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Baylor College of Medicine



Neural adhesion molecule is upregulated in perineural prostate cancer invasion



July 30th, 2003

Neural adhesion molecule is upregulated in perineural prostate cancer invasion.

According to published research from the United States, "Currently postulated mechanisms of perineural invasion (PNI) include interaction between tumor cells and nerves. Neural cell adhesion molecule (N-CAM), one of the well-known members of the immunoglobulin super-family of adhesion molecules, was implicated in PNI and metastasis in various types of cancer.

"Tissue microarray technology was used to build two sets of tissue array (with versus without PNI) from 50 prostate cancers (PCa). The slides were stained immunohistochemically, and the results were evaluated...


Source: Biotech Week (2003-07-30)

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