksell Gamma Knife in Kuwait

Business Update - Emminens chooses Netsize as mobile partner in delivering services to aid diabetics

Business Update - Endo Pharmaceuticals comments on Lidoderm

Business Update - Environmental Tectonics announces its hyperbaric chamber is part of global industry training

Business Update - Enzo Biochem acquires license to six key RNA amplification patents

Business Update - Eskitis Institute enhanced by flexible compound processing solution

Business Update - Europe's largest cancer treatment centre selects digital radiography system from Kodak

Business Update - ExonHit seeks to identify blood diagnostic for atherosclerosis

Business Update - General Technologies provides fourth progress report on ImmunAid for HIV positive patients

Business Update - Hamilton Medical launches Autopilot for hospital ventilators

Business Update - Iconix adds Heiner Dreismann, PhD, to board, changes name

Business Update - IQ Micro to enter high growth diabetes market

Business Update - Medical Services International begins marketing plan for HIV test kits in South Africa

Business Update - Merck and Lundbeck update submission plans for U.S. FDA approval of insomnia drug gaboxadol

Business Update - Micro-Virology Labs announces availability of disinfectant tests for biopharma industry

Business Update - Miraculins successfully detects prostate cancer primary protein biomarker using immunoassay

Business Update - MyMD launches innovative free, online live chat program with health care professionals

Business Update - OSI systems unit SpaceLabs Healthcare launches anesthesia system in North American market

Business Update - Pfizer announces third quarter revenues

Business Update - Quintiles opens central laboratory in Mumbai, India

Business Update - Renowned ophthalmologist Richard Lindstrom joins Refractec board of directors

Business Update - Roche's nine-month sales hit record high

Business Update - Serono, Newron sign agreement to develop and market safinamide for cognitive disorders

Business Update - Siemens goes 3D with new stereo medical imaging display

Business Update - Sigma-Aldrich introduces neural stem cell expansion medium

Business Update - Spectral Diagnostics and Estor expand relationship to distribute EAA sepsis test in Italy

Business Update - SRS Medical expands bicoastal operations

Business Update - ThermoGenesis commences scale-up of AutoXpress production

Business Update - Top five pharma firms purchase large-scale genetic analysis system from Illumina

Business Update - Tourtellotte Solutions unveils supply chain simulator for the pharmaceutical industry

Business Update - TranSenda participates in the BioIT Alliance BioMarkers project

Business Update - Vaso Active ships product to A&P and ShopRite

Business Update - Virco launches method to establish new HIV-1 resistance profiles for protease inhibitors

Business Update - VirTra Systems receives new simulator order from Mexico

Business Update - Zynex's two-fold increase in September orders demonstrates impact of sales force

Cancer Gene Therapy - Antitumor effect enhanced by vaccination with telomerase reverse transcriptase modified tumor cell

Cancer Gene Therapy - Cancer cell gene expression changes following human papillomavirus integration

Cancer Gene Therapy - Controlled suicide gene system selectively kills human umbilical vein endothelial cells

Cancer Gene Therapy - Hepatocarcinoma gene therapy inhibiting NF-kappa B results in apoptosis

Cancer Gene Therapy - Introgen: Advexin molecular targeted therapy is active in multiple cancers

Cancer Gene Therapy - Medulloblastoma gene therapy delivered by human neural stem cells

Cancer Gene Therapy - Myeloid progeny cell cytoskeleton reconstituted by retroviral-aided gene transfer

Cancer Gene Therapy - Scientists at Epeius Biotechnologies Corporation discuss research in cancer gene therapy

Cancer Immunotherapy - Human tenascin-C domain C is a target of monoclonal antibodies

Cancer Immunotherapy - Lentigen gets SBIR to evaluate lentiviral-engineered T cells for cancer immunotherapy

Cancer Prevention - Cancer preventive ellagic acid accumulates in digestive tract epithelial cells

Cancer Research - Yale, National Foundation for Cancer Research establish center for cancer drug design and discovery

Cancer Therapy - Biological functions of a possible tumor suppressor characterized

Cancer Therapy - BiovaxID formulation improves survival in cancer that has relapsed after chemotherapy

Cancer Therapy - Bispecific antibody targeting tumor vessels improves efficacy of radiotherapy

Cancer Therapy - Cytopia files for Phase l oral trial of CYT997 vascular targeting agent against cancer

Cancer Therapy - Effect of protein loss on spontaneous gynecological tumor development clarified

Cancer Therapy - European Medicines Agency supports docetaxel in combination therapy for head and neck cancer

Cancer Therapy - Glioblastoma chemotherapy-radiotherapy regiment evaluated

Cancer Therapy - High bread consumption is associated with increased risk of renal cell carcinoma

Cancer Therapy - Liver cancer cell interferon-mediated inhibition varies in different cell lines

Cancer Therapy - New genomic tests guide choice of chemotherapy in cancer patients

Cancer Therapy - Pioneering study looks at p53's role in tumor-stroma interactions

Cancer Therapy - Prima Biomed, Burnet Institute close strategic agreement for cell therapies for cancer

Cancer Therapy - Rexahn announces conclusion of Phase I cancer clinical trial of RX-0201

Cancer Therapy - Study anticipates rapid growth in kinase drug development space

Cancer Vaccine - Abagovomab shows promise for epithelial ovarian, fallopian tube, or primary peritoneal cancer

Cancer Vaccine - Immune resistance orchestrated by tumor microenvironment is focus of review

Cancer Vaccine - Tumor-associated antigen-specific DNA vaccine induces protective and therapeutic antitumor immunity

Cancer Vaccines - Research on cancer vaccines discussed by scientists at Center of Molecular Immunology

Carcinogenesis - Investigators at Oregon State University release new data on carcinogenesis

Carcinoid Cancer - Callisto opens first site for phase II trial of Atiprimod in advanced carcinoid cancer

Carcinoid Tumors - Carcinoid tumors could potentially be treated by targeted inhibition of protein kinase D family

Cardiology - Antithrombotics are underused in high-risk elderly atrial fibrillation patients

Cardiology - Apical ballooning syndrome-associated myocardial perfusion abnormalities are studied

Cardiology - ASO device closure is guided by RT 3-D transthoracic echocardiography

Cardiology - Asymptomatic AF and stroke evaluation in pacemaker patients is studied

Cardiology - Atrial fibrillation management is reviewed

Cardiology - Atrial fibrillation treated with rate control is studied in RACE II

Cardiology - Blind subxiphoid pericardiotomy for cardiac tamponade due to acute hemopericardium is safe, quick

Cardiology - Cardiogenic shock patients are treated with the TandemHeart pVAD

Cardiology - Catheter ablation for AF guided by CT integration shows reduced fluoroscopy time, arrhythmia recurrence

Cardiology - Dronedarone is an emerging agent with rhythm- and rate-controlling effects

Cardiology - Extrathoracic MRI safety in nonpacemaker-dependent patients is investigated

Cardiology - Hemodynamic energy from a combined centrifugal pump and IABP is assessed

Cardiology - Infective endocarditis characterized in a Finnish teaching hospital over 25 years

Cardiology - Interactions between paced wavefronts and monomorphic ventricular tachycardia described

Cardiology - Marshall vein examined as arrhythmogenic source in patients with atrial fibrillation

Cardiology - Medical management of atrial fibrillation considered in a review

Cardiology - MRI is performed in patients with selected implantable cardiac devices

Cardiology - Myocardial damage marker release is compared between on-pump and off-pump bypass surgery

Cardiology - Neointimal growth after vascular injury requires protein kinase C

Cardiology - Neurally mediated syncope is not predicted from tilt testing or ATP test

Cardiology - PDL BioPharma announces physician survey results on heart attack treatment

Cardiology - Pediatric mechanical circulatory support devices and their use are reviewed

Cardiology - Pediatric percutaneous VADs are placed using trans-hepatic cannulation

Cardiology - Pediatric ventricular assist device development program is reviewed

Cardiology - Pericardial effusion a late sign of ovarian hyperstimulation syndrome

Cardiology - Pulsatile pump system is used as an ECMO or a VAD support in pediatric patients

Cardiology - Rhythm and rate control in atrial fibrillation patients are focus of review

Cardiology - Safety and efficacy of circumferential ablation with pulmonary vein isolation for AF described

Cardiology - Tachyarrhythmias were characterized in ischemic vs. nonischemic patients with biventricular ICDs

Cardiology - Ventricular septal rupture is repaired using an infarct-exclusion technique

Cardiomyocytes - Cardiomyocytes under oxidative stress are not protected by 2,3-butanedione monoxime

Cardiovascular Disease - Acute coronary syndrome is associated with expression of platelet collagen receptor glycoprotein VI

Cardiovascular Disease - Change in cardiovascular risk between renal transplant patients is monitored in FAVORIT trial

Cardiovascular Disease - Coronary risk factors persist 12 to 18 months after percutaneous coronary intervention

Cardiovascular Disease - Dyslipidemia treatment recommendations of Canadian Cardiovascular Society have been updated

Cardiovascular Disease - Left and right ventricular function is impaired in Behcet disease

Cardiovascular Disease - Myofibrillar remodeling in cardiac-hypertrophy, heart failure and cardiomyopathies is reviewed

Cardiovascular Disease - Patterns in congenital heart disease suggest prophylaxis against dental, cutaneous sources

Cardiovascular Disease - Post-myocardial infarction adherence to beta-blocker therapy is poor during the first year

Cardiovascular Disease - Restenosis and coronary artery disease extent after PCI were evaluated by dobutamine stress MCPI

Cardiovascular Disease - Vascular ectasia of the upper GI is treated with endoscopic laser therapy

Cardiovascular Research - Condition could predict life or death in heart patients

Cardiovascular Research - Contractility after cardioversion of atrial fibrillation was fully restored in goat by AVE0118

Cardiovascular Research - FAK-related nonkinase attenuates cardiomyocyte hypertrophy induced by angiotensin-II

Cardiovascular Research - LVAD prolonged support-associated changes in collagen composition are studied

Cardiovascular Research - Off-pump bypass surgery may reduce strokes and other complications

Cardiovascular Research - Particle deposition in hypertensive rats establishes relation between measured and estimated dose

Cardiovascular Research - Researchers zero in on how the body regulates its response to heat stress

Cardiovascular Research - Right ventricular afterload quantified in patients with and without pulmonary hypertension

Cardiovascular Research - Tachycardia enhances cardiac oxidative stress, activates kinases responsible for cardiac remodeling

Cataracts - Cholecystokinin octapeptide-8 may be a useful therapeutic agent against diabetic cataract

Cataracts - Positive clinical data released on Visiogen lens for presbyopia correction after cataract surgery

Cell Biology - Endothelial cell tissue transglutaminase may modulate angiogenesis cytokine

Cell Biology - Receptor-based mobilization of internal calcium assayed

Cell Physiology - Cell polarity and focal adhesion turnover regulated in migrating cells

Cell Physiology - Nucleoporin is required for nuclear protein export

Child Abuse - Childhood abuse can impact the victims' adult relationships

Cholangiocarcinoma - Cholangiocarcinoma prognosis parallels Akt expression

Chronic Ischemia - Arteriocyte completes phase I stem cell clinical trial enrollment

Chronic Kidney Disease - Amgen receives complete response letter for extended dosing of Aranesp

Chronic Liver Disease - Fatty liver disease and liver cirrhosis role of adiponectin clarified

Chronic Myelocytic Leukemia - Antisense drug targeting c-myb oncogene starts phase I trial in cancer

Chronic Myelogenous Leukemia - Pediatric chronic myelogenous leukemia patients responded to interferon-alpha 2b and cytarabine

Chronic Obstructive Pulmonary Disease - Prevalence of chronic obstructive lung disease in Sweden is reported

Chronic Obstructive Pulmonary Disease - Spirometers technical properties and user friendliness are compared

Clinical Trials - beta2-integrin MAC-1 expression in human T-lymphocytes is inhibited by telmisartan

Clinical Trials - Coronary arterial remodeling assessments by static and serial measures are discordant

Clinical Trials - CVD risk factors in elderly improved with multifactorial intervention but without clinical benefits

Clinical Trials - Interventional vs. conservative treatment in acute non-ST elevation coronary syndrome examined

Clinical Trials - Mortality, congestive heart failure are reduced in MI patients with early zofenopril administration

Clinical Trials - OMRIX Biopharmaceuticals announces positive Phase III clinical trial results for human thrombin

Clinical Trials - Ostial vs. extra-ostial PV ablation strategies compared for atrial fibrillation treatment

Clinical Trials - Preterm ventilated infants were assessed for persistent pain, distress, adequacy of analgesia

Clinical Trials - Researchers examine whether patients undergoing surgery should be given blood thinners

Clinical Trials - Rhythm control for persistent atrial fibrillation is not improved with acute serial cardioversion

Clinical Trials - Topical anesthesia with EMLA reduces pain during endomyocardial biopsy

Clinical Trials - VALIANT trial shows marked geographic variation in acute myocardial infarction treatment

Clostridium Difficile-Associated Disease - ViroPharma launches initiatives to combat bacterial diseases

Cognitive Science - Blood pressure reduction appears to have heterogeneous effect on cognitive function

Cognitive Science - Donepezil improves cognition of patients undergoing electroconvulsive therapy

Collaborations - Accium BioSciences, CMIC partner to provide services to Japanese pharmaceutical firms

Collaborations - Arbor Vita and NoNO ink deal for stroke treatment

Collaborations - Bayer HealthCare, Regeneron to collaborate on VEGF Trap to treat eye diseases

Collaborations - BioGaia signs agreement with Ewopharma

Collaborations - Cambridge, MSM Protein partner in the field of multi-spanning membrane proteins

Collaborations - Kohden America, Masimo sign patient monitoring agreement

Collaborations - Medicexchange forms collaboration agreements with two digital medical imaging companies

Collaborations - Stereotaxis, Baylis collaborate to develop magnetically steered radio frequency guidewires

Collaborations - U.S. Genomics, Lahey Clinic alliance to study role of microRNAs in prognosis of urologic cancers

Collaborations - Verathon partners with Parker Medical to provide GlideRite endotracheal tubes

Colon Cancer - Genetic variation impacts aspirin's effectiveness in preventing colon cancer

Colon Cancer - Increased colorectal screening has reduced the incidence of colorectal cancer

Colon Cancer - Studies from Teikyo University, Department of Surgery in the area of colon cancer described

Colorectal Cancer - Colorectal and gastric carcinomas linked to occasionally mutated CASP6 gene

Colorectal Cancer - Colorectal cancer and poor survival follow lactate dehydrogenase 5 activation of angiogenesis

Colorectal Cancer - Colorectal cancer demographics and tumor characteristics in the United States described

Colorectal Cancer - Colorectal carcinoma survivors are at excess risk for developing subsequent primary cancers

Colorectal Cancer - Elderly colorectal cancer patients treated by bowel resection

Colorectal Cancer - Elderly colorectal cancer patients treated with oxaliplatin plus fluorouracil/leucovorin

Complementary & Alternative Medicine - Asterosaponin 1, isolated from starfish Culcita novaeguineae, induces apoptosis in glioblastoma

Complementary & Alternative Medicine - Complementary and alternative medicine use by cancer patients and survivors studied

Complementary & Alternative Medicine - Major components of Si-Ni-San that prevent contact sensitivity are identified

Congestive Heart Failure - Contemporary performance of surgical ventricular restoration procedures are reviewed

Coronary Angiography - Mitral annular calcification detected by echocardiography independently predicts mortality

Coronary Artery Bypass - Racial disparities in coronary artery bypass outcomes are examined in review

Coronary Vascular Disease - Avi BioPharma initiates Neugene antisense program in coronary artery bypass grafting

Corynebacterium Pseudotuberculosis Vaccine - Vaccination significantly protects against Corynebacterium pseudotuberculosis

Critical Care Medicine - Cardiac resynchronization device diagnostics and clinical application are reviewed

Critical Care Medicine - ECMO in a pediatric population has excellent outcome with anticoagulation strategy

Critical Care Medicine - Endobronchial intubation risk due to short trachea predictive factors are determined

Critical Care Medicine - Fluid resuscitation after hemorrhagic shock is better using gelatin or blood

Critical Care Medicine - Response to recombinant factor VIIa predicted patients with severe hemorrhage

Critical Care Medicine - Sepsis patient postoperative survival outcome predictors are assessed

Critical Care Medicine - Trauma effects on skin perfusion are evaluated using video angiography

Crohn Disease - Crohn disease and spondyloarthropathy chronic inflammation clustered genes are identified

Crohn Disease - Crohn disease prevalence of three gene mutations established

Cryopreservation - BioLife, Corning announce increased cell performance through product combination

Cryopreservation - Fresh versus cryopreserved stem cells compared for allogeneic transplantation

Cryptosporidiosis Epidemiology - Information sources influence perceived causes of sporadic cryptosporidiosis

Cystic Fibrosis - Newborn screening for cystic fibrosis may improve child survival

Cystic Fibrosis - Tobramycin once-daily are compared to thrice-daily treatments

Dendritic Cell Vaccine - Plasmacytoid dendritic cells induce distinct cytokine pattern in CD4+ T cells modulated by CpG ODN

Dengue Vaccine - Antibody responses to combinations of dengue virus vaccines are described

Dengue Vaccine - Dengue DNA vaccine elicits neutralizing antibody to four virus serotypes

Dental Research - American Dental Association applauds health claim for fluoridated bottled water

Dental Research - Delta Dental Plans reports many common foods contain more sugar than candy

Dental Research - Dental porcelain surface roughness effects of finishing techniques are assessed

Dental Research - Implant-supported mandibular overdentures can be immediately loaded

Dental Research - Oragenics reports positive clinical results with oral probiotic mouthrinse

Dental Research - Osseointegrated dental implant risk of failure is correlated with smoking

Dental Research - Psychogenic prosthesis incompatibility is diagnosed using psychologic tests

Depression & Diabetes - Diabetics with PTSD and depression may have higher substance use and weight problem risks

Depression Therapy - Escitalopram was better than citalopram for treatment of depression

Depression Therapy - No sustained effect of bright light after discontinuation was found for depression

Dermatology - Academy recommends encouraging a lifetime of healthy skin right from the beginning

Dermatology - Facial brighteners may be replacing wrinkle creams

Dermatology - Killed Mycobacterium vaccae suspension does not ameliorate atopic dermatitis in children

Dermatology - Nail care myths and facts discussed

Dermatology - Psoriasis' skin symptoms may be just the tip of the iceberg

Dermatology - Women's skin tone influences perception of beauty, health and age

Developmental Biology - Gene regulatory networks in cardiac evolution and development are discussed

Diabetes & Heart Disease - Diabetes and cardiovascular risks may increase due to GnRH agonist therapy for prostate cancer

Diabetes & Heart Disease - Metabolic therapy for diabetes mellitus and coronary artery disease patients is presented

Diabetes Complications - Body fat percentage and plasma glucose predict sialic acid levels in type 2 diabetes mellitus

Diabetes Complications - Bone formation around immediately placed oral implants is impaired in diabetic rats

Diabetes Complications - Cytokines protect against diabetes-related myocardial ischemia-reperfusion injury

Diabetes Complications - Diabetes does not adversely impact rehabilitation of elderly hip fracture patients

Diabetes Complications - Diabetes requiring insulin or antidiabetic therapy is linked to high death and complication risk

Diabetes Complications - Diabetes was independent determinant of allograft reinnervation in cardiac transplant patients

Diabetes Complications - Diabetics with no obstructive CAD evidence have impaired myocardial blood flow reserve

Diabetes Complications - Education helps to reduce problems related to travel in diabetes mellitus

Diabetes Complications - Glutathione and antioxidant enzymes in saliva are related to oxidative stress in diabetics

Diabetes Complications - In diabetes mellitus, cGMP signaling pathway activation is essential in delaying oocyte aging

Diabetes Complications - In type 1 diabetes, age, diabetes duration, hypertension and HDL affect carotid artery IMT

Diabetes Complications - New-onset diabetes increases the risk of all-cause and cardiovascular mortality

Diabetes Complications - Paraoxonase I genotypes were linked to high urinary albumin loss and diabetes complications

Diabetes Control - Behavioral family systems therapy improved family relationships and control in youth with diabetes

Diabetes Control - Continuous glucose monitoring system was accurate during hyperglycemia and ketotic development

Diabetes Control - Diabetes management was assessed through the quality and outcomes framework

Diabetes Control - Diabetic beta cells are destroyed by cytotoxic T cells

Diabetes Control - Diabetic nephropathy genetically controlled in a mouse model

Diabetes Control - In type 2 diabetes, self-management profiles and metabolic outcomes are assessed

Diabetes Control - JEVIN trial provides summary of blood pressure and metabolic control in insulin-treated diabetics

Diabetes Control - Stanford studies online diabetes self-management program

Diabetes Epidemiology - Calpain-10 gene affects type 2 diabetes risk in Europeans

Diabetes Epidemiology - TCF7L2 is type 2 diabetes susceptibility gene with a large effect on individual risk

Diabetes Epidemiology - Transcription factor 7-like 2 (TCF7L2) gene polymorphisms are linked to type 2 diabetes in Amish

Diabetes Epidemiology - Type 1 diabetes is linked to HIF beta-homologous Arntl2 gene

Diabetes Pathogenesis - Aging correlates with lower beta-cell proliferative capacity and higher apoptosis sensitivity

Diabetes Pathogenesis - Glucose induces opposite [Ca2+]i oscillatory patterns within intact islets of langerhans

Diabetes Pathogenesis - In diabetes-induced oxidative stress, retina appears to be affected earlier than hippocampus

Diabetes Pathogenesis - In diabetic model, hyperphagia is linked to leptin resistance and NPY mRNA in arcuate nucleus

Diabetes Pathogenesis - Insulin-like growth factor receptor functions in kinase phosphorylation

Diabetes Pathogenesis - Lipid abnormalities are prevalent in youth with type 1 and type 2 diabetes

Diabetes Pathogenesis - Thymic proinsulin expression is probably Pdx-1 independent

Diabetes Pathogenesis - Transition to autoimmune diabetes can be inhibited by regulatory pathway control of Th1 cells

Diabetes Pathogenesis - Vasoconstrictor response to ET-1 in diabetic renal artery preparations is studied

Diabetes Research - 13C-octanoic acid breath test is useful for studying gastric emptying in diabetic patients

Diabetes Research - Diabetes gene carries a similar risk to obesity

Diabetes Therapy - In diabetic peripheral neuropathic pain patients, duloxetine was well tolerated

Diabetes Therapy - In diabetics, local protease inhibitor treatment has beneficial effect on wound healing

Diabetes Therapy - In diabetics, measuring pain threshold via electrical stimulation is noninvasive and repeatable

Diabetes Therapy - Islet transplant with Edmonton protocol restores insulin and glycemic stability diabetics

Diabetes Therapy - Rosiglitazone reduces microalbuminuria and blood pressure independently of glycemia in diabetics

Diabetes Therapy - Three diabetic vitreous hemorrhage treatment techniques are similarly effective

Diabetes Therapy - Troglitazone upregulates nitric oxide synthase expression in vascular endothelial cells

Diabetes Vaccine - DNA vaccine generates regulatory T cell protection in type 1 diabetes

Diabetic Nephropathy - Diabetic nephropathy in rats is ameliorated by curcumin, the active principle of turmeric

Diabetic Nephropathy - Link between diabetic nephropathy and intrarenal oxygen in diabetes are reviewed

Diabetic Neuropathy - Avanir publishes phase II diabetic neuropathic pain trial results

Diabetic Neuropathy - Daily care helps avoid diabetic foot amputations

Diabetic Neuropathy - In women with type 2 diabetes mellitus, an ACE variant was linked to peripheral neuropathy

Diagnostics - AdvanDx releases data on identification of C. albicans, C. glabrata

Diagnostics - Color Doppler could not reliably depict cancer recurrence in patients treated with hormone therapy

Diagnostics - ECG criteria for detecting LV hypertrophy improved with mass estimation by 3D echocardiography

Diagnostics - External RNA controls for assessment of microarray performance were evaluated

Diagnostics - Lysosomal storage disorders are screened using chitotriosidase analysis

Diagnostics - MicroArray Quality Control project shows reproducibility of gene expression measurements

Diagnostics - New assay screens for inhibitors of hypoxia-inducible factor 2 activity

Diagnostics - Performance of one- and two-color platforms within MicroArray Quality Control project are similar

Diagnostics - Rat toxicogenomic study reveals analytical consistency across microarray platforms

Diagnostics - Tumor growth imaging after electrochemotherapy with cisplatin discussed

Diet & Nutrition - A significant amount of binge eating occurs in restaurants

Diet & Nutrition - Benign prostatic hyperplasia risk reduced with intake of selected micronutrients

Diet & Nutrition - Cancer survival might depend on season of diagnosis and sunlight exposure

Diet & Nutrition - Check for the heart-check mark when shopping for whole grains

Diet & Nutrition - Diet blogs make waves for new weight loss methods

Diet & Nutrition - Eight strawberries a day help keep colds, flu away

Diet & Nutrition - Study shows consumers unlikely to follow their own good advice on healthy eating, exercise

Diphtheria Epidemiology - Diphtheria immunity level satisfactory in children and adults in Israel

Diphtheria Vaccine - Oral diphtheria vaccine not effective

DNA Research - Duplex formation improves radiolabeled antisense DNA delivery in cell cultures

DNA Research - Horizontally acquired DNA identified by interpolated variable order motifs

DNA Research - mtDNA D-loop variant worsens pancreatic cancer prognosis and may indicate diabetes risk

DNA Research - Noncoding Y RNAs are required for human chromosomal DNA replication

DNA Research - Structure of T4 pyrimidine dimer glycosylase defined

DNA Vaccines - Research on DNA vaccines described by scientists at West Virginia University, Department of Obstetrics and Gynecology

Drug Delivery - Arnica montana bioactive constituent permeation through human skin is assessed

Drug Delivery - Drug/lactose comicronization by jet milling improves aerosolization

Drug Delivery - Meloxicam microemulsion system for transdermal delivery is developed

Drug Delivery - Nimodipine-loaded liposomes produce higher and more stable concentrations

Drug Delivery - Self-microemulsifying drug delivery systems containing atorvastatin are tested

Drug Development - Angiogenesis may be controlled by targeting receptor domains

Drug Development - Avi presents successful data using Neugene antisense to alter drug metabolism in humans

Drug Development - Drug delivery company MediVas reports positive preclinical ferret data in bird flu therapy

Drug Development - Exelixis files IND application for XL281 anticancer compound

Drug Development - Lexicon Genetics begins IND-enabling studies for LX2931 for autoimmune disease

Drug Development - NextBio introduces knowledge-based discovery platform

Drug Development - Novel neo-tanshinlactone analogues evaluated as anti-breast cancer agents

Drug Development - Photoresponsive prodrug of paclitaxel developed

Drug Development - Praecis Pharmaceuticals presents preclinical data on PPI-2458 as therapy for rheumatoid arthritis

Drug Development - Randomized approaches might decrease high failure rate for oncological drugs in phase III trials

Drug Development - Sequential genome-wide association test for analyzing adverse drug events is developed

Drug Development - Winning U.S. FDA approval for combination drugs is tougher

Drug Discovery - Researchers from University of California, Department of Pediatrics discuss findings in drug discovery

Drug Safety - Newer COX-2 selective inhibitors do not increase risk of angioedema

Drug Safety - Reckitt Benckiser urges clarity on latest European Medicine Agency ruling

Drug Safety - Systech key component of AstraZeneca's global product security initiative

Eating Disorders - Dieting can lead to eating disorders

Ebola Virus - Luciferase-based budding assay for Ebola virus is developed

Eczema - Celebrity photographer Jeremy Kost creates Images of Isolation to empower eczema patients

Embryo Cryopreservation - Liquid nitrogen-free system preserves embryo and embryonic stem cell viability

Embryonal Cancer - Primary germ cell tumors and thymoma linked to expression of octamer binding transcription factor

Embryonic Stem Cell Research - Embryonic stem cells have a unique epigenetic signature

Emergency Medicine - Presentation ischemia-modified albumin not effective risk stratifier for chest pain in ED

Endocrinology - Neuroendocrine cell type-specific expression of the chromogranin B gene defined

Endocrinology - Protein isoform displays stage-specific expression in mouse spermatids

Environmental Health - Environmental Quality Board approves Pennsylvania-specific plan to control toxic mercury emissions

Environmental Health - Supraventricular arrhythmia risk is increased in elderly by elevated sulfate, ozone levels

Enzymology - Cancer cell death is a function of granzyme B-induced apoptosis and growth inactivation

Enzymology - Kinases offer differential regulation of metalloproteinase

Enzymology - Pro and active forms of human enzyme bear structural differences

Enzymology - Ubiquitin ligases are found in a novel complex that is recruited to targets

Eosinophilic Esophagitis - Emerging gastrointestinal disease discussed at first-ever international symposium

Epilepsy - Cambria Biosciences presents new screening model for epilepsy drug discovery

Epilepsy - Nonconvulsive status epilepticus monitoring by EEG may be warranted in pediatric patients

Epilepsy - Seizure anticipation in epilepsy was investigated

Erectile Dysfunction - Central obesity is an independent predictor of erectile dysfunction in older men

Escherichia Coli Outbreaks - Shiga toxin-producing Escherichia coli 0148 outbreak caused by contaminated mutton

Esophageal Cancer - Nurses helped optimize patients' management after esophageal cancer surgery

Esophageal Cancer - Risk of esophageal carcinoma patients developing postoperative pneumonia linked to preoperative chemoradiation

Esophageal Cancer - Thoracic esophageal carcinoma poor survival linked to tumor depth and venous invasion

Esophageal Squamous Cell Carcinoma - Esophageal squamous cell carcinoma progression correlated with DRD2/DARPP-32 expression

Eyelid Lesions - Eyelid lesion standard of care improved

Facilities - Ablynx expands and relocates to new facilities

Facilities - American Oriental Bioengineering moves corporate headquarters to Shenzhen

Facilities - AspenTech forms global process modeling center of excellence

Facilities - MDS Pharma Services opens its first U.S. central lab

Facilities - Repligen completes manufacturing facility expansion

Facilities - Texas Children's Hospital announces largest investment ever by single pediatric organization

Facilities - Tris Pharma unveils expansion of research facility

Fetal Cardiology - Prenatally diagnosed pulmonary atresia with ventricular septal defect characterized

Fibromyalgia Syndrome - Sosei starts phase 2 trial of non-opioid analgesic enantiomer in fibromyalgia syndrome

Finance - 3i backs Xthetix to bring therapeutic ultrasound product to consumer aesthetic market

Finance - Abbott reports strong third-quarter results, $2.5 billion share repurchase program

Finance - Abiomed reports expected 24% increase in revenue

Finance - Advanced Biotherapy completes stock sale and debt conversion

Finance - AEterna Zentaris closes secondary offering of shares of Atrium Biotechnologies

Finance - Amarin reports successful $18.7 million fundraising

Finance - American Stock Exchange lists common stock of Ivivi Technologies

Finance - Amylin Pharmaceuticals reports loss of $0.36 per share

Finance - Aspreva reports annual growth of CellCept prescriptions in the range of 20%-25%

Finance - Auriga Laboratories announces EquityNet Research initiates coverage

Finance - Baxter reports strong earnings for third quarter with EPS of $0.57 per share

Finance - Biomerica reports sales of $1.15 million

Finance - Boston Scientific reports 34% increase in sales

Finance - China Sky One Medical completes private equity financings of $3 million

Finance - Efficas raises $14.5 million in Series B funding

Finance - Georgia Tech, Emory, Medical College of Georgia partner on $10 million nanomedicine grant

Finance - Hoodia Products International reports Q3 net revenues up 126%

Finance - ICU Medical reports third quarter revenue of $48.6 million

Finance - Illumina reports third quarter total revenue of $53.5 million

Finance - Indevus announces receipt of $10 million milestone payment from Esprit Pharma

Finance - Innovative Biosensors expands A round financing to total of $6.25 million

Finance - Inovio Biomedical closes $15.25 million equity financing

Finance - Lifeblood Medical to receive U.S. Department of Defense funding for organ donation research

Finance - Lifecore Biomedical reports Q1 net sales of $15.0 million

Finance - Logical Images secures $2.7 million in funding from Ticonderoga Capital

Finance - MichBio announces Rapid BioSense wins $15,000 prize at MichBio Expo Launchpad Competition

Finance - National Institutes of Health grant to fund methamphetamine study

Finance - NMT Medical files shelf registration statement

Finance - PainCare Holdings unveils financial restructuring plan

Finance - Pharmacopeia to raise $25 million in underwritten offering of common stock

Finance - PPD reports third quarter 2006 financial results; net revenue up

Finance - Prana Biotechnology auditors provide going concern notice

Finance - Quest Diagnostics reports strong performance in third quarter 2006 on 16% revenue growth

Finance - SAP NetWeaver Fund makes strategic investment in ArisGlobal

Finance - Senesco Technologies announces completion of $2.3 million equity financing

Finance - Senesco Technologies reports fiscal 2006 $3,314,885 net loss compared to $2,978,918 in 2005

Finance - SonoSite reports Q3 2006 revenue up 16% over a year ago to $40 million in preliminary results

Finance - St. Jude Medical reports Q3 2006 net sales of $821 million up 11% compared to a year ago

Finance - Trimeris reports 29% increase in sales of Fuzeon

Finance - Trubion Pharmaceuticals announces initial public offering

Finance - U.S. Ex-Im Bank to support $9.38 million loan to Xechem Pharmaceuticals

Finance - University of New Mexico scientists get funding for non-invasive endometrial cancer test

Finance - Vasomedical records net loss of $0.01 per share

Finance - Vision-Ease Lens files registration statement for initial public offering

Finance - Wyeth reports 9% increase in revenue

Finance - Xencor completes $45 million financing with MedImmune Ventures, Novo Nordisk, HealthCare Ventures

Fitness & Wellness - Activity pyramid makes a point about childhood fitness

Fitness & Wellness - Caloric restriction and exercise were equally effective in reducing weight and adiposity

Fitness & Wellness - Explosive growth continues in express workouts

Fitness & Wellness - Fasting blood glucose is related to exercise capacity in coronary artery disease

Fitness & Wellness - Health and physical fitness are not adequately stimulated by equitation training in females

Fitness & Wellness - National Football League, American Heart Association bring exercise to the classroom

Fitness & Wellness - Resistance and cardiovascular training improve physical capacity in chemotherapy patients

Fitness & Wellness - Therapeutic corticosteroid does not appear to improve intense submaximal exercise performance

Flu Vaccines - Researchers from University of Bergen, Gade Institute report recent findings in flu vaccines

Follicular Lymphoma - Follicular lymphoma decreased survival linked to overexpression of SOCS3

Follicular Non-Hodgkin Lymphoma - Biovest's phase III therapy for follicular lymphoma gets support from phase II data

Food Safety - NSF study supports expanded use of Neogen's Soleris microbial test system

Food-Borne Illness - Diets with monensin or tylosin did not affect E. coli O157:H7 shedding by cattle

Fusion Proteins - Researchers from Korea Advanced Institute of Science and Technology publish findings in fusion proteins

Gallbladder Cancer - Gallbladder cancer patients might benefit from extrahepatic bile duct resection

Gallbladder Cancer - Gallbladder carcinoma apoptosis induced by arsenic trioxide

Gastric Cancer -  Helicobacter infection in gastric cancer patients stimulates angiogenesis protein

Gastric Cancer - Advanced gastric cancer tumors invite therapy, but response is variable

Gastric Cancer - Children with gastric cancer have different Helicobacter pylori genotypes than adults

Gastric Cancer - Data supports the use of BioCurex technology for gastric cancer

Gastric Cancer - Early gastric cancer prognosticated by nodal involvement

Gastric Cancer - Gastric adenocarcinoma poor prognosis linked to overexpression of phosphorylated histone H3

Gastric Cancer - Gastric cancer endoscopic mucosal resection methods reviewed

Gastric Cancer - Gastric cancer prognosticated by macroscopic tumor size

Gastric Cancer - Gastric cancer recurrence risk in transfused patients increased after splenectomy

Gastric Cancer - Gastric carcinoma characterized by Goseki classification

Gastric Cancer - Gastric precancerous lesion development linked to host-bacterial interactions

Gastric Cancer Genetics - Research from Institute of Chemistry and Genomic Research Center reveals new findings on gastric cancer genetics

Gastroenterology - Contribution of carboxylesterase isozymes to intestinal hydrolase activity clarified

Gastroenterology - Gastrointestinal stromal tumor outcome predicted by microsatellite DNA alterations

Gastroenterology - Principal metabolic regulators of KATP channel activity in beta-cells are MgATP and MgADP

Gastroenterology - Small bowel bacterial overgrowth is under-recognized malnutrition cause in older adults

Gastroenterology - Sterol transfer reconstituted by half-transporters

Gastroenterology - Study demonstrated AMITIZA showed efficacy as treatment for chronic constipation

Gastroenterology - The AGA Institute releases a report on the future of gastroenterology

Gene Chips - Researchers at Georg-August University, Department of Clinical Chemistry target gene chips

Gene Repair - Knowledge of mechanisms of action at molecular level lacking for targeted gene repair

Gene Research - 454 Sequencing reveals a new pathway in RNA interference

Gene Research - Genetic analysis separates Paget disease localization

Gene Research - HFI-1 gene has a key role in both oxygen sensing and heat shock pathway

Gene Research - Multiple human cancer outcome potentially predicted by chromosomal instability signature

Gene Research - Solexa announces sequencing of a human X-chromosome

Gene Research - University of Portsmouth develops DNA switch to interface living organisms with computers

Gene Therapy - Inovio gets $1.1M from U.S. DoD to apply gene delivery technology to biodefense-related vaccines

Gene Therapy - Researchers from Naval Health Research Center, Research Department publish new studies and findings in the area of gene therapy

Gene Therapy - Scientists at University of Innsbruck, Institute of Pharmacy publish research in gene therapy

Gene Therapy - Synthetic peptides maybe used to provide nonimmunogenic gene delivery

Gene Transfer - Simultaneous gene transfer of BMP-2 and BMP-7 induces rapid bone formation and BMP-4 expression

Genetics & Genomics - Alternative splicing regulator identified by an expression cloning strategy

Genetics & Genomics - Berkeley Cancer Genome Center to study tumor genomics

Genetics & Genomics - Expression profiling identifies pathways altered in cellular immortalization

Genetics & Genomics - Genome-wide linkage scans identify loci affecting total cholesterol, HDL-C, and triglycerides

Genetics & Genomics - Genomic identification of regions of unusual compositional properties reported

Genetics & Genomics - High interleukin-6 after arterial injury is related to insulin resistance and 174G->C variant

Genetics & Genomics - PerkinElmer introduces two comprehensive multiplexing platforms for genomic research

Genetics & Genomics - Reduced risk of coronary artery disease is associated with p22phox C242T gene polymorphism

Genetics & Genomics - Systolic BP in myocardial infarction survivors is linked to polymorphism of CYP4A11 gene

Geology - California's San Jacinto fault is younger that previously thought, but slip rate is faster

Geology - The Amazon River once flowed in the opposite direction

Geriatrics - Adhering to clinical guidelines decreases blood clots in the elderly

Geriatrics - Antihypertensive drug therapy and cognitive function correlations are found

Geriatrics - Depression, isolation, social support, and cardiovascular disease in older adults are examined

Geriatrics - Eating vegetables, not fruit, helps slow down the rate of cognitive change in older adults

Geriatrics - In older men, coping influences physical and metabolic health likely through emotional control

Geriatrics - Low testosterone levels may be associated with a higher risk of falling in older men

Geriatrics - Nutritional risk and low weight in community-living older adults were reviewed

Geriatrics - Recurrent hip dislocation is treated using minimally invasive acetabular augmentation

Glaucoma - Biovitrum initiates clinical phase II study of glaucoma treatment

Glial Tumors - Glial tumor aberrations detected by multiplex ligation-dependent probe amplification

Glioblastoma Multiforme - Glioblastoma multiforme invasion reduced by genistein and biochanin A

Glioma - Gliomas may resist apoptosis upon pBad upregulation

Glioma - Mechanism of glioma invasiveness studied

Global Warming - Soot from wood stoves in developing world impacts global warming more than expected

Graft-versus-Host Disease - Oral beclomethasone dipropionate effective for gastrointestinal acute graft-versus-host disease

Graft-versus-Host Disease - Osiris is granted European manufacturing certification for Prochymal

Graft-versus-Host Disease - Osiris Therapeutics receives approval to conduct Phase III clinical trial for lead stem cell drug

Hamartoma - Retinal astrocytic hamartoma diagnostic features described

Head & Neck Cancer - Head and neck cancer epidemiology investigated

Head & Neck Cancer - Laryngeal cancer linked to gastroesophageal reflux disease

Headache & Migraine - Botulinum toxin type A injections as treatment for migraine headache is reviewed

Headache & Migraine - TorreyPines initiates phase IIb trial in acute migraine for Tezampanel

Healthcare Access - People living in highly black concentrated neighborhoods more likely to report their health as poor

Healthcare Costs - Cost differences favor epoetin alpha over darbepoetin alpha in treating anemia in cancer patients

Heart Disease - APOE alleles are not associated with calcific aortic stenosis

Heart Disease - Asymmetric dimethylarginine is independent risk factor for coronary heart disease

Heart Failure - Cardiac sympathetic nerve activity in congestive heart failure is ameliorated with torasemide

Heart Failure - Contractile performance, HF propensity after MI are determined by cardiac S100A1 protein levels

Heart Failure - Excessive breathlessness in diastolic heart failure patients is characterized

Heart Failure - Late-stage heart failure shows increased renin-angiotensin system expression and mast cell density

Heart Failure - Neurohormonal markers in heart failure diagnosis and prognosis are focus of review

Heart Failure - Outcomes in peripartum cardiomyopathy improved with contemporary heart failure treatment

Heart Failure - Study attempts to predict which heart failure patients may die without treatment.

Heart Transplantation - Cardiac allograft vasculopathy is identifiable by donor age, wall motion score, AT-III staining

Heart Transplantation - Experimental cardiac transplantation of young hearts yields better graft performance

Heart Transplantation - Hypercholesterolemia and diabetes post-transplant risks are linked to NF-MACE

Heart Transplantation - Prostaglandin E1 testing in heart failure-associated pulmonary hypertension enables transplantation

Heart Transplantation - Survival after heart transplantation improved by HLA-DR matching

Helicobacter Pylori - Helicobacter protein expression correlates with gastric adenocarcinoma

Hematology - Anticoagulation is monitored during vascular surgery using the Hemochron

Hematology - Leukemia and lymphoma immunophenotypes are determined from an antibody microarray

Hematology - NovoSeven is first recombinant therapy for rare, life-threatening bleeding disorder

Hepatitis B Therapy - U.S. Food and Drug Administration approves new treatment for chronic Hepatitis B in adults

Hepatitis B Virus - Chronic hepatitis B characteristics clarified

Hepatitis B Virus - Chronic hepatitis B treatment with entecavir compared with lamivudine

Hepatitis B Virus - Hepatitis B antigens are targeted differentially by monoclonal antibodies

Hepatitis B Virus - Hepatitis B core recombinant antigen recovery improved by heat treatment

Hepatitis B Virus - Hepatitis B virus genotypes detected and quantified

Hepatitis B Virus - Hepatitis B virus replication is inhibited by emodin

Hepatitis B Virus - Hepatitis B virus variants associated with liver cirrhosis functionally analyzed

Hepatitis C Therapy - Roche advances oral polymerase inhibitor into Phase II study in patients with chronic hepatitis C

Hepatitis C Virus - Chronic hepatitis C efficacy of low-dose peginterferon with ribavirin clarified

Hepatitis C Virus - Chronic hepatitis C interferon-gamma gene polymorphism characterized

Hepatitis C Virus - Chronic hepatitis C intrahepatic T cells functionally evaluated

Hepatitis C Virus - Chronic hepatitis C long-term outcome clarified

Hepatitis C Virus - Chronic hepatitis C pathogenesis in children involves innate immunity

Hepatitis C Virus - Hepatitis C genotypes display differing response kinetics during treatment

Hepatitis C Virus - Hepatitis C liver cirrhosis related hypertension treated with receptor antagonist

Hepatitis C Virus - Hepatitis C virus core protein cleavage is dispensable for virus budding

Hepatitis C Virus - Hepatitis C virus envelope glycoprotein interactions enhance cellular binding

Hepatitis C Virus - Hepatitis C virus polymerase inhibitors studied during polymerization reaction

Hepatitis C Virus - Hepatitis C virus replication targeting achieved with a single lentiviral vector

Hepatitis D Virus - Hepatitis D virus ribozyme activity in monovalent cations clarified

Hepatitis Vaccine - Hepadnavirus vaccine development aided by delipidation

Hepatocellular Cancer - Hepatocellular cancer prognosis after resection predicted by preoperative FDG-PET

Hepatocellular Cancer - Hepatocellular carcinoma prognosticated by expression of RhoA GTPases

Hepatocellular Cancer - Increased hepatocellular carcinoma risk linked to liver intestine-cadherin haplotype

Hepatoma - Morris hepatoma cell apoptosis genes are induced by angiopoietin overexpression

Hepatoma - Morris hepatoma growth and vascularization inhibited by troponin overexpression

Herpes Simplex Virus Transmission - Herpes simplex virus type 1 and HSV-2 commonly transmitted among HIV negative gay men

HIV/AIDS & Lung Cancer - HIV-infected lung cancer patients have shortened survival due to delayed diagnosis

HIV/AIDS Behavioral Medicine - Alcohol use increases HIV transmission risk among sexually transmitted infection clinic patients

HIV/AIDS Behavioral Medicine - Drug users receiving detoxification treatment do not change risky drug use and sexual behavior

HIV/AIDS Behavioral Medicine - Risk factors identified for HIV infection among female sex workers in Guyana

HIV/AIDS Behavioral Medicine - Women married to injecting drug users do not initiate condom use for fear of partner reaction

HIV/AIDS Cancer - HIV-related neoplastic complications and endemic virus-associated tumors increasing in Africa

HIV/AIDS Diagnostics - Competitive peptide enzyme immunoassay sensitive for HIV-1 subtype C infection

HIV/AIDS Diagnostics - Quasi-lentiviral protein reporter has nuclear export features of late HIV-1 transcripts

HIV/AIDS Diagnostics - Simple assay monitors CD4+ cells in HIV/AIDS patients in resource-limited settings

HIV/AIDS Diagnostics - U.S. FDA grants approval for MedMira's third-generation rapid HIV test

HIV/AIDS Drug Adherence - HAART adherence assessed by pharmacy claims predicts survival in HIV/AIDS patients

HIV/AIDS Drug Development - N-acetylcysteine amide prevents HIV-1 gp120- and Tat-induced oxidative stress in brain cells

HIV/AIDS Drug Development - Triterpene derivatives are potent anti-HIV agents

HIV/AIDS Epidemiology - HIV infections identified among spouses of HIV-infected persons on HAART

HIV/AIDS HAART - HIV-1 integrase inhibitor GS-9137 well-tolerated and effective in HIV/AIDS patients

HIV/AIDS HAART - Increased body mass index does not alter response to initial HAART

HIV/AIDS HAART - Oral tenofovir lowers SIV infection rate at birth but is less effective at 4 weeks of age

HIV/AIDS Microbicide - HIV neutralization achievable with postcoital microbicide coating thicknesses

HIV/AIDS Pathogenesis - GALT is an important reservoir of potentially replicative cells containing HIV-1 DNA

HIV/AIDS Pathogenesis - HIV-specific cell activation trigger efficient viral spread in lymphocytes

HIV/AIDS Prevention - HIV-1 integrase activity inhibited by synthetic peptides

HIV/AIDS Prognostics - Longer time on HAART and higher CD4 cell counts at initiation related to death from non-AIDS causes

HIV/AIDS Sexual Health - HIV infection associated with subpreputial penile wetness in uncircumcised men

HIV/AIDS Stigma - Public stigma is the highest towards HIV/AIDS in Hong Kong

HIV/AIDS Testing - HIV protease inhibitors screened by cytotoxicity protection

HIV/AIDS Vaccine - Replication-competent R5 simian-HIV encoding HIV clade C env clone is mucosally transmissible

HIV/AIDS Vaccine - SIV multigene prime/protein boost vaccine regimen protects against rectal challenge

HIV/AIDS Vaccines - Research conducted at National Institutes of Health has updated our knowledge about HIV/AIDS vaccines

HIV/AIDS Vision - Microvascular blood flow in the posterior retina is reduced in HIV/AIDS

HIV/Tuberculosis Coinfection - HAART substantially reduces mortality rate in HIV/tuberculosis-coinfection

Hormone Therapy - Hormone therapy may resurface as treatment to adjust children's height to social norms

Human Papillomavirus Epidemiology - HPV infection is highly prevalent among sexually active men

Human Parvovirus - Pregnant women with low parvovirus B19 DNA and B19-specific IgG are not vertically infectious

Huntington Disease - Medivation begins phase 1-2a trial of neuroprotective Dimebon in Huntington disease

Hypertension - Blood pressure regulation may involve endogenous activator of Rho-kinase

Hypertension - CVRx receives approval for Rheos Baroreflex Hypertension Therapy System trial

Hypertension - Hypertensives may have higher heath risks and should have routine microalbuminuria monitoring

Hypertension - Impact of the time rate of blood pressure variation on left ventricular mass characterized

Hypertension - Low nephron number hypertension is linked to hepatic and renal IGF system dysregulation

Hypertension - Oxidative stress and inflammation in hypertension pathogenesis are focus of review

Hypertension - Reactive oxygen species and vascular remodeling in hypertension are focus of review

Hypertension - Study shows universality of blood pressure reduction with device-guided breathing

Hypoxia - Hypoxia-inducible protein regulates erythropoietin production

Imaging - Cardiac 11C-meta-hydroxyephedrine retention depends on norepinephrine transporter density

Imaging - DTI-based diffusivity measures may detect subtle microstructural brain changes

Imaging - Focal scarring in LV hypertrophy correlates with LV remodeling severity

Imaging - Imaging of caspase activation in apoptosis reported

Imaging - Intravascular ultrasound nonlinear beams are investigated using a simulation tool

Imaging - Molecular imaging of receptor kinase activity in tumors achieved

Imaging - Philips offers expanded ultrasound technologies

Immunology - Recent studies from University of Oxford, Weatherall Institute of Molecular Medicine add new data to immunology

Infectious Diseases - Fabry disease protects against enterohemorrhagic Escherichia coli

Infectious Diseases - Human brucellosis displays cytokine gene polymorphisms

Infectious Diseases - Infection-related intestinal epithelial tight junction integrity studied

Influenza - Los Alamos licenses avian flu modeling & simulation software to CIVA

Influenza - NanoViricides finds FluCide-I superior to oseltamivir in preliminary animal studies

Influenza Outbreaks - Off-season influenza outbreak in Nagasaki caused by amantadine-resistant H3N2 clade

Influenza Pandemic - Central planning needed for containment of pandemic influenza

Influenza Vaccine - Flu vaccine appears safe for young children

Influenza Vaccine - Immunogenicity of influenza A/Duck/Singapore/3/97(H5) vaccines in ferrets was examined

Influenza Vaccine - Influenza vaccination safe and well tolerated in breast cancer patients

Influenza Vaccine - Intranasal flu vaccine produces higher antibody responses in young children than injectable

Influenza Vaccine - Vical's Vaxfectin adjuvant boosts immune response to seasonal flu vaccine

Information Technology - eICU program saves lives and improves patient outcomes, says VISICU

Information Technology - NetRegulus announces Nonconformance quality application for life sciences companies

Information Technology - Phase Forward's InForm EDC solution implemented for large-scale tuberculosis study in South Africa

Information Technology - Recent study points to cost savings with ORBIS hospital information system

Information Technology - Rockwood Clinic selects ProVation MD software for gastroenterology procedure documentation, coding

Insect Research - Honey bee genome holds clues to social behavior

Insulin - Glucose metabolism and the NAD biosynthesis may be linked by visfatin

Insulin - Specific protein kinase C isoforms may be transducers and modulators of insulin signaling

Insulin Resistance - Lower PPARGC1 expression seen in prediabetics may result from lipid-induced insulin resistance

Intracranial Oligodendroglioma - Intracranial oligodendroglioma survival predicted by recently proposed scoring scale

Intracranial Tumors - Children with intracranial tumors and extraneural metastasis linked to poor outcomes

Irritable Bowel Syndrome - Targeted antibiotics lead to prolonged improvement in irritable bowel syndrome symptoms

Ischemia - Biventricular vs. right ventricular pacing may be preferable in ischemic cardiomyopathy patients

Ischemia - Cardioprotection initiated by reactive oxygen species is dependent on PKCepsilon activation

Ischemia - Induced expression of adenosine receptor subtypes may participate in ischemia-reperfusion response

Ischemia - Myocardial preconditioning in anesthetized rats is preserved by chronic trimetazidine treatment

Ischemia - Paradoxical coronary microcirculatory constriction during ischemia described

Ischemia - Remote ischemic preconditioning protects against cardiopulmonary bypass-induced tissue injury

Kaposi Sarcoma - Kaposi sarcoma angiogenesis is influenced by latency-associated nuclear antigen

Keratoconjunctivitis Outbreaks - Epidemic keratoconjunctivitis caused by intermediate adenovirus 22/H8

Kidney & Cardiovascular Disease - Early renal damage in sustained primary hypertension is linked to increased arterial stiffness

Kidney & Cardiovascular Disease - Long-term dialysis patients less likely to undergo invasive cardiac procedures after acute MI

Kidney & Cardiovascular Disease - LV dysfunction and LV hypertrophy in end-stage renal disease linked to low triiodothyronine

Kidney & Cardiovascular Disease - NT-proBNP in chronic heart failure patients gives independent prognostic information

Kidney Disease - Oncocytomas diagnosed by percutaneous renal biopsy clinical outcomes are studied

Large Cell Lung Cancer - Large cell lung carcinoma pathogenesis linked to LKB1 mutation

Leiomyosarcoma - Leiomyosarcoma treated by prosthetic replacement of infrahepatic inferior vena cava

Leishmaniasis Therapy - Miltefosine analog with leishmanicidal activity is synthesized

Leukemia - Acute lymphoblastic leukemia cells respond to thalidomide analogue CC-4047

Leukemia - Acute myeloid leukemia survival predicted by functional status

Leukemia - Adult T cell leukemia/lymphoma progression linked to down-regulation of ASY/Nogo transcription

Leukemia - Leukemia bears N-terminally truncated protein with oncogenic properties

Licensing Agreements - Clinical Data signs exclusive license for monoclonal antibody pharmacogenetic patent portfolio

Licensing Agreements - Debiopharm and Cambridge Antibody Technology to develop and market gastric carcinoma therapy

Licensing Agreements - Osmetech licenses pharmacogenetic biomarker for P450-CYP2D6 from Epidauros

Licensing Agreements - PharmaNova grants exclusive U.S. license to Depomed for extended release gabapentin in hot flashes

Lipid Research - Scientist reports findings on discovery of cholesterol lowering component in soy

Lipolysis - PPAR gamma agonism increases adipose tissue lipolysis and glyceride lipases expression

Lipoproteins - HDL-C and body weight increased and remained elevated during long-term rosiglitazone use

Liposarcoma - Liposarcoma patient counseling aided by disease-specific survival nomogram

Liver Cancer Therapy - Jennerex and Green Cross agree to develop and commercialize JX-594 in South Korea

Lung Cancer - Annual low-dose CT screening detects lung cancer at earliest stage

Lung Cancer - Lung cancer disparities in African Americans discussed

Lung Cancer - Lung cancer patients responded well to gemcitabine and vindesine

Lung Cancer - Lung cancer patients survive longer when key genes are expressed

Lung Cancer - Lung cancer survival improved with smoking cessation

Lung Cancer - Lung cancer trials show therapeutic response outweighs disease stabilization

Lung Cancer - Lung cancers in non-smokers signal the presence of somatic mutations

Lung Cancer - Lung deformation estimated with four-dimensional computed tomography

Lung Cancer - Non-small cell lung cancer treated using cytotoxic agents

Lung Cancer - Non-small-cell lung cancer treated by oxaliplatin and docetaxel

Lung Cancer - Primary non-small-cell lung cancer staging practices reviewed

Lung Cancer - The fibrotic effects of bleomycin are not averted by fish oil

Lung Cancer Vaccine - Immune-modulating vaccines in non-small cell lung cancer are reviewed

Lung Transplantation - Respiratory viral infections can cause enhanced tracheal allograft rejection

Lymphoblastic Leukemia Therapy - Approval summary of nelarabine for T cell lymphoblastic leukemia and lymphoma is released

Lymphoma - Malignant lymphoma management costs in Germany might rise due to high prevalence among elderly

Lymphoma - Mantle cell lymphoma pathogenesis and survival linked to constitutive activation of PI3K/Akt

Lymphoma Therapy - Research data from Roche, Division of Hematology update understanding of lymphoma therapy

Malaria -  Plasmodium falciparum soluble histo-aspartic protease partial characterized

Malaria - Medicines for Malaria Venture, Genzyme, Broad Institute expand malaria drug discovery pact

Malaria - Positive second year results reported in Bioko Island malaria project in Equatorial Guinea

Marburg Virus Vaccine - Live vaccine provides cross-protection against Marburg virus strains

Marine Biology - Grey whales are bypassing traditional feeding grounds

Market Analysis - Discover applications of microarrays in pharmaceutical arena with new report

Market Analysis - Drug brands spend $15 million on first-year marketing according to new report

Market Analysis - Drug market shifts focus from 'blockbusters' to 'nichebusters'

Market Analysis - Expert Opinion releases series of reports on discontinued drugs in 2005

Market Analysis - Implementation biggest challenge to pharma market segmentation success, says Cutting Edge

Market Analysis - Increased use of Mylotarg and new drugs more than doubles the market for AML therapies

Market Analysis - Market opportunities great for life science suppliers in U.S. market for biodefense research

Market Analysis - Monoclonal antibody makers targeting smaller companies to acquire new technology, report says

Market Analysis - Ophthalmic market is forecasted to show steady growth over the next 5 years

Market Analysis - Report addresses current obstacles facing drug development from phytocompounds

Market Analysis - Report examines molecules in physico-chemical environment

Market Analysis - Report urges integrating pharmacokinetic and pharmacodynamic concepts into biotech drug development

Market Analysis - Research and Markets issues report on nanobiotechnology

Market Analysis - Research and Markets issues report on population genetics

Market Analysis - Study shows continuous process improvement feasible for clinical trial operations

Market Analysis - U.S. market for psoriasis therapeutics to surpass $9 billion by 2016

Market Analysis - Unfavorable tier placement makes safer insomnia drug less accessible to patients

Marketing - Medicure launches U.S. sales organization to support marketing of Aggrastat

Marketing - Pharmaxis appoints Aridol distributor for Italy

Measles Epidemiology - Methods to elute serum from dried blood spot samples for measles serology were compared

Medical Devices - Bovie Medical reports U.S. FDA clearance to market new laparoscopic instruments

Medical Devices - Imaging experts perform cardiac MRI scans by remote control

Medical Devices - Kane Biotech announces positive results from central venous catheter study

Medical Devices - Medtronic to initiate large clinical study evaluating drug eluting stent safety

Medical Devices - Olympus combines confocal and TIRF illumination in single microscope system

Medical Devices - Olympus offers multiphoton laser scanning microscope system

Medical Devices - Patrick Serruys, Thoraxcenter, Rotterdam, joins Tryton Medical's first-in-man study

Medical Devices - PerkinElmer launches new innovations in bio-imaging

Medical Devices - RITA Medical Systems announces 510(k) clearance of HABIB 4X laparoscopic device

Medical Devices - Tissue perfusion adequacy model for the pCO2 gap is developed

Medical Devices - TyRx Pharma submits premarket application for Pivit CRM

Medical Devices - Ultrasound experts support decision to deny over-the-counter sale of handheld doppler fetoscopes

Medulloblastoma - Medulloblastoma treated by craniospinal radiation therapy followed by adjuvant chemotherapy

Melanoma - Lentigo maligna and melanoma treated by Mohs micrographic surgery

Melanoma - Melanoma risk linked to ADP-ribosylation factor-like tumor-suppressor gene 1 variant Cys148Arg

Menopause - Bionovo completes enrollment of MF101 phase II trial for menopausal symptoms

Menopause - BioSante presents positive Bio-E-Gel data at North American Menopause Society Meeting

Menopause - Breast density is reduced by long-term raloxifene therapy in postmenopausal women

Menopause - Depomed obtains exclusive sublicense for Gabapentin use in hot flashes

Mental Health - Anxiety disorders linked to physical conditions

Mental Health - Associations between cognition and costs among people with schizophrenia were examined

Mental Health - Depression can be a more serious matter for men than women

Mental Health - Depression symptoms are less likely in kids with accurate self-perceptions

Mental Health - Depression, fatigue, and life orientation relations in myocardial infarction patients were examined

Mental Health - Effect of self-esteem and self-acceptance on psychological health is examined

Mental Health - Long-term health complaints after the Amsterdam Air Disaster in police officers and firefighters examined

Mental Health - SRI medication is effective in treating compulsive hoarding patients

Mental Health - Vagus nerve stimulation for chronic treatment-resistant depression is assessed

Mental Health - Women feel less trusting at work than men do

Mergers & Acquisitions - 3M acquires developer of 3-D imaging technology for dentistry Brontes Technologies

Mergers & Acquisitions - AngioDynamics to acquire Oncobionic and its new cancer therapy

Mergers & Acquisitions - Boehringer Ingelheim Pharmaceuticals agrees to acquire Zantac

Mergers & Acquisitions - Constella Group to acquire Research Triangle Park contract research organization

Mergers & Acquisitions - Cord Blood America announces acquisition of CorCell private cord blood banking company

Mergers & Acquisitions - Endo Pharmaceuticals acquires RxKinetix

Mergers & Acquisitions - ICOS Corp. announces agreement to be acquired by Eli Lilly & Co.

Mergers & Acquisitions - Inovio acquires rights to DNA vaccine licenses and intellectual property from Valentis

Mergers & Acquisitions - Natus Medical to acquire Olympic Medical

Mergers & Acquisitions - Parexel to acquire California Clinical Trials Medical Group and Behavioral and Medical Research

Mergers & Acquisitions - Pharming acquires DNage BV

Mergers & Acquisitions - Valentis completes sale of assets to Inovio Biomedical

Mesothelioma - Malignant mesothelioma treated by divided dose of cisplatin combined with gemcitabine

Mesothelioma Vaccine - Mesothelioma is targeted with infectivity-enhanced survivin/conditionally replicative adenoviruses

Microbiology - VTT Biotechnology describes research in microbiology

Molecular Biology - Benzamides and benzamidines selectively inhibit tyrosine kinases

Molecular Biology - Lawrence Berkeley National Laboratory opens the National Center for X-ray Tomography

Monoclonal Antibodies - Findings from Duke University, Human Vaccine Institute advance knowledge in monoclonal antibodies

Monoclonal Antibodies - Research in the area of monoclonal antibodies reported from Mie University, Department of Molecular

Monoclonal Antibodies - Researchers from Shantou University, Medical College report on findings in monoclonal antibodies

Monoclonal Antibodies - Scientists at Northwestern University, Department of Medicine target monoclonal antibodies

Monoclonal Antibodies - Studies from Tuen Mun Hospital, Department of Medicine yield new data on monoclonal antibodies

Mosquito-Borne Disease - Japanese encephalitis virus was found in mosquitoes collected in Korea

Mosquito-Borne Disease - West Nile virus from mosquitoes in ground and canopy habitats in Connecticut were examined

Multiple Myeloma - First tandem autotransplant trial long-term outcomes are assessed

Mumps Vaccines - Research on mumps vaccines detailed by scientists at Baylor College of Medicine, College of Medicine

Muscular Dystrophy - Muscular dystrophy associated-protein emerin is phosphorylated on Ser 49 by protein kinase A

Mycobacterium Tuberculosis Epidemiology -  Mycobacterium tuberculosis clade members detected in fish

Mycobacterium Tuberculosis Pathogenesis - C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis

Myelodysplastic Syndrome - New agents for management of myelodysplastic syndromes are focus of review

Myelodysplastic Syndrome - Patients with myelodysplastic syndrome might respond to everolimus

Myocardial Infarction - Delays and mortality in ST-elevation myocardial infarction are reduced bypassing the emergency room

Nanotechnology - Nanoparticle system achieves RNA interference

Nanotechnology - New nanotechnology data have been reported by scientists at SAIC-Frederick, Inc.

Nanotechnology - New nanotechnology findings from Max Planck Institute for Polymer Research published

Nanotechnology - New nanotechnology research has been reported by scientists at University of Utah, Department of Radiology

Nanotechnology - Reports from Marquette University describe recent advances in nanotechnology

Nanotechnology - Researchers' work from University of Technology focuses on nanotechnology

Natural Products - DHH105 raises glucose disposal by enhancing translocation of glucose transporter 4

Natural Products - Malabsorption of carbohydrate but not of triacylglycerol is seen after intake of tea extracts

Natural Products - Myocardial necrosis model shows myocardial salvaging effects of Ocimum sanctum

Neisseria Meningitidis - Multiple Neisseria meningitidis strains with epidemic potential circulate in Burkina Faso

Neurogenesis - Skin-derived precursors retain latent neurogenic properties after residing in non-neural tissue

Neurology - Cholecystokinin receptor deletion was linked to body weight and hypothalamic NPY content

Neurology - Electronic neural implant may help establish new nerve connections for controlling movement

Neurology - Neuren's third lead drug candidate, NNZ-2591, proves effective at reducing memory loss

Neurology - Pulsed magnetic field regenerative effects on injured peripheral nerves are studied

Neurology - Research sheds light on how brain injury leads to seizures, memory problems

Neurology - Researchers add to the understanding of how brain cells communicate

Neurology - Researchers examine killing brain tumors from within

Neurology - Study identifies brain cells that influence whether birds of a feather flock together

Neuroscience - Alnylam reports progress in preclinical programs

Neuroscience - Cultured hippocampal neuron glycosylation is altered by ethanol

Neuroscience - Drosophila odorant response requires nervous system expression of beta integrin gene

Neuroscience - Epilepsy-linked receptor function is alleviated by phenobarbital

Neuroscience - Juvenile neuronal ceroid lipofuscinosis autoantibody response patterned

Neuroscience - Kallikrein participates dynamically in traumatic spinal cord injury

Neuroscience - Neural progenitor proliferation increased by protein overproduction

Neuroscience - Neural regeneration protein is a neuronal survival-promoting factor

Neuroscience - Neurotechnology industry organization to advance treatments for brain, nervous system illnesses

Neuroscience - Overstimulation of prion protein signaling pathways injures neuronal cells

Neuroscience - Schwann cells produce phenotype-specific regeneration

Neuroscience - Scientists may have unlocked why memory declines with age

Neuroscience - Selective action of ifenprodil at the N-methyl-D-aspartate receptor probed

Neuroscience - Tau protein sequential phosphorylation generates a filamentous epitope

Neuroscience - Training enables seniors to operate with visual processing speed, accuracy of someone younger

Non-Hodgkin Lymphoma - Allogeneic-bone marrow transplant increases survival with less relapse in non-Hodgkin lymphoma

Non-small Cell Lung Cancer - U.S. FDA approves new combination therapy for lung cancer

Nonalcoholic Fatty Liver Disease - Familial aggregation of insulin resistance supports nonalcoholic fatty liver disease genetic link

Obesity Complications - BMI has significant effects on all of the lung volumes

Obesity Complications - In obese, increased airway responsiveness may be due to decreased lung volume

Obesity Complications - Sphingolipids play role in prothrombotic and proinflammatory phenotype of obese adipose tissue

Obesity Epidemiology - Children of obese mothers may be more responsive to environmental cues to eat

Obesity Epidemiology - Loss of one copy of the POW gene predisposes to obesity in humans

Obesity Pathogenesis - Adiponectin acts at AP to provide link between energy homeostasis and cardiovascular function

Obesity Pathogenesis - In obesity model, high mean arterial pressure is due to reduced NO/L-arginine system influence

Obesity Pathogenesis - Obesity does not correlate with altered peripheral blood lymphocyte cytokine gene expression

Obesity Pathogenesis - Severe obesity hepcidin expression is independent from diabetes

Obesity Pathogenesis - Total and abdominal adiposity in healthy adolescents is linked to inflammatory proteins

Obesity Prevention - Americans may be heeding the healthy eating message

Obesity Research - A hormonal link to obesity may save lives

Obesity Research - EPIX Pharmaceuticals announces findings from obesity and cognitive impairment studies

Obesity Research - Manhattan Pharmaceuticals includes morbidly obese in oral oleoyl-estrone clinical program

Obesity Research - Orexigen reports positive phase II results for Excalia combination therapy to treat obesity

Obesity Research - Polycystic ovary syndrome is more common in overweight women than in lean women

Obesity Therapy - AEterna Zentaris presents data on ghrelin antagonists' capacity of inhibiting food intake

Obesity Therapy - In obese hypoventilation syndrome, BPV-S/T improved oxygenation, sleep quality, and HRQL

Obstetrics - New fertility guidelines limit number of embryos transferred during in-vitro procedures

Oligodendroglial Tumors - Oligodendroglial tumors responded to carboplatin and etoposide chemotherapy

Oncology - Interleukin 1 beta controls the Myc-dependent angiogenic switch in tumors

Oncology - Solid tumors respond to heparanase inhibitor PI-88

Ophthalmology - Bevacizumab demonstrates cell-specific cytotoxity in the eye

Ophthalmology - Eye researchers develop a new 3-D monitor vision test for children

Ophthalmology - Hydrophilic acrylic IOL surface deposits are not clinically relevant

Ophthalmology - Moraxella keratitis predisposing factors and clinical management is studied

Ophthalmology - Murine terminally differentiated retina displays novel protein interaction

Ophthalmology - Northwest Lions Eye Bank provides corneal transplant tissue using IntraLase laser technology

Ophthalmology - Othera initiates Phase II trial for OT-551 in preventing cataracts resulting from retinal surgery

Oral Cancers - Oral cancers impacted by patient's delay, but reasons behind delay remain unclear

Oropharyngeal Candidiasis - BioAlliance Pharma receives marketing authorization for its first product, Loramyc

Orthopedics - Acetabular deficiencies are reconstructed using the longitudinal oblong revision cup

Orthopedics - Hip acetabular cement mantle and component positioning are not consistently achieved

Orthopedics - Knee arthroplasty using a third-generation, posterior-stabilized prosthesis is assessed

Orthopedics - Total hip arthroplasty-associated femoral fracture risk factors are determined

Orthopedics - Total knee arthroplasty-associated deep venous thrombosis therapies are compared

Osteoarthritis - European agency agrees with naproxcinod safety database

Osteoarthritis - New knee implant offers long-awaited option for osteoarthritis sufferers

Osteoarthritis - Obesity is having a significant impact on osteoarthritis

Otorhinolaryngology - Middle ear titanium ceramic prosthesis implantation is investigated

Otorhinolaryngology - Ototoxicity screening using high-frequency DPOAEs is investigated

Otorhinolaryngology - Speech perception abilities of children using CIs or digital hearing aids are studied

Ovarian Cancer - Antisoma presents positive data from AS1404 phase II trial in ovarian cancer

Ovarian Cancer - Ovarian cancer outcomes predicted by ErbB-3 expression

Paget Disease - Paget disease diagnosis and management guidelines reviewed

Pain Management - Laser therapy is effective for relieving chronic neck pain

Pain Management - Molecule is discovered to be genetic key to pain sensitivity

Pain Management - NeurogesX Phase III study in post-herpetic neuralgia meets primary endpoint

Pain Management - Neuropathic pain alleviated by injection of antisense oligonucleotides

Pain Management - New autologous treatment for tennis elbow may replace surgery for chronic sufferers

Pain Management - Oxytrex mechanism of action further elucidated as alternative to opioids for chronic pain

Pain Management - Pulsed radiofrequency current clinical applications and outcomes are reviewed

Pain Management - Pulsed radiofrequency denervation is used to treat sacroiliac joint syndrome

Pain Management - Pulsed radiofrequency is used to treat lumbar medial branch pain

Pain Management - Reliability of pain interference measures in multiple sclerosis was examined

Pain Management - Trigeminal neuralgia temporary analgesia is produced with intranasal lidocaine spray

Pain Management - YM BioSciences announces results of AeroLEF phase IIb open-label study

Pancoast Tumors - Pancoast tumor treated by multimodality therapy

Pancreatic Cancer - European agency recommends orphan drug designation for MediGene's pancreatic cancer drug candidate

Pancreatic Cancer - Racial disparity in pancreatic cancer treatment warrants further investigation

Pancreatic Cancer Treatment - Early immunization promotes lifelong control of pancreatic tumor progression

Pancreatic Cancer Treatment - p53-derived peptide blocks pancreatic cancer cell growth

Pancreatic Endocrine Tumors - Pancreatic endocrine tumors diagnosed by endoscopic ultrasound-guided fine-needle aspiration

Patents - Astex patents granted covering the use of key human cytochrome P450 structures

Patents - Auriga files multipurpose drug delivery patent application

Patents - BioSyntech receives notice of allowance for key BST-CarGel patent

Patents - Dyadic granted patent for high-throughput screening of expressed DNA libraries in filamentous fungi

Patents - MultiCell Technologies granted European patent on treatments for autoimmune diseases

Patents - Sionex Corporation granted seven new patents

Patents - SRU Biosystems receives key industry patent for label-free detection technology

Patents - TargeGen receives USPTO notice of allowance for U.S. patent application for edema compounds

Patents - Taro receives notice of allowance for U.S. patent for treatment of essential tremor

Patents - Victhom files a provisional patent application for sleep apnea

Pediatric Cardiology - Children with bicuspid aortic valve are at risk of dilatation of ascending aorta

Pediatric Cardiology - Mortality in pediatric heart surgery as an outcome parameter considered in review

Pediatric Cardiology - Normothermic bypass in pediatric surgery an excellent alternative to hypothermia

Pediatric Cardiology - Successful Fontan circulation may be marked by high ANP levels early after surgery

Pediatric Cardiology - Temporary shunt using centrifugal pump is helpful during bidirectional cavopulmonary shunt

Pediatric Hepatology - Biliary atresia splenic malformation syndrome is distinct subgroup with embryological onset

Pediatric Obesity - Researchers forecast childhood obesity rates to double within 10 years

Pediatric Obstructive Sleep Apnea - Childhood obstructive sleep apnea is related to low socioeconomic status

Pediatrics - Georgia Tech and Children's Healthcare of Atlanta partner to create a new pediatric research center

Pediatrics - Many teens lose migraines as they reach adulthood

Pelvic Inflammatory Disease - Low prevalence of tubo-ovarian abscess was found in adolescents with pelvic inflammatory disease

Penile Cancer - Penile cancer managed according to European Association of Urology guidelines

Peripheral Arterial Disease - Quantitative sensory testing detects sensory abnormalities in peripheral arterial disease

Personnel - Aethlon Medical names Robert H. Keller to HIV/AIDS science advisory board

Personnel - Alnylam Pharmaceuticals CEO John Maraganore, PhD, named to MacroGenics board of directors

Personnel - Andover Medical names Marshall Sterman to its board of directors

Personnel - Avalon Pharmaceuticals appoints David Kabakoff to its board of directors

Personnel - BioTrove names Edward L. Erickson to board of directors

Personnel - Cambridge Heart announces management change

Personnel - CardioDynamics announces Jay A. Warren joins board of directors

Personnel - CardioVascular BioTherapeutics appoints Mike Norris VP of business development

Personnel - CardioVascular BioTherapeutics elects Dr. Thomas Stegmann co-president

Personnel - Charles Macfarlane joins board of PharmaVentures

Personnel - Claus Braestrup, CEO of Lundbeck, appointed to Santaris Pharma Board

Personnel - Critical Therapeutics announces changes to board of directors

Personnel - Dr. Louis J. Ignarro, Nobel Laureate, joins Metagenics scientific advisory board

Personnel - Dr. Robert Bergstrom appointed vice president, business development at Pharmatek

Personnel - Emageon elects Doug French to its board of directors

Personnel - Enzo Biochem appoints former Novartis Pharmaceutical executive president of Enzo Therapeutics

Personnel - Human Genome Sciences appoints Kevin Starr to its board of directors

Personnel - Indevus names Thomas Farb as president and COO

Personnel - InfaCare names Dr. Ronald Dundore VP of regulatory and quality affairs

Personnel - John McNeil named scientific director of PATH Malaria Vaccine Initiative

Personnel - MedVenture Associates announces addition of executive in residence Charlie T. Liamos

Personnel - Micromet names Christopher P. Schnittker as senior vice president, chief financial officer

Personnel - MOCON names Donald N. DeMorett to board of directors

Personnel - Nicholas DeRoma and Eddie Cheung join board of American Liver Foundation

Personnel - PaperFree Medical Solutions announces appointment of Craig Barrow as chief financial officer

Personnel - Parexel appoints Dr. Sarah Warner to medical imaging group

Personnel - Parexel names financial executive Christopher Lindop to board of directors

Personnel - Paul Strauss, MD joins Omeros as vice president, Clinical Development

Personnel - Pfizer names senior executive to head expanded worldwide licensing and business development

Personnel - Philips appoints Rusckowski as CEO of Medical Systems division

Personnel - PortBlue names Dr. Daniel Lucey senior advisor to CommandAware

Personnel - Prolacta Bioscience names Scott Elster as CEO

Personnel - Quantum Genomics names Jean-Pierre Riffaud head of Preclinical Development

Personnel - Questcor announces appointment of new executive officers

Personnel - Reliant Technologies names Eric B. Stang as chief executive officer

Personnel - Ronnda Bartel, PhD joins Aastrom Biosciences as vice president Research & Development

Personnel - Schering-Plough CEO Fred Hassan named president of pharmaceutical manufacturers federation

Personnel - WuXi PharmaTech appoints Ee Hoon See as VP of human resources

Personnel - Zogenix appoints J.D. Haldeman VP

Pharmacology - Dose escalation and pharmacokinetic study of enzastaurin conducted in advanced cancer patients

Pharmacology - Pharmacokinetics and pharmacodynamics of epoetin alfa did not correlate in children with cancer

Pharmacology - Tasidotin hydrochloride was evaluated in patients with advanced solid tumors

Philanthropy - Christian Blind Mission presents check to Archbishop Desmond Tutu to help fight TB meningitis

Pneumococcal Vaccine - Many at-risk older adults were not receiving pneumococcal vaccine in England

Poliomyelitis Genetics & Genomics - Unusual mutation was detected within VP1 region of poliovirus Sabin vaccine re-isolates

Poliomyelitis Vaccine - Live-attenuated type 3 poliovirus vaccine constructions are genetically stable

Polycystic Ovarian Syndrome - An increase in polycystic ovarian syndrome concerns San Francisco area experts

Prion Disease - Styrylbenzoazole derivatives are useful for treatment of transmissible spongiform encephalopathies

Prostate Cancer - Cyanidin modulates prostaglandin E-2 production and cyclooxygenase-2 expression in prostate cancer cells

Prostate Cancer - Hormone refractory prostate cancer management reviewed

Prostate Cancer - Predictors of prostate-specific antigen recurrence after radical prostatectomy detailed

Prostate Cancer - Prostate cancer detection maximized by peripheral biopsies in repeat 12-core biopsy protocols

Prostate Cancer - Prostate cancer invasion regulated by G(12) family proteins

Prostate Cancer - Prostate cancer predicted by circulating tumor-associated plasma DNA

Prostate Cancer - Prostate cancer progression slowed by primary hormone therapy

Prostate Cancer - Prostate cancer staging not aided by combined MRI and MR spectroscopy

Prostate Cancer - Prostate cancer treated by docetaxel-based regimens do not require estramustine

Protein Production - Elastin-like fusion protein was purified by microfiltration

Protein Production - Protein expression and solubility screening in E. coli were explored

Proteomics - Alterations in mitochondrial proteome of adriamycin resistant MCF-7 breast cancer cells discussed

Proteomics - Ankyrins in new context of cardiac channelopathies are focus of review

Proteomics - Coronary artery disease-related proteins are found by proteomics analysis of pooled data

Proteomics - High abundance proteins profiled in cystic fibrosis lung epithelial cells

Proteomics - Microarray platforms are useful for quantitative characterization of gene expression

Proteomics - New thioredoxin inhibitors contain hypoxia-linked protein

Proteomics - Protein computational design stereochemically optimized

Proteomics - Rab5 stimulates insulin receptor substrate-protein kinase interaction

Proteomics - Recombinant activin A purified using follistatin gene domain

Proteomics - Vascular endothelial growth factor may have an indirect effect on the pulmonary immune system

Proteomics - Vascular endothelial growth factor splice variant has attenuated signals

Psychiatry - Problems of objectivity and critique in psychoanalysis are examined

Pulmonary Hypertension - Oral therapy for pulmonary arterial hypertension with bosentan/sildenafil is safe and effective

Pulmonary Hypertension - Pulmonary embolism in patients with pulmonary hypertension signs is identified by tissue Doppler

Pulmonary Hypertension - Splenectomy a strong risk factor for pulmonary hypertension in patients with thalassemia

Rabies Vaccine - German travel health advisors need more thorough training in rabies preventive measures

Rectal Cancer - Rectal cancer patients benefited from addition of chemotherapy to preoperative radiotherapy

Rectal Cancer - Rectal cancer patients offered adjuvant therapy might benefit from decision aid

Rectal Cancer - Rectal cancer prognostic factors delineated

Renal Cell Carcinoma - Renal cell carcinoma prognosticated by osteopontin expression

Renal Cell Carcinoma - ZymoGenetics begins phase I/II trial of IL-21 and Nexavar in patients with kidney cancer

Renal Failure - Chronic renal failure may benefit from hypoxia response system regulation

Reovirus - New mammalian reovirus characterized

Respiratory Medicine - Binding site for Moraxella catarrhalis protein identified

Respiratory Medicine - Drug combination improves survival in patients with COPD

Respiratory Medicine - Identifying rare genetic disorder early on may minimize damage from certain lung conditions

Respiratory Medicine - Idiopathic pulmonary arterial hypertension mortality rates highest among African American women

Respiratory Medicine - Noninvasive IBV Valve is found safe and effective for COPD patients

Retinoblastoma - Metastatic retinoblastoma associated with dismal prognosis

Rett Syndrome - Case School of Medicine professor discovers nerve cell defects caused by mental retardation gene

Rett Syndrome - Researchers offer insights into activity-dependent neuronal growth through RSRF-supported research

Rheumatoid Arthritis Therapy - Cartilage oligomeric matrix protein level is used to monitor therapy in rheumatoid arthritis

RNA Interference - RNA interference library based on nuclear receptor consensus sequences reported

Salmonella Outbreaks - Extended-spectrum beta-lactamase-producing Salmonella Isangi outbreak detected in pediatric ward

Sarcoma - Sarcoma could be linked to genetic polymorphisms of XPG and XPD nucleotide excision repair genes

SARS Genetics & Genomics - Large deletion in SARS coronavirus may provide evidence for quasispecies

Schistosomiasis Vaccine - Schistosomiasis and molecular biology of male-female interaction of S. mansoni are discussed.

Schizophrenia - Aripiprazole is an effective treatment for acute agitation in schizophrenia

Schizophrenia - Correlates of P50 sensory gating abnormalities in schizophrenia patients are reviewed

Schizophrenia - Weight control for those taking clozapine should focus on energy expenditure and physical activity

Secondary Progressive Multiple Sclerosis - BioMS Medical expands pivotal multiple sclerosis trial into Finland

Serratia Marcescens Outbreaks -  Serratia marcescens meningitis outbreak caused by improper betamethasone compounding

Sexual & Reproductive Health - Exhaustive endurance exercise induces reversible fertility changes in men

Sexual & Reproductive Health - Penile venous stripping surgery-associated response failures are investigated

Sexual & Reproductive Health - Study shows patient preference for Gonal-F RFF PEN to treat infertility

Shigella Vaccine -  Shigella flexneri 2a 34 kDa outer membrane protein elicits immune response

Sinusitis - Advanced Life Sciences presents data on selected cethromycin trials

Sleep Apnea - Sleep-related breathing disorder may be signaled by soluble interleukin-6 receptor

Sleeping Sickness - Tsetse fly saliva biases the immune response to T helper cell type 2

Smallpox - SIGA announces smallpox treatment breakthrough

Smallpox Vaccine - Successful primary smallpox vaccination fully protects for a few decades

Solid Cancer - Lymphangiogenesis is a focus of emerging cancer research

Spinal Cord Injury - Sangamo collaborator reports positive preclinical data from nerve regeneration program

Sports Medicine - Electrostimulation resistance training of the plantar flexor muscles is studied

Staphylococcus Aureus Outbreaks - Methicillin-resistant Staphylococcus aureus outbreak strains in a stem cell transplantation unit not related

Staphylococcus Aureus Outbreaks - MRSA multiresistant genotype associated with local outbreak in Belgium

Stargardt Disease - National Neurovision Research Institute funds gene therapy for dry macular degeneration

Stem Cell Mobilization - Single dose pegfilgrastim enhances CD34+ stem cell mobilization in aggressive lymphoma

Stem Cell Research - Bone marrow-derived CD117+ stem cells and endothelial progenitor cells reduced with age

Stem Cell Research - Embryonic stem cells use angiogenesis growth factor for differentiation

Stem Cell Research - Essential osteoclast genes identified

Stem Cell Research - Human virus turns fat stem cells into fatter fat cells

Stem Cell Research - Mesenchymal stem cells isolated from normal appendices

Stem Cell Research - OncoMed granted fundamental patent for testing cancer stem cell therapies

Stem Cell Research - Stem Cell Innovations describes ability of PluriCells to become multiple cell types

Stem Cell Research - Stem cells from fat tissue demonstrate early success in reconstructive surgery

Stem Cell Transplantation - High-dose chemotherapy plus stem cell transplant safe and effective in relapsed Hodgkin disease

Stem Cell Transplantation - Presence of delirium following stem cell transplantation predicts mortality

Stroke - Blood biomarkers are found to predict the risk for recurrent stroke and mortality

Stroke - Continuous positive airway pressure did not benefit stroke patients

Surgical Technology - Enteral feeding catheters can be inserted endoscopically

Surgical Technology - FzioMed's antiadhesion gel effective in reducing postoperative adhesions following back surgery

Surgical Technology - Internal fracture fixation in pelvic ring and acetabular fractures is performed

Surgical Technology - Nerve microsurgical repair with intraoperative tension measurement is presented

Systemic Lupus Erythematosus - Allele in brain-derived neurotrophic factor gene prevents neurocognitive dysfunction in lupus

Systemic Lupus Erythematosus - Lupus Research Institute awards $4.5 million to explore new approaches to lupus

Testosterone Research - Testosterone levels in American men have been declining steadily over the past two decades

Thyroid Nodules - Thyroid nodules evaluated with contrast-enhanced ultrasound

Tissue Engineering - Culture with human serum facilitates tissue engineering of nasal septal cartilage

Tissue Engineering - Ectopic bone formation enhanced by mesenchymal stem cell scaffold and perfusion method

Tissue Engineering - Findings from University of Louisville, Department of Surgery in tissue engineering reported

Tissue Engineering - Massachusetts General Hospital publishes research in tissue engineering

Tissue Engineering - New findings from Middle East Technical University, Department of Biological Sciences in the area of tissue engineering published

Tissue Engineering - New findings in tissue engineering described from Georgia Institute of Technology

Tissue Engineering - Real-time system monitors cell aggregation and trajectories in rotating wall vessel bioreactors

Tissue Engineering - Recent studies from AO Research Institute add new data to tissue engineering

Tissue Engineering - Recent studies from Johns Hopkins University, Department of Biomedical Engineering add new data to tissue engineering

Tissue Engineering - Researchers at Nagoya University, Division of Surgical Oncology target tissue engineering

Tissue Engineering - Researchers from Zhejiang University, Department of Materials Science and Engineering report recent findings in tissue engineering

Tissue Engineering - Researchers' work from University Politecnica of Catalunya focuses on tissue engineering

Tissue Engineering - Studies from Tsinghua University, Department of Biological Sciences and Biotechnology add new findings in the area of tissue engineering

Tissue Engineering - Three-dimensional tissue-engineered bone fabricated in a rotating bioreactor

Tobacco Use - Cigarette smoking is associated with disturbances in sleep architecture

Tobacco Use - Smoking cessation therapy may be harmful for smokers in ICU

Toxicology - Dioxin and polychlorinated biphenyl human toxicity is reviewed

Toxicology - Molecular targets against mustard toxicity identified

Toxoplasmosis Vaccine - Mic1-3 knockout Toxoplasma gondii is efficacious against toxoplasmosis

Toxoplasmosis Vaccine - P30 peptides protect against Toxoplasma gondii infection

Transplant Medicine - CD4+ T cells stimulated by adenovirus peptides recognize cells infected with adenovirus

Transplant Medicine - Cylex ImmuKnow assay assesses immune function in transplant recipients

Traumatic Brain Injury - KeyNeurotek to start European phase II trial in traumatic brain injury

Travel Medicine - Health information given by Swiss travel agencies was examined

Travel Medicine - Pharmacists need training in travel medicine in Portugal

Travel Medicine - Risk of SARS coronavirus transmission is low aboard commercial aircraft

Tuberculosis - A large, untapped global market exists for improved TB tests

Tuberculosis & Diabetes - Rifampicin exposure strongly reduced in patients with tuberculosis and type 2 diabetes

Tuberculosis Diagnostics - Amplicor PCR has low sensitivity and high specificity for lymph node tuberculosis diagnosis

Tuberculosis Diagnostics - False positive Mycobacterium tuberculosis cultures detected by DNA fingerprint

Tuberculosis Epidemiology - Extensive drug-resistant tuberculosis belong to 1 of 2 epidemiological clusters in Iran

Tuberculosis Epidemiology - Tuberculosis infection prevalence high among young child contacts in Malawi

Tuberculosis Vaccine - Helminths could influence TB vaccine effectiveness in tropics

Tuberculosis Vaccine - Phagosome maturation arrest by tuberculosis vaccines interfere with processing macrophages

Tumor Hypoxia - Tumor hypoxia studied by measuring partial oxygen pressure using OxyLite system

Tumor Research - Study offers an innovative profile of enzyme that aids tumor growth

Type 1 Diabetes - Heart resistance to ischemia is higher in short-term type 1 diabetes with severe hyperglycemia

Type 2 Diabetes - In type 2 diabetes mellitus, interleukin-6 may be a complementary biomarker

Type 2 Diabetes - In type 2 diabetes, elevated NT-proBNP is a predictor of excess cardiovascular mortality

Type 2 Diabetes - U.S. FDA approves Januvia, the first and only DPP-4 inhibitor available U.S. for type 2 diabetes

Ulcerative Colitis - U.S. FDA expands Remicade indication for ulcerative colitis

Urology - Artificial urinary sphincter is successful in children and adolescents

Urology - Botox is injected into the urethral sphincter of children with non-neurogenic neurogenic bladder

Urology - Cystographic bladder capacity in children reference ranges are determined

Urology - Dextranomer/hyaluronic acid injection-associated obstruction is investigated

Urology - Familial vesicoureteral reflux risk factors for renal scarring are determined

Urology - Pelviureteric junction obstruction is treated using laparoscopic pyeloplasty

Urology - Penile urethral strictures treated by visual internal urethrotomy are assessed

Urology - Urinary incontinence is treated with endoscopic injections of a dextranomer

Urothelial Cancer Vaccine - Expression of cancer-testis antigens and survival in urothelial cancer was examined

Uveal Melanoma - Uveal melanoma survival predicted by monosomy 3 and largest tumor diameter

Vaccination - T cell conditioning explains early disappearance of CD8 T cell response to infection

Vaccine Adjuvant - CpG oligodeoxynucleotides improve efficacy of Japanese encephalitis vaccine

Vaccine Adjuvant - Fetal intestinal epithelial cells were used in screening assays to identify immune system adjuvants

Vaccine Safety - No direct role has been found for SV40 in human cancer

Vaccinia Virus - Envelope G3L protein essential for entry of vaccinia virus into host cells

Vaccinia Virus - New findings in vaccinia virus described from John Radcliffe Hospital

Vaccinia Virus - Researchers at Thomas Jefferson University publish new data on vaccinia virus

Vaccinia Virus - Vaccinia virus M2L protein inhibits NF-kappa 13 activation induction via an ERK2 pathway

Varicella-Zoster Virus Epidemiology - Varicella-zoster virus seroprevalence estimates associated with age and place of origin

Varicella-Zoster Virus Vaccine - Live attenuated varicella vaccine safe and immunogenic in children with atopic dermatitis

Varicella-Zoster Virus Vaccine - Memory T cell immunity to varicella-zoster virus in healthy adults differs by gender

Vector Development - Integration profile of equine infectious anemia virus-based vectors is presented

Vector Development - Lentiviral in situ vector delivery enabled gene transfer into adult stem cells

Vesicoureteral Reflux Therapy - Vesicoureteral reflux management in era of dextranomer/hyaluronic acid copolymer is reviewed

Virology - Epstein-Barr protein allows efficient transfer from endosome to nucleus of B lymphocytes

Virology - Herpes simplex virus type 1 nuclear capsid egress reconstituted in vitro

Virology - Human papillomavirus genotyping tests were evaluated

Virology - Researchers at University of Pennsylvania, Microbiology Department target virology

Virology - Retrovirus involved in tumor progression studied in vivo

Virology - Retrovirus particles mobilize full-length Semliki Forest virus replicon

Virology - Vaccinia virus F9 virion membrane protein is needed for entry but not virus assembly

Virology - Virus invasion of host cells identities a novel role for caveolae

Zollinger-Ellison Syndrome - U.S. FDA approves Nexium for treatment of Zollinger-Ellison Syndrome

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