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Biotech Week

Susan Hasty, Publisher
Table of Contents . . . January 14th, 2004
Non-Subscriber - Summaries Only
Related Areas: Other Issues in Biotech Week | Other Publications

Nippon Boehringer Ingelheim Co. - The angiogenic phenotypes of MT-8 and MT-9 murine tumors are different

Abbott Laboratories - Point-of-care diagnostics company acquired by pharmaceutical firm

CalbaTech, Inc. - Molecula receives license to key RNAi patent

California Dept. of Health Services - Hepatitis C and Schistosoma mansoni coinfections cause T-cell depletion

Canadian Blood Services, Toronto - VIP/NTM peptide mimetics show promise for HIV treatment

Cancer Research UK - MSI-low is a real phenomenon that varies in frequency among cancer types

Cancer Research UK - Rare genetic condition sheds light on body's cancer defenses

Cardinal Health - Program designed to help hospitals, physicians slow spread of flu, SARS

CardioTech International, Inc. - Medical device company announces conversion of warrants

Carnegie Mellon University - Individuals have consistent physiological responses to stressors; immune changes

Carrington Laboratories, Inc. - Shareholder rights agreement amended by biotech company

Case Western Reserve University - Moxonidine effective for metabolic syndrome X treatment in rats

Able Laboratories, Inc. - FDA grants approval for Indomethacin capsules

Catholic University Leuven - Researchers describe stepwise self-organization of molecules

Catholic University of Leuven - VERSANT HIV drug resistance assay effective

Catholic University of Louvain - The cytokine interleukin-1beta is highly expressed in SIDS brains

Cedars-Sinai Medical Center - Specialist suggests pregnant women request vaccine to protect both mom and baby

Celera Genomics - Chimps, humans have striking differences in genes for smell, metabolism, hearing

Cell Therapeutics, Inc. - Oncology company announces approval of shares listing on Nuovo Mercato

Cellegy Pharmaceuticals, Inc. - European regulatory authorities revoke patent related to Cellegesic

Cellular Genomics, Inc. - Alliance signed to study kinase drug targets

Celsion Corporation - Oncology company completes $4M private placement

Cenix BioScience GmbH - Research deal to use genomic high throughput RNAi in human cells

Aceto Corporation - Agreement signed to acquire biopharmaceutical distribution subsidiary of Roche

Center University of Orsay - Huntingtin signaling pathways regulate toxicity in Huntington disease

Center for Corrective Surgery - Polyester implant offers promising new outpatient treatment for snoring

Centers for Disease Control & Prevention - Bat lyssaviruses from Central Asia categorized

Centers for Disease Control & Prevention - CDC releases new guidelines for hygiene in dental care settings

Centers for Disease Control & Prevention - CDC: Flu activity widespread in 45 states

Centers for Disease Control & Prevention - Cytokines act as mediators for or effectors against rotavirus disease

Centers for Disease Control & Prevention - Health departments should adopt new notification policies for gay men

Centers for Disease Control & Prevention - Herpesvirus 8 and Epstein-Barr virus seropositivity among children compared

Centers for Disease Control & Prevention - Immunohistochemical assay for babesiosis in tissue samples developed

Centers for Disease Control & Prevention - Increase in rodent-transmitted disease seen in Hawaii

Active Biotech AB - Positive results confirmed for tumor targeted superantigens cancer product

Centers for Disease Control & Prevention - Intestinal intussusception associated with adenovirus in Mexican children

Centers for Disease Control & Prevention - Invalid vaccine doses would cost millions to fix

Centers for Disease Control & Prevention - Opsonophagocytosis assay effective for Streptococcus pneumoniae antibodies

Centers for Disease Control & Prevention - Vaccine shortages affect child immunization programs

Centers for Disease Control and Prevention - Cold-adapted influenza A H9N2 reassortant is influenza vaccine candidate

Central Institute of Epidemiology, Moscow - Vaccine reduces meningococcal risk in patients with immune deficiency

Centre de Recherches du Service de Sante des Armee - Humans, rats can be tested for plague using the same, rapid serodiagnostic kit

Cepheid - Micro-electro-mechanical systems patent granted on multi-target chip technology

ChemBridge Research Laboratories - Project milestone achieved in alliance with Tanabe

Chemotrade, GmbH - Isonics wins key brachytherapy order

Acusphere, Inc. - Pivotal trials of AI-700 phase III clinical program initiated

Chiba Cardiovascular Center - Pregnant women with repaired CHD have high arrhythmia risk

Chiba University - Amiodarone inhibits only sarcolemmal K-ATP channels in ventricular cells

Chiba University - Endoluminal perspective volume rendering of coronary arteries aids diagnosis

Children's Hospital of Philadelphia - Targeting of chemokine receptors may help stop allograft rejection

Children's Hospital, Westmead - Changes in the noradrenergic system underlie anorexia nervosa risk

Chindex International, Inc. - Supply agreement signed with Chinese hospitals for ultrasound systems

Chinese Academy of Sciences - Liver cells that encode for HCRP1 avoid hepatocellular carcinoma

Chinese Academy of Sciences - Poly(allylamine hydrochloride) disrupts Tat-TAR RNA interaction

Chinese University of Hong Kong - Thrombospondin-1 causes leukemia cells to self-destruct

Chiron Corp. - Experts: Antiquated flu vaccine system needs updating

Advanced Cell Technology - Boston researchers create human clone embryo, magazine reports

Chiron Corporation - Nonexclusive HCV license granted to Boehringer Ingelheim

Cidra Corporation - New business venture formed to commercialize microparticle technology

Ciphergen Biosystems, Inc. - Services deal signed with GE Medical Systems for ProteinChip systems China

College of New Jersey - Coping strategies help healthy women face breast, ovarian cancer risk

Colorado Wound Care - Diabetic patients believe protective footwear lack value

Columbia University - Genetics of food intake and body composition reviewed

Columbia University - Overweight and obesity status are linked to lower life expectancy

Columbia University College of Physicians & Surgeo - Interleukin-24 gene therapy shows promise in the fight against prostate cancer

ComGenex - New genomics screening platform technology developed

CorSolutions, Inc. - CorSolutions provides programs to airline employees to reduce healthcare costs

Advion BioSciences, Inc. - $9M service contract signed for bioanalytical services

Cornell University - Influenza virus needs ubiquitin-vacuolar protein sorting, low pH for viral entry

Coronado Industries, Inc. - Third European marketing agreement signed for glaucoma treatment devices

Corus Pharma - Second phase II study initiated to evaluate Corus 1030

Covalent Group, Inc. - Cardiovascular safety study, other contracts total $8.1M

CryoCor, Inc. - U.S. pivotal trial begins for cardiac cryoblation system

CryoLife, Inc. - Company licenses novel technology for microorganism inactivation

CuraGen Corporation - Novel method for prioritizing genes for drug development published

Cutting Edge Information - Frequent sales force realignments drag down long-term effectiveness

Cutting Edge Information - Launching blockbuster drugs: Marketing budgets push drugs to success

Cutting Edge Information - Market research's role expands, aids pharmaceutical launches

Advocate Christ Medical Center - B-type natriuretic peptide also elevated during pulmonary embolism

Cutting Edge Information - Report shows 85% of prescriptions never get refilled

Cynosure, Inc. - Pulsed dye laser receives clearance for acne treatment

Cyto Pulse Sciences, Inc. - Medarex announces research and license agreement with Maryland company

CytoGenix, Inc. - Agreement signed for preclinical testing of gene-silencing antibacterial agent

Cytokinetics, Inc. - Collaboration signed with AstraZeneca focused on predictive toxicity

Cytomyx Holdings PLC - Clinomics Biosciences in agreement to be acquired

Cytopia - New alliance to focus on cardiovascular disorders

Cytyc Corporation - 20th ThinPrep imaging system shipped to Pennsylvania hospital

Dana-Farber Cancer Institute - Posttransplant survival rates for multiple myeloma patients higher after auto-SCT

Danish Cancer Society - Fish intake is positively associated with breast cancer incidence rate

Aerogen, Inc. - Pharmaceutical company discusses aerosol delivery at AARC meeting

Decision Resources, Inc. - Report: G protein-coupled receptors have significant potential

Dendreon Corporation - Recently acquired San Diego operations closed by oncology firm

Depomed, Inc. - Pharmaceutical company to begin trading on NASDAQ national market

Design Continuum, Inc. - New instruments delivered to genomics company

Dharmacon, Inc. - siSTABLE siRNA launched with increased stability, extended silencing

Diabetex - Disease management firm changes name to XLHealth

DiagnoCure, Inc. - Diagnostics company acquires assets of imaging developer

Diagnostic Products Corporation - Immulite, Immulite 2000 PSA, third-generation PSA assays get CE mark approval

Digene Corporation - Application filed with FDA for approval of chlamydia test

Diversa Corporation - Foreign rights expanded for product discovery from biodiversity

Aetna - Study examines impact of clinical guideline messaging at point of care

Dor BioPharma, Inc. - Davenport named VP, business development at drug delivery firm

Duke University - Allograft rejection possible with antibody mediation by two different mechanisms

Duke University - Cancer survives via signals from nearby blood vessels long before new vessels are grown

Duke University - Having appendix removed by laparoscopy means faster recovery

Duke University - Race affects older Americans' likelihood of getting flu shot

Dyax Corp. - Orphan drug designation granted for DX-890

Eclipse Diagnostics, Inc. - Large Scale Biology announces breakthrough diagnostic technology

Eindhoven University of Technology - Mathematical model developed for arterial wall collagen fiber remodeling

Emory University - Long-term B cell memory found in humans after smallpox vaccination

Endocare, Inc. - Davenport named CEO at medical device company

U.S. Food & Drug Administration - FDA plans to prohibit sales of diet supplements containing ephedra

Afferent Corporation - Device company's neurotechnology improves foot sensation in diabetics

Enzo Biochem, Inc. - Gene identification company reports 73.7% gross profit margin

Epix Medical, Inc. - New drug application submitted for approval of MR angiography indication

Erasmus Medical Center - Drug-coated stents effective in "real world" patients

Erasmus Medical Center, Rotterdam - Gene linked to type 2 diabetes in population from the Netherlands

Ethicon, Inc. - FDA issues alert on counterfeit polypropylene mesh used in surgery

European Inst. of Telesurgery - Surgical treatment may cure type 2 diabetes

European Space Agency - Solving the Ebola enigma: Satellites will provide clues

European Synchrotron Radiation Facility - 3-D synchrotron radiation micro computed tomography reveals bone status

Exelixis, Inc. - Investigational new drug application filed for XL119

Expression Analysis - Genomic capabilities of microarray company bolstered through alliance

Aichi Gakuin University - Oral cavity is a reservoir of HPVs in childhood

Family Health International - Nonlatex condoms provide a viable alternative to latex condoms for some men

FibroGen, Inc. - Company initiates open-label, phase I clinical trial of FG-3019

FibroGen, Inc. - Medarex announces commencement of phase I clinical trial

Forest Laboratories, Inc. - Lexapro receives FDA approval for generalized anxiety disorder

Formatech, Inc. - Clinical supply contract manufacturer gets E.U. GMP certification

Fred Hutchinson Cancer Research Center - Allo-SCT effective for myelofibrosis patients

Fred Hutchinson Cancer Research Center - B lymphocyte-specific c-Myc expression sparks early events in lymphomagenesis

Fred Hutchinson Cancer Research Center - Histone sumoylation associated with transcriptional repression

Fred Hutchinson Cancer Research Center - Protein complexes change red blood cell differentiation

Frost & Sullivan - Report: Hospitals remain cautious about hiring third-party IT services

Akers Biosciences, Inc. - Biotech company announces cancellation of shares

Fudan University - Alpha-actinin may be essential for hepatitis C virus replication

Fukui Medical University - Sendai virus C protein prevents gamma-activated factor from binding

Fukushima Medical Univ. - Maternal serum reveals the presence of placental steroid sulfatase deficiency

GP Strategies - Valera submits NDA for Vantas, an LHRH implant for treating prostate cancer

GTC Biotherapeutics, Inc. - Enrollment complete in European efficacy study for rhATIII

Gen-Probe, Inc. - Testing products company announces 2004 financial guidance

GeneGo - Genomics company names Charles R. Cantor, PhD, to scientific advisory board

Genentech, Inc. - Trial yields positive results for Rituxan plus CVP chemotherapy

Genetronics Biomedical Corp. - Electroporation company names Simon Benito to board of directors

Genmab, A/S - Company files IND for HuMax-CD20 to treat NHL

Al Zytoona University - The prevalence of osteoporosis is high among Jordanian women

Genta, Inc. - Genasense can enhance the activity of Rituxan in NHL

Genta, Inc. - Peter T. Tattle named to board of directors

Georgetown Univ. Hospital - IgA in blood products causes anaphylaxis following transfusion in those with anti-IgA

German Cancer Research Center - Neuroblastoma-derived sulfhydryl oxidase reverses resistance to apoptosis

German Cancer Research Center - Soluble factors role in glioma invasion may lead to new therapies

Geron Corp. - Studies show stability, biological uniformity of different hESC lines

Ghana Health Service - Filariasis prevention programs are adequate for excluding pregnant women

Gifu University - Handheld gene guns effect gene transfer into the beating heart

Given Imaging, Ltd. - Company reports expanded reimbursement coverage for capsule endoscopy

GlaxoSmithKline - Benign prostatic hyperplasia trial to examine dutasteride in combination with alpha-blocker

Alexion Pharmaceuticals, Inc. - Alliance to develop human c-MPL agonist antibody to treat thrombocytopenia

GlobeImmune, Inc. - Alex Franzusoff, PhD, named VP of research

Gothenburg University - Cholera toxin protects against Clostridium difficile toxin A

Great Ormond St. Hospital for Children, London - One form of congenital neutropenia involves neutrophil elastase mutation

Greystone Associates - Study: Noninvasive technologies poised for dramatic growth

Guava Technologies, Inc. - Biomedical company completes $27 million in private equity financing

Hamamatsu University - L-asparaginase treatment may be effective for certain subtypes of AML

Harris Interactive - Survey says reduced leisure time activities may contribute to obesity

Harvard Medical School - Researchers develop approaches to stop anthrax toxin action

Harvard University - African Americans are more dissatisfied than whites with healthcare system

Harvard University - Could observer bias prevent CHD diagnosis in HT users?

Alkermes, Inc. - New treatment for schizophrenia may further relieve symptoms of stable patients

Harvard University - Eating more fruits and vegetables moderately lowers lung cancer risk

Harvard University - HHV-7's U21 transports MHC-I molecules to lysosomes via the ER-lumenal domain

Harvard University - Soy and bioactive components in tea combine to inhibit malignant progression

Harvard University - T-cell costimulatory molecules ultimately assign allograft rejection, tolerance

Harvard University - Upregulation of insulin receptor substrate-2 prevents diabetes

Healthpoint, Ltd. - Gillette veteran Mary Beth Dudley becomes senior HR director

HearUSA, Inc. - Hearing care company completes $7.5 million financing

Hebrew University of Jerusalem - The combination of high serum albumin, fibrinogen, Ig may pose a thrombotic risk

HemoSense, Inc. - Deal signed for INRatio capillary test strips

Henry Ford Hospital, Detroit - Molecular effects of passive mechanical containment characterized

Allicin International - Garlic compound effective against killer MRSA "superbugs"

Hiroshima University - Helicobacter pylori influences angiogenesis and gastric cancer invasion

Hiroshima University - Promoter methylation of cyclin D2 gene may be involved in gastric carcinoma

Hiroshima University - p16 Gene transfer causes abnormal nucleation in radiation-treated cancer cells

Hokkaido University - H. pylori CagA inhibits B cell p53-induced apoptosis; triggers MALT lymphoma

Hokkaido University - Action needed to prevent alveolar echinococcosis epidemic in Japan

Hokkaido University - Spectratype analysis of TCR-VB repetoire may aid GVHD diagnosis

Hopital Necker Enfants Malades, Paris - Infant immune system finishes developing in the first year of life ex utero

Hopital Necker Enfants Malades, Paris - Testing for newborn immunodeficiency is difficult; lymphocyte, Ig levels are low

Hopital Notre Dame de Bon Secours, Paris - Estrogen counteracts urinary tract infections in postmenopausal women

Hospital Carlos III, Madrid - Hepatitis B treatment for HIV patients reviewed

Almased USA - Nutrient selected for study of gastric bypass surgery patients

Hospital Corp. of America - HCA appoints Marilyn Tavenner as group president for outpatient services

Hospital Lariboisiere, Paris - Sensitivity, specificity higher for conventional smears than for ThinPrep

Hospital Miguel Servet - Irinotecan is effective second-line therapy for 5-FU resistant colorectal cancer

Hospital Ramon y Cajal, Madrid - Nelfinavir-based HAART more durable than indinavir-based treatment

Huddinge University Hospital - Mesenchymal stem cells have useful immunomodulatory effects

Hungarian Academy of Sciences - Increased nitric oxide is early sign of premature aging in diabetes

Huntsman Cancer Institute - Population database may aid cancer research

ISTA Pharmaceuticals, Inc. - Company achieves phase III patient enrollment goal for Xibrom

Idenix Pharmaceuticals, Inc. - Pharmaceutical company files registration statement for proposed IPO

Immtech International, Inc. - Dr. Lawrence Potempa named chief scientific officer

Altana AG - Daxas to be submitted for European approval in February 2004

Immucor, Inc. - Reagent company announces new bank credit facility

Immunicon Corp. - FDA 510(k) clearance granted for the CellTracks Analyzer for HIV/AIDS

Immunomedics, Inc. - Presentations address humanized antibodies targeting the CD20 and CD74 antigens

Imperial College of Science, Technol. & Medicine - Perlecan appears to regulate some aspects of tumor angiogenesis

Implant Sciences - Alternative treatment options available for prostate cancer patients

Inamed Corp. - FDA dismisses two petitions seeking to delay application review

Incara Pharmaceuticals Corp. - Drug discovery company announces 2003 net loss of $3,925,000

Incyte Corp. - Patricia A. Schreck becomes general counsel

Indevus Pharmaceuticals, Inc. - Company's FY2003 highlighted by preparation for launch of trospium in 2004

Inex Pharmaceuticals Corp. - Phase I clinical trial for encapsulated anticancer drug delayed until third quarter 2004

Altus Biologics, Inc. - Milestone earned for development of malabsorption treatment

Ingenium Pharmaceuticals, AG - INGENOtyping agreement inked with Max-Planck Institute

Insert Therapeutics, Inc. - Polymeric particles containing transferrin facilitate gene transfer

Insmed, Inc. - FDA grants orphan drug designation for rhIGF-I/rhIGFBP-3, SomatoKine

Inst. Polish Mothers Memorial Hospital - Apoptosis of peripheral blood cells in breast, ovarian patients examined

Inst. of Cancer Prevention, Valhalla - Oral cytology differs between smokers and nonsmokers

Inst. of Hygiene and Tropical Medicine, Lisbon - P. jiroveci DHPS mutations not linked to sulfa drugs in Portugese patients

Inst. of Microbiology & Immunology, Ljubljana - Molecular epidemiology of TB in Slovenia clarified

Institute Gustave Roussy - A real-time PCR assay screens for p53 recombinant adenovirus in patient samples

Institute Gustave Roussy - IP hyperthermic chemo techniques must be draconian in order to be effective

Institute J Paoli I Calmettes - LIGHT, along with CD40L, allows activation of DC, IL-12 by memory T helper cells

Crucell Holland BV - Adenovirus antibodies quantified by luciferase transgene detection

Amer. Soc. For Aesthetic Plastic Surgery - Cosmetic plastic surgery predictions made for 2004

Instituto Grifols - FDA license granted for intravenous immunoglobulin

Instituto de Salud Carlos III - Novel trypanosomatids reported in HIV patients

InterMune, Inc. - Interim findings reported on Infergen plus Actimmune combination therapy

Interleukin Genetics, Inc. - Genomics company announces management changes

International Epidemiology Inst., Rockville - Cancer incidence seen near former nuclear materials facilities in Pennsylvania

Intranasal Technology, Inc. - Company announces newly patented lorazepam nasal delivery system

Introgen Therapeutics, Inc. - New data highlight activity of INGN 241 drug in non-small cell lung cancer

Invitrogen Corp. - Cheri Walker becomes vice president, corporate development

Invivo Corp. - Intermagnetics agrees to acquire patient monitoring company for $22/share

Inyx, Inc. - Drug delivery company enters U.S. eye care market

American Cancer Society - Black men should be screened for prostate cancer at younger age

Isolagen, Inc. - Applikon collaboration leads to manufacturing system breakthrough

Istituto Auxologico Italiano - Air plethysmography useful for body composition measurement

Istituto Superiore di Sanita - HIV Nef induces DC differentiation through Vav signaling

Jagiellonian University - IL-10 release following intracerebral hemorrhage varies depending on hemisphere

Jichi Medical School - Plasmodium berghei circumsporozoite protein protect against malaria

Johns Hopkins Univ. Hospital - AMACR is essential for optimal growth of prostate cancer cells in vitro

Johns Hopkins University - A pair of discoveries helps unravel complex genetics of IBS

Johns Hopkins University - Loss of keratin 6 proteins reveals filaments act during wound repair

Johns Hopkins University - MeCP2, the mutated transcription factor in Rett syndrome, alters nerve synapses

Johns Hopkins University - Measles virus expressing IL-12 alters immune responses in macaques

American Pharmaceutical Partners - Executive director of medical affairs appointed at pharmaceutical firm

Johns Hopkins University - O-GlcNAc plays role in diabetes, cancer, and neurodegeneration

Johns Hopkins University - Proteomic approach for quantitation of phosphorylation developed

Johns Hopkins University - Sclerosing mesenteritis can be diagnosed, followed up by 3-dimensional CT

Johns Hopkins University Hospital - In situ, invasive lobular breast carcinoma share common methylation patterns

KEM Hospital, Bombay - South Indian Nadar have unique HLA alleles, others shared with South Asians

Kagoshima University - Quinapril and candesartan both influence ANP output

Kantonsspital Olten - Acetabular revision in total hip replacement possible without screws

Karolinska Institute - Enterococcus enriched with surface protein gene show increased adhesion

Karolinska Institute - Antibiotic-resistant bacteria frequently transmitted between ICU patients

Karolinska Institute - Small interfering RNAs staunch genes associated with cancer growth

American Shared Hospital Services - Contract signed for 20th Gamma Knife Center in Tennessee

Khon Kaen University - Optical immunoassay for group B streptococcus works better if infection is heavy

Kinexum, LLC - Generex hires life sciences company to help prepare for piviotal Oralin trial

Kishiwada Tokushukai Hospital - Carotid stenosis and peripheral artery disease common in Japanese CAD patients

Korea Institute of Radiological & Med. Science - Oxidative stress-induced apoptosis mediated by ERK1/2 phosphorylation

Korea Research Inst. of Bioscience & Biotechnology - Chimeric antibodies target hepatitis B virus pre-S2 surface antigen

Kumamoto University - VLDL/chylomicron plays role in amyloid formation

Kuopio University Hospital - Efficacy of SCT against peripheral T-cell lymphoma reviewed

Kuopio University Hospital - IL-1 receptor antagonist polymorphisms are associated with preeclampsia

Kyung Hee University - Embolization may be the optimal way to treat pelvic congestion syndrome

Kyung Hee University, Seoul - Animal model shows Korean herbal medicine promotes chondrocyte, bone growth

American Society for Microbiology - Publication provides guidance for shipping biological agents

Kyushu University - The long-term effects of estrogen replacement can be predicted after a year

La Jolla Pharmaceutical Co. - Company submits new drug application for Riquent

Laboratoire de Dietetique Medicale - Very-low-calorie diet promotes long-term weight loss

Laboratory Corp. - Diagnostic technology company announces stock repurchase program

Lam Pharmaceutical, Corp. - Chinese regulatory authorities accept application for approval of wound therapy

Lark Technologies, Inc. - Genaissance to acquire genomic-services company

Legacy Clinical Research & Technology Center - Subcutaneous infusions of VEGF produce new vessel growth in local implants

Leiden University - Peptide nucleic acid down-regulates microsomal triglyceride transfer protein

Leiden University - Real-time PCR is at least as effective as antigen assay to detect G. lamblia

Lonza Group, Ltd. - Genentech inks Rituxan manufacturing agreement

Amgen - Data suggest Aranesp benefits certain cancer patients with anemia

Lorus Therapeutics, Inc. - Company publishes results of clotrimazole analogue studies

Los Alamos National Laboratory - Novel HIV viremia model may aid evaluation of drug efficacy

Los Angeles County Dept. of Health Services - Baseline values of herpes zoster among children and adolescents determined

Louisiana State University - College licenses metabolic drug to Croatian company

Loyola University - New cellular, molecularly targeted agents bring hope to older AML patients

M.D. Anderson Cancer Center - Capecitabine may result in clinical and radiographic tumor responses

M.D. Anderson Cancer Center - IIp45 antagonizes IGFBP-2 stimulation of glioma cell invasion

M.D. Anderson Cancer Center - PI3-K pathway may be major pathway for trastuzumab-mediated radiosensitization

M.D. Anderson Cancer Center - p27(KIP1) has a novel role in down-regulation of telomerase activity

MDS Pharma Services - Butz named VP of global regulatory affairs at drug discovery firm

Amylin Pharmaceuticals, Inc. - Second approvable letter issued for Symlin

Maastricht University - Stressful life events rarely associated with breast cancer risk

MacroChem Corp. - Trial begins for Opterone, an absorption-enhanced topical cream

Mahidol University - Exercise during pregnancy improves spatial learning in newborn animals

Mahidol University - Hematin-targeting 9-anilinoacridines show promise as antimalarials

Managed Care Interface - Study shows controlled-release paroxetine decreases risk of discontinuation

Manchester Royal Eye Hospital - HSV keratitis can occur in keratoplasty as host reactivation, donor transmission

Masimo - Pulse oximetry technology performs reliably under challenging clinical motion

Massachusetts General Hospital - Gender and familial associations are linked to ADHD and major depression

Massachusetts Inst. of Technology - Novel degradable polymers offer a viable alternative to other DNA vectors

Matritech - Patricia Randall becomes VP and general counsel of cancer diagnostics company

Anadys Pharmaceuticals, Inc. - Data reported from phase IB trial of Isatoribine

Matsumoto Dental University - Osteoprotegerin couples with bone resorption to regulate bone formation

Max Planck Institute - High-resolution solid-state NMR used to study membrane proteins

Max Planck Institute - Molecular chaperones protect parkin from oxidative stress inactivation

Maxygen, Inc. - 5HTIA serotonin receptor agonists suppress P. falciparum growth

Mayne Pharma - NaPro completes sale of worldwide paclitaxel business

Mayo Clinic - A rapid serological assay can identify amyloidogenic transthyretin variants

Mayo Clinic - Gene therapy elicits tissue-specific human sodium iodide symporter expression

Mayo Clinic - Incidence of coronary atherosclerosis in type 2 diabetes increased

Mayo Clinic - MAPK pathway may be a potential therapeutic target in ALL

McDaniel College - Chemical modification of insulin occurs in amyloid fibrils

Ancillary Care Management - Pharmacy benefits firm receives URAC health utilization management accreditation

MedImmune, Inc. - Company to study therapeutic benefit of Vitaxin in prostate cancer, psoriasis

MedMarket Diligence, LLC - Report: Gene therapy moving toward approval and introduction within the decade

MedMira Inc. - Company files additional data with FDA on new Reveal Rapid HIV-1 Antibody Test

Medarex, Inc. - Clinical trials begin of antiangiogenesis antibody, CNTO 95

Medi-Cult, a/s - Company launches commercially available in vitro maturation media

Medical Clinic IV, Tuebingen - Tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells

Medical College of Georgia - Treatment targets migraines, head and neck pain

Medical College of Wisconsin - Auto-SCT feasible in elderly multiple myeloma patients

Medical University of Lodz - A whole genome screen reveals five genes associated with multiple sclerosis

MedicalCV, Inc. - Company reports human implant of its Northrup Universal Annuloplasty System

AntiCancer - New imaging methods visualize important elements of tumor-induced angiogenesis

MedicalCV, Inc. - Medical device manufacturer names VP of new technology development

Medicis - FDA approves dermal filler Restylane

Medicsight, Inc. - Company reports FDA approvals, provides progress report

Medtech Insight - Report forecasts 17% annual growth in peripheral vascular stent market

Medtech Insight - Report forecasts more device-based interventions for prostate disease

Meikai University - Mycobacteria-induced SOCS signaling impairs IFN-gamma macrophage stimulation

Mentor Corp. - WARF licenses botulinum toxin

Merck Research Laboratories - Non-obligate chain-terminating ribonucleoside analogs inhibit HCV replication

Meridian Bioscience, Inc. - Company announces new rapid test for stomach ulcers

Merrimack Pharmaceuticals, Inc. - GTC takes equity position in MM-093 developer

Geron Corp. - Positive results reported for telomerase cancer vaccine clinical trial

Aplicare - Hemispherx expands applications for Alferon through manufacturing agreement

Miami University - Adenovirus requires active proteasomes to promote late gene expression

Microbiology & Immunology Inst., Belgrade - Staphylococcus sciuri group may be an infrequent cause of UTI

Micrologix Biotech, Inc. - Company advances MBI-2401 for bacterial infections

Mie University - Caspase-8 activation is an indispensable process in TRAIL-induced apoptosis

Military & Veterans Health Coordinating Board - Safety profile of anthrax vaccine for U.S. soldiers in Korea determined

Millennium Pharmaceuticals, Inc. - Committee recommends early end to confirmatory phase III Velcade trial

Moscow State University - Local end to polio vaccination provides possible scenario for future

Mountain View Pediatrics, Flagstaff - Vaccinations for the pediatric traveler reviewed

Mt. Sinai School of Medicine, New York - Primary biliary cirrhosis research at Mount Sinai advances due to trust, trials

MultiCell Technologies, Inc. - Stem cell licensing deal signed

Applied DNA Sciences, Inc. - Biotech company brings business development veteran on board

NE Ohio University - Estrogen protects against methamphetamine-induced neurological insult

NPS Pharmaceuticals, Inc. - Company begins clinical trial in migraine, appoints chief medical officer

Nagano Matsushiro General Hospital - Miller-Galante II coated prosthesis has good clinical, radiographic outcomes

Nagoya University - Liposomal delivery offers clinical gene therapy for brain tumors

NanoBio Corporation - U.S. Department of Defense awards $3.2M contract for antimicrobial nanoemulsions

NanoCure Corp. - NanoBio forms company to commercialize drug-delivery and imaging technology

Nara Medical University - All-in-one cardiopulmonary bypass circuit for aortic surgery developed

National Cancer Center, Gyeonggi - BRAF mutations do not seem to be involved in gastric cancer development

National Cancer Center. Tokyo - Hepatocyte nuclear factor-1beta is an ovarian cancer molecular marker

National Center for Infectious Diseases - Beta fibrinogen G-455-A polymorphism is risk factor for Legg-Perthes disease

ArQule, Inc. - Oncology-focused biotech firm files $50M shelf registration statement

National Defense Medical College, Saitama - Activation of Galectin-1 gene in human hepatocellular carcinoma examined

National Defense Medical College, Saitama - Hydrogel embedded with growth factor stimulates vascularization in vivo

National Inst. Health Science, Tokyo - Different laboratories find little variability between ELISAs for egg in food

National Inst. for Infectious Diseases, Tokyo - Stx-liposome conjugates show promise as vaccine candidates

National Public Health Institute, Turku - BACTEC MGIT 960 effective for TB drug resistance testing

National University of Colombia - Plasmodial EBA-140 protein peptides protect blood cells from infection

National Yang Ming University - Amorphous oxide film has high stability, low thrombogenicity

Natl. Highway Traffic Safety Admin. - Data show little change in DUI rates

Natl. Inst. of Engineering & Industrial Tech., Lis - Plasmodial aspartic protease characterized

Natl. Inst. of Health & Medical Research, Paris - HIV Nef induces accumulation of MHC II complexes and MVBs

Arena Pharmaceuticals, Inc. - Preclinical studies completed on obesity compound

Natl. Res. Inst. for Child Health & Development, T - Rodents with inducible suicide genes will advance liver disease drug research

NeoRx Corp. - Survival data for patients in STR phase I/II trial presented

New York City Dept. of Health - Isoniazid effective against latent TB in HIV+ injection drug users

New York Eye Cancer Center - High-frequency ultrasonography plays novel role in eye tumor diagnosis

New York State Dept. of Health - Murine models of human liver cancer exemplify malignant mechanisms

New York University - Modified alpha-GalCer analog has improved antimalarial, anticancer activity

New York University - The immunological synapse acts to increase low, decrease high TCR signaling

Newcastle General Hospital - DJ-1 gene polymorphism not linked to Parkinson disease

Nippon Medical College - Reduced transcription of the RB2/p130 gene in human lung cancer analyzed

Nippon Shinyaku Co., Ltd. - The novel pyrrole derivative NS-8 suppresses voiding reflexes in animals

Array BioPharma - Oncology deal signed for development of orally active MEK inhibitor

NitroMed, Inc. - Alliance formed to study pharmacologic roles of nitric oxide

Noninvasive Monitoring Systems, Inc. - AT101 maker announces major narrowing of first quarter loss compared to 2002

Northwick Park Hospital - Bronchoscopy with gastric washings provides optimal smear-negative pulmonary TB diagnosis

Northwick Park Hospital, Harrow - Quality of life after surgical treatment of head and neck cancers reviewed

Norwegian Radium Hospital - Five-year survival rates for oral cancers have not improved

Novacea, Inc. - Target enrollment reached for phase II/III trial studying DN-101

Novartis - Half a million TB patients to get free drugs under new U.N. health agency accord

Novartis, AG - New data show higher dosing of Gleevec achieves higher response rates

Novo Nordisk A/S - Study shows significant reduction in blood transfusion needed in trauma patients

Novo Nordisk, A/S - Genaissance enters into HAP Technology license agreement

Arthritis Foundation - Top arthritis research advances of 2003 announced

Nucletron B.V. - Companies to collaborate on intensity-modulated radiation therapy

Nutra Pharma Corp. - Acquisition to advance treatment of viral diseases and neurological disorders

OXiGENE, Inc. - Company launches expansion of its R&D program in ophthalmology

Ocular Sciences, Inc. - Howard Liszt appointed to board of directors of contact lens company

Oita University - Neuroprotection due to HSP induction may occur with geranylgeranylacetone

Okayama University - Glutamate neurotoxicity may be blockable by a calcineurin-inhibiting peptide

Okayama University - Occupational class correlates with physical activity, heart disease risk in Japanese men

OraSure Technologies, Inc. - Additional data submitted to FDA for OraQuick HIV-2 claim

OraSure Technologies, Inc. - FDA completes inspection of manufacturing facility for oral diagnostics company

Oregon Health Sciences University - Ginkgo biloba prevents memory deficits in Alzheimer disease animal models

Asahi University, Gifu - Subgingival Treponema glycolipids can inhibit TLR, monocyte activation

Organetix, Inc. - Biotechnology company increases production capacity of liver treatment

Osaka City University - Hepatitis C virus in tissue samples helps identify mixed up patient specimens

Osaka City University - Thrombopoietin regulates early neutrophil differentiation

Osaka University - Interneuronal synapse formation, actin restructuring involves cadherins, nectins

Osaka University - Tea polyphenols inhibit glucan-binding domain of glucosyltransferases

Osped Niguarda Ca Granda - Novel cytokines may simplify the management of neutropenia and anemia

Oxford Health Plans, Inc. - Health plan provider expands coverage to include intranasal flu vaccines

Oxford Innovation - Oxford's global network boosts healthcare in the Third World

PPD, Inc. - Patents acquired for development of genitourinary disorder treatments

PainCare Holdings, Inc. - Pain relief-focused company completes $10 million financing

Association of American Medical Colleges - Group establishes new unit to study physician supply in U.S.

Paladin Laboratories, Inc. - Low temperatures in Canada contribute to morbidity and mortality

PamGene International B.V. - Microarray technology company broadens scientific advisory board

Pan American Health Org. - Standardized blood pressure measurement could improve hypertension care

Pan American Health Org. - Use of vaccine is growing worldwide, but more work remains

Panacea Pharmaceuticals, Inc. - Genomics/proteomics-based therapeutics company to develop cancer diagnostic tests in Japan

Pasteur Institute - Extracellular regulated kinases 1/2 are prion protein signaling targets

Paul Scherrer Institute - HIV TAT basic peptide has low affinity for VEGF receptor 2

PediaMed Pharmaceuticals - PediaMed acquires multisite drug delivery platform offering multiple delivery modes

Pellegrin Hospital - Response to hepatitis C virus therapy can be predicted within 4 weeks

Pennsylvania Health Department - No further cases reported in Pennsylvania outbreak

Asthma & Allergy Fdn. of America - Survey shows allergy treatment more costly due to insurance restrictions

Peregrine Pharmaceuticals - European patent granted for phospholipid vascular targeting agent program

Pfizer - Pharmaceutical distributors face new requirements to reduce counterfeiting

Pfizer, Inc. - Human Genome Sciences announces license agreement

Pfizer, Inc. - Pharmaceutical company to purchase up to $5 billion of common stock

Pharmacopeia, Inc. - Enabling science and technology firm to spin-off discovery business to stockholders

Photogen Technologies, Inc. - Company licenses Imagent in Japan to Kyosei Pharmaceutical Co.

Physicians Committee for Responsible Medicine - Twenty-seven new, life-threatening cardiac events reported by Atkins-type dieters

Prana Biotechnology Limited - Alzheimer disease treatment slows progression of cognitive decline in study

PregnancyStore.com - Parents can listen to their baby's fetal heartbeat at home

Prince Charles Hospital, Brisbane - Cardiovascular effects of growth hormone therapy reviewed

AstraZeneca - Dynamic contrast-enhanced MRI displays how ZD6474 affects prostate tumors

Prince of Wales Hospital - Elevated PSA in prostate cancer cells may indicate tumor metastasis

Princeton University - Human cytomegalovirus coding potential reevaluated

Pro-Pharmaceuticals, Inc. - Drug development company appoints new chief financial officer

ProMetic Life Sciences - Agreement made for development of key cancer treatment component

Proctor & Gamble Pharmaceuticals - Imaging studies show risedronate preserves bone health after menopause

Protometrix, Inc. - New technology to help development of medical and diagnostic antibodies

Proxima Therapeutics, Inc. - Study of partial breast irradiation in patients with DCIS announced

Purpan Hospital, Toulouse - Two stem cell transplants double chances for bone cancer survival

Qiagen N.V. - Novel algorithm licensed for gene silencing applications

Qmed - FDA approves Restylane for soft tissue augmentation

Introgen Therapeutics, Inc. - INGN 241 therapy shows safety and clinical activity in phase I clinical trial

Atrium - Plan expands coverage to nasal flu vaccine

Quark Biotech, Inc. - Mouse strain lacking cholesterol develops with little effect

Queen Elizabeth II Health Sciences Centre - Renal abnormalities common in patients who die after SCT

Queens University - Hypogonadism correction offers men several mental and physical benefits

RTI International, North Carolina - Inhaled tertiary amyl methyl ether vapor affects reproduction in male rodents

Radiancy, Inc. - FDA grants clearance for light unit assembly acne vulgaris treatment

Roche - 48-Week data submitted to FDA for full approval of HIV fusion inhibitor

Roche - FDA approves labeling for use of Xenical in adolescent patients

Roche - Losing weight with Xenical cuts threat of developing type 2 diabetes

Roche Diagnostics - Genetic disorder tests receive FDA clearance and CE Mark

Roche Diagnostics Corp. - New 3-year hospital blood glucose contract awarded

Atrix Laboratories, Inc. - Drug delivery company adopts Rule 10B5-1 policy

Rockefeller University - Cholesterol-regulated SREBP and LXR target genes identified in mice

Rowett Research Inst. - CSF treatments, laser light therapy may aid restitution and repair of mucositis

Royal Free & Univ. College Medical School - Adeno-associated viruses suitable for therapy must be devoid of contamination

Royal Free Univ. College Medical School - Treatment of amyloidosis may involve targeting of proteins or disease process

Royal Prince Alfred Hospital - Bone invasion alone doesn't predict survival rates for oral cancer patients

Rubicon Medical Corp. - Medical device manufacturer names new VP of regulatory and clinical affairs

Rutgers State University - Enzyme induction, dietary chemicals may be approaches to cancer chemoprevention

SA Water Corporation - Methods for counting water-borne bacteria compared

Saegis Pharmaceuticals, Inc. - CNS-focused biopharmaceutical company announces new vice president

San Bortolo Hospital - Growth hormone prevents skeletal muscle atrophy in rats

Autonomous University of Madrid - In rheumatoid synovitis, early fibrin deposition should be targeted for therapy

Sangamo BioSciences, Inc. - Oncolytic vector technology licensed for development of cancer therapy

Sanquin Blood Supply Fdn. - Genmab joins with Dutch nonprofit to improve hemophilia treatment

Schering AG - New drug application submitted to FDA for lower-dose Yasmin

Schering, AG - MS-325 for magnetic resonance angiography submitted for approval in the U.S.

Schering-Plough Corp. - Study: Noxafil demonstrates significantly better outcome

ScienceBased Health - New study finds HydroEye beneficial to LASIK patients

Scripps Research Institute - Cocaine-binding scFv antibody can be made in E. coli, purified, freeze-dried

Scripps Research Institute - Regenerative chemical turns muscle cells into stem cells

Seattle Biomedical Research Institute - Gates Foundation gives $10 million grant to develop pregnancy malaria vaccine

Seattle Genetics, Inc. - Antibody-drug conjugate collaboration designates additional antigen targets

Avanir Pharmaceuticals - Pharmaceutical firm reports lower revenues, provides clinical update

Second Military Medical University, Shanghai - Effects of clonidine mediated by NMDA receptors in RVLM

Seitoku University - Numerical methods are adequate for estimating dietary iron requirements

SemBioSys Genetics Inc. - Development agreement executed with Martek Biosciences

Sequenom, Inc. - Genetics company announces osteoporosis collaboration

Shire Pharmaceuticals Group plc - Agrylin licensed in Japan for treatment of thrombocythemia

Showa University - Novel method facilitates small dense LDL quantification

Silesian School of Medicine - Phalangeal quantitative ultrasound delineates women with nontraumatic fractures

Skinvisible, Inc. - Hand sanitizer provides greater than 99% kill against influenza A in studies

SkyePharma, PLC - Study: Patients treated with Paxil CR are less likely to discontinue therapy

Solove Research Institute - Researchers get easy access to leukemia gene information

Aventis - Molecular cytogenetics alliance formed to validate cancer drug targets

SomaLogic, Inc. - Japanese corporations invest $11 million in proteomics company

Sosei Co. Ltd. - Japanese biopharmaceutical company co-promotes prostate cancer treatment

Southern Arizona VA Health Care System Hospital - AT₁ blockade enhances vasorelaxation during heart failure

SpectRx, Inc. - FDA grants second major patent for insulin delivery patch

Spectral Diagnostics Inc. - Companies form joint venture for R&D of infectious diseases diagnostics

Spectrum Pharmaceuticals, Inc. - Abbreviated new drug application filed with FDA for Fluconazole

Sports Orthopedics & Spine, Jackson - Modified Neviaser portal safer due to position

St. Jude Children's Hospital - Pharmacokinetic models are important for childhood cancer drug development

St. Jude Children's Hospital - Usefulness of FISH in morphologically ambiguous gliomas examined

St. Jude Children's Hospital, Memphis - Etoposide treatment triggers chimeric Mll gene fusions in vitro

Aventis - Nautilus Biotech reaches milestone in vaccine collaboration

Stanford University - Expanding public insurance for HIV/AIDS could markedly increase survival rates

Stanford University - Pediatric renal graft loss linked to non-adherence, teenage, mental illness

Stanford University - Relationship between technology availability, healthcare spending analyzed

Stanford University - VEGF is a prerequisite for exercise-induced hippocampal neurogenesis

State Univ. of New York, Albany - Culture, demography, and biology interact to determine genetic trait prevalence

State Univ. of New York, Buffalo - Utilization of virtual reality for endotracheal intubation training evaluated

State University of New York, Buffalo - Epidemiology of severe respiratory syncytial virus infection reviewed

State University of New York, Buffalo - Lung cancer is not associated with lifetime total alcohol consumption

Statens Serum Institute - Greenlandic Inuit have increased incidences of several cancers

Sterion Incorporated - Medical products company reports fiscal 2003 and fourth quarter results

Aventis Pasteur - FDA investigating reports of unlicensed influenza vaccine

Structural GenomiX, Inc. - Biotech companies join to develop treatments for urological cancers

Stryker Corporation - Medical product manufacturer announces production facility expansions

Suntory Pharmaceutical Research - HMGene enters obesity drug agreement

Syneron Medical, Ltd. - FDA approves Polaris WR wrinkle treatment system

Technical University of Lodz - Microwave energy dose affects immunoreactivity of gliadin and wheat flour

Technology Foundation STW - Tumor growth model estimates risk of cancer

Temple University - Dysphagia, hoarseness among risks of anterior cervical diskectomy and fusion

Tetracore, Inc. - First FDA-cleared laboratory test for Bacillus anthracis

Texas Tech University - Researchers find low levels of perchlorate in evaporated milk samples

Thames Water Utility - Immunomagnetic-based method detects Cryptosporidium, Giardia oocysts

Avitar, Inc. - Oral fluid diagnostics company sells laboratory subsidiary

The Boston Consulting Group - Patients skip doses of prescribed drugs on purpose

The Speedel Group - Cardiovascular/metabolic disease-focused company opens representative office in Japan

Tiax - U.S. patent issued for multilayered dressing

Tohoku University, Japan - II beta-hydroxysteroid dehydrogenase type 2 is expressed in ARDS patient lungs

Tokyo Medical & Dental University - Prefabrication of bone flap induced by bone morphogenetic protein 2

Tokyo Medical & Dental University - Regions of Epstein-Barr virus protein activate NF-kappa B

Tokyo Metropolitan Neurology Hospital - Neurons in Duchenne, myotonic dystrophy have excess non-cholinergic synapses

Tottori University - Intraoperative GH measurement helps boost safety of secondary transnasal surgery

Transplant Clinic, Halifax - Acute kidney rejection is lower with basiliximab, independent of cyclosporine

Treviglio Hospital - Effort needed to develop new prophylaxis, treatment for venous thromboembolism

Axcan Pharma, Inc. - CPMP positive opinion issued in Europe for Photobarr

Trigen, Ltd. - Data presented on neutralizing agent for anticoagulant direct thrombin inhibitors

Trimedyne, Inc. - Lumenis litigation settled

Tripler Army Medical Center - Treatment of lower extremity injuries due to land mines examined

Tufts University - Linezolid does not raise thrombocytopenia risk in nosocomial pneumonia patients

U.S. Dept. of Health & Human Services - National reports on quality, disparities in healthcare services use released

U.S. Food & Drug Administration - Drug carcinogenicity determined using structural similarity and E-state index

U.S. Food & Drug Administration - Liquid chromatography method for impurities in methoxsalen developed

U.S. Food & Drug Administration - Rapid identification method for E. coli O157:H7 using real-time PCR developed

U.S. Food & Drug Administration - U.S. officials say it's too costly to legalize drug imports

U.S. Food & Drug Administration - galE gene in campylobacters linked to Guillain-Barre syndrome

Axonyx, Inc. - Scope of Phenserine trial; sub-study to include brain scans

U.S. National Cancer Institute - Occupational cancer among women: Where have we been and where are we going?

U.S. National Cancer Institute - Skin capillary endothelium SDF-1 plays key role in Kaposi sarcoma pathogenesis

U.S. National Cancer Institute - Studies evaluating fenretinide are underway

U.S. National Institutes of Health - Anti-HIV alkaloids isolated from Monanchora sponge

U.S. National Institutes of Health - Common variable immunodeficiency may be treatable with B lymphocyte stimulator

U.S. National Institutes of Health - Large animal models have advantages in drug, tolerance transplantation research

U.S. National Institutes of Health - Multiple gene and clade HIV-1 DNA vaccines broaden immune response

U.S. National Institutes of Health - NHGRI launches social and behavioral research branch

U.S. National Institutes of Health - NK cell activating receptor NKp46 is similar to other leukocyte receptors

U.S. National Institutes of Health - Strand-specific RNA synthesis defects found in mutated poliovirus

510-262-8757 - $15M milestone payment awarded for developments in anticancer compound

Azienda Osped San Camillo Forlanini - Intragastric balloon effective for weight loss in obese patients

U.S. National Institutes of Health - Teen drug abuse declines across wide front

U.S. Natl. Inst. of Child Health & Human Developme - U.S. NIH alerts parents to winter SIDS risk

U.S. Natl. Inst. of Environmental Health Sciences - Some CpG G:C-A:T transitions may be caused by smoking

U.S. Natl. Inst. of Standards & Technology - Test method provides biocompatibility "barometer"

U.S. Naval Medical Center - Obesity linked to aggressive prostate cancer

U.S. Naval Medical Research Ctr. Detachment, Lima - Primaquine effective for prevention of malaria in travelers

ULB Erasme - Minocycline activates the tetracycline-responsive promoter in treated cells

Ullevaal University Hospital - HAART has limited effect on hypertension risk

Umea University - Bone inductive substances improve new bone formation where estrogen is absent

Unipath, Ltd. - Inverness to supply Pfizer with a digital version of its e.p.t pregnancy test

Baptist Health System, Birmingham - Alabama system names new president and CEO

United Nations - Campaign gathers pace on both sides of front line

United Nations - Ethiopia minister blasts doctor's group over treatment

United Nations - Thousands threatened by epidemic in southern Africa

United Nations - U.S. labor secretary launches HIV/AIDS initiative in Ghana

Univ of Alabama, Birmingham - Hepatitis C virus infection may encourage the formation of diabetic amyotrophy

Univ. Autonoma of Nuevo Leon - Peyote cactus extract can activate NO, increase cytokines, kill tumor cells

Univ. Hospitals Gasthuisberg, Leuven - Chorioamniotic membrane separations follow invasive intrauterine procedures

Univ. of A Avogadro Piemonte Orientale - Recent insights on the mechanisms of liver preconditioning evaluated

Univ. of Alabama, Birmingham - Oncolytic viruses used as vectors for treatment of malignant gliomas

Univ. of British Columbia - Neutralizing antibodies to IFN beta-1b therapy for relapsing-remitting MS may affect outcome

Bar Ilan University, Ramat Gan - Apoptotic cell shrinkage can be tracked in individual lymphocytes by staining

Univ. of California, Berkeley - Single gene plays key role in neural tube defects

Univ. of California, Davis - Wild-type p53 in prostate tumor cells may reduce the effectiveness of radiation

Univ. of California, Irvine - Down syndrome study reveals possible method for detecting initial stages of AD

Univ. of California, Los Angeles - Drug resistance remains a major clinical challenge in multiple myeloma

Univ. of California, Los Angeles - Shyness can be deadly

Univ. of California, Riverside - Rapid botulinum toxin type B microsensor developed

Univ. of California, San Diego - Microarrays reveal macrophage gene expression after TB infection

Univ. of California, San Diego - Short T2 components may show high signals in many tissues

Univ. of California, San Francisco - Mitosis by activated protein kinase B involves polo-like kinase 1

Univ. of California, San Francisco - Synthetic cysteine protease inhibitors have potent antimalarial activity

Barr Laboratories, Inc. - FDA panel votes to allow sale of emergency contraceptive

Univ. of Complutense, Madrid - Bulimia nervosa patients and normal eaters have similar 5-HTT gene mutations

Univ. of Erlangen Nurnberg - Diagnosis of different paraproteinemias requires extensive renal histology

Univ. of Iowa Hospitals & Clinics - Interventions needed to promote adoption of evidence-based acute pain management

Univ. of Medical Science, Poznan - Novel mutation found in patient with Treacher Collins syndrome

Univ. of Nottingham Hospital - Contact lenses can relieve pain, promote healing

Univ. of Rochester Medical Center - Study finds many early-stage breast cancer patients not completing chemotherapy

Univ. of Sacred Heart, Rome - Gemcitabine effective alone or in combination with carboplatin, paclitaxel

Univ. of Southern California - Dermal-epidermal junction type VII collagen produced by fibroblasts

Univ. of Texas Health Science Center - Radiotherapy may be effective alternative, adjunct in treating head, neck cancer

Univ. of Texas Medical Branch - Butyrate can inhibit pancreatic cancer metastasis by inhibiting P4 integrin

Bayer Pharmaceuticals Corp. - FDA grants Cipro additional 6 months marketing exclusivity

Univ. of Texas Medical Branch - DNA base excision repair proteins help fix oxidative DNA damage

Univ. of Texas SW Medical Center - Dallas barbers become blood-pressure specialists for African American men

Univ. of Texas SW Medical Center - LDL receptor-related protein controls blood-brain barrier permeability

Univ. of Texas SW Medical Center - Piccolo proteins pique neurons

Univ. of Texas SW Medical Center - Researchers discover first effective treatment for exercise disorder

Univ. of Western Ontario - Vascular changes prevail in disorders that host chronic neuroinflammation

Universit Paris-Sud - Nerve degeneration in familial amyloid polyneuropathy studied

Universitat Heidelberg - Niemann-Pick disease type C caused by disturbed lipid transport

Universitats Augenklinik Essen - Thyroid-associated ophthalmopathy can be treated by anti-inflammatories, surgery

University Clinic Schleswig - Prostatectomy and radiotherapy present similar quality of life outcomes

Baylor College of Medicine - Bone mineral mass not decreased in overweight and obese children

University Hospital Dusseldorf - Toxin-gene profile heterogeneity found in group A streptococcus

University Hospital Zurich - Overt thyroid disorders must be managed during pregnancy

University Hospital, Bordeaux - Potential genetic links to diabetes and cardiovascular disease discovered

University Hospital, Nottingham - Pharmacological therapy for chronic heart failure reviewed

University Hospital, Orebro - Low incidence of non-Hodgkin lymphoma in Sweden may result from carcinogen bans

University Hospital, Pamplona - Vaginal reconstruction by modified rectus abdominis musculocutaneous flap

University Hospital, Uppsala - Regimen of HiDAC, AMSA and G-CSF provides efficient stem cell mobilization

University Hospital, Vienna - Circulating tuberculostearic acid may aid TB diagnosis

University Kebangsaan Malaysia - Imperforate hymen may have familial origins

University Medical Center, Nijmegen - Donor lymphocyte infusions effective against post-SCT indolent NHL

Baylor College of Medicine - Broadly applicable heat shock protein-mediated tumor vaccine developed

University at Buffalo - Husband's drinking behavior influences social life of newlyweds

University of Aberdeen - Sublingual or vaginal misoprostol combines with mifepristone to abort pregnancy

University of Alabama - Delta-class GST from DDT-resistant An. gambiae characterized

University of Alberta - Late rejection may still be due to antibodies; diagnostics, cures are needed

University of Alberta - TRAIL triggers apoptosis in human malignant glioma cells

University of Arkansas - Scientist finds how cancer triggers bone disease, eyes treatment

University of Auckland - Crystal structure of M. tuberculosis MshB protein characterized

University of Barcelona - Chemoembolization improves survival for many with unresectable liver cancer

University of Bern - Activated gamma delta T cells go to lymph nodes; increase antibody production

University of Bern - Women with hereditary risk for thrombophilia need preconception screening

Beckman Coulter, Inc. - Garrett named president, chief operating officer at biomedical company

University of Birmingham - Birt-Hogg-Dube in activation occurs in some renal cell, colorectal cancers

University of Birmingham - Crystal structure of M. tuberculosis FbpC1 characterized

University of Bonn - Epigenetic silencing of HIC-1 may play role in most medulloblastomas

University of Bradford - Transformation into gamma-lactone augments quassin's antimalarial activity

University of British Columbia - T-plastin shows potential as Sezary cell-specific marker

University of Buenos Aires Paraguay 2155 - Free fatty acids induce cell differentiation in Trypanosoma cruzi

University of Calabria - Human sirtuin 3 gene plays role in longevity

University of California-Los Angeles - 12-Lipoxygenase plays role in experimental diabetic nephropathy

University of Cambridge - Intercellular adhesion molecule-1 gene associated with type 1 diabetes

University of Carabobo - Control measures of Lutzomyia longipalpis s.l. in Venezuela outlined

Best Practices, LLC - Report reveals how companies optimize biomarker research

University of Chicago - Methylnaltrexone inhibits opioid-mediated HIV macrophage infection

University of Cincinnati - Protein kinase C alpha impairs ventricular function during cardiac hypertrophy

University of Colorado - Desflurane general anesthesia alters hepatic venous pressure

University of Colorado - Specific T cells occur in lung, not circulation, in chronic beryllium disease

University of Connecticut - New ex ova models are expected to enhance preclinical research efforts

University of Copenhagen - Body composition measurement may help therapy choice for obesity

University of Copenhagen - Glucagon-like peptide 2 may have clinical use in short-bowel syndrome

University of Cordoba - ApoE gene promoter -219G/T mutation alters postprandial TRL metabolism

University of Edinburgh - Novel homeobox gene identified in embryonic stem cells

University of Edinburgh - TNF-alpha may play an early role in the malignant transformation of liver cells

Bharathiar University - Gymnema montanum leaves possess antidiabetic effect

University of Essen Gesamthsch. - Orthotopic bladder replacement for advanced cancer shows great long-term results

University of Essex - High-intensity exercise such as shoveling snow can be a danger to your heart

University of Florida - Cancer more likely to recur in blacks

University of Florida - Strong families enjoy most support from those who find it difficult

University of Genoa - Human natural killer cells patrol for aberrant HLA-I expression, kill deviants

University of Glasgow - Trypanosoma homologous recombination changes if mismatch repair is impaired

University of Glasgow - Chondrosarcoma of the hand behave differently than other chondrosarcomas

University of Groningen Hospital - Novel hyaluronan-based biomaterials support nerve repair

University of Haifa - Changes in marital relationships among parents of children with cancer examined

University of Heidelberg - Differentiating intraocular inflammation, infection can be done by vitrectomy

AEterna Laboratories, Inc. - Neovastat's clinical development plan updated

BioMer, C.V. - Merck, KgaA, to exit orthopedics joint venture to focus on core businesses

University of Heidelberg - Imiquimod 5% cream effective against viral warts

University of Heidelberg - There are many uses for single, combined therapeutic vitrectomy for uveitis

University of Hong Kong - Nonmyeloablative SCT from kidney donor can resolve PTLD

University of Hong Kong - Proangiogenic cytokine regulates vascular remodeling during chronic hypoxia

University of Hong Kong - Survivin halts gastric cancer tumorigenicity and angiogenesis

University of Hull - Cholesterol paradox: Lower values bad omen for heart failure patients

University of Illinois - Cell's motor is a mountain climber, not an inchworm

University of Illinois - Modified GFP reporter-based assay useful for anti-TB drug screening

University of Innsbruck - Gamma-aminobutyric acid receptor expression increased in epilepsy

University of Ioannina - Isolated intraparotid Kaposi sarcoma possible during effective HIV treatment

BioMicro Systems - New microarray hybridization chamber launched

University of Kiel - Sacral neuromodulation beneficial for patients with neurogenic urinary retention

University of Kuopio - New MRI contrasts discern response to gene therapy in rodent glioma models

University of Laval - LDL peak particle diameter is highly heritable

University of Leipzig - Electronic endocardium mapping reviewed

University of Liverpool - Molecular assay aids identification of An. minimus vectors

University of Liverpool - Oral ulceration may indicate Behcet disease, inflammatory bowel syndrome

University of London - Balance of activator, inhibitor Fc gamma receptors may influence kidney disease

University of London - Complement deposition may soon be blockable; to stop kidney pathology, rejection

University of London Birkbeck College - Crystal structure of truncated human beta B1-crystallin reported

University of Lund Hospital - Cancer cells are characterized by having aberrant chromosomes

BioNumerik Pharmaceuticals, Inc. - Mechanism-based drug discovery firm raises $29M in private placement

University of Madrid - Early antiretroviral treatment is neuroprotective in vertically infected children

University of Malta - Select vitamin D receptor gene changes don't obscure bone mineral indices

University of Manchester - Mammary epithelial cells express the osteopontin mediator Runx2

University of Maryland - Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs

University of Maryland - U.S. officials say interviews for HIV study were fabricated

University of Massachusetts - In CSR, mutation rates and patterns differ greatly, depending on the region

University of Michigan - Doctors more likely to prescribe pricey new drugs despite standards

University of Michigan - Intranasal RANTES/CCL5 chimera plus truncated exotoxin may prevent fungal asthma

University of Michigan - Scientists discover how anthrax creates its deadly spores

University of Michigan - Study: Reduced FDA resources cause of decline in drug approval times

BioPoint Solutions, Inc. - New company launched to help biotech, pharma firms handle data management

University of Milan - Kit elements needed for stem-cell expression identified

University of Milan - Neurons of dorsal motor vagal nucleus show hypoxia-related marker in SIDS brains

University of Milan - TIPS improves cardiac function in hypovolemic patients

University of Milan Bicocca - Effects of aging on cardiovascular system reviewed

University of Minnesota - Arsenic trioxide increases the thermosensitivity of tumors

University of Minnesota - Environmental tobacco smoke significantly affects nonsmokers

University of Munich - A new B*38 allele, B*3809, was found in a Dutch caucasoid B-cell line

University of Munich - Prostate cancer and erectile dysfunction. Which therapy when?

University of Munich - Time spent learning how to treat foreign patients would ultimately reduce costs

University of Murcia - Microangiogenesis facilitates parkinsonism

BioVisioN AG - Peptidomics company names new chief scientific officer

University of Naples Federico II - Consolidation therapy improves sustained response in HCV genotype 1b patients

University of New South Wales - DHEA increases macrophage foam-cell formation

University of Newcastle - Protein A-tagging allows purification of complexes from Candida

University of North Carolina - Study reveals few problems banning smoking at schools

University of Northern Iowa - Morning glory extract has antituberculosis activity

University of Nottingham - Maternal undernutrition doesn't correlate with infant birth weight indices

University of Ouagadougou - Burkina Faso medical plants have antimalarial activity

University of Oxford - Intracellular localization of self-antigen promotes autoreactive B cells

University of Oxford - Recombinant SP-D can improve surfactant replacement therapy in neonatal lungs

University of Oxford - Two-brood P. falciparum replication during quinine treatment suspected

Bioanalytical Systems, Inc. - Contract research organization reports 23% increase in revenue

University of Padua - Sudden-death risk tracked in large, long-running study of young athletes

University of Paris - 3-D ultrasound assesses lung volume in cases of congenital diaphragmatic hernia

University of Paris - Innervation may be early target in type 1 diabetes

University of Pennsylvania - Alloimmunity may be controllable by targeting cell-cycle regulators

University of Pennsylvania - Sociocultural influences may affect genetic testing among African American women

University of Pittsburgh - Allotrap peptide RDP58 inhibits aortic graft arteriosclerosis

University of Pittsburgh - Alveolar macrophage killing of P. carinii depends on Dectin-1 beta-glucan receptor

University of Pittsburgh - Degradation of angiotensin II in kidneys characterized

University of Pittsburgh - Early hormone replacement is fundamental to limiting cognitive decline

University of Pittsburgh - Gadd45a contributes to p53 stabilization in response to DNA damage

Bioject Medical Technologies - Phase I study completed comparing needle-free system to traditional syringe

University of Pittsburgh - Miscommunication and poor medical advice contributes to unplanned pregnancies

University of Pittsburgh - Patients diagnosed with hip fracture are not receiving adequate follow-up

University of Pittsburgh - Researchers study broccoli-derived chemicals to prevent cancer

University of Portsmouth - Short-term meningioma cultures express key matrix metalloproteinases

University of Rochester - Pseudomonas aeruginosa has two quorum sensing systems that could be targeted

University of Rochester - Embolization highly effective, minimally invasive to control bleeding

University of Roma Tor Vergata - Diagnosis of obesity cannot be based on body mass index alone

University of Rostock - Renal biopsy histology does not correlate highly with most clinical syndromes

University of So. Denmark - PPARdelta transactivation occurs in psoriasis; may be linked to pathology

University of South Dakota - Thyroid hormone treatment improves cardiopulmonary function in male SHHF rats

Biomet, Inc. - FDA clears Palacos G antibiotic-loaded bone cement

University of South Florida - Managing older chemo patients involves preventing pharmacologic complications

University of South Florida - Notch signaling necessary but not sufficient for dendritic cell differentiation

University of Southern California - "Paper of the year" recognizes significance of gene variance findings

University of Southern California - Lycopene inhibits the growth of normal human prostate epithelial cells in vitro

University of Szeged - A whole genome screen reveals 33 genes associated with multiple sclerosis

University of Texas - New adenoviral vector technology wins patent; Introgen gets license

University of Tokushima - Overexpression of TSC2 may exert the antitumor effect on oral cancer cells

University of Tokyo - CO poisoning is due to ROS affecting neurons; hypothermia can reduce the damage

University of Tokyo - Hepatitis C virus core protein upregulates TGF-beta₁ transcription

University of Tokyo - Male gender heightens risk of after hematopoetic SCT late-onset hemorrhagic cystitis

Biomira, Inc. - Cancer drug development status reported

University of Tokyo - Microarray analysis should prove useful for identifying tumor markers

University of Toronto - An automatic technique for breast symmetry detection presented

University of Toronto - Genetics research could spawn further creation of targeted, nontoxic therapies

University of Toronto - New understanding of why brain cells die after stroke will lead to new treatments

University of Tsukuba - Dentists must be diligent in recognizing ulcerative lesions, small oral cancers

University of Tubingen - CD8 T cells expanded on calibrated MHC/anti-CD28-coated microspheres

University of Turin - Most in situ breast cancers represent focal lesions derived from single clone

University of Turin - Response to ghrelin administration decreased in human obesity

University of Turku - Finish study finds many physicians skeptical about complementary therapies

University of Ulster - Kinestatin is novel bradykinin B-2 receptor antagonist peptide

Biophan Technologies, Inc. - Nanomagnetic particles used as contrast agent improves detail

University of Uppsala Hospital - Neuropsychological assessment useful as complement to neurological exam

University of Utrecht - Increased systemic temperature seen during regional hyperthermia

University of Vienna - Lipid oxidation products have both pro and anti-inflammatory effects

University of Washington - Antifungals affect gene expression in pathways of Candida albicans

University of Washington - Genetic loci linked to LDL size and TG levels in FHTG identified

University of Wisconsin - Stem cells illuminate early stages of human development

University of Wisconsin - Time profile of L-dopa metabolites in nonhuman primates determined

University of Wisconsin, Madison - Influenza immunization decreases CYP3A4 activity in vivo

University of Witwatersrand - Aflatoxin B-1 and hepatitis B virus synergize to encourage hepatocarcinogenesis

University of Wurzburg - Skin inflammation, cancer therapy may benefit from targeting the lymphocyte path

Abbott Laboratories - A reversible inhibitor of methionine aminopeptidase-2 quells tumor growth

Birmingham Heartlands Hospital - A new line probe assay identifies hepatitis B virus precore variants in sera

University of Zurich - Nuclear factor-kappa B dependent gene expression involves p300, PARP-1

University of the Sacred Heart, Rome - Apolipoprotein E is a nerve recovery and neovascularization intermediary

V Segalen University - Chromosomal imbalances indicate tumor relapse in cutaneous CD30+ T-cell lymphoma

VA Medical Center, Kansas City - 2-Methoxyestradiol has a biphasic effect on new vessel growth

VA Medical Center, Minneapolis - High-sodium diet has blood pressure-independent adverse vascular effects

Vanderbilt University - Antiretroviral treatment increases oxidative stress

Vanderbilt University - Imaging mass spectrometry allows profiling and imaging of proteins

Vanderbilt University - Organic anion-transporting polypeptide plays role in drug disposition

Vanderbilt University - Soluble EphA receptors stop VEGF-dependent tumor angiogenesis

Vanderbilt University - p63 Amplification, overexpression occurs early in developing lung cancer

Bloomberg School of Public Health - Children get better care with developmental specialists on physician team

Vertex Pharmaceuticals Inc. - University and pharmaceutical company form drug discovery collaboration

Vertex Pharmaceuticals Incorporated - Investigational drug, merimepodib, well tolerated in hepatitis C clinical trial

VirRx, Inc. - Oncolytic viral technology licensed to Introgen Therapeutics

Virginia Commonwealth University - Immunosuppressant FTY720 may be phosphorylated by sphingosine kinase type 2

W. Australian Ctr. for Pathology & Medical Researc - PCR assay can aid malaria diagnosis in patients with low parasitemia

Wakayama Medical University - Hormone receptor status and tumor vessels change with endometrial progression

Wake Forest University - Obesity increases risk for thrombotic thrombocytopenic purpura

Walter Reed Army Inst of Research - Leukocyte DNA fragmentation may be diagnostic for low exposure to nerve agent

Washington Homeopathic Products - Some turn to homeopathic remedies to combat flu

Washington University - Cryptococcus neoformans capsule formation can be blocked by RNA interference

Boston Biomedica, Inc. - Diagnostic kit gets FDA approval

Washington University - Hydroxychloroquine effective as GVHD prophylaxis after unrelated transplant

Washington University - Major differences between pediatric, adult meningeal tumors reported

Wayne State University - Positioning of prostate cancer patients during radiotherapy studied

Wayne State University - Scientists provides new insights into basis of diabetic neuropathy

Wayne State University - Sphingolipids may be an alternative to conventional drugs

Weill-Cornell Medical Center - Potassium iodide should be available to people living near nuclear power plants

Welch Foods, Inc. - Concord grape juice improved memory, neuromotor skills in animal study

Wellcome Trust Laboratories, Chichiri - Schistosomiasis does not affect NTS bacteremia outcome in HIV+ Malawian adults

West Virginia University - p38 MAPK mediates negative inotropic effect of gp120 on myocytes

Westmead Hospital, New South Wales - CnLYSO1 is an extracellular lysophospholipase of Cryptococcus neoformans

Boston University - Antibody- and RNA-based HIV testing should be offered to suspected patients

Whitehead Institute - Mad cow mechanism may be integral to storing memory

Wistar Institute - Chemokines and TRANCE act as genetic adjuvants for rabies DNA vaccine

Women's Capital Corp. - Women are not likely to abuse over-the-counter emergency contraception

World Health Organization - HIV has significant influence on leishmaniasis epidemiology

World Health Organization - U.N.: Spread of polio in West Africa threatens global eradication drive

World Health Organization - WHO: Battle against AIDS will founder without boost to basic healthcare

Wyeth - National survey shows coughs keep Americans away at work, home, and play

Wyeth Ayerst Research - Antigen-coating concentration affects presentation of Neisseria epitopes

Wyeth Pharmaceuticals - CDC: Vaccine shortage likely

Yale University - Brain area that regulates emotions is smaller in manic-depressive people

Bradley Pharmaceuticals, Inc. - Pharmaceutical company signs agreement for probiotics development

Yale University - Hormone imbalances contribute to bone loss in lactating mammals

Yale University - Hoxa10 transcription factor mediates endometrial differentiation

Yale University - Natural killer T cells are responsible for skin allergies

Yale University - Protein tyrosine phosphatases in nervous system reviewed

Yale University - Well-tolerated mobilization regimen effective for multiple myeloma patients

York Nutritional Laboratories - Home metabolic analysis kit now available

Zhejiang University - Conotoxin MVIIA and thioredoxin fusion protein has analgesic activity

diaDexus, Inc. - Lp-PLA2 targeted for therapeutic intervention

BrainLAB - Cleveland Clinic installs Novalis radiation therapy device

Brigham & Women's Hospital - Endothelial cells can express PD-L1, PD-L2 that downregulate activated T cells

Brigham & Women's Hospital - Neutrophil functions involving phosphorylation can be tracked with antibodies

Brigham & Women's Hospital - The calcium-sensing receptor has been implicated in cancer promotion

Brigham & Women's Hospital, Boston - Opsonophagocytic assay may be a useful test for safe enterococcal strains

Abbott Laboratories - Abbott raises AIDS drug price more than 400%

Bristol-Myers Squibb Co. - Lexicon enters neuroscience alliance for drug development

Brookhaven National Laboratory - Adenovirus proteinase interactions with viral DNA and peptide reported

Bryan Corporation - FDA grants approval of Sterile Talc Powder

Burnham Institute - TOP2A gene copy number aberration screening important with topoII-inhibitors

Burnham Institute - TR3 induces both proliferation and apoptosis

Burrill & Company - 2003 was biotech's second best year with market cap up 32%

CHU Purpan, Toulouse - The effect of estradiol on airway reactivity is dose related

CHU Vaudois - SLURP-1 is an epidermal neuromodulator; its gene is mutated in Mal de Meleda

CSIC, Cajal Institute - The enzyme aromatase helps estradiol to protect the brain from degeneration

CSIRO Biomedical Devices - New device may help premature babies

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