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DynPort Vaccine Co.



Phase I smallpox vaccine clinical trial completed



May 14th, 2003

Computer Sciences Corporation (CSC) announced that DynPort Vaccine Company LLC (DVC), a joint venture between CSC and Porton International, a vaccine development company focused on biodefense vaccines, has completed phase I testing of the safety and immunogenicity of an improved cell-cultured smallpox vaccine (CCSV).

In this trial, 100% of 350 volunteers exhibited a positive response to either the CCSV or the historic calf lymph-produced smallpox vaccine (Dryvax). However, the incidence of vaccine-related fatigue, application site rash, increased temperature, headache, lymphangitis and nausea was at least 8% less common for volunteers receiving CCSV than Dryvax.

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Source: Biotech Week (2003-05-14)

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