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Case Western Reserve University



New gene discovered



July 30th, 2003

Researchers at Case Western Reserve University and University Hospitals of Cleveland report finding a new gene that is switched off early in the development of colon cancer.

The gene, called SLC5A8, is inactivated in 60% of human colon cancers, according to their paper in the July 8, 2003 issue of the Proceedings of the National Academy of Sciences USA.

"The normal version of the gene suppresses the growth of colon cancer tumors, both in the test tube and when grown in mice," said senior author of the paper, Sanford Markowitz, MD, a professor in the Ireland Cancer Center and a Howard Hughes investigator at CWRU and UHC. "However, in our study,...


Source: Biotech Week (2003-07-30)

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