Diabetes Control

Diabetic nephropathy genetically controlled in a mouse model

Published in Biotech Law Weekly, November 17th, 2006

A study from Japan has reported on the genetic control of diabetic nephropathy in a mouse model.

"Nephropathy is a major microvascular complication in long-standing diabetic patients who eventually undergo renal dialysis or transplantation. To prevent development of this disease and to improve advanced kidney injury, effective therapies directed toward the key molecular target are required.

"In this study, we examined whether inhibition of the receptor for advanced glycation end products (RAGE) could attenuate changes in the diabetic kidney," wrote K.M. Myint and colleagues, Kanazawa University.

"Here, we show that inactivation of...

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Source: Biotech Law Weekly (2006-11-17)

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