Influenza
New findings from I. Stephenson and co-researchers in the area of influenza described
Published in Biotech Law Weekly, August 31st, 2007
"A study was performed to investigate the reproducibility of haemagglutinin-inhibition (111) and virus neutralising (VN) assays for detection of anti-influenza antibody. Participants in I I laboratories from eight countries measured antibody to ego-grown A/Japan/434/2003, cell-grown A/Japan/434/2003 and A/Panama/2007/99 (H3N2) viruses in 18 human and two post-infection ferret sera," scientists writing in the journal Vaccine report.
"There was significant intra-laboratory assay variability for VN compared to HI. For replicate assays within laboratories, 14/410 (3%) and 130/631 (21%) fitres differed by > 2-fold (p < 0.0001), and 0/410 (0%) and 35/631 (6%)...
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Source: Biotech Law Weekly (2007-08-31)
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