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Ben Gurion University of Negev
Microspheres containing growth factor improve alginate scaffold vascularization
July 30th, 2003
Microspheres containing growth factor improve alginate scaffold vascularization. "Site-specific delivery of angiogenic growth factors from tissue-engineered devices should provide an efficient means of stimulating localized vessel recruitment to the cell transplants and would ensure cell survival and function. In the present article, we describe the construction of a novel porous alginate scaffold that incorporates tiny poly (lactic-co-glycolic acid) microspheres capable of controlling the release of angiogenic factors, such as basic fibroblast growth factor (bFGF). The microspheres are an integral part of the solid alginate matrix, and their incorporation does not...
Source: Biotech Week (2003-07-30)
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