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Cancer Research UK
MSI-low is a real phenomenon that varies in frequency among cancer types
January 14th, 2004
MSI-L is rare in breast carcinomas, but does occur in colorectal, endometrial, and ovarian carcinomas, which are all part of the hereditary non-polyposis colon cancer (HNPCC) syndrome, researchers say. According to published research from England, "This study assessed whether low-level microsatellite instability (MSI-L) is a phenomenon specific to colorectal cancers or is also present in other tumor types. "Breast (grade III ductal and lobular), endometrial and ovarian carcinomas, as well as colorectal cancers, were analyzed for MSI-L using eight microsatellite markers," wrote S.E.R. Halford and colleagues, Cancer Research UK, Molecular & Population...
Source: Biotech Week (2004-01-14)
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