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304th Hospital, Beijing
S. aureus-induced biopterin production can trigger septic shock in burn patients
September 10th, 2003
Staphylococcal-induced biopterin production can trigger septic shock in burn patients. "It has been demonstrated that biopterin, an essential cofactor of nitric oxide synthase (NOS), plays an important role in the pathogenesis of endotoxin-induced shock, yet its biological significance in gram-positive sepsis remains unclear," researchers in China explained. In their study, H.Y. Li and coauthors at the 304th Hospital in Beijing "adopted a rat model of postburn Staphylococcus aureus sepsis to investigate the potential role of biopterin in the pathogenesis of gram-positive sepsis." "Wistar rats were inflicted with a 20% total...
Source: Biotech Week (2003-09-10)
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