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Intranuclear Space

'Synthetic' chromosome permits repid, on-demand 'evolution' of yeast

Published in Biotech Law Weekly, September 30th, 2011

2011 SEP 30 -- In the quest to understand genomes-how they're built, how they're organized and what makes them work-a team of Johns Hopkins researchers has engineered from scratch a computer-designed yeast chromosome and incorporated into their creation a new system that lets scientists intentionally rearrange the yeast's genetic material. A report of their work appears September 14 as an Advance Online Publication in the journal Nature.

"We have created a research tool that not only lets us learn more about yeast biology and genome biology, but also holds out the possibility of someday designing genomes for specific purposes, like making new vaccines or...

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