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Memorial Sloan-Kettering Cancer Center



Research add new data to cancer vaccines body of knowledge



July 6th, 2005

New findings from the United States, United Kingdom and Switzerland describe advances in cancer vaccines.

Study 1: Scientists compare antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn in a recent issue of Cancer Immunology Immunotherapy.

According a study from the United States, "We have demonstrated previously that the optimal method for inducing an antibody response against defined cancer antigens is covalent conjugation of the antigen to keyhole limpet hemocyanin (KLH) and use of the potent saponin adjuvant QS-21. Single molecules of glycolipids (tetrasaccharides,...


Source: Biotech Week (2005-07-06)

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