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Akita University



ABCA2 protein expression in vestibular schwannoma and peripheral nerves shown



July 6th, 2005

Recently published research from Japan has chronicled the expression of ABCA2 protein in human vestibular schwannoma and peripheral nerves.

"ABCA2, which belongs to the A subclass of the ATP-binding cassette (ABC) transporter superfamily, is predominantly expressed in the cytoplasm of oligodendrocytes and Schwann cells, the myelin-forming cells in brain and peripheral nerve, respectively.

"Here, we demonstrate by immunoblot and immunohistochemistry that ABCA2 is expressed in benign vestibular schwannomas, which contain neither axons nor compact myelin," wrote Y. Wang and colleagues, Akita University.

"The expression patterns of...


Source: Biotech Week (2005-07-06)

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