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Albert Ludwigs University



Growth factor promotes new blood routes in rat brain



July 30th, 2003

Injections of a stimulant agent into rat brains expanded blood vessels and improved blood flow, a finding that may lead to a new, noninvasive way to prevent stroke, researchers report.

Rats treated with the growth-promoting substance granulocyte macrophage-colony stimulating factor (GM-CSF) had almost twice as much arteriogenesis, the expansion of a brain artery, after 1 week compared to rats given saline solution. The increase was associated with improved circulation and accumulation of cells that are thought to play a key role in artery development.

"To the best of our knowledge, this is the first report of stimulation of arteriogenesis in the...


Source: Biotech Week (2003-07-30)

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