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Microbiology

Research conducted at University of Maryland, Maryland Biotechnology Institute has provided new information about microbiology

Published in Biotech Law Weekly, March 23rd, 2007

New investigation results, "RNAi-based tuning of cell cycling in Drosophila S2 cells--effects on recombinant protein yield," are detailed in a study published in Applied Microbiology and Biotechnology. According to recent research from the United States, "We have demonstrated the RNA interference-based interruption of cellular controllers to increase recombinant protein yield in Drosophila Schneider 2 (S2) cell culture. Double-stranded RNA (dsRNA) was enzymatically synthesized in vitro and transfected into stable cell lines expressing green fluorescent protein (GFP) under an inducible promoter."

"Components of cell cycling (CycE and ago) were silenced with dsRNA...

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