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Catholic University of Louvain



The cytokine interleukin-1beta is highly expressed in SIDS brains



January 14th, 2004

The cytokine interleukin-1beta is highly expressed in SIDS brains.

According to a study from Belgium, "cytokines modify neuronal function. Dysfunction in vital centers is reported in sudden infant death syndrome (SIDS).

"The authors detected high neuronal interleukin (IL)-1beta immunoreactivity in the arcuate and dorsal vagal nuclei in SIDS," wrote H. Kadhim and coauthors.

The researchers concluded: "This IL-1 overexpression might contribute to molecular interactions in brainstem neurovegetative centers, causing disturbed homeostatic control of cardiorespiratory and arousal responses, possibly leading to SIDS."

...


Source: Biotech Week (2004-01-14)

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