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Aarhus University
Chlamydia pneumoniae Cpn0796 examined, nature of secretion defined
July 6th, 2005
Recent research published from Denmark has reported on the secretion of Cpn0796 from Chlamydia pneumoniae into the host cell cytoplasm by an autotransporter mechanism. "By comparison of proteome profiles of purified C. pneumoniae and whole lysates of C. pneumoniae infected HEp-2 cells, an N-terminal fragment of the previously uncharacterized chlamydial protein Cpn0796 was identified as a secreted protein. A 38 kDa cleavage product of Cpn0796 was present in infected cells, whereas only the 65 kDa full-length Cpn0796 could be detected in purified Chlamydia," wrote B.B.S. Vandahl and colleagues, Aarhus University. "Confocal...
Source: Biotech Week (2005-07-06)
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