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Biotech Week

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Neurocrine Biosciences, Inc.



Positive phase I trial reported with orally active GnRH receptor antagonist



July 30th, 2003

Neurocrine Biosciences, Inc., (NBIX) announced positive results from the company's phase I clinical trial with its proprietary, orally active small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of multiple dosing of NBI-42902 in healthy premenopausal women.

Results demonstrated that NBI-42902 was safe and well-tolerated.

Eighteen healthy premenopausal women participated in this randomized, double-blind, placebo-controlled, parallel-group, multiple-dose regimen study. The subjects were assigned to three groups of six with each subject receiving daily doses of...


Source: Biotech Week (2003-07-30)

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