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Nippon Boehringer Ingelheim Co.



The angiogenic phenotypes of MT-8 and MT-9 murine tumors are different



January 14th, 2004

The angiogenic phenotypes of MT-8 and MT-9 murine tumors are different.

According to recent research published in the journal Microscopy and Microanalysis, "angiogenesis, a biologic process whereby endothelial cells divide and migrate to form new blood vessels, is a key step in tumor growth, invasion, and metastasis. In the present study, we investigated the differences in angioarchitecture between two different tumors induced by cloned cell lines (MT-8 and MT-9), derived from a transplantable rat malignant fibrous histiocytoma, by scanning electron microscopy of vascular corrosion casts. During a 3-week observation period after implantation, the growth of MT-8...


Source: Biotech Week (2004-01-14)

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