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Case Western Reserve University

Moxonidine effective for metabolic syndrome X treatment in rats

"Hypertension often coexists with hyperlipidemia, insulin resistance, and glucose intolerance, a comorbidity known as metabolic syndrome X," scientists in Cleveland explained. "Different antihypertensives have mixed effects on these associated abnormalities."

In a recent study, R.A. Velliquette and colleagues at Case Western Reserve University "compared three antihypertensives in the spontaneously hypertensive obese rat model of syndrome X."

"Moxonidine (4 mg/kg), an imidazoline and alpha₂ -adrenergic agonist,...

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