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Cancer Research UK



Rare genetic condition sheds light on body's cancer defenses



January 14th, 2004

A rare inherited condition has brought scientists a step closer to understanding how cells safeguard themselves from becoming cancerous.

People with Bloom syndrome - which is caused by inheriting faulty versions of a gene called BLM - are highly prone to developing cancer and must be monitored for the disease from a young age.

Although scientists knew the BLM gene played a role in stopping normal cells from becoming cancerous, it was not known how.

But in a new Nature report, Cancer Research UK scientists said that BLM stops a DNA repair process in cells from introducing errors that could cause cancer.

...


Source: Biotech Week (2004-01-14)

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