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Canji Inc.
Multiple cycles of p53 gene therapy may inhibit recurrent ovarian tumors
May 14th, 2003
Multiple cycles of p53 gene therapy may inhibit recurrent ovarian tumors. "A cohort study was designed to evaluate the efficiency of gene transfer and whether biological activity from the expressed therapeutic gene resulted after administration of a recombinant adenovirus containing the human wild-type p53 (p53(wt)) gene (rAdp-53 SCH 58500)," scientists writing in the journal Cancer Gene Therapy reported. "The cohort study was conducted in five trial subjects with recurrent ovarian cancer. Each trial subject received multiple cycles of rAd-p53 SCH 58500, each cycle comprised of doses of 7.5 x 1013 particles on each of five...
Source: Biotech Week (2003-05-14)
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