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Susan Hasty, Publisher Table of Contents . . . January 14th, 2004 Non-Subscriber - Summaries Only Related Areas: Other Issues in Biotech Week | Other Publications
Nippon Boehringer Ingelheim Co. - The angiogenic phenotypes of MT-8 and MT-9 murine tumors are differentAbbott Laboratories - Point-of-care diagnostics company acquired by pharmaceutical firmCalbaTech, Inc. - Molecula receives license to key RNAi patentCalifornia Dept. of Health Services - Hepatitis C and Schistosoma mansoni coinfections cause T-cell depletionCanadian Blood Services, Toronto - VIP/NTM peptide mimetics show promise for HIV treatmentCancer Research UK - MSI-low is a real phenomenon that varies in frequency among cancer typesCancer Research UK - Rare genetic condition sheds light on body's cancer defensesCardinal Health - Program designed to help hospitals, physicians slow spread of flu, SARSCardioTech International, Inc. - Medical device company announces conversion of warrantsCarnegie Mellon University - Individuals have consistent physiological responses to stressors; immune changesCarrington Laboratories, Inc. - Shareholder rights agreement amended by biotech companyCase Western Reserve University - Moxonidine effective for metabolic syndrome X treatment in ratsAble Laboratories, Inc. - FDA grants approval for Indomethacin capsulesCatholic University Leuven - Researchers describe stepwise self-organization of moleculesCatholic University of Leuven - VERSANT HIV drug resistance assay effectiveCatholic University of Louvain - The cytokine interleukin-1beta is highly expressed in SIDS brainsCedars-Sinai Medical Center - Specialist suggests pregnant women request vaccine to protect both mom and babyCelera Genomics - Chimps, humans have striking differences in genes for smell, metabolism, hearingCell Therapeutics, Inc. - Oncology company announces approval of shares listing on Nuovo MercatoCellegy Pharmaceuticals, Inc. - European regulatory authorities revoke patent related to CellegesicCellular Genomics, Inc. - Alliance signed to study kinase drug targetsCelsion Corporation - Oncology company completes $4M private placementCenix BioScience GmbH - Research deal to use genomic high throughput RNAi in human cellsAceto Corporation - Agreement signed to acquire biopharmaceutical distribution subsidiary of RocheCenter University of Orsay - Huntingtin signaling pathways regulate toxicity in Huntington diseaseCenter for Corrective Surgery - Polyester implant offers promising new outpatient treatment for snoringCenters for Disease Control & Prevention - Bat lyssaviruses from Central Asia categorizedCenters for Disease Control & Prevention - CDC releases new guidelines for hygiene in dental care settingsCenters for Disease Control & Prevention - CDC: Flu activity widespread in 45 statesCenters for Disease Control & Prevention - Cytokines act as mediators for or effectors against rotavirus diseaseCenters for Disease Control & Prevention - Health departments should adopt new notification policies for gay menCenters for Disease Control & Prevention - Herpesvirus 8 and Epstein-Barr virus seropositivity among children comparedCenters for Disease Control & Prevention - Immunohistochemical assay for babesiosis in tissue samples developedCenters for Disease Control & Prevention - Increase in rodent-transmitted disease seen in HawaiiActive Biotech AB - Positive results confirmed for tumor targeted superantigens cancer productCenters for Disease Control & Prevention - Intestinal intussusception associated with adenovirus in Mexican childrenCenters for Disease Control & Prevention - Invalid vaccine doses would cost millions to fixCenters for Disease Control & Prevention - Opsonophagocytosis assay effective for Streptococcus pneumoniae antibodiesCenters for Disease Control & Prevention - Vaccine shortages affect child immunization programsCenters for Disease Control and Prevention - Cold-adapted influenza A H9N2 reassortant is influenza vaccine candidateCentral Institute of Epidemiology, Moscow - Vaccine reduces meningococcal risk in patients with immune deficiencyCentre de Recherches du Service de Sante des Armee - Humans, rats can be tested for plague using the same, rapid serodiagnostic kitCepheid - Micro-electro-mechanical systems patent granted on multi-target chip technologyChemBridge Research Laboratories - Project milestone achieved in alliance with TanabeChemotrade, GmbH - Isonics wins key brachytherapy orderAcusphere, Inc. - Pivotal trials of AI-700 phase III clinical program initiatedChiba Cardiovascular Center - Pregnant women with repaired CHD have high arrhythmia riskChiba University - Amiodarone inhibits only sarcolemmal K-ATP channels in ventricular cellsChiba University - Endoluminal perspective volume rendering of coronary arteries aids diagnosisChildren's Hospital of Philadelphia - Targeting of chemokine receptors may help stop allograft rejectionChildren's Hospital, Westmead - Changes in the noradrenergic system underlie anorexia nervosa riskChindex International, Inc. - Supply agreement signed with Chinese hospitals for ultrasound systemsChinese Academy of Sciences - Liver cells that encode for HCRP1 avoid hepatocellular carcinomaChinese Academy of Sciences - Poly(allylamine hydrochloride) disrupts Tat-TAR RNA interactionChinese University of Hong Kong - Thrombospondin-1 causes leukemia cells to self-destructChiron Corp. - Experts: Antiquated flu vaccine system needs updatingAdvanced Cell Technology - Boston researchers create human clone embryo, magazine reportsChiron Corporation - Nonexclusive HCV license granted to Boehringer IngelheimCidra Corporation - New business venture formed to commercialize microparticle technologyCiphergen Biosystems, Inc. - Services deal signed with GE Medical Systems for ProteinChip systems ChinaCollege of New Jersey - Coping strategies help healthy women face breast, ovarian cancer riskColorado Wound Care - Diabetic patients believe protective footwear lack valueColumbia University - Genetics of food intake and body composition reviewedColumbia University - Overweight and obesity status are linked to lower life expectancyColumbia University College of Physicians & Surgeo - Interleukin-24 gene therapy shows promise in the fight against prostate cancerComGenex - New genomics screening platform technology developedCorSolutions, Inc. - CorSolutions provides programs to airline employees to reduce healthcare costsAdvion BioSciences, Inc. - $9M service contract signed for bioanalytical servicesCornell University - Influenza virus needs ubiquitin-vacuolar protein sorting, low pH for viral entryCoronado Industries, Inc. - Third European marketing agreement signed for glaucoma treatment devicesCorus Pharma - Second phase II study initiated to evaluate Corus 1030Covalent Group, Inc. - Cardiovascular safety study, other contracts total $8.1MCryoCor, Inc. - U.S. pivotal trial begins for cardiac cryoblation systemCryoLife, Inc. - Company licenses novel technology for microorganism inactivationCuraGen Corporation - Novel method for prioritizing genes for drug development publishedCutting Edge Information - Frequent sales force realignments drag down long-term effectivenessCutting Edge Information - Launching blockbuster drugs: Marketing budgets push drugs to successCutting Edge Information - Market research's role expands, aids pharmaceutical launchesAdvocate Christ Medical Center - B-type natriuretic peptide also elevated during pulmonary embolismCutting Edge Information - Report shows 85% of prescriptions never get refilledCynosure, Inc. - Pulsed dye laser receives clearance for acne treatmentCyto Pulse Sciences, Inc. - Medarex announces research and license agreement with Maryland companyCytoGenix, Inc. - Agreement signed for preclinical testing of gene-silencing antibacterial agentCytokinetics, Inc. - Collaboration signed with AstraZeneca focused on predictive toxicityCytomyx Holdings PLC - Clinomics Biosciences in agreement to be acquiredCytopia - New alliance to focus on cardiovascular disordersCytyc Corporation - 20th ThinPrep imaging system shipped to Pennsylvania hospitalDana-Farber Cancer Institute - Posttransplant survival rates for multiple myeloma patients higher after auto-SCTDanish Cancer Society - Fish intake is positively associated with breast cancer incidence rateAerogen, Inc. - Pharmaceutical company discusses aerosol delivery at AARC meetingDecision Resources, Inc. - Report: G protein-coupled receptors have significant potentialDendreon Corporation - Recently acquired San Diego operations closed by oncology firmDepomed, Inc. - Pharmaceutical company to begin trading on NASDAQ national marketDesign Continuum, Inc. - New instruments delivered to genomics companyDharmacon, Inc. - siSTABLE siRNA launched with increased stability, extended silencingDiabetex - Disease management firm changes name to XLHealthDiagnoCure, Inc. - Diagnostics company acquires assets of imaging developerDiagnostic Products Corporation - Immulite, Immulite 2000 PSA, third-generation PSA assays get CE mark approvalDigene Corporation - Application filed with FDA for approval of chlamydia testDiversa Corporation - Foreign rights expanded for product discovery from biodiversityAetna - Study examines impact of clinical guideline messaging at point of careDor BioPharma, Inc. - Davenport named VP, business development at drug delivery firmDuke University - Allograft rejection possible with antibody mediation by two different mechanismsDuke University - Cancer survives via signals from nearby blood vessels long before new vessels are grownDuke University - Having appendix removed by laparoscopy means faster recoveryDuke University - Race affects older Americans' likelihood of getting flu shotDyax Corp. - Orphan drug designation granted for DX-890Eclipse Diagnostics, Inc. - Large Scale Biology announces breakthrough diagnostic technologyEindhoven University of Technology - Mathematical model developed for arterial wall collagen fiber remodelingEmory University - Long-term B cell memory found in humans after smallpox vaccinationEndocare, Inc. - Davenport named CEO at medical device companyU.S. Food & Drug Administration - FDA plans to prohibit sales of diet supplements containing ephedraAfferent Corporation - Device company's neurotechnology improves foot sensation in diabeticsEnzo Biochem, Inc. - Gene identification company reports 73.7% gross profit marginEpix Medical, Inc. - New drug application submitted for approval of MR angiography indicationErasmus Medical Center - Drug-coated stents effective in "real world" patientsErasmus Medical Center, Rotterdam - Gene linked to type 2 diabetes in population from the NetherlandsEthicon, Inc. - FDA issues alert on counterfeit polypropylene mesh used in surgeryEuropean Inst. of Telesurgery - Surgical treatment may cure type 2 diabetesEuropean Space Agency - Solving the Ebola enigma: Satellites will provide cluesEuropean Synchrotron Radiation Facility - 3-D synchrotron radiation micro computed tomography reveals bone statusExelixis, Inc. - Investigational new drug application filed for XL119Expression Analysis - Genomic capabilities of microarray company bolstered through allianceAichi Gakuin University - Oral cavity is a reservoir of HPVs in childhoodFamily Health International - Nonlatex condoms provide a viable alternative to latex condoms for some menFibroGen, Inc. - Company initiates open-label, phase I clinical trial of FG-3019FibroGen, Inc. - Medarex announces commencement of phase I clinical trialForest Laboratories, Inc. - Lexapro receives FDA approval for generalized anxiety disorderFormatech, Inc. - Clinical supply contract manufacturer gets E.U. GMP certificationFred Hutchinson Cancer Research Center - Allo-SCT effective for myelofibrosis patientsFred Hutchinson Cancer Research Center - B lymphocyte-specific c-Myc expression sparks early events in lymphomagenesisFred Hutchinson Cancer Research Center - Histone sumoylation associated with transcriptional repressionFred Hutchinson Cancer Research Center - Protein complexes change red blood cell differentiationFrost & Sullivan - Report: Hospitals remain cautious about hiring third-party IT servicesAkers Biosciences, Inc. - Biotech company announces cancellation of sharesFudan University - Alpha-actinin may be essential for hepatitis C virus replicationFukui Medical University - Sendai virus C protein prevents gamma-activated factor from bindingFukushima Medical Univ. - Maternal serum reveals the presence of placental steroid sulfatase deficiencyGP Strategies - Valera submits NDA for Vantas, an LHRH implant for treating prostate cancerGTC Biotherapeutics, Inc. - Enrollment complete in European efficacy study for rhATIIIGen-Probe, Inc. - Testing products company announces 2004 financial guidanceGeneGo - Genomics company names Charles R. Cantor, PhD, to scientific advisory boardGenentech, Inc. - Trial yields positive results for Rituxan plus CVP chemotherapyGenetronics Biomedical Corp. - Electroporation company names Simon Benito to board of directorsGenmab, A/S - Company files IND for HuMax-CD20 to treat NHLAl Zytoona University - The prevalence of osteoporosis is high among Jordanian womenGenta, Inc. - Genasense can enhance the activity of Rituxan in NHLGenta, Inc. - Peter T. Tattle named to board of directorsGeorgetown Univ. Hospital - IgA in blood products causes anaphylaxis following transfusion in those with anti-IgAGerman Cancer Research Center - Neuroblastoma-derived sulfhydryl oxidase reverses resistance to apoptosisGerman Cancer Research Center - Soluble factors role in glioma invasion may lead to new therapiesGeron Corp. - Studies show stability, biological uniformity of different hESC linesGhana Health Service - Filariasis prevention programs are adequate for excluding pregnant womenGifu University - Handheld gene guns effect gene transfer into the beating heartGiven Imaging, Ltd. - Company reports expanded reimbursement coverage for capsule endoscopyGlaxoSmithKline - Benign prostatic hyperplasia trial to examine dutasteride in combination with alpha-blockerAlexion Pharmaceuticals, Inc. - Alliance to develop human c-MPL agonist antibody to treat thrombocytopeniaGlobeImmune, Inc. - Alex Franzusoff, PhD, named VP of researchGothenburg University - Cholera toxin protects against Clostridium difficile toxin AGreat Ormond St. Hospital for Children, London - One form of congenital neutropenia involves neutrophil elastase mutationGreystone Associates - Study: Noninvasive technologies poised for dramatic growthGuava Technologies, Inc. - Biomedical company completes $27 million in private equity financingHamamatsu University - L-asparaginase treatment may be effective for certain subtypes of AMLHarris Interactive - Survey says reduced leisure time activities may contribute to obesityHarvard Medical School - Researchers develop approaches to stop anthrax toxin actionHarvard University - African Americans are more dissatisfied than whites with healthcare systemHarvard University - Could observer bias prevent CHD diagnosis in HT users?Alkermes, Inc. - New treatment for schizophrenia may further relieve symptoms of stable patientsHarvard University - Eating more fruits and vegetables moderately lowers lung cancer riskHarvard University - HHV-7's U21 transports MHC-I molecules to lysosomes via the ER-lumenal domainHarvard University - Soy and bioactive components in tea combine to inhibit malignant progressionHarvard University - T-cell costimulatory molecules ultimately assign allograft rejection, toleranceHarvard University - Upregulation of insulin receptor substrate-2 prevents diabetesHealthpoint, Ltd. - Gillette veteran Mary Beth Dudley becomes senior HR directorHearUSA, Inc. - Hearing care company completes $7.5 million financingHebrew University of Jerusalem - The combination of high serum albumin, fibrinogen, Ig may pose a thrombotic riskHemoSense, Inc. - Deal signed for INRatio capillary test stripsHenry Ford Hospital, Detroit - Molecular effects of passive mechanical containment characterizedAllicin International - Garlic compound effective against killer MRSA "superbugs"Hiroshima University - Helicobacter pylori influences angiogenesis and gastric cancer invasionHiroshima University - Promoter methylation of cyclin D2 gene may be involved in gastric carcinomaHiroshima University - p16 Gene transfer causes abnormal nucleation in radiation-treated cancer cellsHokkaido University - H. pylori CagA inhibits B cell p53-induced apoptosis; triggers MALT lymphomaHokkaido University - Action needed to prevent alveolar echinococcosis epidemic in JapanHokkaido University - Spectratype analysis of TCR-VB repetoire may aid GVHD diagnosisHopital Necker Enfants Malades, Paris - Infant immune system finishes developing in the first year of life ex uteroHopital Necker Enfants Malades, Paris - Testing for newborn immunodeficiency is difficult; lymphocyte, Ig levels are lowHopital Notre Dame de Bon Secours, Paris - Estrogen counteracts urinary tract infections in postmenopausal womenHospital Carlos III, Madrid - Hepatitis B treatment for HIV patients reviewedAlmased USA - Nutrient selected for study of gastric bypass surgery patientsHospital Corp. of America - HCA appoints Marilyn Tavenner as group president for outpatient servicesHospital Lariboisiere, Paris - Sensitivity, specificity higher for conventional smears than for ThinPrepHospital Miguel Servet - Irinotecan is effective second-line therapy for 5-FU resistant colorectal cancerHospital Ramon y Cajal, Madrid - Nelfinavir-based HAART more durable than indinavir-based treatmentHuddinge University Hospital - Mesenchymal stem cells have useful immunomodulatory effectsHungarian Academy of Sciences - Increased nitric oxide is early sign of premature aging in diabetesHuntsman Cancer Institute - Population database may aid cancer researchISTA Pharmaceuticals, Inc. - Company achieves phase III patient enrollment goal for XibromIdenix Pharmaceuticals, Inc. - Pharmaceutical company files registration statement for proposed IPOImmtech International, Inc. - Dr. Lawrence Potempa named chief scientific officerAltana AG - Daxas to be submitted for European approval in February 2004Immucor, Inc. - Reagent company announces new bank credit facilityImmunicon Corp. - FDA 510(k) clearance granted for the CellTracks Analyzer for HIV/AIDSImmunomedics, Inc. - Presentations address humanized antibodies targeting the CD20 and CD74 antigensImperial College of Science, Technol. & Medicine - Perlecan appears to regulate some aspects of tumor angiogenesisImplant Sciences - Alternative treatment options available for prostate cancer patientsInamed Corp. - FDA dismisses two petitions seeking to delay application reviewIncara Pharmaceuticals Corp. - Drug discovery company announces 2003 net loss of $3,925,000Incyte Corp. - Patricia A. Schreck becomes general counselIndevus Pharmaceuticals, Inc. - Company's FY2003 highlighted by preparation for launch of trospium in 2004Inex Pharmaceuticals Corp. - Phase I clinical trial for encapsulated anticancer drug delayed until third quarter 2004Altus Biologics, Inc. - Milestone earned for development of malabsorption treatmentIngenium Pharmaceuticals, AG - INGENOtyping agreement inked with Max-Planck InstituteInsert Therapeutics, Inc. - Polymeric particles containing transferrin facilitate gene transferInsmed, Inc. - FDA grants orphan drug designation for rhIGF-I/rhIGFBP-3, SomatoKineInst. Polish Mothers Memorial Hospital - Apoptosis of peripheral blood cells in breast, ovarian patients examinedInst. of Cancer Prevention, Valhalla - Oral cytology differs between smokers and nonsmokersInst. of Hygiene and Tropical Medicine, Lisbon - P. jiroveci DHPS mutations not linked to sulfa drugs in Portugese patientsInst. of Microbiology & Immunology, Ljubljana - Molecular epidemiology of TB in Slovenia clarifiedInstitute Gustave Roussy - A real-time PCR assay screens for p53 recombinant adenovirus in patient samplesInstitute Gustave Roussy - IP hyperthermic chemo techniques must be draconian in order to be effectiveInstitute J Paoli I Calmettes - LIGHT, along with CD40L, allows activation of DC, IL-12 by memory T helper cellsCrucell Holland BV - Adenovirus antibodies quantified by luciferase transgene detectionAmer. Soc. For Aesthetic Plastic Surgery - Cosmetic plastic surgery predictions made for 2004Instituto Grifols - FDA license granted for intravenous immunoglobulinInstituto de Salud Carlos III - Novel trypanosomatids reported in HIV patientsInterMune, Inc. - Interim findings reported on Infergen plus Actimmune combination therapyInterleukin Genetics, Inc. - Genomics company announces management changesInternational Epidemiology Inst., Rockville - Cancer incidence seen near former nuclear materials facilities in PennsylvaniaIntranasal Technology, Inc. - Company announces newly patented lorazepam nasal delivery systemIntrogen Therapeutics, Inc. - New data highlight activity of INGN 241 drug in non-small cell lung cancerInvitrogen Corp. - Cheri Walker becomes vice president, corporate developmentInvivo Corp. - Intermagnetics agrees to acquire patient monitoring company for $22/shareInyx, Inc. - Drug delivery company enters U.S. eye care marketAmerican Cancer Society - Black men should be screened for prostate cancer at younger ageIsolagen, Inc. - Applikon collaboration leads to manufacturing system breakthroughIstituto Auxologico Italiano - Air plethysmography useful for body composition measurementIstituto Superiore di Sanita - HIV Nef induces DC differentiation through Vav signalingJagiellonian University - IL-10 release following intracerebral hemorrhage varies depending on hemisphereJichi Medical School - Plasmodium berghei circumsporozoite protein protect against malariaJohns Hopkins Univ. Hospital - AMACR is essential for optimal growth of prostate cancer cells in vitroJohns Hopkins University - A pair of discoveries helps unravel complex genetics of IBSJohns Hopkins University - Loss of keratin 6 proteins reveals filaments act during wound repairJohns Hopkins University - MeCP2, the mutated transcription factor in Rett syndrome, alters nerve synapsesJohns Hopkins University - Measles virus expressing IL-12 alters immune responses in macaquesAmerican Pharmaceutical Partners - Executive director of medical affairs appointed at pharmaceutical firmJohns Hopkins University - O-GlcNAc plays role in diabetes, cancer, and neurodegenerationJohns Hopkins University - Proteomic approach for quantitation of phosphorylation developedJohns Hopkins University - Sclerosing mesenteritis can be diagnosed, followed up by 3-dimensional CTJohns Hopkins University Hospital - In situ, invasive lobular breast carcinoma share common methylation patternsKEM Hospital, Bombay - South Indian Nadar have unique HLA alleles, others shared with South AsiansKagoshima University - Quinapril and candesartan both influence ANP outputKantonsspital Olten - Acetabular revision in total hip replacement possible without screwsKarolinska Institute - Enterococcus enriched with surface protein gene show increased adhesionKarolinska Institute - Antibiotic-resistant bacteria frequently transmitted between ICU patientsKarolinska Institute - Small interfering RNAs staunch genes associated with cancer growthAmerican Shared Hospital Services - Contract signed for 20th Gamma Knife Center in TennesseeKhon Kaen University - Optical immunoassay for group B streptococcus works better if infection is heavyKinexum, LLC - Generex hires life sciences company to help prepare for piviotal Oralin trialKishiwada Tokushukai Hospital - Carotid stenosis and peripheral artery disease common in Japanese CAD patientsKorea Institute of Radiological & Med. Science - Oxidative stress-induced apoptosis mediated by ERK1/2 phosphorylationKorea Research Inst. of Bioscience & Biotechnology - Chimeric antibodies target hepatitis B virus pre-S2 surface antigenKumamoto University - VLDL/chylomicron plays role in amyloid formationKuopio University Hospital - Efficacy of SCT against peripheral T-cell lymphoma reviewedKuopio University Hospital - IL-1 receptor antagonist polymorphisms are associated with preeclampsiaKyung Hee University - Embolization may be the optimal way to treat pelvic congestion syndromeKyung Hee University, Seoul - Animal model shows Korean herbal medicine promotes chondrocyte, bone growthAmerican Society for Microbiology - Publication provides guidance for shipping biological agentsKyushu University - The long-term effects of estrogen replacement can be predicted after a yearLa Jolla Pharmaceutical Co. - Company submits new drug application for RiquentLaboratoire de Dietetique Medicale - Very-low-calorie diet promotes long-term weight lossLaboratory Corp. - Diagnostic technology company announces stock repurchase programLam Pharmaceutical, Corp. - Chinese regulatory authorities accept application for approval of wound therapyLark Technologies, Inc. - Genaissance to acquire genomic-services companyLegacy Clinical Research & Technology Center - Subcutaneous infusions of VEGF produce new vessel growth in local implantsLeiden University - Peptide nucleic acid down-regulates microsomal triglyceride transfer proteinLeiden University - Real-time PCR is at least as effective as antigen assay to detect G. lamblia Lonza Group, Ltd. - Genentech inks Rituxan manufacturing agreementAmgen - Data suggest Aranesp benefits certain cancer patients with anemiaLorus Therapeutics, Inc. - Company publishes results of clotrimazole analogue studiesLos Alamos National Laboratory - Novel HIV viremia model may aid evaluation of drug efficacyLos Angeles County Dept. of Health Services - Baseline values of herpes zoster among children and adolescents determinedLouisiana State University - College licenses metabolic drug to Croatian companyLoyola University - New cellular, molecularly targeted agents bring hope to older AML patientsM.D. Anderson Cancer Center - Capecitabine may result in clinical and radiographic tumor responsesM.D. Anderson Cancer Center - IIp45 antagonizes IGFBP-2 stimulation of glioma cell invasionM.D. Anderson Cancer Center - PI3-K pathway may be major pathway for trastuzumab-mediated radiosensitizationM.D. Anderson Cancer Center - p27(KIP1) has a novel role in down-regulation of telomerase activityMDS Pharma Services - Butz named VP of global regulatory affairs at drug discovery firmAmylin Pharmaceuticals, Inc. - Second approvable letter issued for SymlinMaastricht University - Stressful life events rarely associated with breast cancer riskMacroChem Corp. - Trial begins for Opterone, an absorption-enhanced topical creamMahidol University - Exercise during pregnancy improves spatial learning in newborn animalsMahidol University - Hematin-targeting 9-anilinoacridines show promise as antimalarialsManaged Care Interface - Study shows controlled-release paroxetine decreases risk of discontinuationManchester Royal Eye Hospital - HSV keratitis can occur in keratoplasty as host reactivation, donor transmissionMasimo - Pulse oximetry technology performs reliably under challenging clinical motionMassachusetts General Hospital - Gender and familial associations are linked to ADHD and major depressionMassachusetts Inst. of Technology - Novel degradable polymers offer a viable alternative to other DNA vectorsMatritech - Patricia Randall becomes VP and general counsel of cancer diagnostics companyAnadys Pharmaceuticals, Inc. - Data reported from phase IB trial of IsatoribineMatsumoto Dental University - Osteoprotegerin couples with bone resorption to regulate bone formationMax Planck Institute - High-resolution solid-state NMR used to study membrane proteinsMax Planck Institute - Molecular chaperones protect parkin from oxidative stress inactivationMaxygen, Inc. - 5HTIA serotonin receptor agonists suppress P. falciparum growthMayne Pharma - NaPro completes sale of worldwide paclitaxel businessMayo Clinic - A rapid serological assay can identify amyloidogenic transthyretin variantsMayo Clinic - Gene therapy elicits tissue-specific human sodium iodide symporter expressionMayo Clinic - Incidence of coronary atherosclerosis in type 2 diabetes increasedMayo Clinic - MAPK pathway may be a potential therapeutic target in ALLMcDaniel College - Chemical modification of insulin occurs in amyloid fibrilsAncillary Care Management - Pharmacy benefits firm receives URAC health utilization management accreditationMedImmune, Inc. - Company to study therapeutic benefit of Vitaxin in prostate cancer, psoriasisMedMarket Diligence, LLC - Report: Gene therapy moving toward approval and introduction within the decadeMedMira Inc. - Company files additional data with FDA on new Reveal Rapid HIV-1 Antibody TestMedarex, Inc. - Clinical trials begin of antiangiogenesis antibody, CNTO 95Medi-Cult, a/s - Company launches commercially available in vitro maturation mediaMedical Clinic IV, Tuebingen - Tyrosine phosphatase alpha modifies insulin secretion in INS-1E cellsMedical College of Georgia - Treatment targets migraines, head and neck painMedical College of Wisconsin - Auto-SCT feasible in elderly multiple myeloma patientsMedical University of Lodz - A whole genome screen reveals five genes associated with multiple sclerosisMedicalCV, Inc. - Company reports human implant of its Northrup Universal Annuloplasty SystemAntiCancer - New imaging methods visualize important elements of tumor-induced angiogenesisMedicalCV, Inc. - Medical device manufacturer names VP of new technology developmentMedicis - FDA approves dermal filler RestylaneMedicsight, Inc. - Company reports FDA approvals, provides progress reportMedtech Insight - Report forecasts 17% annual growth in peripheral vascular stent marketMedtech Insight - Report forecasts more device-based interventions for prostate diseaseMeikai University - Mycobacteria-induced SOCS signaling impairs IFN-gamma macrophage stimulationMentor Corp. - WARF licenses botulinum toxinMerck Research Laboratories - Non-obligate chain-terminating ribonucleoside analogs inhibit HCV replicationMeridian Bioscience, Inc. - Company announces new rapid test for stomach ulcersMerrimack Pharmaceuticals, Inc. - GTC takes equity position in MM-093 developerGeron Corp. - Positive results reported for telomerase cancer vaccine clinical trialAplicare - Hemispherx expands applications for Alferon through manufacturing agreementMiami University - Adenovirus requires active proteasomes to promote late gene expressionMicrobiology & Immunology Inst., Belgrade - Staphylococcus sciuri group may be an infrequent cause of UTIMicrologix Biotech, Inc. - Company advances MBI-2401 for bacterial infectionsMie University - Caspase-8 activation is an indispensable process in TRAIL-induced apoptosisMilitary & Veterans Health Coordinating Board - Safety profile of anthrax vaccine for U.S. soldiers in Korea determinedMillennium Pharmaceuticals, Inc. - Committee recommends early end to confirmatory phase III Velcade trialMoscow State University - Local end to polio vaccination provides possible scenario for futureMountain View Pediatrics, Flagstaff - Vaccinations for the pediatric traveler reviewedMt. Sinai School of Medicine, New York - Primary biliary cirrhosis research at Mount Sinai advances due to trust, trialsMultiCell Technologies, Inc. - Stem cell licensing deal signedApplied DNA Sciences, Inc. - Biotech company brings business development veteran on boardNE Ohio University - Estrogen protects against methamphetamine-induced neurological insultNPS Pharmaceuticals, Inc. - Company begins clinical trial in migraine, appoints chief medical officerNagano Matsushiro General Hospital - Miller-Galante II coated prosthesis has good clinical, radiographic outcomesNagoya University - Liposomal delivery offers clinical gene therapy for brain tumorsNanoBio Corporation - U.S. Department of Defense awards $3.2M contract for antimicrobial nanoemulsionsNanoCure Corp. - NanoBio forms company to commercialize drug-delivery and imaging technologyNara Medical University - All-in-one cardiopulmonary bypass circuit for aortic surgery developedNational Cancer Center, Gyeonggi - BRAF mutations do not seem to be involved in gastric cancer developmentNational Cancer Center. Tokyo - Hepatocyte nuclear factor-1beta is an ovarian cancer molecular markerNational Center for Infectious Diseases - Beta fibrinogen G-455-A polymorphism is risk factor for Legg-Perthes diseaseArQule, Inc. - Oncology-focused biotech firm files $50M shelf registration statementNational Defense Medical College, Saitama - Activation of Galectin-1 gene in human hepatocellular carcinoma examinedNational Defense Medical College, Saitama - Hydrogel embedded with growth factor stimulates vascularization in vivoNational Inst. Health Science, Tokyo - Different laboratories find little variability between ELISAs for egg in foodNational Inst. for Infectious Diseases, Tokyo - Stx-liposome conjugates show promise as vaccine candidatesNational Public Health Institute, Turku - BACTEC MGIT 960 effective for TB drug resistance testingNational University of Colombia - Plasmodial EBA-140 protein peptides protect blood cells from infectionNational Yang Ming University - Amorphous oxide film has high stability, low thrombogenicityNatl. Highway Traffic Safety Admin. - Data show little change in DUI ratesNatl. Inst. of Engineering & Industrial Tech., Lis - Plasmodial aspartic protease characterizedNatl. Inst. of Health & Medical Research, Paris - HIV Nef induces accumulation of MHC II complexes and MVBsArena Pharmaceuticals, Inc. - Preclinical studies completed on obesity compoundNatl. Res. Inst. for Child Health & Development, T - Rodents with inducible suicide genes will advance liver disease drug researchNeoRx Corp. - Survival data for patients in STR phase I/II trial presentedNew York City Dept. of Health - Isoniazid effective against latent TB in HIV+ injection drug usersNew York Eye Cancer Center - High-frequency ultrasonography plays novel role in eye tumor diagnosisNew York State Dept. of Health - Murine models of human liver cancer exemplify malignant mechanismsNew York University - Modified alpha-GalCer analog has improved antimalarial, anticancer activityNew York University - The immunological synapse acts to increase low, decrease high TCR signalingNewcastle General Hospital - DJ-1 gene polymorphism not linked to Parkinson diseaseNippon Medical College - Reduced transcription of the RB2/p130 gene in human lung cancer analyzedNippon Shinyaku Co., Ltd. - The novel pyrrole derivative NS-8 suppresses voiding reflexes in animalsArray BioPharma - Oncology deal signed for development of orally active MEK inhibitorNitroMed, Inc. - Alliance formed to study pharmacologic roles of nitric oxideNoninvasive Monitoring Systems, Inc. - AT101 maker announces major narrowing of first quarter loss compared to 2002Northwick Park Hospital - Bronchoscopy with gastric washings provides optimal smear-negative pulmonary TB diagnosisNorthwick Park Hospital, Harrow - Quality of life after surgical treatment of head and neck cancers reviewedNorwegian Radium Hospital - Five-year survival rates for oral cancers have not improvedNovacea, Inc. - Target enrollment reached for phase II/III trial studying DN-101Novartis - Half a million TB patients to get free drugs under new U.N. health agency accordNovartis, AG - New data show higher dosing of Gleevec achieves higher response ratesNovo Nordisk A/S - Study shows significant reduction in blood transfusion needed in trauma patientsNovo Nordisk, A/S - Genaissance enters into HAP Technology license agreementArthritis Foundation - Top arthritis research advances of 2003 announcedNucletron B.V. - Companies to collaborate on intensity-modulated radiation therapyNutra Pharma Corp. - Acquisition to advance treatment of viral diseases and neurological disordersOXiGENE, Inc. - Company launches expansion of its R&D program in ophthalmologyOcular Sciences, Inc. - Howard Liszt appointed to board of directors of contact lens companyOita University - Neuroprotection due to HSP induction may occur with geranylgeranylacetoneOkayama University - Glutamate neurotoxicity may be blockable by a calcineurin-inhibiting peptideOkayama University - Occupational class correlates with physical activity, heart disease risk in Japanese menOraSure Technologies, Inc. - Additional data submitted to FDA for OraQuick HIV-2 claimOraSure Technologies, Inc. - FDA completes inspection of manufacturing facility for oral diagnostics companyOregon Health Sciences University - Ginkgo biloba prevents memory deficits in Alzheimer disease animal modelsAsahi University, Gifu - Subgingival Treponema glycolipids can inhibit TLR, monocyte activationOrganetix, Inc. - Biotechnology company increases production capacity of liver treatmentOsaka City University - Hepatitis C virus in tissue samples helps identify mixed up patient specimensOsaka City University - Thrombopoietin regulates early neutrophil differentiationOsaka University - Interneuronal synapse formation, actin restructuring involves cadherins, nectinsOsaka University - Tea polyphenols inhibit glucan-binding domain of glucosyltransferasesOsped Niguarda Ca Granda - Novel cytokines may simplify the management of neutropenia and anemiaOxford Health Plans, Inc. - Health plan provider expands coverage to include intranasal flu vaccinesOxford Innovation - Oxford's global network boosts healthcare in the Third WorldPPD, Inc. - Patents acquired for development of genitourinary disorder treatmentsPainCare Holdings, Inc. - Pain relief-focused company completes $10 million financingAssociation of American Medical Colleges - Group establishes new unit to study physician supply in U.S.Paladin Laboratories, Inc. - Low temperatures in Canada contribute to morbidity and mortalityPamGene International B.V. - Microarray technology company broadens scientific advisory boardPan American Health Org. - Standardized blood pressure measurement could improve hypertension carePan American Health Org. - Use of vaccine is growing worldwide, but more work remainsPanacea Pharmaceuticals, Inc. - Genomics/proteomics-based therapeutics company to develop cancer diagnostic tests in JapanPasteur Institute - Extracellular regulated kinases 1/2 are prion protein signaling targetsPaul Scherrer Institute - HIV TAT basic peptide has low affinity for VEGF receptor 2PediaMed Pharmaceuticals - PediaMed acquires multisite drug delivery platform offering multiple delivery modesPellegrin Hospital - Response to hepatitis C virus therapy can be predicted within 4 weeksPennsylvania Health Department - No further cases reported in Pennsylvania outbreakAsthma & Allergy Fdn. of America - Survey shows allergy treatment more costly due to insurance restrictions
Peregrine Pharmaceuticals - European patent granted for phospholipid vascular targeting agent programPfizer - Pharmaceutical distributors face new requirements to reduce counterfeitingPfizer, Inc. - Human Genome Sciences announces license agreementPfizer, Inc. - Pharmaceutical company to purchase up to $5 billion of common stockPharmacopeia, Inc. - Enabling science and technology firm to spin-off discovery business to stockholdersPhotogen Technologies, Inc. - Company licenses Imagent in Japan to Kyosei Pharmaceutical Co.Physicians Committee for Responsible Medicine - Twenty-seven new, life-threatening cardiac events reported by Atkins-type dietersPrana Biotechnology Limited - Alzheimer disease treatment slows progression of cognitive decline in studyPregnancyStore.com - Parents can listen to their baby's fetal heartbeat at homePrince Charles Hospital, Brisbane - Cardiovascular effects of growth hormone therapy reviewedAstraZeneca - Dynamic contrast-enhanced MRI displays how ZD6474 affects prostate tumorsPrince of Wales Hospital - Elevated PSA in prostate cancer cells may indicate tumor metastasisPrinceton University - Human cytomegalovirus coding potential reevaluatedPro-Pharmaceuticals, Inc. - Drug development company appoints new chief financial officerProMetic Life Sciences - Agreement made for development of key cancer treatment componentProctor & Gamble Pharmaceuticals - Imaging studies show risedronate preserves bone health after menopauseProtometrix, Inc. - New technology to help development of medical and diagnostic antibodiesProxima Therapeutics, Inc. - Study of partial breast irradiation in patients with DCIS announcedPurpan Hospital, Toulouse - Two stem cell transplants double chances for bone cancer survivalQiagen N.V. - Novel algorithm licensed for gene silencing applicationsQmed - FDA approves Restylane for soft tissue augmentationIntrogen Therapeutics, Inc. - INGN 241 therapy shows safety and clinical activity in phase I clinical trialAtrium - Plan expands coverage to nasal flu vaccineQuark Biotech, Inc. - Mouse strain lacking cholesterol develops with little effectQueen Elizabeth II Health Sciences Centre - Renal abnormalities common in patients who die after SCTQueens University - Hypogonadism correction offers men several mental and physical benefitsRTI International, North Carolina - Inhaled tertiary amyl methyl ether vapor affects reproduction in male rodentsRadiancy, Inc. - FDA grants clearance for light unit assembly acne vulgaris treatmentRoche - 48-Week data submitted to FDA for full approval of HIV fusion inhibitorRoche - FDA approves labeling for use of Xenical in adolescent patientsRoche - Losing weight with Xenical cuts threat of developing type 2 diabetesRoche Diagnostics - Genetic disorder tests receive FDA clearance and CE MarkRoche Diagnostics Corp. - New 3-year hospital blood glucose contract awardedAtrix Laboratories, Inc. - Drug delivery company adopts Rule 10B5-1 policyRockefeller University - Cholesterol-regulated SREBP and LXR target genes identified in miceRowett Research Inst. - CSF treatments, laser light therapy may aid restitution and repair of mucositisRoyal Free & Univ. College Medical School - Adeno-associated viruses suitable for therapy must be devoid of contaminationRoyal Free Univ. College Medical School - Treatment of amyloidosis may involve targeting of proteins or disease processRoyal Prince Alfred Hospital - Bone invasion alone doesn't predict survival rates for oral cancer patientsRubicon Medical Corp. - Medical device manufacturer names new VP of regulatory and clinical affairsRutgers State University - Enzyme induction, dietary chemicals may be approaches to cancer chemopreventionSA Water Corporation - Methods for counting water-borne bacteria comparedSaegis Pharmaceuticals, Inc. - CNS-focused biopharmaceutical company announces new vice presidentSan Bortolo Hospital - Growth hormone prevents skeletal muscle atrophy in ratsAutonomous University of Madrid - In rheumatoid synovitis, early fibrin deposition should be targeted for therapySangamo BioSciences, Inc. - Oncolytic vector technology licensed for development of cancer therapySanquin Blood Supply Fdn. - Genmab joins with Dutch nonprofit to improve hemophilia treatmentSchering AG - New drug application submitted to FDA for lower-dose YasminSchering, AG - MS-325 for magnetic resonance angiography submitted for approval in the U.S.Schering-Plough Corp. - Study: Noxafil demonstrates significantly better outcomeScienceBased Health - New study finds HydroEye beneficial to LASIK patientsScripps Research Institute - Cocaine-binding scFv antibody can be made in E. coli , purified, freeze-driedScripps Research Institute - Regenerative chemical turns muscle cells into stem cellsSeattle Biomedical Research Institute - Gates Foundation gives $10 million grant to develop pregnancy malaria vaccineSeattle Genetics, Inc. - Antibody-drug conjugate collaboration designates additional antigen targetsAvanir Pharmaceuticals - Pharmaceutical firm reports lower revenues, provides clinical updateSecond Military Medical University, Shanghai - Effects of clonidine mediated by NMDA receptors in RVLMSeitoku University - Numerical methods are adequate for estimating dietary iron requirementsSemBioSys Genetics Inc. - Development agreement executed with Martek BiosciencesSequenom, Inc. - Genetics company announces osteoporosis collaborationShire Pharmaceuticals Group plc - Agrylin licensed in Japan for treatment of thrombocythemiaShowa University - Novel method facilitates small dense LDL quantificationSilesian School of Medicine - Phalangeal quantitative ultrasound delineates women with nontraumatic fracturesSkinvisible, Inc. - Hand sanitizer provides greater than 99% kill against influenza A in studiesSkyePharma, PLC - Study: Patients treated with Paxil CR are less likely to discontinue therapySolove Research Institute - Researchers get easy access to leukemia gene informationAventis - Molecular cytogenetics alliance formed to validate cancer drug targetsSomaLogic, Inc. - Japanese corporations invest $11 million in proteomics companySosei Co. Ltd. - Japanese biopharmaceutical company co-promotes prostate cancer treatmentSouthern Arizona VA Health Care System Hospital - AT1 blockade enhances vasorelaxation during heart failureSpectRx, Inc. - FDA grants second major patent for insulin delivery patchSpectral Diagnostics Inc. - Companies form joint venture for R&D of infectious diseases diagnosticsSpectrum Pharmaceuticals, Inc. - Abbreviated new drug application filed with FDA for FluconazoleSports Orthopedics & Spine, Jackson - Modified Neviaser portal safer due to positionSt. Jude Children's Hospital - Pharmacokinetic models are important for childhood cancer drug developmentSt. Jude Children's Hospital - Usefulness of FISH in morphologically ambiguous gliomas examinedSt. Jude Children's Hospital, Memphis - Etoposide treatment triggers chimeric Mll gene fusions in vitroAventis - Nautilus Biotech reaches milestone in vaccine collaborationStanford University - Expanding public insurance for HIV/AIDS could markedly increase survival ratesStanford University - Pediatric renal graft loss linked to non-adherence, teenage, mental illnessStanford University - Relationship between technology availability, healthcare spending analyzedStanford University - VEGF is a prerequisite for exercise-induced hippocampal neurogenesisState Univ. of New York, Albany - Culture, demography, and biology interact to determine genetic trait prevalenceState Univ. of New York, Buffalo - Utilization of virtual reality for endotracheal intubation training evaluatedState University of New York, Buffalo - Epidemiology of severe respiratory syncytial virus infection reviewedState University of New York, Buffalo - Lung cancer is not associated with lifetime total alcohol consumptionStatens Serum Institute - Greenlandic Inuit have increased incidences of several cancersSterion Incorporated - Medical products company reports fiscal 2003 and fourth quarter resultsAventis Pasteur - FDA investigating reports of unlicensed influenza vaccineStructural GenomiX, Inc. - Biotech companies join to develop treatments for urological cancersStryker Corporation - Medical product manufacturer announces production facility expansionsSuntory Pharmaceutical Research - HMGene enters obesity drug agreementSyneron Medical, Ltd. - FDA approves Polaris WR wrinkle treatment systemTechnical University of Lodz - Microwave energy dose affects immunoreactivity of gliadin and wheat flourTechnology Foundation STW - Tumor growth model estimates risk of cancerTemple University - Dysphagia, hoarseness among risks of anterior cervical diskectomy and fusionTetracore, Inc. - First FDA-cleared laboratory test for Bacillus anthracis Texas Tech University - Researchers find low levels of perchlorate in evaporated milk samplesThames Water Utility - Immunomagnetic-based method detects Cryptosporidium , Giardia oocystsAvitar, Inc. - Oral fluid diagnostics company sells laboratory subsidiaryThe Boston Consulting Group - Patients skip doses of prescribed drugs on purposeThe Speedel Group - Cardiovascular/metabolic disease-focused company opens representative office in JapanTiax - U.S. patent issued for multilayered dressingTohoku University, Japan - II beta-hydroxysteroid dehydrogenase type 2 is expressed in ARDS patient lungsTokyo Medical & Dental University - Prefabrication of bone flap induced by bone morphogenetic protein 2Tokyo Medical & Dental University - Regions of Epstein-Barr virus protein activate NF-kappa BTokyo Metropolitan Neurology Hospital - Neurons in Duchenne, myotonic dystrophy have excess non-cholinergic synapsesTottori University - Intraoperative GH measurement helps boost safety of secondary transnasal surgeryTransplant Clinic, Halifax - Acute kidney rejection is lower with basiliximab, independent of cyclosporineTreviglio Hospital - Effort needed to develop new prophylaxis, treatment for venous thromboembolismAxcan Pharma, Inc. - CPMP positive opinion issued in Europe for PhotobarrTrigen, Ltd. - Data presented on neutralizing agent for anticoagulant direct thrombin inhibitorsTrimedyne, Inc. - Lumenis litigation settledTripler Army Medical Center - Treatment of lower extremity injuries due to land mines examinedTufts University - Linezolid does not raise thrombocytopenia risk in nosocomial pneumonia patientsU.S. Dept. of Health & Human Services - National reports on quality, disparities in healthcare services use releasedU.S. Food & Drug Administration - Drug carcinogenicity determined using structural similarity and E-state indexU.S. Food & Drug Administration - Liquid chromatography method for impurities in methoxsalen developedU.S. Food & Drug Administration - Rapid identification method for E. coli O157:H7 using real-time PCR developedU.S. Food & Drug Administration - U.S. officials say it's too costly to legalize drug importsU.S. Food & Drug Administration - galE gene in campylobacters linked to Guillain-Barre syndromeAxonyx, Inc. - Scope of Phenserine trial; sub-study to include brain scansU.S. National Cancer Institute - Occupational cancer among women: Where have we been and where are we going?U.S. National Cancer Institute - Skin capillary endothelium SDF-1 plays key role in Kaposi sarcoma pathogenesisU.S. National Cancer Institute - Studies evaluating fenretinide are underwayU.S. National Institutes of Health - Anti-HIV alkaloids isolated from Monanchora spongeU.S. National Institutes of Health - Common variable immunodeficiency may be treatable with B lymphocyte stimulatorU.S. National Institutes of Health - Large animal models have advantages in drug, tolerance transplantation researchU.S. National Institutes of Health - Multiple gene and clade HIV-1 DNA vaccines broaden immune responseU.S. National Institutes of Health - NHGRI launches social and behavioral research branchU.S. National Institutes of Health - NK cell activating receptor NKp46 is similar to other leukocyte receptorsU.S. National Institutes of Health - Strand-specific RNA synthesis defects found in mutated poliovirus510-262-8757 - $15M milestone payment awarded for developments in anticancer compoundAzienda Osped San Camillo Forlanini - Intragastric balloon effective for weight loss in obese patientsU.S. National Institutes of Health - Teen drug abuse declines across wide frontU.S. Natl. Inst. of Child Health & Human Developme - U.S. NIH alerts parents to winter SIDS riskU.S. Natl. Inst. of Environmental Health Sciences - Some CpG G:C-A:T transitions may be caused by smokingU.S. Natl. Inst. of Standards & Technology - Test method provides biocompatibility "barometer"U.S. Naval Medical Center - Obesity linked to aggressive prostate cancerU.S. Naval Medical Research Ctr. Detachment, Lima - Primaquine effective for prevention of malaria in travelersULB Erasme - Minocycline activates the tetracycline-responsive promoter in treated cellsUllevaal University Hospital - HAART has limited effect on hypertension riskUmea University - Bone inductive substances improve new bone formation where estrogen is absentUnipath, Ltd. - Inverness to supply Pfizer with a digital version of its e.p.t pregnancy testBaptist Health System, Birmingham - Alabama system names new president and CEOUnited Nations - Campaign gathers pace on both sides of front lineUnited Nations - Ethiopia minister blasts doctor's group over treatmentUnited Nations - Thousands threatened by epidemic in southern AfricaUnited Nations - U.S. labor secretary launches HIV/AIDS initiative in GhanaUniv of Alabama, Birmingham - Hepatitis C virus infection may encourage the formation of diabetic amyotrophyUniv. Autonoma of Nuevo Leon - Peyote cactus extract can activate NO, increase cytokines, kill tumor cellsUniv. Hospitals Gasthuisberg, Leuven - Chorioamniotic membrane separations follow invasive intrauterine proceduresUniv. of A Avogadro Piemonte Orientale - Recent insights on the mechanisms of liver preconditioning evaluatedUniv. of Alabama, Birmingham - Oncolytic viruses used as vectors for treatment of malignant gliomasUniv. of British Columbia - Neutralizing antibodies to IFN beta-1b therapy for relapsing-remitting MS may affect outcomeBar Ilan University, Ramat Gan - Apoptotic cell shrinkage can be tracked in individual lymphocytes by stainingUniv. of California, Berkeley - Single gene plays key role in neural tube defectsUniv. of California, Davis - Wild-type p53 in prostate tumor cells may reduce the effectiveness of radiationUniv. of California, Irvine - Down syndrome study reveals possible method for detecting initial stages of ADUniv. of California, Los Angeles - Drug resistance remains a major clinical challenge in multiple myelomaUniv. of California, Los Angeles - Shyness can be deadlyUniv. of California, Riverside - Rapid botulinum toxin type B microsensor developedUniv. of California, San Diego - Microarrays reveal macrophage gene expression after TB infectionUniv. of California, San Diego - Short T2 components may show high signals in many tissuesUniv. of California, San Francisco - Mitosis by activated protein kinase B involves polo-like kinase 1Univ. of California, San Francisco - Synthetic cysteine protease inhibitors have potent antimalarial activityBarr Laboratories, Inc. - FDA panel votes to allow sale of emergency contraceptiveUniv. of Complutense, Madrid - Bulimia nervosa patients and normal eaters have similar 5-HTT gene mutationsUniv. of Erlangen Nurnberg - Diagnosis of different paraproteinemias requires extensive renal histologyUniv. of Iowa Hospitals & Clinics - Interventions needed to promote adoption of evidence-based acute pain managementUniv. of Medical Science, Poznan - Novel mutation found in patient with Treacher Collins syndromeUniv. of Nottingham Hospital - Contact lenses can relieve pain, promote healingUniv. of Rochester Medical Center - Study finds many early-stage breast cancer patients not completing chemotherapyUniv. of Sacred Heart, Rome - Gemcitabine effective alone or in combination with carboplatin, paclitaxelUniv. of Southern California - Dermal-epidermal junction type VII collagen produced by fibroblastsUniv. of Texas Health Science Center - Radiotherapy may be effective alternative, adjunct in treating head, neck cancerUniv. of Texas Medical Branch - Butyrate can inhibit pancreatic cancer metastasis by inhibiting P4 integrinBayer Pharmaceuticals Corp. - FDA grants Cipro additional 6 months marketing exclusivityUniv. of Texas Medical Branch - DNA base excision repair proteins help fix oxidative DNA damageUniv. of Texas SW Medical Center - Dallas barbers become blood-pressure specialists for African American menUniv. of Texas SW Medical Center - LDL receptor-related protein controls blood-brain barrier permeabilityUniv. of Texas SW Medical Center - Piccolo proteins pique neuronsUniv. of Texas SW Medical Center - Researchers discover first effective treatment for exercise disorderUniv. of Western Ontario - Vascular changes prevail in disorders that host chronic neuroinflammationUniversit Paris-Sud - Nerve degeneration in familial amyloid polyneuropathy studiedUniversitat Heidelberg - Niemann-Pick disease type C caused by disturbed lipid transportUniversitats Augenklinik Essen - Thyroid-associated ophthalmopathy can be treated by anti-inflammatories, surgeryUniversity Clinic Schleswig - Prostatectomy and radiotherapy present similar quality of life outcomesBaylor College of Medicine - Bone mineral mass not decreased in overweight and obese childrenUniversity Hospital Dusseldorf - Toxin-gene profile heterogeneity found in group A streptococcusUniversity Hospital Zurich - Overt thyroid disorders must be managed during pregnancyUniversity Hospital, Bordeaux - Potential genetic links to diabetes and cardiovascular disease discoveredUniversity Hospital, Nottingham - Pharmacological therapy for chronic heart failure reviewedUniversity Hospital, Orebro - Low incidence of non-Hodgkin lymphoma in Sweden may result from carcinogen bansUniversity Hospital, Pamplona - Vaginal reconstruction by modified rectus abdominis musculocutaneous flapUniversity Hospital, Uppsala - Regimen of HiDAC, AMSA and G-CSF provides efficient stem cell mobilizationUniversity Hospital, Vienna - Circulating tuberculostearic acid may aid TB diagnosisUniversity Kebangsaan Malaysia - Imperforate hymen may have familial originsUniversity Medical Center, Nijmegen - Donor lymphocyte infusions effective against post-SCT indolent NHLBaylor College of Medicine - Broadly applicable heat shock protein-mediated tumor vaccine developedUniversity at Buffalo - Husband's drinking behavior influences social life of newlywedsUniversity of Aberdeen - Sublingual or vaginal misoprostol combines with mifepristone to abort pregnancyUniversity of Alabama - Delta-class GST from DDT-resistant An. gambiae characterizedUniversity of Alberta - Late rejection may still be due to antibodies; diagnostics, cures are neededUniversity of Alberta - TRAIL triggers apoptosis in human malignant glioma cellsUniversity of Arkansas - Scientist finds how cancer triggers bone disease, eyes treatmentUniversity of Auckland - Crystal structure of M. tuberculosis MshB protein characterizedUniversity of Barcelona - Chemoembolization improves survival for many with unresectable liver cancerUniversity of Bern - Activated gamma delta T cells go to lymph nodes; increase antibody productionUniversity of Bern - Women with hereditary risk for thrombophilia need preconception screeningBeckman Coulter, Inc. - Garrett named president, chief operating officer at biomedical companyUniversity of Birmingham - Birt-Hogg-Dube in activation occurs in some renal cell, colorectal cancersUniversity of Birmingham - Crystal structure of M. tuberculosis FbpC1 characterizedUniversity of Bonn - Epigenetic silencing of HIC-1 may play role in most medulloblastomasUniversity of Bradford - Transformation into gamma-lactone augments quassin's antimalarial activityUniversity of British Columbia - T-plastin shows potential as Sezary cell-specific markerUniversity of Buenos Aires Paraguay 2155 - Free fatty acids induce cell differentiation in Trypanosoma cruzi University of Calabria - Human sirtuin 3 gene plays role in longevityUniversity of California-Los Angeles - 12-Lipoxygenase plays role in experimental diabetic nephropathyUniversity of Cambridge - Intercellular adhesion molecule-1 gene associated with type 1 diabetesUniversity of Carabobo - Control measures of Lutzomyia longipalpis s.l. in Venezuela outlinedBest Practices, LLC - Report reveals how companies optimize biomarker researchUniversity of Chicago - Methylnaltrexone inhibits opioid-mediated HIV macrophage infectionUniversity of Cincinnati - Protein kinase C alpha impairs ventricular function during cardiac hypertrophyUniversity of Colorado - Desflurane general anesthesia alters hepatic venous pressureUniversity of Colorado - Specific T cells occur in lung, not circulation, in chronic beryllium diseaseUniversity of Connecticut - New ex ova models are expected to enhance preclinical research effortsUniversity of Copenhagen - Body composition measurement may help therapy choice for obesityUniversity of Copenhagen - Glucagon-like peptide 2 may have clinical use in short-bowel syndromeUniversity of Cordoba - ApoE gene promoter -219G/T mutation alters postprandial TRL metabolismUniversity of Edinburgh - Novel homeobox gene identified in embryonic stem cellsUniversity of Edinburgh - TNF-alpha may play an early role in the malignant transformation of liver cellsBharathiar University - Gymnema montanum leaves possess antidiabetic effectUniversity of Essen Gesamthsch. - Orthotopic bladder replacement for advanced cancer shows great long-term resultsUniversity of Essex - High-intensity exercise such as shoveling snow can be a danger to your heartUniversity of Florida - Cancer more likely to recur in blacksUniversity of Florida - Strong families enjoy most support from those who find it difficultUniversity of Genoa - Human natural killer cells patrol for aberrant HLA-I expression, kill deviantsUniversity of Glasgow - Trypanosoma homologous recombination changes if mismatch repair is impairedUniversity of Glasgow - Chondrosarcoma of the hand behave differently than other chondrosarcomasUniversity of Groningen Hospital - Novel hyaluronan-based biomaterials support nerve repairUniversity of Haifa - Changes in marital relationships among parents of children with cancer examinedUniversity of Heidelberg - Differentiating intraocular inflammation, infection can be done by vitrectomyAEterna Laboratories, Inc. - Neovastat's clinical development plan updatedBioMer, C.V. - Merck, KgaA, to exit orthopedics joint venture to focus on core businessesUniversity of Heidelberg - Imiquimod 5% cream effective against viral wartsUniversity of Heidelberg - There are many uses for single, combined therapeutic vitrectomy for uveitisUniversity of Hong Kong - Nonmyeloablative SCT from kidney donor can resolve PTLDUniversity of Hong Kong - Proangiogenic cytokine regulates vascular remodeling during chronic hypoxiaUniversity of Hong Kong - Survivin halts gastric cancer tumorigenicity and angiogenesisUniversity of Hull - Cholesterol paradox: Lower values bad omen for heart failure patientsUniversity of Illinois - Cell's motor is a mountain climber, not an inchwormUniversity of Illinois - Modified GFP reporter-based assay useful for anti-TB drug screeningUniversity of Innsbruck - Gamma-aminobutyric acid receptor expression increased in epilepsyUniversity of Ioannina - Isolated intraparotid Kaposi sarcoma possible during effective HIV treatmentBioMicro Systems - New microarray hybridization chamber launchedUniversity of Kiel - Sacral neuromodulation beneficial for patients with neurogenic urinary retentionUniversity of Kuopio - New MRI contrasts discern response to gene therapy in rodent glioma modelsUniversity of Laval - LDL peak particle diameter is highly heritableUniversity of Leipzig - Electronic endocardium mapping reviewedUniversity of Liverpool - Molecular assay aids identification of An. minimus vectorsUniversity of Liverpool - Oral ulceration may indicate Behcet disease, inflammatory bowel syndromeUniversity of London - Balance of activator, inhibitor Fc gamma receptors may influence kidney diseaseUniversity of London - Complement deposition may soon be blockable; to stop kidney pathology, rejectionUniversity of London Birkbeck College - Crystal structure of truncated human beta B1-crystallin reportedUniversity of Lund Hospital - Cancer cells are characterized by having aberrant chromosomesBioNumerik Pharmaceuticals, Inc. - Mechanism-based drug discovery firm raises $29M in private placementUniversity of Madrid - Early antiretroviral treatment is neuroprotective in vertically infected childrenUniversity of Malta - Select vitamin D receptor gene changes don't obscure bone mineral indicesUniversity of Manchester - Mammary epithelial cells express the osteopontin mediator Runx2University of Maryland - Inhibition of histone deacetylase increases cytotoxicity to anticancer drugsUniversity of Maryland - U.S. officials say interviews for HIV study were fabricatedUniversity of Massachusetts - In CSR, mutation rates and patterns differ greatly, depending on the regionUniversity of Michigan - Doctors more likely to prescribe pricey new drugs despite standardsUniversity of Michigan - Intranasal RANTES/CCL5 chimera plus truncated exotoxin may prevent fungal asthmaUniversity of Michigan - Scientists discover how anthrax creates its deadly sporesUniversity of Michigan - Study: Reduced FDA resources cause of decline in drug approval timesBioPoint Solutions, Inc. - New company launched to help biotech, pharma firms handle data managementUniversity of Milan - Kit elements needed for stem-cell expression identifiedUniversity of Milan - Neurons of dorsal motor vagal nucleus show hypoxia-related marker in SIDS brainsUniversity of Milan - TIPS improves cardiac function in hypovolemic patientsUniversity of Milan Bicocca - Effects of aging on cardiovascular system reviewedUniversity of Minnesota - Arsenic trioxide increases the thermosensitivity of tumorsUniversity of Minnesota - Environmental tobacco smoke significantly affects nonsmokersUniversity of Munich - A new B*38 allele, B*3809, was found in a Dutch caucasoid B-cell lineUniversity of Munich - Prostate cancer and erectile dysfunction. Which therapy when?University of Munich - Time spent learning how to treat foreign patients would ultimately reduce costsUniversity of Murcia - Microangiogenesis facilitates parkinsonismBioVisioN AG - Peptidomics company names new chief scientific officerUniversity of Naples Federico II - Consolidation therapy improves sustained response in HCV genotype 1b patientsUniversity of New South Wales - DHEA increases macrophage foam-cell formationUniversity of Newcastle - Protein A-tagging allows purification of complexes from Candida University of North Carolina - Study reveals few problems banning smoking at schoolsUniversity of Northern Iowa - Morning glory extract has antituberculosis activityUniversity of Nottingham - Maternal undernutrition doesn't correlate with infant birth weight indicesUniversity of Ouagadougou - Burkina Faso medical plants have antimalarial activityUniversity of Oxford - Intracellular localization of self-antigen promotes autoreactive B cellsUniversity of Oxford - Recombinant SP-D can improve surfactant replacement therapy in neonatal lungsUniversity of Oxford - Two-brood P. falciparum replication during quinine treatment suspectedBioanalytical Systems, Inc. - Contract research organization reports 23% increase in revenueUniversity of Padua - Sudden-death risk tracked in large, long-running study of young athletesUniversity of Paris - 3-D ultrasound assesses lung volume in cases of congenital diaphragmatic herniaUniversity of Paris - Innervation may be early target in type 1 diabetesUniversity of Pennsylvania - Alloimmunity may be controllable by targeting cell-cycle regulatorsUniversity of Pennsylvania - Sociocultural influences may affect genetic testing among African American womenUniversity of Pittsburgh - Allotrap peptide RDP58 inhibits aortic graft arteriosclerosisUniversity of Pittsburgh - Alveolar macrophage killing of P. carinii depends on Dectin-1 beta-glucan receptorUniversity of Pittsburgh - Degradation of angiotensin II in kidneys characterizedUniversity of Pittsburgh - Early hormone replacement is fundamental to limiting cognitive declineUniversity of Pittsburgh - Gadd45a contributes to p53 stabilization in response to DNA damageBioject Medical Technologies - Phase I study completed comparing needle-free system to traditional syringeUniversity of Pittsburgh - Miscommunication and poor medical advice contributes to unplanned pregnanciesUniversity of Pittsburgh - Patients diagnosed with hip fracture are not receiving adequate follow-upUniversity of Pittsburgh - Researchers study broccoli-derived chemicals to prevent cancerUniversity of Portsmouth - Short-term meningioma cultures express key matrix metalloproteinasesUniversity of Rochester - Pseudomonas aeruginosa has two quorum sensing systems that could be targetedUniversity of Rochester - Embolization highly effective, minimally invasive to control bleedingUniversity of Roma Tor Vergata - Diagnosis of obesity cannot be based on body mass index aloneUniversity of Rostock - Renal biopsy histology does not correlate highly with most clinical syndromesUniversity of So. Denmark - PPARdelta transactivation occurs in psoriasis; may be linked to pathologyUniversity of South Dakota - Thyroid hormone treatment improves cardiopulmonary function in male SHHF ratsBiomet, Inc. - FDA clears Palacos G antibiotic-loaded bone cementUniversity of South Florida - Managing older chemo patients involves preventing pharmacologic complicationsUniversity of South Florida - Notch signaling necessary but not sufficient for dendritic cell differentiationUniversity of Southern California - "Paper of the year" recognizes significance of gene variance findingsUniversity of Southern California - Lycopene inhibits the growth of normal human prostate epithelial cells in vitroUniversity of Szeged - A whole genome screen reveals 33 genes associated with multiple sclerosisUniversity of Texas - New adenoviral vector technology wins patent; Introgen gets licenseUniversity of Tokushima - Overexpression of TSC2 may exert the antitumor effect on oral cancer cellsUniversity of Tokyo - CO poisoning is due to ROS affecting neurons; hypothermia can reduce the damageUniversity of Tokyo - Hepatitis C virus core protein upregulates TGF-beta1 transcriptionUniversity of Tokyo - Male gender heightens risk of after hematopoetic SCT late-onset hemorrhagic cystitisBiomira, Inc. - Cancer drug development status reportedUniversity of Tokyo - Microarray analysis should prove useful for identifying tumor markersUniversity of Toronto - An automatic technique for breast symmetry detection presentedUniversity of Toronto - Genetics research could spawn further creation of targeted, nontoxic therapiesUniversity of Toronto - New understanding of why brain cells die after stroke will lead to new treatmentsUniversity of Tsukuba - Dentists must be diligent in recognizing ulcerative lesions, small oral cancersUniversity of Tubingen - CD8 T cells expanded on calibrated MHC/anti-CD28-coated microspheresUniversity of Turin - Most in situ breast cancers represent focal lesions derived from single cloneUniversity of Turin - Response to ghrelin administration decreased in human obesityUniversity of Turku - Finish study finds many physicians skeptical about complementary therapiesUniversity of Ulster - Kinestatin is novel bradykinin B-2 receptor antagonist peptideBiophan Technologies, Inc. - Nanomagnetic particles used as contrast agent improves detailUniversity of Uppsala Hospital - Neuropsychological assessment useful as complement to neurological examUniversity of Utrecht - Increased systemic temperature seen during regional hyperthermiaUniversity of Vienna - Lipid oxidation products have both pro and anti-inflammatory effectsUniversity of Washington - Antifungals affect gene expression in pathways of Candida albicans University of Washington - Genetic loci linked to LDL size and TG levels in FHTG identifiedUniversity of Wisconsin - Stem cells illuminate early stages of human developmentUniversity of Wisconsin - Time profile of L-dopa metabolites in nonhuman primates determinedUniversity of Wisconsin, Madison - Influenza immunization decreases CYP3A4 activity in vivoUniversity of Witwatersrand - Aflatoxin B-1 and hepatitis B virus synergize to encourage hepatocarcinogenesisUniversity of Wurzburg - Skin inflammation, cancer therapy may benefit from targeting the lymphocyte pathAbbott Laboratories - A reversible inhibitor of methionine aminopeptidase-2 quells tumor growthBirmingham Heartlands Hospital - A new line probe assay identifies hepatitis B virus precore variants in seraUniversity of Zurich - Nuclear factor-kappa B dependent gene expression involves p300, PARP-1University of the Sacred Heart, Rome - Apolipoprotein E is a nerve recovery and neovascularization intermediaryV Segalen University - Chromosomal imbalances indicate tumor relapse in cutaneous CD30+ T-cell lymphomaVA Medical Center, Kansas City - 2-Methoxyestradiol has a biphasic effect on new vessel growthVA Medical Center, Minneapolis - High-sodium diet has blood pressure-independent adverse vascular effectsVanderbilt University - Antiretroviral treatment increases oxidative stressVanderbilt University - Imaging mass spectrometry allows profiling and imaging of proteinsVanderbilt University - Organic anion-transporting polypeptide plays role in drug dispositionVanderbilt University - Soluble EphA receptors stop VEGF-dependent tumor angiogenesisVanderbilt University - p63 Amplification, overexpression occurs early in developing lung cancerBloomberg School of Public Health - Children get better care with developmental specialists on physician teamVertex Pharmaceuticals Inc. - University and pharmaceutical company form drug discovery collaborationVertex Pharmaceuticals Incorporated - Investigational drug, merimepodib, well tolerated in hepatitis C clinical trialVirRx, Inc. - Oncolytic viral technology licensed to Introgen TherapeuticsVirginia Commonwealth University - Immunosuppressant FTY720 may be phosphorylated by sphingosine kinase type 2W. Australian Ctr. for Pathology & Medical Researc - PCR assay can aid malaria diagnosis in patients with low parasitemiaWakayama Medical University - Hormone receptor status and tumor vessels change with endometrial progressionWake Forest University - Obesity increases risk for thrombotic thrombocytopenic purpuraWalter Reed Army Inst of Research - Leukocyte DNA fragmentation may be diagnostic for low exposure to nerve agentWashington Homeopathic Products - Some turn to homeopathic remedies to combat fluWashington University - Cryptococcus neoformans capsule formation can be blocked by RNA interferenceBoston Biomedica, Inc. - Diagnostic kit gets FDA approvalWashington University - Hydroxychloroquine effective as GVHD prophylaxis after unrelated transplantWashington University - Major differences between pediatric, adult meningeal tumors reportedWayne State University - Positioning of prostate cancer patients during radiotherapy studiedWayne State University - Scientists provides new insights into basis of diabetic neuropathyWayne State University - Sphingolipids may be an alternative to conventional drugsWeill-Cornell Medical Center - Potassium iodide should be available to people living near nuclear power plantsWelch Foods, Inc. - Concord grape juice improved memory, neuromotor skills in animal studyWellcome Trust Laboratories, Chichiri - Schistosomiasis does not affect NTS bacteremia outcome in HIV+ Malawian adultsWest Virginia University - p38 MAPK mediates negative inotropic effect of gp120 on myocytesWestmead Hospital, New South Wales - CnLYSO1 is an extracellular lysophospholipase of Cryptococcus neoformans Boston University - Antibody- and RNA-based HIV testing should be offered to suspected patientsWhitehead Institute - Mad cow mechanism may be integral to storing memoryWistar Institute - Chemokines and TRANCE act as genetic adjuvants for rabies DNA vaccineWomen's Capital Corp. - Women are not likely to abuse over-the-counter emergency contraceptionWorld Health Organization - HIV has significant influence on leishmaniasis epidemiologyWorld Health Organization - U.N.: Spread of polio in West Africa threatens global eradication driveWorld Health Organization - WHO: Battle against AIDS will founder without boost to basic healthcareWyeth - National survey shows coughs keep Americans away at work, home, and playWyeth Ayerst Research - Antigen-coating concentration affects presentation of Neisseria epitopesWyeth Pharmaceuticals - CDC: Vaccine shortage likelyYale University - Brain area that regulates emotions is smaller in manic-depressive peopleBradley Pharmaceuticals, Inc. - Pharmaceutical company signs agreement for probiotics developmentYale University - Hormone imbalances contribute to bone loss in lactating mammalsYale University - Hoxa10 transcription factor mediates endometrial differentiationYale University - Natural killer T cells are responsible for skin allergiesYale University - Protein tyrosine phosphatases in nervous system reviewedYale University - Well-tolerated mobilization regimen effective for multiple myeloma patientsYork Nutritional Laboratories - Home metabolic analysis kit now availableZhejiang University - Conotoxin MVIIA and thioredoxin fusion protein has analgesic activitydiaDexus, Inc. - Lp-PLA2 targeted for therapeutic interventionBrainLAB - Cleveland Clinic installs Novalis radiation therapy deviceBrigham & Women's Hospital - Endothelial cells can express PD-L1, PD-L2 that downregulate activated T cellsBrigham & Women's Hospital - Neutrophil functions involving phosphorylation can be tracked with antibodiesBrigham & Women's Hospital - The calcium-sensing receptor has been implicated in cancer promotionBrigham & Women's Hospital, Boston - Opsonophagocytic assay may be a useful test for safe enterococcal strainsAbbott Laboratories - Abbott raises AIDS drug price more than 400%Bristol-Myers Squibb Co. - Lexicon enters neuroscience alliance for drug developmentBrookhaven National Laboratory - Adenovirus proteinase interactions with viral DNA and peptide reportedBryan Corporation - FDA grants approval of Sterile Talc PowderBurnham Institute - TOP2A gene copy number aberration screening important with topoII-inhibitorsBurnham Institute - TR3 induces both proliferation and apoptosisBurrill & Company - 2003 was biotech's second best year with market cap up 32%CHU Purpan, Toulouse - The effect of estradiol on airway reactivity is dose relatedCHU Vaudois - SLURP-1 is an epidermal neuromodulator; its gene is mutated in Mal de MeledaCSIC, Cajal Institute - The enzyme aromatase helps estradiol to protect the brain from degenerationCSIRO Biomedical Devices - New device may help premature babies
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