Multiple Myeloma

First tandem autotransplant trial long-term outcomes are assessed

Published in Biotech Law Weekly, November 17th, 2006

Long-term outcome results of the first tandem autotransplant trial for multiple myeloma are assessed.

"Total Therapy 1, the first tandem autotransplant trial for newly diagnosed patients with multiple myeloma, was designed to increase the frequency of complete response (CR) and thereby extend survival. With a median follow-up of 12 years, 62 of 231 initially enrolled patients are alive (17% at 15 years); 31 remain event free (7% at 15 years) including 16 of 94 (41%) that initially achieved CR," according to investigators in the United States.

"Currently alive patients less frequently had cytogenetic abnormalities (CAs) at baseline (p=.002),...

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Source: Biotech Law Weekly (2006-11-17)

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