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California Dept. of Health Services
Hepatitis C and Schistosoma mansoni coinfections cause T-cell depletion
January 14th, 2004
Hepatitis C and Schistosoma mansoni coinfections cause T-cell depletion. According to a study from the United States, "factors that influence the generation and maintenance of memory CD8(+) T cells are not fully understood. The homeostasis of memory T cells is highly dynamic and tightly regulated by various stimuli, including cytokines and antigen-major histocompatibility complex ligands. We characterized the hepatitis C virus (HCV)-specific CD8(+) T-cell responses in a cohort of HCV-infected individuals with or without Schistosoma mansoni coinfection from Egypt." "We observed a significantly decreased CD27(-) CD28(-) (late...
Source: Biotech Week (2004-01-14)
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