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Susan Hasty, Publisher Table of Contents . . . July 30th, 2003 Non-Subscriber - Summaries Only Related Areas: Other Issues in Biotech Week | Other Publications
Asahi Kasei Corp. - New mechanism reverses diabetes symptomsOxford BioMedica - Phase I/II trial results look good so far in breast cancer patientsChiron Corp. - Gag and Pol antigens are important for effectiveness of AIDS vaccinesEraGen Biosciences - Two technologies used to study SARSNeurocrine Biosciences, Inc. - Positive phase I trial reported with orally active GnRH receptor antagonistNorthwest Biotherapeutics, Inc. - CXCR-4 clinical antibodies identifiedAGA Medical Corp. - Study compares Amplatzer PFO Occluder and standard drug treatmentARIAD Pharmaceuticals, Inc. - New generation of treatments shows promise for cancer patientsAarhus University of Hospital - PAI-1 production higher in adipose tissue from obese women than in lean womenAastrom Biosciences, Inc. - Third NIH grant received during fiscal quarter for stem cell researchAbbott - Asset purchase of coronary and peripheral business line completeAcademy Sinica - Breast cancer may be initiated by estrogen exposure, which causes DNA DSBsAccelrys - Catalyst 4.8 released for lead identification, optimizationAccentia, Inc. - Controlling interest of cancer vaccine company acquiredAdvanced Magnetics, Inc. - Imaging agents producer to sell $10M in common stockAgennix, Inc. - Young named chairman of board of directors at biotech firmAkers Biosciences, Inc. - Alliance to promote rapid test for cardiology markerAlbert Ludwigs University - Growth factor promotes new blood routes in rat brainAlnylam Pharmaceuticals, Inc. - Ulich named head of R&D at pharmaceutical firmAmerican Foundation for AIDS Research - amfAR awards $1.5 million for basic research into HIV/AIDSAmerican Pharmaceutical Partners, Inc. - ANDA approval granted for valproate sodium injectionAmgen - First biologic recommended by FDA panel for inflammatory diseaseAntares Pharma, Inc. - Plans at pharmaceutical firm continue following move of shares to OTCBBAntiCancer, Inc. - Methioninase gene therapy causes apoptosis in bcl-2-expressing lung cancersApple Computer - Medidata announces EDC support for Safari browserAstraZeneca - Novel automated method aids busulphan monitoringAtrix Laboratories, Inc. - Patent extends Eligard product protection to 2018Atugen AG - Second generation synthetic siRNAs will be better suited for gene silencingAventis Pasteur - Global poliomyelitis eradication and vaccination strategies reviewedBarrier Therapeutics, Inc. - TrialMaster selected as EDC solution for seborrheic dermatitis trialsBates College - Ubiquitin systems tilt toward recognition of hepatitis A virus 3D polymeraseBaylor College of Medicine - Chimeric influenza HA/SHIV virus-like particles show promise for mucosal immunizationBaylor College of Medicine - Neural adhesion molecule is upregulated in perineural prostate cancer invasionBaylor College of Medicine - Novel method improves detection of fetal cells in maternal bloodBeckman Coulter, Inc. - A precursor of PSA detects more aggressive diseaseBecton Dickinson - FDA OKs new device to manage diabetesBen Gurion University of Negev - Microspheres containing growth factor improve alginate scaffold vascularizationBiorthex, Inc. - FDA approves start of clinical study on Actipore PLFxBoston Scientific Corp. - Mid-year update provided by drug-eluting stent makerBotanical Garden, Berne - New study finds agricultural biotechnology encourages biodiversityBrigham & Women's Hospital - Autoimmune optic neuritis may target myelin oligodendrocyte glycoproteinBrown University - Taurolidine has differing effects on adherent and floating melanoma cellsBurnham Institute - Hepatitis B interacting protein is a link between apoptosis and liver cancerBurrill & Company - Biotech continues to show strength in JuneCHU Lille - The mu opioid receptor has strong anti-inflammatory control in colitis modelsCHU Nancy Brabois - Electromagnetic interferences for implantable defibrillators are numerousCTRC Institute Drug Development - AMD473 (ZD0473) exhibits marked in vitro anticancer activity in human tumorsCaliper Technologies Corp. - Early termination of waiting period requested for acquisitionCardioTech International, Inc. - Fifty-one percent reduction in fiscal 2003 loss reported by device companyCase Western Reserve University - Cytokine phenotype analysis can aid genetic susceptibility studyCase Western Reserve University - Gestational diabetes may be contributor to adolescent obesityCase Western Reserve University - Interleukin-2 immunotherapy ineffectiveCase Western Reserve University - MR slice-to-volume registration can accurately aid image-guided therapyCase Western Reserve University - New gene discoveredCatholic University - Lipid and protein oxidation promote prothrombotic state in diabetic patientsCatholic University, Leuven - Novel liquid chromatography methods improve erythromycin monitoringCatholic University, Louvain - SOX18 transcription factor is fundamental to blood and lymph vessel developmentCelgene Corp. - Focalin LA pivotal clinical trial initiated in adults with ADD/ADHDCenter Hosp. Regional Gilles de Corbeil - French patients with type 2 diabetes possess high risk of cardiovascular diseaseCenters for Disease Control and Prevention - Chloroquine therapy fails to prevent malaria during pregnancyCenters for Disease Control and Prevention - DNA vaccines for the rabies-related virus, Mokola, comparedCenters for Disease Control and Prevention - Routine cycling of antimicrobial agents may protect patientsCentre Hospitalier Universitaire (CHU) de Caen - Hypermutable Staphylococcus aureus strains common in patientsCentre National de la Recherche Scientifique - Peptide gene delivery with gp41 shows promiseCentro Nacional de Biotecnologia - AIDS vaccination strategy induces significant cellular immune responsesCephalon, Inc. - Sullman named VP of regulatory affairs-EuropeCepheid - VP general counsel, and VP regulatory/clinical affairs appointed at biotech firmChang Gung Memorial Hospital - Hepatitis C virus predominates among triple-infected patients in TaiwanChildren's Hospital - Some children with chronic hepatitis B carry a rare viral mutationChina Medical College - Erythromycin improves esophageal and gastric motility in diabetic patientsChoice Media, Inc. - Marketing campaign launched for pharmaceutical companiesCholestech Corp. - Complaint served in allegation of infringement on measurement of HDL cholesterolCiphergen Biosystems, Inc. - Diagnostic biomarker discovery program initiatedClemson University - A fusion protein with prolactin and angiogenesis antagonists snuffs out cancerCleveland Clinic Foundation - Gamma scintillation meter can detect pulmonary seed embolizationCleveland Clinic Foundation - Three techniques can stabilize the acromioclavicular jointCohesive Technologies, Inc. - $9.5M Series B round completed by bioanalytical testing companyColumbia University College of Physicians & Surgeo - Genetic analysis identifies putative tumor suppressor sitesConnetics Corp. - New drug application submitted for ExtinaConnetics Corp. - Olux approved for marketing in the United KingdomCorgentech, Inc. - Biotech firm completes move to new headquartersCorixa Corp. - FDA approves BexxarCornell University - Interferon regulatory factor-1 may be linked to cerebral ischemia and strokeCornell University - Miniature biolab embedded on silicon chipCreighton University - Molecular and genetic mechanisms of obesity reviewedCropLife American - Cumulative exposure to organophosphate pesticides assessedCryo-Cell International, Inc. - Biotech firm engages auditorsCyberonics, Inc. - CE Mark approval granted to market VNS therapy systemCytRx Corp. - CytRx licenses RNAi technologyDOV Pharmaceutical, Inc. - Equity investment made in CNS drug companyDeakin University - Dopamine receptor gene Taq IA/Ser311Cys polymorphisms not linked to obesityDept. of Veterans Affairs Medical Center, Philadel - Both reactivation and reinfection responsible for MAC infection in macaquesDuke University - APOE genotype is risk factor for neuropathy severity in diabetic patientsDxS Ltd. - Genotyping sample collection system launchedEDAP TMS S.A. - Ultrasound technology remains helpful for prostate cancer applicationEchelon Biosciences, Inc. - NIH grant awarded to counter global threatElan Corporation plc - Pharmaceutical firm to file for extension to file report on form 20-FElitra Pharmaceuticals - Hamelin named CEO at antibacterial drug companyEncore Medical Corp. - Clemow joins board as director at orthopedics medical device firmEndo Pharmaceuticals Holdings, Inc. - Secondary offering of common stock priced for pharmaceutical firmEndocare, Inc. - Status on audit, SEC filings provided by medical device companyEntropin, Inc. - Pain drug maker notified of NASDAQ delistingEpimmune, Inc. - International HIV vaccine trial under way in Africa and the United StatesErasmus Medical Center - Lamivudine reduces hepatitis B virus vertical transmission riskEsperion Therapeutics, Inc. - Multiple-dose study of ETC-642 (RLT Peptide) beginsEukarion, Inc. - Compounds reverse age-related learning deficits in miceEunoe, Inc. - Alzheimer disease device company closes $40M private placementEurand - AdvaTab fast dissolve technology launchedEvotec OAI - Medicinal chemistry agreement signed for development of kinase targetFIRC - Some cytokines inactivate VEGF signals by controlling its receptorsFemmePharma, Inc. - Women's prescription pharma company secures round of financingFinnish Red Cross and Blood Transfusion Service - Apotransferrin can prevent Staphylococcus epidermidis infectionsFlexcell International - Researchers share new insights into degeneration of knee jointsFood and Drug Administration - Francisella novicida LPS more immunogenic than F. tularensis LPSFood and Drug Administration - Brain neuronal degeneration occurs after single Ecstasy exposureFood and Drug Administration - Catechol from hair dyes is absorbed through the skinFood and Drug Administration - Correlates of immunity for pneumococcal conjugate vaccines discussedFood and Drug Administration - Enterotoxigenic El Tor-like hemolysin produced by Vibrio fluvialis Food and Drug Administration - Flaxseed increases alpha-linolenic and eicosapentaenoic acid in ratsFood and Drug Administration - Flaxseed reduces levels of linoleic and arachidonic acids in ratsFood and Drug Administration - Oligohydrosis and fever reported in children treated with zonisamideFood and Drug Administration - Pancreatic tumors become susceptible to toxin when made to express IL-13Ralpha2Food and Drug Administration - Rat fetal development not affected by diet high in flaxseedFood and Drug Administration - The molecular and serological aspects of North American HBV infections varyGelderse Vallei Hospital - Reversible acute renal failure seems to occur occasionally, due to hematuriaGenentech - Genaera announces early conversion of series A convertible preferred stockGenentech, Inc. - FDA approves first humanized antibody that targets IgEGenetic Technologies - 'Junk DNA' pioneer hits back at criticsGenmab A/S - Commercial option exercised for HuMax-IL15Genta, Inc. - FDA grants fast track designation for Genasense in CLLGenzyme Corp. - Company completes transaction to eliminate tracking stocksGeorgetown University - Putative niche identified for murine mammary epithelial stem cellsGeorgetown University - The effects of metals may be mediated through the hormone-binding domainGhent University Hospital - Class I homeobox genes play key role in T cell developmentGlaxoSmithKline, plc - Company asks FDA to remove three Paxil patents from Orange BookH Lee Moffitt Cancer Center & Research Institute - EH polymorphisms are important in the risk of orolaryngeal cancer in CaucasiansHacettepe University - Transient intrauterine hypotension affects fetal rat brains and later learningHackensack University Medical Center - Combination cryoprotectant solution improves outcomeHannam University - Metabolic-resistant starch lowers blood lipids in diabetic ratsHarvard University - Computer wizardry aids the development of human angiogenin antagonistsHarvard University - Researchers engineer trachea using sheep nasal chondrocytes and epithelial cellsHealth Reviews Ltd. - All pertussis vaccines are efficacious in childrenHoffmann-La Roche, Ltd. - Suit to be filed on behalf of victims of Accutane side effectsHokkaido University - Vaccine with fusion cells of dendritic and carcinoma cells halts tumor growthHuddinge University Hospital - Post-transplant G-CSF linked to higher graft-versus-host disease riskHumboldt University - Lipotechoic acids activate innate immune system using TLR-2, LBP, CD14Humboldt University - Niemann-Pick and Alzheimer disease have tangled neurons with high cholesterolHumboldt University - Plasma-based titrations can miss the full extent of adenovirus circulationINSERM - High levels of mutant integrase can overcome defectsINSERM - VEGF falls short for predicting outcomes in certain metastatic breast cancersIbis Reproductive Health - Studies report EC works up to 120 hours and in different combinationsImmuneRegen BioSciences - GPN Network finalizes mergerImperial College of Science Technology and Medicin - Muscle satellite cells show prospective use for regeneration and gene therapyInformatica Corp. - FDA streamlines vaccination, drug-reporting systemsInnsbruck University - Viral proteins interact with several Candida speciesInstitut Paoli-Calmettes - CD111 expression by immature hematopoietic progenitors characterizedInstitute Gustave Roussy - Hepatocellular carcinoma is controlled with enzyme inhibitorsInstitute for Clinical and Experimental Medicine - Cytokine regulation in the kidneys disrupted in type 1 diabetesInstitute of Cancer Research - New fusion proteins use VEGF to target therapy towards tumorsInstitute of Clinical Neurobiology - More postmortem cerebrovascular lesions appear unrelated to cognitive impairmentInstitute of Diabetes 'Gerhardt Katsch' - Troglitazone therapy prevents type 1 diabetes in miceInstituto Mexicano del Seguro Social - Nateglinide offers effective control of type 2 diabetesIntegrated BioPharma, Inc. - Company completes $9.5 million private placementIntegrium - Research organization to use VillageEDOCS desktop broadcast fax servicesInterMune, Inc. - Class action lawsuit filed against biotech firmIntermune Inc. - EGF can protect ME180S cells from TNF-alpha-induced apoptosisInternational Centre for Genetic Engineering and B - Effects of DNA-binding agents on plasmodial DNA helicase characterizedInverness Medical Innovations, Inc. - Women's health company completes acquisition of OstexJONES Group/JMI Laboratories - Incidence of fluoroquinolone-resistant influenza risingJONES Group/JMI Laboratories - Patient age influences streptococcal drug resistance profilesJames Cook University - Group A streptococcal M protein peptides induce autoimmune valvulitis in ratsJinju National University - Conjugated linoleic acid promotes beta-cell viabilityJohns Hopkins School of Medicine - Telomere shortening may be early marker of cancer activityJohns Hopkins University - A novel hypoxia-inducible factor is both vasoconstrictive and angiogenicJohns Hopkins University - HCV infection raises the risk for type 2 diabetes in predisposed individualsJohns Hopkins University - Heat shock protein 60 binds the MHC-Ia's Qa-1, but not on peptide QdmJohns Hopkins University - JC virus infection increases risk of adult astrocytic brain tumorsJohns Hopkins University - KLF4, a cell cycle checkpoint protein, can reduce tumorigenicity of colon cancerJohns Hopkins University Hospital - Distinct pathways of carcinogenesis may exist for serous carcinoma of the ovaryJohnson & Johnson - Formic acid pretreatment may overenhance amyloid plaque, heat does notJuntendo University - Energy expenditure associated with body surface area in girls with anorexiaKagawa Medical University - Neural-cadherin expression associates with angiogenesis in lung cancer patientsKalypsys, Inc. - John McKearn named chief scientific officer of biopharma firmKanazawa Medical University - IL-6 in synovium may be related to the grade of joint effusion in jawKansas State University - Lens epithelial cell survival is enhanced by LEDGF activation of PKC gammaKarolinska Institute - Waiting too long between pregnancies increases risk, study findsKenyatta University - IFN-gamma response to malaria vaccine linked to improved hemoglobin levelsKhon Kaen University - Novel antimalarial agents derived from Thai medicinal plantKings College Hospital - Autoimmune liver disease in children may lead to cholangiopathyKyoto University - Blood glucose can be controlled under continuous glucose challengeKyungpook National University Hospital - High CD34 cell dose linked to heightened GVHD risk but improved survivalKyushu University - PBD pathogenic gene for CG8 malfunction is restored with PEX26LKH - Computerized heart monitoring can indicate the need for biopsyLaboratory Management Systems, Inc. - Pharmaceutical compliance firm to use Documentum platformLaval University - Sst I polymorphism linked to high triglycerides in viscerally obese menLeicester Royal Infirmary - Therapies that control gelatinases may control malignant mesotheliomaLudwig Institute for Cancer Research - CD8 facilitates binding of the MHC-I peptides to the T cell receptorM.D. Anderson Cancer Center - A new skin cancer model should contribute to the study of antiangiogenic therapyMP Global Enterprises - ICN Pharmaceuticals announces sale of biomedicals businessesMahidol University - Subtype B and E gp120-based vaccines safe and effective for Thai recipientsMassachusetts General Hospital - Hepatitis C virus clears spontaneously upon immunosuppression discontinuationMaxim Pharmaceuticals - Preliminary results of two additional clinical trials of Ceplene announcedMayo Clinic - Measles virus producing carcinoembryonic antigen fights glioblastomaMayo Clinic - Post-transplant CMV replication not completely inhibitied by oral ganciclovirMayo Clinic and Mayo Foundation - Angiogenic cytokine is overexpressed in myelofibrosis with myeloid metaplasiaMead Johnson Nutritionals - Study supports adding nutrients to infant formulas through the first yearMedical College of Georgia - The human placenta is found to actively metabolize fatty acids with many enzymesMedical College of Wisconsin - Cell dose in HLA-matched grafts influences treatment outcomeMedical Research Council - Novel oligonucleotide has strong RNA binding but limited efficacyMedical Services International, Inc. - Medical Services begins to fill contracts for VScan HIV Test KitsMemorial Sloan-Kettering Cancer Center - Patterns of nontuberculous mycobaterial infection characterizedMerck Research Laboratories - Lack of dipeptidyl peptidase IV protects mice against obesityMicroIslet, Inc. - Juvenile Diabetes Research Foundation to fund encapsulation technologyMie University - Therapeutic drug monitoring of vancomycin improves efficacyMologen - Berlin biotech starts clinical trial of a MIDGE-based DNA vaccineMorphotek, Inc. - Patent issued for platform technology to develop classes of antimicrobial agentsMyogen, Inc. - Colorado biopharmaceutical company announces cardiac application of HDACNaPro BioTherapeutics, Inc. - Collaborations advance sickle cell programNaPro BioTherapeutics, Inc. - Life-science company announces results of shareholder meetingNanotechnology - U.K. to make multi-million dollar investment in development
National Cancer Institute - All available short tandem repeats in the human MHC have been mappedNational Cancer Institute - DNA damage response is attenuated in TGFalpha/c-myc miceNational Institute for Public Health and the Envir - Poliovirus is excreted in feces of poliovirus receptor-transgenic miceNational Institute of Health Science - Dimerizer systems appear best for adenovirus-mediated gene inductionNational Institute of Health Sciences - The adenovirus type 35 vector shows good transfection of CD34+ cellsNational Institute of Longev Science - Beta amyloid resorption and degradation appears to occur only in astrocytesNational Institute on Aging - Fasting improves glucose metabolism and neuronal resistance to injuryNational Institutes of Diabetes and Digestive and - Allele linked to diabetes in Pima Indians mediated by obesityNational Tumor Institute - Gene therapy reverses the malignant phenotype of ovarian cancer cellsNautilus Biotech - Biotech company announces private financingNeurochem, Inc. - Promising findings reported from Alzhemed phase II studyNikon Instruments, Inc. - Coolscope eliminates eyepieces, adds ease-of-useNippon Medical College - T cell response to live bacillus Calmette-Guerin mediated by CD1 moleculesNizwa Hospital - Reconstruction of the radius with a radiofibular plate and K-wire is successfulNonlinear Dynamics - Bioinformatics company hires western regional sales managerNorthwestern University - HRG/M sequences are sufficient to sensitize MCF-7 cells to doxorubicinNovaDel Pharma, Inc. - European buccal aerosol spray patent grantedNovavax, Inc. - FDA extends review time for EstrasorbNovozymes - Danish biotech firm acquires U.S.-based RootsNuvelo, Inc. - Phase II clinical trial begins using alfimeprase for acute PAONymox Pharmaceutical Corp. - "Buy" recommendation initiated for diagnostics firmOhio State University - Downregulation of PPARgamma is a key event in many types of thyroid neoplasiaOita Medical University - Leptin may be associated with invasiveness in functional pituitary adenomasOpen University - Diet can reduce antiretroviral-induced fat redistributionOrtho-McNeil Pharmaceutical, Inc. - Company reports that ORTHO EVRA patch is popular with consumersOttawa Health Research Institute - Secretory proprotein convertases activate VEGF-C to spark tumorigenesisPRA International, Inc. - Key managers promoted at clinical research organizationPain Therapeutics, Inc. - Pivotal phase III study of Oxytrex launchedPanBio Ltd. - FDA clears first diagnostic testPasteur Institute - P. falciparum liver-stage Ag-3 protective in monkeysPenn State University - Diverse Plasmodium vivax populations seen in ThailandPeregrine Pharmaceuticals, Inc. - Pharmaceutical firm reports net loss of $0.10 per sharePfizer - COX-2 inhibitor may boost treatmentPittsburgh Life Sciences Greenhouse - Executives attracted to Pittsburgh for biotech greenhousePluristem Life - Israeli biotech company acquired, including a key bioreactorPontificia Universdad Catolica de Chile - Emergency contraceptive levonorgestrel won't stop postfertilization activityPoznan School of Medicine - Exendin-4 administration improves glucose metabolism in diabetic ratsProcter & Gamble - FDA approves Prilosec for over-the-counter saleProvid Pharmaceuticals, Inc. - Pharmaceutical firm, Duke University announce drug discovery alliancePurpan Hospital - Declining blood factors send physiological signals at the end of pregnancyRJ Reynolds Tobacco Co. - Researchers identify 13 more carcinogens in cigarette mainstream smokeRPS - Boylan named VP, acquisitions and global initiativesRTIN Holdings - Pharmacy chain, healthcare information technology firm purchasedRadiometer Medical - Monitor makes continuous monitoring of O2 and CO2 easierRanbaxy Pharmaceuticals, Inc. - Generic alternative to Cytovene approved by FDARegional Hospital, Varese, Italy - FAS/APO-1 is high in inflammatory response syndrome; doesn't predict outcomeRice University - BRCA2 has a role in recombination-mediated double-strand DNA break repairRigshospitalet - CD28 expression on CD4 cells may be useful progression markerRigshospitalet - Detergent extracts of tissue can be used in immunoassays for urokinase, PAI-1Rigshospitalet - Effect of immigration on epidemiology of hepatitis B in Denmark reportedRockefeller University - Virus-specific plasma dendritic cells produce IFN, resist cytopathic effectRoyal Brisbane Hospital - No long-term adverse effects linked to donationRoyal Brisbane Hospital - Pegasys twice as effective as current standard therapyRoyal Free Hospital - HLA-DPB1 matching reduces GVHD risk but heightens relapse rateRoyal Gwent Hospital - Review of diabetic neuropathies publishedRoyal Marsden Hospital - Thalidomide has moderate activity against chronic but not acute GVHDRudjer Boskovic Institute - Endogenous p21 status predicts human tumor cell response to wild-type genesRussian Academy of Science - Patients have higher amylolytic activity in their IgM and IgG antibodiesRutgers University - NIH awards millions to Rutgers for genetics researchSEQUENOM, Inc. - Genetics company sells MassARRAY technology to the University of Hong KongSalk Institute - HIV inactivates the body's cellular smart bombSangamo BioSciences, Inc. - Gene-expression company announces R&D management changesSanofi-Synthelabo - Older drug could have exciting new roleSchepens Eye Research Institute - Cells covering the iris stops damaging inflammationSchering AG - European committee grants positive opinion on survival claim for MabCampathSchering-Plough Research Inst. - Expression of type I interferon in pancreatic islets induces diabetes in miceScion Pharmaceuticals, Inc. - Georges Haas, PhD, joins pharmaceutical company's board of directorsScottish Center for Infection and Environmental He - Sexual transmission supercedes occupation for dental worker GBV-C infectionsSecond University of Naples - Weight reduction improves endothelial functions in obese womenSenetek, PLC - Cherry Tree Development to help find licensees for InvicorpSenomyx, Inc. - Kent Snyder named president and CEOSeoul National University - Polyethylene glycol augments the effects of liposome-mediated gene transferSeoul National University - Tamoxifen induces apoptosis in breast cancer cellsSeoul National University - Tumor suppressor genes show a gene type-specific methylation profileSeoul National University Hospital - Transplanted human neural stem cells replace lost brain cells in ratsSerenex, Inc. - Chemoproteomics company expands management teamSerono, S.A. - Promising results announced for EmfilerminShenzhen New Industries - LaserSight signs agreement with Chinese strategic partnerShin Kong Wu Ho Su Mem Hospital - Angiopoietin-1 and VEGF have synergy for reversing acute hindlimb ischemiaShinshu University - Video cystoscope enables digital pictures and high-frequency cauterizationShire Pharmaceuticals Group plc - Once-daily Adderall XR provides all-day symptom control for childrenSlotervaart Hospital - Large number of inexplicable subtherapeutic drug levels observedSouthampton University Hospital Trust - Somatic mutation in V-H genes leads the way from MGUS to multiple myelomaSpanish National Cancer Center - PDGF signal regulation might be suitable for treating stroke patientsSt. George Hospital - Moles or nevi may be senescent clones of melanocytesSt. Jude Children's Hospital - Total body irradiation conditioning effective for pediatric histiocytic disease patientsStanford University - Expression of the bacterial virulence gene cagA was repressed by acid exposureStanford University - RNA interference suppresses HBV replication in cell cultures and animal liverState University of New York - Cryptosporidium infection may be cause in veterinary science studentsState University of New York - Relationship between obesity and metabolic syndrome reviewedSuperGen, Inc. - Study of Dacogen (decitabine) in combination with carboplatin launchedSwiss Medica, Inc. - Global Path changes nameTGen - Gene-expression profiling in human cutaneous melanoma profiles genetic changesTargacept, Inc. - Company wins SBIR grant for Wake Forest collaborationTarget Therapeutics/Boston Scientific Corp. - Advanced imaging techniques key for optimal treatment decisionsTayside University Hospital - Linezolid use reduces overall costsTel Aviv University - Novel inhibitory antibodies isolatedTemple University - Viral Tat regulates MCP-1 transcription through TGFbeta-1 pathwayTeranode Corp. - NIH funds Teranode Corp. deployment of design toolsTexas A&M University - Novel enoyl reductase inhibitors effective against drug-resistant tuberculosis and malariaThe Blood Center of SE Wisconsin Inc. - Progress is being made toward diagnostics for platelet alloimmune syndromesThe Ohio State University - The genotoxic risks from erionite, mordenite may be different due to iron stateThomas Jefferson University - Protein markers could shed light on the pathogenesis of liver cancerTitan Pharmaceuticals, Inc. - Randomized phase IIb study of Pivanex in lung cancer initiatedTokai University - Notch proteins can induce T cells in a culture used for B cell developmentTokyo Institute of Psychiatry - Frontotemporal dementia neurons have positive p62 and ubiquitin inclusionsTrakya University - Molding the ears after anterior scoring and concha repositioning is successfulTyco Healthcare - SoftCare nonadhesive pulse oximetry sensor designed to protect neonatal skinUlleval University Hospital - Endothelial cells uptake zymosan particles; thus they can uptake pathogensUniformed Services University of the Health Scienc - Gene rearrangement could lead the way to a cure for systemic lupusUnited States Department of Agriculture - Aerobic exercise better at reducing heart disease risk after menopauseUniversidade Estadual de Campinas - Cultural attitudes inhibit use of protective vaginal products in BrazilUniversity "Federico II" Medical School - Atherosclerosis found in normotensive obese women with low DHEA levelsUniversity College London - Hypoxia-responsive element gene therapy targets ocular vessel growthUniversity College London - Results from largest, longest running study show ICSI and IVF are safeUniversity College London - Vector complexes formed in water enhance pulmonary gene expression in vivoUniversity Hospital Gasthuisberg - Amifostine effects are nonselective in myelodysplastic syndrome patientsUniversity Hospital Zurich - Risks of general elective surgery not increased for obese patientsUniversity Hospital, Geneva - TCR Valpha chain interactions provide broad antigen specificityUniversity of Adelaide - O antigen chains mask some IcsA (VirG) locations on cellUniversity of Adelaide - Pathogens have unique immune manipulation methods; includes chemokine subversionUniversity of Alabama - A mosaic virus strategy may improve adenoviral tropism in human gene therapyUniversity of Alabama - Effective mucosal immunity to anthrax obtainedUniversity of Alabama-Birmingham - Beta blockers useful in the patient with diabetesUniversity of Athens - Angiopoietin-1 suppresses several elements of inflammatory responseUniversity of Auckland - ICAM-1-generated antitumor immunity benefits from therapy targeting vasculatureUniversity of Birmingham - Nicotinamide N-methyltransferase is high in cerebellum; may be pathogenicUniversity of Bordeaux - The immunoglobulin-like domain of the LIF receptor modulates LIF affinityUniversity of Bristol - Human leukocyte antigen class II and autoimmune diabetes reviewedUniversity of Calgary - Trophoblast giant cells use depth of invasion to modulate angiogenic proteinsUniversity of California San Francisco - Genomic analysis can provide insight into progression of melanocytic neoplasmsUniversity of California Santa Barbara - Collagen fibrils in tendons are inhomogeneously structuredUniversity of California at Irvine - Tracking protein patterns may cut biopsy ratesUniversity of California at Los Angeles - Novispirin G-10 is active against Chlamydia trachomatis and vaginosis agentsUniversity of California at San Francisco - Sirolimus extends delayed graft function substantially after kidney transplantUniversity of California, San Francisco - Short-term study questions red clover's effect on hot flashesUniversity of California-San Francisco - Lack of acyl CoA:diacylglycerol acyltransferase 1 confers obesity resistanceUniversity of Cambridge - Schistosoma mansoni antigens prevent onset of type 1 diabetesUniversity of Chicago - Breast cancer survivors have fewer heart attacksUniversity of Cincinnati College of Medicine - Src and CD44 are potential targets for the treatment of peripheral nerve tumorsUniversity of Colorado Health Sciences Center - PPAR gamma diminishes in pulmonary hypertension and affects endothelial cellsUniversity of Copenhagen - Plasmodial dihydrofolate reductase genotype linked to drug resistanceUniversity of Dundee - Hypoxia attenuates the p53 response to cellular damageUniversity of Edinburgh - MBD1, MBD2 and CGBP genes may have only a limited role in human tumorigenesisUniversity of Edinburgh - Plasma cortisol is a predictor of plasma glucoseUniversity of Edinburgh - Recombination enzyme ERCC1 is not involved in immunoglobulin class switchUniversity of Florence - Antisense suppression of the Shaker-like KvI.I gene halts amphetamine's effectsUniversity of Florida - Radiation prolongs survival for certain patientsUniversity of Frankfurt - Glycyrrhizin shows promise for SARS treatmentUniversity of Frankfurt Klinikum - Activation of c-Jun-N-terminal-kinase is crucial for a cell cycle arrestUniversity of Freiburg Medical Center - Mesenchymal stem cells do not show telomerase activityUniversity of Goteborg - Colectomy patients have reduced response to Salmonella enterica vaccineUniversity of Gothenburg - Loss of GFAP expression in astrocytomas does not contribute to tumor developmentUniversity of Hamburg - Antithymocyte globulin-based T-cell depletion reduces GVHD rate in multiple myeloma patientsUniversity of Iowa - Mononeuritis multiplex similar to diabetic amyotrophy in diabetic patientsUniversity of Kuopio - VEGF-D is the strongest of the isoforms for gene therapy-mediated vessel growthUniversity of Lodz - Surface groups dictate polyamidoamine dendrimer molecular interactionsUniversity of Mainz - The oncolytic effect of parvovirus H1 is routed through heat shock proteinUniversity of Marburg Hospital - The human peptide antibiotic LL-37/hCAP-18 joins angiogenesis with immunologyUniversity of Maryland Hospital - Glatiramer acetate, similar to myelin basic protein, is effective MS therapyUniversity of Massachusetts - Hepatitis C virus core proteins induce pro- and anti-inflammatory cytokinesUniversity of Medicine and Dentistry of New Jersey - Tat-associated kinase may play roleUniversity of Melbourne - Scientist overturns 30 year calcium dogmaUniversity of Miami - M. tuberculosis suppresses dendritic cell maturationUniversity of Michigan Health System - Doctors implant new 'bionic ear'University of Michigan Health System - Modified sling procedure uses vaginal mesh tapeUniversity of Michigan Health System - Sleep disorders linked to faulty brain chemistry, study findsUniversity of Milan - Cladribine and 2-chloro-adenosine induce apoptosis of human astrocytoma cellsUniversity of Naples Federico II - Low-dose contraceptives have a positive effect on bone turnover in young womenUniversity of Newcastle - Mutant Kit protein linked to heightened mast cell, platelet differentiationUniversity of North Carolina - ATP modulates load-inducible IL-1 beta, COX 2, and MMP-3 expression in tendonsUniversity of North Carolina at Chapel Hill - Key step allowing cell migration describedUniversity of Otago - Prolonged immune response to antigen produced by polycaprolactone particlesUniversity of Oxford - Dectin-1 mediates the production of TNF-alpha in the antifungal responseUniversity of Paris - Novel host-parasite evolution model may elucidate malaria parasite developmentUniversity of Pennsylvania - Gene profiling uncovers the response to pulmonary hyperoxia in miceUniversity of Pennsylvania - Genes influencing human obesity found in chromosome region 7q22.1-7q35University of Perugia - Ghrelin in obese men not affected by short-term treatment with growth hormoneUniversity of Pittsburgh - Interferon-beta gene transfer accompanied by dendritic cells inhibits cancerUniversity of Pittsburgh - NF-kappa B and TNF-alpha stimulate androgen receptor expression in Sertoli cellsUniversity of Pittsburgh - TRAIL gene transfer reduces inflammatory tissues in arthritis modelsUniversity of Puerto Rico - Novel sponge-derived agents active against malaria, malignancyUniversity of Rochester Medical Center - Blood type incompatibility does not affect outcomeUniversity of Rome - Stem cells work against muscular dystrophy in miceUniversity of Rome 'La Sapienza' - Novel agents active against NNRTI-resistant virusesUniversity of Sao Paulo - Chemical restraints could regulate acidic fibroblast growth factor peptidesUniversity of Sassari - Interleukin-12 levels can predict disease progressionUniversity of Southampton - Elevated hdm2 levels play a role in development of ERalpha(+ve) breast tumorsUniversity of Tampere - CRE binding factor involved in Vpr activityUniversity of Texas - VEGF receptor 2 has clinical relevance in chronic myelogenous leukemiaUniversity of Texas Southwestern Medical Center - Drug-inducible, dendritic cell-based genetic immunization accomplishedUniversity of Toledo - Azithromycin does not affect cyclosporine A pharmacokinetics after kidney transplantationUniversity of Toronto - Control does not reduce within-subject variation of glycemic responsesUniversity of Turin - LAG-3 enables DNA vaccination to prevent breast cancer in miceUniversity of Utrecht - Clonal exhaustion results from interclonal regulationUniversity of Utrecht - IL-2 and IL-12 appear to induce different mechanisms of macrophage cytoxicityUniversity of Vienna - Hyperthermia improves immune response to human hepatocellular carcinomaUniversity of Vienna - Hypoxia stabilization factor predicts cervical cancer's response to radiationUniversity of Warwick - Screening trial finds 300 have early-stage diseaseUniversity of Washington - Hepatitis C virus nonstructural 5A protein attenuates interferon-linked signalsUniversity of Wurzburg - Details of the life cycle of coronavirus describedUniversity of Wurzburg - LIM and LASP are substrates for cGK in human plateletsUniversity of Yamanashi - Core temperature monitoring with new ventilatory devices is accurateVasogen, Inc. - Immune modulation therapy company completes private placementVela Pharmaceuticals - FDA clears R-tofisopamVeterans Affairs Medical Center, Oklahoma City - Novel murine model enables bone marrow transplantation evaluationViPS, Inc. - Healthcare information technology provider acquires CB TechnologiesViatronix, Inc. - Viatronix releases its latest software version for virtual colonoscopyVical, Inc. - Patent announced for DNA vaccines with Vaxfectin adjuvantVicuron Pharmaceuticals, Inc. - FDA accepts anidulafungin new drug application for reviewViragen, Inc. - Multiferon maker completes $5.5 million debt financingVirginia Commonwealth University - Researchers describe intraoperative dynamic dosimetry for prostate implantsVrije Universiteit Brussel - Systemic proinflammatory cytokine release linked to major transplant-related complicationsWake Forest University Baptist Medical Center - Scientists figure out bizarre visual conditionWeizmann Inst. of Science - New long-acting glucose-lowering prodrug synthesizedWeizmann Institute of Science - C-terminal octylation improves T20 efficacyWoodside Biomedical Inc. - Nerve stimulator may help relieve nausea and vomiting in pregnancyWyeth Ayerst Research - Novel orally active MMP inhibitors could knock down osteoarthritisWyeth Research - Novel compound inhibits paclitaxel- and docetaxel-resistant tumor cell linesXenova Group, plc - Phase I clinical trial of MLN944 launchedYale University - 'Tunnel' allows external continuous measurement of brain temperature
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