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Aarhus University of Hospital
PAI-1 production higher in adipose tissue from obese women than in lean women
July 30th, 2003
The production of plasminogen activator inhibitor-1 (PAI-1) was significantly higher in incubated adipose tissue from obese women than in tissue from nonobese women. According to published research from Denmark, "Human adipose tissue can produce plasminogen activator inhibitor-1 (PAI-1). It has been suggested that high levels of PAI-1 are of importance in enhanced cardiovascular disease observed among obese subjects, especially abdominally obese individuals. In the present study, we investigated the level of mRNA and production of PAI-1 in adipose tissue from two adipose tissue depots (omental vs subcutaneous)." "Adipose tissue from both depots was...
Source: Biotech Week (2003-07-30)
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